Abstract：
STUDY OBJECTIVE:To test the hypothesis that the change of body and head position affects upper airway patency during midazolam sedation. DESIGN:Clinical study using 30 healthy subjects. SETTING:Research unit for sleep study. INTERVENTIONS:We used a pressure-flow relationship to evaluate critical closing pressure (Pcrit) and upper airway resistance (Rua) in different condition of body and head position. A pressure-flow relationship was obtained in 3 body postures (supine, 15 degrees elevation, and 30 degrees elevation) and was obtained in 3 head positions (supine with the head in the neutral, supine with head extension, and supine position with head rotated). MEASUREMENTS:The pressure and inspiratory flow at subjects' nose mask were recorded. Polysomnographic parameters (electroencephalograms, electrooculograms, submental electromyograms, upper esophageal pressure, and plethysmogram) were also recorded. MAIN RESULTS:In experiment 1, 30 degrees elevation of the body significantly decreased Pcrit (P < 0.05) to -13.3 +/- 1.3 cm H(2)O compared with -8.2 +/- 1.4 cm H(2)O in supine condition without changing the slope (1/Rua). In experiment 2, head extension significantly decreased Pcrit (-12.5 +/- 1.3 cm H(2)O) (P < 0.05) compared with the value (-8.2 +/- 1.0 cm H(2)O) in supine condition without changing the slope (1/Rua). CONCLUSIONS:Our findings indicate that 30 degrees body elevation and head extension significantly decreased upper airway collapsibility during midazolam sedation and established the relative potency of maneuvers that maintain upper airway patency.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Ikeda H,Ayuse T,Oi Kdoi
10.1016/j.jclinane.2005.08.010subject
Has Abstractpub_date
2006-05-01 00:00:00pages
185-93issue
3eissn
0952-8180issn
1873-4529pii
S0952-8180(05)00338-7journal_volume
18pub_type
杂志文章abstract：:A young, healthy adult man exhibited naloxone-reversible, prolonged apnea after a 4-hour infusion of remifentanil, which was used as the opioid component of a general endotracheal anesthetic. Clinical experience and pharmacokinetic simulations indicate that the apnea was clearly atypical. ...
journal_title：Journal of clinical anesthesia
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doi：10.1016/j.jclinane.2006.05.024
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abstract：:Spinal cord injuries continue to be a devastating medical problem. By impairing voluntary and involuntary nervous system function, virtually every body system function is affected. However, pulmonary function alteration and respiratory complications continue to be the major causes of morbidity and mortality in patient...
journal_title：Journal of clinical anesthesia
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更新日期：2003-08-01 00:00:00
abstract：:We report a 31-year-old woman scheduled for a right frontal craniotomy and debulking of a recurrent grade 3 astrocytoma. Mannitol was given at the request of the surgeons. Peaked T waves were noted on electrocardiography, and electrolyte analysis showed hyperkalemia and hyponatremia. ...
journal_title：Journal of clinical anesthesia
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abstract：STUDY OBJECTIVE:Selecting candidates for residency positions is challenging and there is little research on the correlation between commonly used selection criteria and subsequent performance in anesthesiology. This study examined the association between the selection measures and post-recruitment performance in reside...
journal_title：Journal of clinical anesthesia
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更新日期：2017-06-01 00:00:00
abstract：:Oxymetazoline nasal spray is a potent alpha 1-adrenergic agonist commonly used to vasoconstrict blood vessels in the nasal mucosa. In this incident, oxymetazoline nasal spray 0.025% was administered to a 2-year-old patient during general anesthesia for nasal endoscopy. Severe hypertension with reflex bradycardia progr...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(95)00060-u
更新日期：1995-09-01 00:00:00
abstract：STUDY OBJECTIVE:To ascertain the optimal dose of trimethaphan camsylate administered by intravenous (i.v.) bolus injection for the control of hypertension and tachycardia during electroconvulsive therapy (ECT). DESIGN:Prospective, double blind, within-subject study. SETTING:Treating room of the psychiatric unit of th...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0952-8180(95)00192-1
更新日期：1996-03-01 00:00:00
abstract：:We present a case in which an anemic patient with religious objections to blood transfusion experienced three episodes of severe myocardial ischemia during the perioperative period. The first episode of ischemia was successfully treated by discontinuing isoflurane and resolving the hypotension. The second and third ep...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(96)00086-4
更新日期：1996-08-01 00:00:00
abstract：BACKGROUND:Operative hysteroscopy is accompanied by the use of distention medium. Its absorption can lead to volume overload and hemodynamic disturbances that can lead to serious complications. We investigated the impact of the type of anesthesia on decreasing these complications with the use of noninvasive thoracic bi...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
doi：10.1016/j.jclinane.2016.06.023
更新日期：2017-05-01 00:00:00
abstract：STUDY OBJECTIVE:To compare analgesia and opioid-related side effects of intrathecal morphine and intrathecal hydromorphone after elective Cesarean delivery. DESIGN:Retrospective, comparative study. SETTING:Labor and delivery unit of an academic hospital. PATIENTS:114 parturients age ≥ 18 years, presenting for electi...
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更新日期：2013-08-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(91)90095-5
更新日期：1991-11-01 00:00:00
abstract：STUDY OBJECTIVE:To compare a total intravenous (IV) anesthetic technique based on propofol and alfentanil with a commonly used anesthetic technique for craniotomy. DESIGN:Open-label, randomized, clinical study. SETTING:Neurosurgical clinic at a university hospital. PATIENTS:Forty patients, aged 18 to 55 years, sched...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1991-03-01 00:00:00
abstract：INTRODUCTION:There have been numerous reports studying the effect of neuraxial analgesia on breastfeeding success, but the results are inconsistent. METHODS:We performed a literature search in various databases for studies comparing neuraxial analgesia to non-neuraxial or no analgesia. Outcomes were the percentage of ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,评审
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更新日期：2021-02-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1991-01-01 00:00:00
abstract：STUDY OBJECTIVES:To track physician and nursing practice regarding preoperative pregnancy screening and testing in a setting where testing is the established policy. DESIGN:Prospective study. SETTING:University-affiliated, urban, tertiary care pediatric hospital. PATIENTS:261 menarcheal patients, aged 10 to 34 years...
journal_title：Journal of clinical anesthesia
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更新日期：2007-09-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2003-03-01 00:00:00
abstract：STUDY OBJECTIVE:Several factors such as lack of unidirectional, turbulent free laminar airflow, duration of surgery, patient warming system, or the number of health professionals in the OR have been shown or suspected to increase the number of airborne bacteria. The objective of this study was to perform a multivariate...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
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更新日期：2017-05-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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abstract：STUDY OBJECTIVE:To evaluate the efficacy and safety profile of paracetamol in comparison with tramadol for pain relief during active labor. DESIGN:Prospective, randomized, double-blind study. SETTING:Maternity Wing of the Postgraduate Institute of Medical Education and Research, Chandigarh. PATIENT:Sixty laboring, p...
journal_title：Journal of clinical anesthesia
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更新日期：2017-02-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2016-08-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
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更新日期：2004-08-01 00:00:00
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journal_title：Journal of clinical anesthesia
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更新日期：2010-09-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2007.10.012
更新日期：2008-05-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2017.02.002
更新日期：2017-05-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
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更新日期：2005-12-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
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更新日期：2014-09-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
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更新日期：2017-12-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(94)00015-v
更新日期：1995-02-01 00:00:00
abstract：STUDY OBJECTIVE:To determine the effects of respiratory acidosis and alkalosis by mechanical ventilation on the onset, duration, and recovery times of vecuronium. DESIGN:Randomized, prospective study. SETTING:Operating rooms in the Sapporo Medical University Hospital and Kitami Red Cross Hospital. PATIENTS:90 ASA ph...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(01)00361-0
更新日期：2002-03-01 00:00:00
