Abstract：
STUDY OBJECTIVE:To compare analgesia and opioid-related side effects of intrathecal morphine and intrathecal hydromorphone after elective Cesarean delivery. DESIGN:Retrospective, comparative study. SETTING:Labor and delivery unit of an academic hospital. PATIENTS:114 parturients age ≥ 18 years, presenting for elective Cesarean delivery. INTERVENTIONS:Patients who received 0.04 mg intrathecal hydromorphone were compared to a random sample of patients who received 0.1 mg intrathecal morphine for postoperative analgesia. MEASUREMENTS:The primary outcome was the presence of any opioid-related complication (pruritus, nausea or vomiting, respiratory depression) requiring treatment within 24 hours of intrathecal opioid administration. Secondary outcomes included total opioid consumption (in oral morphine equivalents) within 24 hours of intrathecal opioid administration and verbal pain score (0 = none, 10 = worst) at 4, 8, 12, 18, and 24 hours after intrathecal opioid administration. MAIN RESULTS:38 patients who received intrathecal hydromorphone 0.04 mg were compared with 76 patients given 0.1 mg of intrathecal morphine for elective Cesarean delivery. No significant differences in demographics were noted between groups. There were no statistically significant differences between the intrathecal hydromorphone and intrathecal morphine groups in overall frequency of opioid-related complications (50% vs. 34.2%; P = 0.11), 24-hour opioid consumption (33 mg oral morphine equivalent [OME] vs. 8 mg OME; P = 0.27), or pain scores at any time point up to 24 hours. CONCLUSIONS:Overall, analgesia and incidence of opioid-related side effects after 0.04 mg of intrathecal hydromorphone did not differ statistically from 0.1 mg of intrathecal morphine.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Beatty NC,Arendt KW,Niesen AD,Wittwer ED,Jacob AKdoi
10.1016/j.jclinane.2013.01.014subject
Has Abstractpub_date
2013-08-01 00:00:00pages
379-383issue
5eissn
0952-8180issn
1873-4529pii
S0952-8180(13)00175-Xjournal_volume
25pub_type
杂志文章abstract：:Hemodynamic instability as a result of altered baroreflex mechanism is common in surgeries involving manipulation around the carotid sheath. We report a case in which hypertensive crisis was associated with laryngectomy during general anesthesia. Perioperative use of vasoactive agents such as alpha(2) agonists may hel...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2006.12.011
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:Although parental presence during anesthesia induction is suggested to diminish operative stress level in children, there have been conflicting results about this strategy. The aim of this study was to evaluate the effects of maternal presence during induction on operative stress level in children who had ton...
journal_title：Journal of clinical anesthesia
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更新日期：2017-06-01 00:00:00
abstract：STUDY OBJECTIVE:To test the feasibility and efficacy of a new approach to paravertebral catheter placement in patients undergoing major surgery of the breast. DESIGN:Single-group, single-center observational study. SETTING:Operating room, postoperative recovery area, and normal ward of a university hospital. PATIENT...
journal_title：Journal of clinical anesthesia
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abstract：OBJECTIVE:The purpose of the present study was to compare the effects of inhalational anesthesia to those of total intravenous anesthesia on intraoperative electrically evoked compound action potential (e-ECAP) thresholds in children undergoing cochlear implantation. STUDY DESIGN:Randomized prospective study. SETTING...
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pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2016.10.008
更新日期：2017-02-01 00:00:00
abstract：STUDY OBJECTIVE:To determine whether a 300 micrograms dose of oral clonidine given 90 minutes prior to laryngoscopy and intubation provides hemodynamic protection from the stress of a brief (15-second) and/or a prolonged (45-second) laryngoscopy. DESIGN:Randomized, double-blind, placebo-controlled study. SETTING:Inpa...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0952-8180(93)90089-w
更新日期：1993-01-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate perioperative dual antiplatelet therapy management in patients with previously placed coronary stents. DESIGN:Retrospective medical record review. SETTING:Academic medical center. PATIENTS:A total of 1891 surgical cases performed at Vanderbilt University Medical Center in 2012 were evalua...
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abstract：STUDY OBJECTIVE:To compare postoperative nausea, emesis, analgesia, and recovery between propofol-ketamine and propofol-fentanyl in outpatient laparoscopic tubal ligations with general anesthesia. STUDY DESIGN:Prospective, randomized, blinded study. SETTING:Tertiary-care women's hospital. PATIENTS:120 ASA physical s...
journal_title：Journal of clinical anesthesia
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abstract：STUDY OBJECTIVE:To compare the work of breathing associated with the laryngeal mask airway (LMA) and tracheal tube (TT) in spontaneously breathing anesthetized patients. DESIGN:Randomized, prospective, controlled trial. SETTING:University teaching hospital. SUBJECTS:20 ASA physical status I and II patients scheduled...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(98)00026-9
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
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更新日期：1997-05-01 00:00:00
abstract：:We present the case report of a 49-year-old gentleman with a history of adenoid cystic carcinoma of the left nare status post curative bifrontal craniotomy, left lateral rhinotomy and medial maxillectomy, adjuvant radiotherapy, and orbital exenteration for optic neuropathy, complicated by medial wall dehiscence. His c...
journal_title：Journal of clinical anesthesia
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更新日期：2016-11-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of clinical anesthesia
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abstract：STUDY OBJECTIVE:To evaluate whether alkalizing local anesthetic with sodium bicarbonate reduces pain related to infiltration of local anesthetic during dorsal penile nerve block for circumcision. DESIGN:Prospective, randomized, double-blind, controlled study. SETTING:E. Wolfson Medical Center, Holon, Israel. PATIENT...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1999-11-01 00:00:00
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journal_title：Journal of clinical anesthesia
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更新日期：2001-09-01 00:00:00
abstract：STUDY OBJECTIVE:To assess the impact of intraoperative hemodynamics in the development of perioperative myocardial infarction (MI) and myocardial ischemia after noncardiac surgery. DESIGN:Single-center retrospective cohort study of surgical patients from 2007 to 2012. SETTING:Postanesthesia care unit, intensive care ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.05.009
更新日期：2016-11-01 00:00:00
abstract：STUDY OBJECTIVE:To determine how often pediatric anesthesiologists follow the American Heart Association (AHA) recommendations for the administration of prophylactic antibiotics to prevent bacterial endocarditis (BE). DESIGN:Questionnaires mailed to all members of the Society for Pediatric Anesthesia regarding their u...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(94)90109-0
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journal_title：Journal of clinical anesthesia
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abstract：OBJECTIVES:To determine if the infraclavicular brachial plexus block can be applied with lower volume of local anesthetic. DESIGN:Randomised, double-blinded clinical trial. PATIENTS:60 patients aged 5-15years with ASA I-II who underwent emergent or elective arm, forearm or hand operations were included in the study. ...
journal_title：Journal of clinical anesthesia
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abstract：:Propofol, a phenol compound with a short elimination half-life, was compared with thiopental and isoflurane for induction and maintenance of general anesthesia in 60 consenting ASA I, II, and III patients. The study was randomized and open label in design. Hemodynamically, the propofol patients showed a mean +/- SEM d...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of clinical anesthesia
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更新日期：2011-02-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
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更新日期：2003-11-01 00:00:00
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journal_title：Journal of clinical anesthesia
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doi：10.1016/j.jclinane.2004.08.013
更新日期：2005-08-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/0952-8180(95)00027-f
更新日期：1995-08-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-03-01 00:00:00
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更新日期：2016-06-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
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更新日期：2014-09-01 00:00:00
abstract：:This is a case of systemic ropivacaine toxicity from a sciatic nerve catheter. A 20-year-old patient after heart transplant with poor systemic perfusion on hemodialysis and multiple medications experienced local anesthetic systemic toxicity 72 hours after placement of a peripheral nerve catheter. The case demonstrates...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2015.03.021
更新日期：2015-06-01 00:00:00
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journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
doi：10.1016/0952-8180(95)00053-k
更新日期：1995-09-01 00:00:00
abstract：:Bispectral index is an accepted depth of anaesthesia monitor for guiding intraoperative hypnotic agent administration. Frontalis EMG displayed on BIS monitor may increase due to twitching of frontalis muscle. EMG increases are also known to cause artefactual increases in BIS values. We report a case of artefactual inc...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.11.005
更新日期：2017-02-01 00:00:00
abstract：:Acute respiratory failure in the perioperative period represents a frequent challenge to the anesthesiologist. The differential diagnosis is extensive and includes alterations on the pulmonary parenchyma, pulmonary vessels, airway, and cardiac system. Occasionally, two or more pathophysiological process superimpose. W...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/s0952-8180(01)00336-1
更新日期：2001-12-01 00:00:00
