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Alkalinization of mepivacaine does not alter onset of caudal anesthesia.

Abstract：

STUDY OBJECTIVE:To determine the effect of alkalinization of mepivacaine on onset of caudal anesthesia. DESIGN:Randomized, blind study. SETTING:Colon-Rectal Surgery Service of the Tertiary Center at Cleveland Clinic Foundation. PATIENTS:Young, healthy adults undergoing anal surgery. INTERVENTIONS:Addition of bicarbonate (study group) or saline (control group) to mepivacaine. MEASUREMENTS AND MAIN RESULTS:At the onset of sacral anesthesia, demographics were measured. A slightly faster onset was found in the study group (4.28 vs. 6.08 minutes), but this was not statistically significant. CONCLUSIONS:Alkalinization of mepivacaine does not significantly accelerate the onset of caudal anesthesia.

journal_name

J Clin Anesth

journal_title

Journal of clinical anesthesia

authors

Tetzlaff JE,Rothstein L

doi

10.1016/0952-8180(92)90134-m

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

301-3

issue

4

eissn

0952-8180

issn

1873-4529

pii

0952-8180(92)90134-M

journal_volume

4

pub_type

临床试验,杂志文章,随机对照试验

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