Abstract:
STUDY OBJECTIVE:To evaluate the cardiovascular changes following induction of anesthesia, laryngoscopy, and intubation in patients receiving a bolus dose of either eltanolone or propofol. DESIGN:Randomized, controlled, blind, prospective clinical study. SETTING:General operating theaters of a university hospital. PATIENTS:40 ASA status I and II patients scheduled for elective surgery. INTERVENTIONS:Patients were premedicated with oral temazepam 20 mg. Anesthesia was induced with either eltanolone 0.58 mg/kg or propofol 1.7 mg/kg, neuromuscular blockade was achieved with vecuronium 0.1 mg/kg, and anesthesia was maintained with enflurane 0.5% to 1.0% in nitrous oxide (67%). MEASUREMENTS AND MAIN RESULTS:Blood pressure was measured using an automatic oscillometric technique, heart rate (HR) was derived from the ECG, oxygen saturation was measured by pulse oximetry, and cardiac output (Q) was measured by a thoracic bioimpedance technique. Induction of anesthesia with either drug, eltanolone or propofol, decreased arterial systolic (SAP) and diastolic (DAP) blood pressure, Q, and stroke volume (SV). HR increased. Systemic vascular resistance (SVR) was unaltered. After laryngoscopy and intubation, SAP and DAP increased secondary to an increase in SVR. HR also increased; SV decreased in patients receiving eltanolone. Side effects (e.g., apnea occurring for more than 30 seconds, involuntary movements, limb hypertonus) occurred at a similar incidence with both treatments, but pain following injection was greater with propofol (59% vs. 9%). CONCLUSIONS:Patients receiving either eltanolone or propofol showed similar cardiovascular changes to induction of anesthesia, although there were greater increases in arterial pressure and HR in those patients receiving eltanolone.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Sear JW,Jewkes C,Wanigasekera Vdoi
10.1016/0952-8180(94)00026-zsubject
Has Abstractpub_date
1995-03-01 00:00:00pages
126-31issue
2eissn
0952-8180issn
1873-4529pii
0952-8180(94)00026-Zjournal_volume
7pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVES:To determine the psychometric outcomes of patients participating in an extensive patient-centered verification process before receiving sedation for regional anesthesia. DESIGN:Survey. SETTING:Perioperative areas of university-affiliated hospital. PATIENTS:Two hundred eligible patients scheduled for elect...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2014.10.009
更新日期:2015-05-01 00:00:00
abstract::Visualization of thromboembolic material in the pulmonary artery is often difficult on transesophageal echocardiography, especially in the left pulmonary artery, because of the position of the left main bronchus. We present a case in which thromboembolic material within the midleft pulmonary artery was incidentally di...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2007.06.026
更新日期:2008-03-01 00:00:00
abstract:STUDY OBJECTIVE:To perform a prospective audit of the modified guideline for the management postdural puncture headache (PDPH) and present the results at 6 months. DESIGN:Prospective single-center audit. SETTING:University hospital. PATIENTS:24 adult, ASA physical status 1, 2, and 3 patients presenting with PDPH in ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/j.jclinane.2014.03.006
更新日期:2014-11-01 00:00:00
abstract::Valvular heart disease in a parturient presenting for Cesarean section is challenging. A 25 year old primigravida parturient with severe mitral stenosis, mild mitral regurgitation, mild aortic regurgitation, and mild pulmonary arterial hypertension required Cesarean delivery after developing pulmonary edema. Low-dose ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2013.12.009
更新日期:2014-05-01 00:00:00
abstract::Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects, even in patients with impaired cardiac function. With currently available opioids, precise titration of dose to effect is difficult, and high doses result in drug accumulatio...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/s0952-8180(96)00179-1
更新日期:1996-12-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether postoperative wound infiltration with local anesthetics combined with fentanyl improves analgesia following breast surgery; and to investigate awakening and postoperative nausea/vomiting. DESIGN:Prospectively randomized clinical study. SETTING:University hospital. PATIENTS:45 ASA...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(02)00511-1
更新日期:2003-03-01 00:00:00
abstract:STUDY OBJECTIVE:To assess intubating conditions without neuromuscular blocking drugs, to determine the relation between the dose of rocuronium and the probability of achieving excellent or at least good (good or excellent) intubating conditions with the intubating laryngeal mask airway (ILMA), and finally, to determine...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jclinane.2004.06.009
更新日期:2005-05-01 00:00:00
abstract:STUDY OBJECTIVE:To compare values for two whole blood viscoelastic coagulation tests, thromboelastography (TEG) and Sonoclot analysis (Sonoclot R Coagulation Analyzer, Sienco, Inc., Morrison, CO), between healthy parturients and nonparturients. DESIGN:Prospective study. SETTING:University hospital. PATIENTS:41 healt...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(93)90108-q
更新日期:1993-09-01 00:00:00
abstract::Induction of general anesthesia in the agitated or combative mentally retarded patient is challenging. Oral ketamine facilitated the smooth and safe induction of anesthesia in an adult mentally retarded patient with a history of violent behavior toward health care providers. The oral administration of ketamine is an e...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(90)90065-b
更新日期:1990-03-01 00:00:00
abstract::Placement of a central venous catheter into an internal thoracic vein occurs in approximately 2% of all catheterizations. A case in which a pulmonary artery catheter was trapped within the internal thoracic vein during orthotopic heart transplantation is presented. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2010.03.010
更新日期:2011-05-01 00:00:00
abstract:STUDY OBJECTIVE:To examine the risk of perioperative stroke on in-hospital morbidity and mortality in staged coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) procedures. DESIGN:The National Inpatient Sample (NIS) database was used to extract data on all patients who underwent staged CABG CEA pro...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2017.03.024
更新日期:2017-06-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether vasodilators such as sodium nitroprusside (SNP) and trimethaphan (TMP) produce a pressure difference between the radial artery and the brachial artery during epidural plus general anesthesia or simple general anesthesia. DESIGN:Randomized study and prospective study. SETTING:Opera...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(95)00199-9
更新日期:1996-05-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether adding ephedrine to propofol is as effective as adding lidocaine at reducing injection pain, and its effects on hemodynamics. DESIGN:Randomized, double-blinded, controlled trial. SETTING:District general hospital in the United Kingdom. PATIENTS:156 adult, ASA physical status I, I...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2008.06.018
更新日期:2009-02-01 00:00:00
abstract:STUDY OBJECTIVE:To document the effects of compromised respiratory function on oxygen saturation (SpO2) after cesarean section via the telemetric pulse oximetry network (TPON) for 24 continuous hours. DESIGN:Prospective study. SETTING:Postpartum ward of a university hospital. PATIENTS:ASA physical status I or II par...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(94)90009-4
更新日期:1994-03-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the optimal time in which to make intraocular pressure (IOP) measurements in children following tracheal intubation. DESIGN:Randomized, controlled trial. SETTING:Operating rooms of a tertiary-care children's hospital. PATIENTS:Thirteen healthy children undergoing elective strabismus corr...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90226-d
更新日期:1991-07-01 00:00:00
abstract:STUDY OBJECTIVE:To define the optimal dose of lidocaine to be added to propofol to reduce the incidence of pain during its injection. DESIGN:Double-blind, randomized, placebo-controlled study. SETTING:Medical center operating rooms. PATIENTS:135 ASA I and II female patients undergoing minor outpatient surgery. INTE...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(96)00133-x
更新日期:1996-11-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the incidence of major complications in patients undergoing regional anesthesia (RA) in China. DESIGN:Multicenter prospective survey. SETTING:Eleven teaching hospitals in China. PATIENTS AND INTERVENTIONS:A total of 106,569 patients undergoing RA from April 1, 2009, to April 30, 2011, we...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jclinane.2016.01.022
更新日期:2016-06-01 00:00:00
abstract:STUDY OBJECTIVE:Our hypothesis was that a pre-operative posteromedial quadratus lumborum (QL) block would reduce postoperative morphine consumption and provide superior analgesia in the setting of multimodal analgesia compared with a lateral transversus abdominis plane (TAP) block for laparoscopic colorectal surgery. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2020.109716
更新日期:2020-06-01 00:00:00
abstract:STUDY OBJECTIVE:To establish the analgesic effective doses as defined as a visual analog pain scale (VAS) of at least 10 for 95% of parturients (ED95) receiving either epidural fentanyl or sufentanil with bupivacaine 0.125% for labor analgesia. DESIGN:Double-blind, randomized controlled study. SETTING:Two tertiary-ca...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(98)00113-5
更新日期:1998-12-01 00:00:00
abstract:STUDY OBJECTIVES:To determine whether the first-attempt tracheal intubation incidence using the GlideScope videolaryngoscope is higher in patients with predicted increased risk of difficult laryngoscopy, and to assess the ability of other a priori defined standard risk factors to predict first-attempt intubation succes...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2011.03.006
更新日期:2011-12-01 00:00:00
abstract::The benefits of cardiopulmonary exercise testing have been well established. Certain patient groups present challenges for conducting such a test. We were presented with a patient with a permanent tracheostomy at the preoperative assessment clinic. We describe our technique in overcoming the problem of connecting him ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2016.04.019
更新日期:2016-11-01 00:00:00
abstract:STUDY OBJECTIVE:To determine how often pediatric anesthesiologists follow the American Heart Association (AHA) recommendations for the administration of prophylactic antibiotics to prevent bacterial endocarditis (BE). DESIGN:Questionnaires mailed to all members of the Society for Pediatric Anesthesia regarding their u...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(94)90109-0
更新日期:1994-01-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the methods used to teach surgical airway management to residents. DESIGN:Electronic mail survey instrument. SETTING:Academic medical center. PARTICIPANTS:82 (of a possible 132) United States residency program directors. MEASUREMENTS:Data including whether instruction in surgical airway...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2010.10.002
更新日期:2011-06-01 00:00:00
abstract::Two patients are presented who underwent successful combined L1 and L2 paravertebral blocks as part of an anesthetic technique for hip arthroscopy. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2008.04.012
更新日期:2008-09-01 00:00:00
abstract::A 48-year-old man with end-stage liver disease and aortic stenosis (AS), was being evaluated for liver transplantation. This report focuses on the question of which medical problem to correct first, the end-stage liver disease or the AS. Risk factors for surgical correction of AS and liver transplantation are reviewed...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/s0952-8180(98)00018-x
更新日期:1998-05-01 00:00:00
abstract:STUDY OBJECTIVE:To test the hypothesis that midazolam potentiates thiopental sodium-induced unconsciousness. DESIGN:Randomized, double-blind study. SETTING:A university medical center. PATIENTS:Fifty nonpremedicated ASA physical status I and II adult patients scheduled for eye surgery. INTERVENTIONS:Intravenous (IV...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90177-o
更新日期:1991-09-01 00:00:00
abstract:STUDY OBJECTIVE:To develop categories of behavior that define an applicant's aptitude for anesthesia, and to attempt to determine the relative importance of these behaviors to successful residency performance. DESIGN:Prospective open study. SETTING:Anesthesia residencies at three midwest university teaching hospitals...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(97)00195-5
更新日期:1997-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the consequences of opioid use for postoperative pain management and the degree to which these consequences may be reduced or minimized with opioid-sparing or opioid-replacement techniques. DESIGN:Literature review relating to the economics of postoperative pain management. Comparisons betw...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/s0952-8180(02)00372-0
更新日期:2002-08-01 00:00:00
abstract:STUDY OBJECTIVE:Breast cancer is the most common malignancy of women all over the world. In this study, we compared the effects of ultrasound-guided modified pectoral nerve (PECS) block and erector spinae plane (ESP) block on postoperative opioid consumption, pain scores, and intraoperative fentanyl need of patients un...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2018.10.040
更新日期:2019-05-01 00:00:00
abstract:STUDY OBJECTIVE:Evaluate feasibility of 1-day OR management course for anesthesiology residents and determine if course content increases trust in OR management science. DESIGN:Pre- and post-course survey evaluations. SETTING:OR management course. PATIENTS:University of Florida anesthesiology residents. INTERVENTIO...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2018.12.045
更新日期:2019-08-01 00:00:00