Thromboelastography and Sonoclot analysis in the healthy parturient.

Abstract:

STUDY OBJECTIVE:To compare values for two whole blood viscoelastic coagulation tests, thromboelastography (TEG) and Sonoclot analysis (Sonoclot R Coagulation Analyzer, Sienco, Inc., Morrison, CO), between healthy parturients and nonparturients. DESIGN:Prospective study. SETTING:University hospital. PATIENTS:41 healthy, nonpregnant females and full-term nonlaboring and laboring parturients. INTERVENTIONS:Blood samples for TEG and Sonoclot analysis were taken from all patients. TEG tracings were analyzed for reaction time (R), coagulation time (RK), the difference between RK and R (K), clot formation rate (alpha degree), and maximum amplitude (MA) values. Sonoclot tracings were analyzed for onset, rate increases, peak, and rate decreases values. MEASUREMENTS AND MAIN RESULTS:All TEG values were significantly different between nonpregnant females and parturients (p < 0.05). Sonoclot analysis showed that the parturients had a significantly decreased onset and increased primary slope (rate increases) in comparison to the nonpregnant females (p < 0.05). CONCLUSION:The differences found in the parturients reflect a hypercoagulable state. If these tests are to be used in evaluating obstetric patients, the results should be compared with values obtained for healthy parturients, not healthy nonparturients.

journal_name

J Clin Anesth

authors

Steer PL,Krantz HB

doi

10.1016/0952-8180(93)90108-q

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

419-24

issue

5

eissn

0952-8180

issn

1873-4529

pii

0952-8180(93)90108-Q

journal_volume

5

pub_type

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