Is cell salvage safe in liver resection? A pilot study.

Abstract:

STUDY OBJECTIVE:To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). DESIGN:Observational study. SETTING:Operating room in a university hospital. MEASUREMENTS:6 patients undergoing hemihepatectomy or aortobifemoral bypass with intraoperative blood loss of more than 800 mL. Samples were drawn from the central venous catheter, from the reservoir of a CS recovery system, and from the processed blood in each patient to determine interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor (TNF), complement C3a, and the terminal complement complex C5b-9. Microbiological analysis included colony count after cultivation in aerobic and anaerobic medium as well as enrichment culture for 6 days. MAIN RESULTS:In the hemihepatectomy group, levels of IL-6, C3a, and C5b-9 were significantly higher in the reservoir than in samples obtained from the central venous catheter. After the washing procedure, levels of IL-6, C3a, and C5b-9 were lower in the liver resection group than in each patient's own plasma levels. In all patients undergoing aortobifemoral bypass and in 5 patients undergoing hemihepatectomy, blood samples were sterile or showed growth of commensal skin microflora in low numbers (coagulase-negative staphylococci or propionibacteria). In one patient in the liver resection group, we could not exclude contamination with intestinal flora. CONCLUSION:Cell salvaged blood in liver resection seems to be safe for retransfusion with respect to cytokine release and complement activation, but requires further investigation in regard to bacterial contamination.

journal_name

J Clin Anesth

authors

Schmidt A,Sues HC,Siegel E,Peetz D,Bengtsson A,Gervais HW

doi

10.1016/j.jclinane.2009.01.012

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

579-84

issue

8

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(09)00279-7

journal_volume

21

pub_type

杂志文章
  • Usefulness of routine preoperative testing: a prospective single-observer study.

    abstract:STUDY OBJECTIVE:The purpose of this study is to determine whether routine preoperative testing has a usefulness not previously recognized in a small preliminary study to decide if such a hypothesis might be worthy of testing in a larger study. DESIGN:Single-observer, prospective, observational study. SETTING:Tertiary...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jclinane.2004.04.002

    authors: Mantha S,Roizen MF,Madduri J,Rajender Y,Shanti Naidu K,Gayatri K

    更新日期:2005-02-01 00:00:00

  • Delayed awakening following inadvertent high-dose remifentanil infusion in a 13 year old patient.

    abstract::We report the case of a 13 year old patient who received 3.0 mg of remifentanil during a 50-minute surgical procedure as a result of a dosage miscalculation. The patient failed to awaken at the conclusion of the procedure and showed signs of opioid overdose. She recovered spontaneously two hours later. ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2010.07.005

    authors: Barak M,Greenberg Z,Danino J

    更新日期:2011-06-01 00:00:00

  • Use of patient-controlled analgesia with alfentanil for extracorporeal shock wave lithotripsy.

    abstract:STUDY OBJECTIVE:To compare the efficacy of patient-controlled analgesia (PCA) to physician-controlled analgesia in patients undergoing extracorporeal shock wave lithotripsy (ESWL). DESIGN:Prospective, randomized trial. SETTING:New Jersey Kidney Stone Treatment Center at Robert Wood Johnson University Hospital, New Br...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0952-8180(95)00008-6

    authors: Kortis HI,Amory DW,Wagner BK,Levin R,Wilson E,Levin A,Pitchford DE,Pollak P

    更新日期:1995-05-01 00:00:00

  • Pooled analysis of three large clinical trials to determine the optimal dose of dolasetron mesylate needed to prevent postoperative nausea and vomiting. The Dolasetron Prophylaxis Study Group.

    abstract:STUDY OBJECTIVE:To identify the maximally effective dolasetron dose (i.e., maximum efficacy with minimum adverse events) for prevention of postoperative nausea and vomiting (PONV) using the statistical power generated in a pooled patient sample from three large, nearly identical clinical trials. DESIGN:Three randomize...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0952-8180(99)00123-3

    authors: Philip BK,McLeskey CH,Chelly JE,McKenzie R,Kovac AL,Diemunsch P,DuBois DM

    更新日期:2000-02-01 00:00:00

  • Treatment of severe lactic acidosis during the pre-anhepatic stage of liver transplant surgery with intraoperative hemodialysis.

    abstract::Severe uncompensated lactic acidosis manifesting during the pre-anhepatic stage of orthotopic liver transplant surgery is an uncommon event, but it poses serious concern because of the additional lactate production and impaired elimination by the liver that develops during the anhepatic and allograft reperfusion stage...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2009.07.013

    authors: Vitin A,Muczynski K,Bakthavatsalam R,Martay K,Dembo G,Metzner J

    更新日期:2010-09-01 00:00:00

  • Bevel direction of epidural needles reliably predicts direction of catheter placement and contrast spread in human cadavers: results of a pilot study.

    abstract:STUDY OBJECTIVE:To confirm the relationship between bevel orientation, catheter direction, and radiopaque contrast spread in the lumbar region. DESIGN:Pilot cadaver study. SETTING:Anatomy laboratory of a university hospital. MEASUREMENTS:Cadavers were randomized to two groups of 4 cadavers each. In Group 1, needle b...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2014.04.004

    authors: Shaparin N,Bernstein J,White RS,Kaufman A

    更新日期:2014-12-01 00:00:00

  • Effect of propofol for induction and ondansetron with or without dexamethasone for the prevention of nausea and vomiting after major gynecologic surgery.

    abstract:STUDY OBJECTIVES:To test the hypothesis that for major gynecologic surgery the combination of propofol for induction, ondansetron, and dexamethasone would be a more effective antiemetic combination than propofol for induction, ondansetron, and saline; and to determine if a propofol induction of anesthesia improved our ...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0952-8180(96)00215-2

    authors: McKenzie R,Riley TJ,Tantisira B,Hamilton DL

    更新日期:1997-02-01 00:00:00

  • Bacterial endocarditis prophylaxis: what is recommended and what is practiced?

    abstract:STUDY OBJECTIVE:To determine how often pediatric anesthesiologists follow the American Heart Association (AHA) recommendations for the administration of prophylactic antibiotics to prevent bacterial endocarditis (BE). DESIGN:Questionnaires mailed to all members of the Society for Pediatric Anesthesia regarding their u...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/0952-8180(94)90109-0

    authors: Schwartz RE,Lowe DA,Stayer SA,Pasquariello CA,Schlichting CM

    更新日期:1994-01-01 00:00:00

  • Determination of the diagnostic value of the Modified Mallampati Score, Upper Lip Bite Test and Facial Angle in predicting difficult intubation: A prospective descriptive study.

    abstract:BACKGROUND:Difficult intubation is a significant cause of mortality and morbidity related to anesthesia. We decided to evaluate the value of Modified Mallampati Score, Upper Lip Bite Test and Facial Angle in the prediction of difficult intubation. METHODS:In a prospective descriptive study, data from 132 patients who ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2016.12.010

    authors: Mahmoodpoor A,Soleimanpour H,Golzari SE,Nejabatian A,Pourlak T,Amani M,Hajmohammadi S,Hosseinzadeh H,Esfanjani RM

    更新日期:2017-02-01 00:00:00

  • Hemodynamic stability and patient satisfaction after anesthetic induction with thiopental sodium, ketamine, thiopental-fentanyl, and ketamine-fentanyl.

    abstract:STUDY OBJECTIVE:To examine three commonly used anesthetic induction regimens (thiopental sodium, ketamine, and thiopental plus fentanyl) and one newly described regimen (ketamine plus fentanyl) with respect to hemodynamic stability and patient satisfaction. DESIGN:Randomized, double-blind study. SETTING:University-af...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0952-8180(93)90141-z

    authors: Katz RI,Lagasse RS,Levy A,Alexander G

    更新日期:1993-03-01 00:00:00

  • Unilateral Horner's syndrome and brachial plexus anesthesia during lumbar epidural blockade.

    abstract::Horner's syndrome is a rare side effect of epidural analgesia. In association with ipsilateral brachial plexus block, it has only been reported once before, in French. Unilateral blockade has also been reported, although its etiology is unclear and may be multifactorial. The patient described here experienced an asymm...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/s0952-8180(02)00399-9

    authors: Holzman RS

    更新日期:2002-09-01 00:00:00

  • The pharmacokinetics of remifentanil.

    abstract::Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects, even in patients with impaired cardiac function. With currently available opioids, precise titration of dose to effect is difficult, and high doses result in drug accumulatio...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/s0952-8180(96)00179-1

    authors: Michelsen LG,Hug CC Jr

    更新日期:1996-12-01 00:00:00

  • Noninvasive positive pressure ventilation in the management of acute respiratory failure due to osteogenesis imperfecta.

    abstract::The development of acute respiratory failure (ARF) secondary to respiratory tract infection is a common event in patients affected with osteogenesis imperfecta type III. Noninvasive positive pressure ventilation (NPPV) is increasingly administered to treat severe ARF of various origin. The use of NPPV in two patients ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2011.04.011

    authors: Arcaro G,Braccioni F,Gallan F,Marchi MR,Vianello A

    更新日期:2012-02-01 00:00:00

  • Spinal epidural hematoma occurrence in the absence of known risk factors: a case series.

    abstract::Spinal epidural hematoma in the absence of coagulopathy or anticoagulation therapy is an extremely rare occurrence, with a reported incidence of less than 1 in 1 million. We present seven cases of documented epidural hematoma in the absence of coagulopathy or anticoagulation therapy to alert the clinician to consider ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2003.12.007

    authors: Cullen DJ,Bogdanov E,Htut N

    更新日期:2004-08-01 00:00:00

  • Admixture of ephedrine to offset side effects of propofol: a randomized, controlled trial.

    abstract:STUDY OBJECTIVE:To determine whether adding ephedrine to propofol is as effective as adding lidocaine at reducing injection pain, and its effects on hemodynamics. DESIGN:Randomized, double-blinded, controlled trial. SETTING:District general hospital in the United Kingdom. PATIENTS:156 adult, ASA physical status I, I...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2008.06.018

    authors: Austin JD,Parke TJ

    更新日期:2009-02-01 00:00:00

  • The optimal effective concentration of lidocaine to reduce pain on injection of propofol.

    abstract:STUDY OBJECTIVE:To determine the optimal concentration of lidocaine that reduces pain on injection of a propofol-lidocaine mixture. DESIGN:Prospective, randomized, double-blinded, clinical investigation. SETTING:Medical center, university teaching hospital. PATIENTS:240 ASA physical status I and II female outpatient...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(99)00040-9

    authors: Ho CM,Tsou MY,Sun MS,Chu CC,Lee TY

    更新日期:1999-06-01 00:00:00

  • Patient satisfaction with continued versus divided anesthetic care.

    abstract:STUDY OBJECTIVE:To evaluate patient acceptability of continued versus divided anesthetic care. DESIGN:Patient satisfaction ratings with continuous and divided anesthetic care were assessed by patient questionnaire. In addition, the effect of training anesthesia personnel in communication regarding divided anesthesia c...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2006.04.004

    authors: Harms C,Nübling M,Langewitz W,Kindler CH

    更新日期:2007-02-01 00:00:00

  • Propofol-ketamine versus propofol-fentanyl for outpatient laparoscopy: comparison of postoperative nausea, emesis, analgesia, and recovery.

    abstract:STUDY OBJECTIVE:To compare postoperative nausea, emesis, analgesia, and recovery between propofol-ketamine and propofol-fentanyl in outpatient laparoscopic tubal ligations with general anesthesia. STUDY DESIGN:Prospective, randomized, blinded study. SETTING:Tertiary-care women's hospital. PATIENTS:120 ASA physical s...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(02)00391-4

    authors: Vallejo MC,Romeo RC,Davis DJ,Ramanathan S

    更新日期:2002-09-01 00:00:00

  • Quadriparesis from air emboli during percutaneous nephrolithotomy.

    abstract::Quadriparesis is a potentially catastrophic complication during operative procedures. It may result from a number of different types of central nervous system insults. A case of quadriparesis following an otherwise unremarkable percutaneous nephrolithotomy surgery is reported. The quadriparesis resulted from multiple ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2014.01.007

    authors: Hegland DL,Canales BK,Katz RI

    更新日期:2014-06-01 00:00:00

  • Comparison of cisatracurium-induced neuromuscular blockade between immediate postpartum and nonpregnant patients.

    abstract:STUDY OBJECTIVES:To evaluate and compare cisatracurium-induced neuromuscular blockade and intubating conditions between immediate postpartum (PP) and nonpregnant (NP) patients. DESIGN:Prospective control study. SETTINGS:University Hospital Center. PATIENTS:44 ASA physical status I and II patients: 22 immediate postp...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0952-8180(01)00226-4

    authors: Pan PH,Moore C

    更新日期:2001-03-01 00:00:00

  • Use of key words as an adjunctive learning tool improves learning during a perioperative medicine rotation for anesthesiology residents.

    abstract::Designing a successful block rotation for anesthesiology residents requires not only an appropriate curriculum but also a set of teaching tools, which promote learning. Traditional clinical rotations in Anesthesiology residencies emphasize clinical teaching, supported by interaction with staff. Since Perioperative Med...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/s0952-8180(00)00136-7

    authors: Tetzlaff JE,Ryckman JV

    更新日期:2000-05-01 00:00:00

  • Determination of the analgesic dose-response relationship for epidural fentanyl and sufentanil with bupivacaine 0.125% in laboring patients.

    abstract:STUDY OBJECTIVE:To establish the analgesic effective doses as defined as a visual analog pain scale (VAS) of at least 10 for 95% of parturients (ED95) receiving either epidural fentanyl or sufentanil with bupivacaine 0.125% for labor analgesia. DESIGN:Double-blind, randomized controlled study. SETTING:Two tertiary-ca...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(98)00113-5

    authors: Herman NL,Sheu KL,Van Decar TK,Rubin JD,Gadalla F,Koff HD,Reynolds JE

    更新日期:1998-12-01 00:00:00

  • Anesthesiology in the Belgian health care environment.

    abstract::This article focuses on anesthesiology practice in the context of Belgian health care. The first part describes the organization of Belgian health care, the role of private and public initiatives, the division of responsibilities between the different health authorities, the financing mechanisms, and the central role ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/0952-8180(94)90081-7

    authors: Vleugels AM

    更新日期:1994-07-01 00:00:00

  • Systemic hemodynamic effects of sequential pneumatic compression of the lower limbs: a prospective study in healthy volunteers.

    abstract:STUDY OBJECTIVE:To evaluate the effects on systemic hemodynamics of sequential pneumatic compression of the lower limbs in healthy volunteers. DESIGN:Prospective, self-controlled, volunteer study. SETTING:University teaching hospital. PATIENTS:11 healthy volunteers, aged 25 +/- 1.3 years. INTERVENTIONS AND MEASUREM...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jclinane.2008.02.005

    authors: Fanelli G,Zasa M,Baciarello M,Mazzani R,Di Cianni S,Rossi M,Casati A

    更新日期:2008-08-01 00:00:00

  • Comparison of spinal anesthesia with combined sciatic-femoral nerve block for outpatient knee arthroscopy.

    abstract:STUDY OBJECTIVE:To compare spinal anesthesia and combined sciatic-femoral nerve block for outpatient knee arthroscopy. DESIGN:Prospective, randomized, controlled study. SETTING:Postoperative recovery area at a university-affiliated medical center. PATIENTS:50 ASA physical status I and II adult outpatients undergoing...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2008.04.003

    authors: Montes FR,Zarate E,Grueso R,Giraldo JC,Venegas MP,Gomez A,Rincón JD,Hernadez M,Cabrera M

    更新日期:2008-09-01 00:00:00

  • Action of β-endorphin and nonsteroidal anti-inflammatory drugs, and the possible effects of nonsteroidal anti-inflammatory drugs on β-endorphin.

    abstract::This study aimed to review research on the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on β-endorphin. NSAIDs are commonly used as anti-inflammatory and analgesic drugs. They are well known for inducing peripheral analgesia by inhibiting cyclooxygenase (COX). However, an increasing number of studies have ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinane.2016.12.016

    authors: Luan YH,Wang D,Yu Q,Chai XQ

    更新日期:2017-02-01 00:00:00

  • Endothelium-dependent vascular smooth muscle control.

    abstract::Recent pharmacologic evidence supports the importance of the integrity of the endothelium in modulating vascular reactivity. The endothelial cells produce one or more endothelium derived relaxing factor(s) or EDRF that cause relaxation of vascular smooth muscle cells through production of cyclic guanosine monophosphat...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/0952-8180(88)90033-5

    authors: Husain M,Moss J

    更新日期:1988-01-01 00:00:00

  • The economic impact of opioids on postoperative pain management.

    abstract:STUDY OBJECTIVE:To evaluate the consequences of opioid use for postoperative pain management and the degree to which these consequences may be reduced or minimized with opioid-sparing or opioid-replacement techniques. DESIGN:Literature review relating to the economics of postoperative pain management. Comparisons betw...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/s0952-8180(02)00372-0

    authors: Philip BK,Reese PR,Burch SP

    更新日期:2002-08-01 00:00:00

  • The predictive value of pre-recruitment achievement on resident performance in anesthesiology.

    abstract:STUDY OBJECTIVE:Selecting candidates for residency positions is challenging and there is little research on the correlation between commonly used selection criteria and subsequent performance in anesthesiology. This study examined the association between the selection measures and post-recruitment performance in reside...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2017.03.052

    authors: Chen F,Arora H,Martinelli SM,Teeter E,Mayer D,Zvara DA,Passannante A,Smith KA

    更新日期:2017-06-01 00:00:00

  • Topical anesthesia versus retrobulbar block for cataract surgery: the patients' perspective.

    abstract:STUDY OBJECTIVES:To compare patients' perception of topical anesthesia (TA) with combined peribulbar and retrobulbar block (PRBB) for cataract surgery. DESIGN:Prospective, randomized, controlled, cross-over observational study. SETTING:Private clinic. PATIENTS:98 ASA physical status I and II patients presenting for ...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(00)00117-3

    authors: Boezaart A,Berry R,Nell M

    更新日期:2000-02-01 00:00:00