Abstract:
STUDY OBJECTIVES:To evaluate and compare cisatracurium-induced neuromuscular blockade and intubating conditions between immediate postpartum (PP) and nonpregnant (NP) patients. DESIGN:Prospective control study. SETTINGS:University Hospital Center. PATIENTS:44 ASA physical status I and II patients: 22 immediate postpartum (PP) patients (<48 hours after delivery) scheduled for elective postpartum tubal ligation and 22 nonpregnant (NP) patients (>40 weeks from prior pregnancy) scheduled for elective gynecological procedures. INTERVENTIONS:General anesthesia was induced intravenously (IV) with thiopental sodium 5 mg/kg, fentanyl 2.0 to 3.0 ug/kg, midazolam 0.015 to 0.025 mg/kg, and cisatracurium 0.2 mg/kg. Evoked electromyographic responses of the adductor pollicis muscle were obtained by supra-maximal train-of-four stimulation of the ulnar nerve every ten seconds via surface electrodes at the wrist. Intubation was attempted at 90 s after completion of cisatracurium administration and again at 120 seconds if the first attempt was unsuccessful. The intubating anesthesiologist assessed the intubating conditions with four variables: jaw relaxation, vocal cord immobility and exposure, patient/diaphragmatic movement, and overall intubating impression. Intraoperative anesthetic was maintained with 30% oxygen, 70% nitrous oxide, and 1% end-tidal isoflurane, as tolerated. Patient temperature was maintained at 35.5 degrees to 37.5 degrees Celsius (C), and end-tidal carbon dioxide at 30 to 36 mmHg. MEASUREMENTS AND MAIN RESULTS:The mean onset times to 50%, 90%, and maximal T(1) depression and mean time to 25% T(1) recovery in the PP group (68 +/- 19 sec, 110 +/- 26 sec, 147 +/- 32 sec, 60 +/- 6 min) were significantly less than those in the NP group (80 +/- 17 sec, 131 +/- 28 sec, 181 +/- 44 sec, 69 +/- 12 min), respectively (p < 0.05). All patients were successfully intubated on the first attempt at 90 seconds. 91% of the NP group and 81% of the PP group had excellent overall intubating conditions. CONCLUSIONS:This is the first published control study to compare the effects of cisatracurium between NP and PP patients. The results suggest that the mean onset time and clinical duration of cisatracurium are significantly shorter in immediate postpartum patients than those in nonpregnant female patients.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Pan PH,Moore Cdoi
10.1016/s0952-8180(01)00226-4subject
Has Abstractpub_date
2001-03-01 00:00:00pages
112-7issue
2eissn
0952-8180issn
1873-4529pii
S0952-8180(01)00226-4journal_volume
13pub_type
临床试验,杂志文章abstract::We report two patients with a history of dural puncture who developed paradoxical postural cerebrospinal fluid leak-induced headache. The patients' headache worsened when they were in the recumbent position, and it improved when they were placed upright. Both patients had a history of migraine headache. The patients w...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2008.01.011
更新日期:2008-08-01 00:00:00
abstract::During surgical removal of tumors of the skull base or cerebellopontine angle with brainstem compression, the vagus nerve is at a high risk for injury that can result in permanent or transient swallowing and speech dysfunction. Intramuscular recording of cricothyroid muscle can be used for vagal nerve mapping during i...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2015.01.002
更新日期:2015-05-01 00:00:00
abstract:STUDY OBJECTIVES:To evaluate the effects of fentanyl on the cardiorespiratory system in elderly patients undergoing cataract surgery with phacoemulsification method. DESIGN:Randomized, prospective, double-blind study. SETTING:University hospital. PATIENTS:70 ASA physical status I, II, and III patients (>60 years) wh...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jclinane.2003.05.008
更新日期:2004-03-01 00:00:00
abstract::Endometriosis occurs in 5% to 10% of women of childbearing age and involves the proliferation of endometrial tissue outside the uterine cavity. Thoracic endometriosis is the most frequent extrapelvic manifestation of endometriosis, numbering some 100 reported cases. It may include spontaneous pneumothorax, hemoptysis,...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(01)00350-6
更新日期:2002-02-01 00:00:00
abstract:STUDY OBJECTIVES:To determine whether the first-attempt tracheal intubation incidence using the GlideScope videolaryngoscope is higher in patients with predicted increased risk of difficult laryngoscopy, and to assess the ability of other a priori defined standard risk factors to predict first-attempt intubation succes...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2011.03.006
更新日期:2011-12-01 00:00:00
abstract::Induction of general anesthesia in the agitated or combative mentally retarded patient is challenging. Oral ketamine facilitated the smooth and safe induction of anesthesia in an adult mentally retarded patient with a history of violent behavior toward health care providers. The oral administration of ketamine is an e...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(90)90065-b
更新日期:1990-03-01 00:00:00
abstract:STUDY OBJECTIVE:The objective was to present a proof of concept for a simple and consistently successful ultrasonograpy (US)-guided technique to block the internal branch of the superior laryngeal nerve (iSLN). DESIGN:This was a volunteer and cadaver anatomy study. SETTING:The setting was an anesthesiology department...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2015.07.016
更新日期:2015-11-01 00:00:00
abstract::This study examines whether epidural anesthesia is more effective than general anesthesia using an inhalation agent in controlling cardiovascular responses during femoral-popliteal bypass surgery. Nineteen patients were randomized into two groups: general anesthesia (n = 10) and epidural anesthesia (n = 9). The patien...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(90)90056-9
更新日期:1990-03-01 00:00:00
abstract:STUDY OBJECTIVE:To analyze the effects of epidural analgesia for labor when dystocia occurs. DESIGN:Retrospective cohort study. SETTING:Academic health center. PATIENTS:641 low risk, nulliparous women in spontaneous labor. INTERVENTIONS:406 (63%) women received epidurals analgesia and 253 (37%) did not. Sixty women...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/s0952-8180(97)00222-5
更新日期:1998-02-01 00:00:00
abstract:STUDY OBJECTIVE:To characterize the approach of academic chairs of anesthesiology in leading and managing their departments, and to gain insights into what they considered the most difficult challenges as chairs. DESIGN:Internet-based survey instrument conducted during July and August of 2006. SETTING:Academic medica...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2008.08.009
更新日期:2009-03-01 00:00:00
abstract::A rare case of postoperative cardiac arrest in an otherwise healthy, 49-year-old female patient who had a laparoscopic hysterectomy, is presented. The cause of cardiac arrest was due to massive pulmonary embolism, which was detected by transesophageal echocardiography. Laparoscopic surgery is regarded as a less invasi...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2003.02.007
更新日期:2003-11-01 00:00:00
abstract::Placement of a central venous catheter into an internal thoracic vein occurs in approximately 2% of all catheterizations. A case in which a pulmonary artery catheter was trapped within the internal thoracic vein during orthotopic heart transplantation is presented. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2010.03.010
更新日期:2011-05-01 00:00:00
abstract:STUDY OBJECTIVE:To compare a multiport, firm-tipped, close-ended, epidural catheter (Portex catheter) with a uniport, open-ended, soft-tipped, wire-reinforced catheter (Arrow catheter) in obstetric patients. STUDY DESIGN:Prospective data collection for intradepartmental quality assurance. SETTING:Obstetric unit in a ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(00)00116-1
更新日期:2000-03-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the incidence of major complications in patients undergoing regional anesthesia (RA) in China. DESIGN:Multicenter prospective survey. SETTING:Eleven teaching hospitals in China. PATIENTS AND INTERVENTIONS:A total of 106,569 patients undergoing RA from April 1, 2009, to April 30, 2011, we...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jclinane.2016.01.022
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of epidural, spinal, and general anesthesia on pain after lower-limb amputation. DESIGN:Cross-sectional survey. SETTING:Postamputation clinic. PATIENTS:150 patients who were evaluated one to 24 months after their lower-limb amputation. INTERVENTIONS:Patients received epidural, spin...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2006.03.021
更新日期:2006-12-01 00:00:00
abstract::The specialty of anesthesia was established in German medicine in 1953 with the founding of the Germany Society of Anaesthesia and the inclusion of a "specialist in anesthesia" as part of the German medical training requirements. Anesthesia training is offered to students and residents and as a part of continuing educ...
journal_title:Journal of clinical anesthesia
pub_type: 历史文章,杂志文章
doi:10.1016/0952-8180(91)90169-n
更新日期:1991-05-01 00:00:00
abstract:STUDY OBJECTIVE:To quantify global coagulation and establish normal ranges for the celite-activated thrombelastograph (TEG) in healthy pediatric patients. DESIGN:Prospective observational study. SETTING:Operating suite of a university-based hospital. PATIENTS:110 healthy pediatric patients in four age groups and 25 ...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/s0952-8180(00)00238-5
更新日期:2001-02-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effect of intravenous administration of prostaglandin E1 (PGE1) in inducing controlled hypotension during general anesthesia. DESIGN:Randomized, prospective study. SETTING:Inpatient surgery at a university hospital. PATIENTS:57 ASA physical status I and II patients scheduled for tota...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(93)90125-x
更新日期:1993-07-01 00:00:00
abstract:STUDY OBJECTIVE:To identify the maximally effective dolasetron dose (i.e., maximum efficacy with minimum adverse events) for prevention of postoperative nausea and vomiting (PONV) using the statistical power generated in a pooled patient sample from three large, nearly identical clinical trials. DESIGN:Three randomize...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0952-8180(99)00123-3
更新日期:2000-02-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate airway changes in patients undergoing surgery in the prone position. DESIGN:Single-arm observational study. PATIENTS:Patients between 18 to 65 years old, scheduled for prone spinal surgery; 74 patients were enrolled and 54 patients were analyzed. INTERVENTION:The initial airway examinatio...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2014.04.010
更新日期:2014-12-01 00:00:00
abstract:STUDY OBJECTIVE:To develop a rapid online test of graft liver function during liver transplantation. DESIGN:Prospective, observational study. SETTING:University hospital transplant unit. PATIENTS:17 adult patients with end-stage liver disease who underwent liver transplantation surgery. INTERVENTIONS:Rocuronium inf...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/s0952-8180(03)00061-8
更新日期:2003-06-01 00:00:00
abstract:INTRODUCTION:There have been numerous reports studying the effect of neuraxial analgesia on breastfeeding success, but the results are inconsistent. METHODS:We performed a literature search in various databases for studies comparing neuraxial analgesia to non-neuraxial or no analgesia. Outcomes were the percentage of ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/j.jclinane.2020.110105
更新日期:2021-02-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the accuracy of cardiac index (CI) as measured by echo-transesophageal Doppler monitoring (echo-TDM) with CI measured by the transpulmonary thermodilution technique. DESIGN:Prospective, observational study. SETTING:University hospital. PATIENTS:16 patients scheduled for elective lung canc...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2009.03.013
更新日期:2010-03-01 00:00:00
abstract::Although digoxin remains one of the most widely prescribed drugs in the United States, potential pharmacodynamic and pharmacokinetic interactions between this compound and other drugs, diseases, and events commonly encountered in the perioperative period remain largely unappreciated. Furthermore, the therapeutic benef...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/0952-8180(92)90170-6
更新日期:1992-09-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effects of fresh gas flow on inspired gas composition during low-flow anesthesia. DESIGN:Randomized trial with 2-hour observation periods in patients assigned to one of three groups. SETTING:Inpatient surgery clinic at a medical center. PATIENTS:Thirty-six patients undergoing abdomin...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(92)90214-l
更新日期:1992-11-01 00:00:00
abstract::We report a case of guide wire loss and migration after central venous access for spinal deformity surgery. Guide wire migration was noticed on a follow-up full spine x-ray 69 days postoperatively. Percutaneous retrieval was successfully performed using endovascular techniques. With this case report, we want to highli...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2015.04.005
更新日期:2015-08-01 00:00:00
abstract:STUDY OBJECTIVE:To ascertain if coughing during emergence from general anesthesia can be suppressed with a modified endotracheal tube. DESIGN:Randomized, double-blind, controlled study. SETTING:Operating rooms at a university hospital. PATIENTS:46 adult ASA physical status I, II, and III patients requiring elective ...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(01)00299-9
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Cardiac arrest is associated with very high mortality and causes neurological dysfunction in the survivors. Therapeutic hypothermia is one of the recommended modality in the postarrest management. However, recent findings question its benefit in postarrest management. This meta-analysis has been conceptualiz...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jclinane.2016.03.001
更新日期:2016-09-01 00:00:00
abstract:STUDY OBJECTIVE:To test the hypothesis that midazolam potentiates thiopental sodium-induced unconsciousness. DESIGN:Randomized, double-blind study. SETTING:A university medical center. PATIENTS:Fifty nonpremedicated ASA physical status I and II adult patients scheduled for eye surgery. INTERVENTIONS:Intravenous (IV...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90177-o
更新日期:1991-09-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the value of clinical history and preoperative coagulation tests. DESIGN:Prospective, multicenter clinical investigation. SETTING:Twenty-four centers over a one-year period. PATIENTS:1,706 children scheduled for tonsillectomy. In 1, 479 out of 1,706 children, studied age was ranged from ...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/s0952-8180(00)00164-1
更新日期:2000-06-01 00:00:00