Abstract:
BACKGROUND:Cardiac arrest is associated with very high mortality and causes neurological dysfunction in the survivors. Therapeutic hypothermia is one of the recommended modality in the postarrest management. However, recent findings question its benefit in postarrest management. This meta-analysis has been conceptualized to quantify clinical benefit of therapeutic hypothermia in post-cardiac arrest patients. METHODS:Prospective, randomized, and quasi-randomized controlled trials comparing the efficacy of therapeutic hypothermia in post-cardiac arrest adult population with a post-cardiac arrest management protocol that does not include therapeutic hypothermia were included in this meta-analysis. Two authors independently searched PubMed, PubMed Central, Scopus, and Central Register of Clinical Trials of the Cochrane Collaboration for potentially eligible trials. RESULTS:Data of 1399 patients from 6 controlled trials have been included in this systematic review and meta-analysis. Therapeutic hypothermia does not provide any benefit in favorable neurological outcome (P=.06; odds ratio, 1.80; 95% confidence interval [CI], 0.97-3.35; n=1384), in survival at hospital discharge (P=.58; odds ratio, 1.16; 95% CI, 0.69-1.96; n=1399), and in long-term survival (P=.36; odds ratio, 1.32; 95% CI, 0.73-2.39; n=1292). Therapeutic hypothermia also increases incidence of pneumonia (P=.02; odds ratio, 1.30; 95% CI, 1.04-1.64; n=1204; number needed to harm, 15). CONCLUSION:Therapeutic hypothermia in the post-cardiac arrest management protocol does not provide any benefit in favorable neurological outcome, survival to hospital discharge, and long term survival. Incidence of pneumonia may be increased with the use of therapeutic hypothermia.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Bhattacharjee S,Baidya DK,Maitra Sdoi
10.1016/j.jclinane.2016.03.001subject
Has Abstractpub_date
2016-09-01 00:00:00pages
225-32eissn
0952-8180issn
1873-4529pii
S0952-8180(16)30006-Xjournal_volume
33pub_type
杂志文章,meta分析,评审abstract:STUDY OBJECTIVE:To determine if acquired long QT syndrome following right or left, radical or modified, neck dissections result in malignant arrhythmias or deaths. DESIGN:Prospective study. SETTING:Inpatient head and neck service of the Massachusetts Eye and Ear Infirmary. PATIENTS:69 patients who underwent extensiv...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(94)00015-v
更新日期:1995-02-01 00:00:00
abstract::Swedish anesthesiology is greatly indebted to the preeminent American anesthesiologist, and first professor of anesthesiology in the world, Ralph M. Waters. It was in part because of the influence and teaching of this great pioneer that modern anesthesiology became firmly established in Sweden. Approximately 60 reside...
journal_title:Journal of clinical anesthesia
pub_type: 传,历史文章,杂志文章
doi:10.1016/0952-8180(94)90063-9
更新日期:1994-05-01 00:00:00
abstract:STUDY OBJECTIVE:To examine and compare the mechanism of injury, diagnostic findings, initial methods of airway management, and outcome of patients who had upper airway injuries. DESIGN:A retrospective review of hospital records. SETTING:A large metropolitan, university-affiliated trauma center. PATIENTS:Forty-six ca...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(91)90003-6
更新日期:1991-03-01 00:00:00
abstract:STUDY OBJECTIVE:Physician-led multidisciplinary care coordination decreases hospital-associated care needs. We aimed to determine whether such care coordination can show benefits through the posthospital discharge period for elective hip surgery. DESIGN:Time Series of prospectively recorded and historical data. SETTI...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2020.110072
更新日期:2021-02-01 00:00:00
abstract:STUDY OBJECTIVE:Perioperative fasting guidelines differ in their approaches to chewing gum in the preoperative period. Current recommendations range from canceling the surgery to proceeding with it. Given this lack of consensus, we performed gastric ultrasound assessments in healthy volunteers before and after a standa...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2019.01.021
更新日期:2019-09-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effect-site target concentration (C(et)) of remifentanil that provides optimal conditions for patients and operators during cataract surgery during monitored anesthesia care using a target controlled infusion (TCI) of propofol and remifentanil. DESIGN:Prospective, randomized, double-bl...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2010.02.007
更新日期:2010-11-01 00:00:00
abstract::Obstructive sleep apnea (OSA) is associated with postoperative airway obstruction, hypoxemia, cardiac arrhythmias, cardiorespiratory arrest, hypoxic encephalopathy, and death. Three cases highlighting important issues in patients with OSA are presented that occurred prior to and after implementation of an OSA protocol...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2008.08.023
更新日期:2009-06-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the quality of analgesia and the severity of side effects of intrathecal morphine administered for a dose range of 0.0 to 0.4 mg for postcesarean analgesia with low-dose bupivacaine. DESIGN:Double-blind, randomized study. SETTING:University hospital. PATIENTS:100 ASA physical status I and...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2007.07.010
更新日期:2008-05-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the optimal time in which to make intraocular pressure (IOP) measurements in children following tracheal intubation. DESIGN:Randomized, controlled trial. SETTING:Operating rooms of a tertiary-care children's hospital. PATIENTS:Thirteen healthy children undergoing elective strabismus corr...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90226-d
更新日期:1991-07-01 00:00:00
abstract::The most frequent and acute complications of subclavian vein catheterization are arterial puncture to the subclavian artery and pneumothorax. We report an arterial puncture directly to the pulmonary artery in infant during subclavian vein catheterization. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2007.10.012
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:When dexmedetomidine is used in patients undergoing spinal anesthesia, high incidence of bradycardia in response to parasympathetic activation is reported. Therefore, we aimed to evaluate the effectiveness of atropine premedication for preventing the incidence of bradycardia and the hemodynamic effect on pati...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2016.07.012
更新日期:2016-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate airway changes in patients undergoing surgery in the prone position. DESIGN:Single-arm observational study. PATIENTS:Patients between 18 to 65 years old, scheduled for prone spinal surgery; 74 patients were enrolled and 54 patients were analyzed. INTERVENTION:The initial airway examinatio...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2014.04.010
更新日期:2014-12-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the hemodynamic effects of two different concentrations of pentastarch hydroxyethyl starch (HES; 200/0.5) solutions with a 4% human albumin solution for fluid resuscitation. DESIGN:Open-label, randomized, controlled study. SETTING:Medical-surgical intensive care unit. PATIENTS:34 consecuti...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2008.05.022
更新日期:2008-11-01 00:00:00
abstract:STUDY OBJECTIVE:To measure the parameter of job satisfaction among anesthesiologists. DESIGN:Survey instrument. SETTING:Academic anesthesiology departments in the United States. SUBJECTS:320 anesthesiologists who attended the annual meeting of the ASA in 2009 (95% response rate). MEASUREMENTS AND MAIN RESULTS:The a...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2013.01.007
更新日期:2013-06-01 00:00:00
abstract:STUDY OBJECTIVE:To establish a useful ultrasonic approach to the epidural space so as to optimize pre-puncture diagnostics. DESIGN:Prospective study. SETTING:University clinic. PATIENTS:60 participants (19 to 34 years of age), 40 healthy volunteers (20 male, 20 female) and 20 parturients. INTERVENTIONS:Ultrasound s...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/s0952-8180(01)00245-8
更新日期:2001-05-01 00:00:00
abstract:INTRODUCTION:There is currently no consensus regarding the minimum threshold platelet count to ensure safe neuraxial procedures. Numerous reports describe the safe performance of lumbar punctures in severely thrombocytopenic patients but reports of neuraxial anesthetic procedures in thrombocytopenic patients are limite...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2019.109666
更新日期:2020-05-01 00:00:00
abstract::This case report describes a patient who became asystolic after electroconvulsive therapy. The report describes the prolonged resuscitative events that lasted 54 minutes and discusses the effectiveness of chest compressions and the importance of monitoring the acid-base balance. The report also stresses the importance...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(02)00344-6
更新日期:2002-05-01 00:00:00
abstract:STUDY OBJECTIVE:Preoperative anxiety is commonly reported by people undergoing surgery. A significant number of studies have found a correlation between preoperative anxiety and post-operative morbidity. Various methods of complementary and alternative medicine (CAM) were found to be effective in alleviating preoperati...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2015.10.017
更新日期:2016-03-01 00:00:00
abstract::A 30-year-old parturient requested epidural analgesia during labor. Immediately after the epidural space was presumably identified using the loss-of-resistance-to-air technique, she reported severe back pain, followed by neck pain, which progressed to severe unrelenting headache. An emergency computerized tomographic ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(91)90188-s
更新日期:1991-09-01 00:00:00
abstract::High frequency ventilation has been claimed to improve the efficiency of extracorporeal shock wave lithotripsy (ESWL) by minimizing the movement of urinary stones during the procedure. A ventilatory mode, QRS-activated ventilation, was developed in which the stones remain motionless during the delivery of shock waves....
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(89)90025-1
更新日期:1989-01-01 00:00:00
abstract::The perioperative management of a patient receiving a bilateral hand transplant is presented. The anesthetic management required careful fluid administration, homeothermic temperature maintenance, and postoperative analgesia. The role of different anesthesia subspecialties is highlighted. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2012.11.004
更新日期:2013-05-01 00:00:00
abstract:STUDY OBJECTIVE:To correlate tracheal width as measured by ultrasound with width measured by computed tomography (CT), and to evaluate the possible role of ultrasound in the selection of the proper size of left-sided double-lumen endotracheal tubes (LDLTs). DESIGN:Two independent, prospective, observational clinical s...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2007.11.002
更新日期:2008-06-01 00:00:00
abstract::We report an interaction of a transesophageal atrial pacemaker (TAP) with a permanently implanted pacemaker in a cardiac patient who had undergone ablative therapy for atrial tachyarrhythmia 5 years earlier. The patient's permanent A-V pacemaker was completely inhibited by the TAP, and there was loss of ventricular co...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(99)00107-5
更新日期:1999-12-01 00:00:00
abstract::Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects, even in patients with impaired cardiac function. With currently available opioids, precise titration of dose to effect is difficult, and high doses result in drug accumulatio...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/s0952-8180(96)00179-1
更新日期:1996-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate patient acceptability of continued versus divided anesthetic care. DESIGN:Patient satisfaction ratings with continuous and divided anesthetic care were assessed by patient questionnaire. In addition, the effect of training anesthesia personnel in communication regarding divided anesthesia c...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2006.04.004
更新日期:2007-02-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the intraoperative effects and recovery characteristics when either midazolam or propofol was used for sedation during local or regional anesthesia. DESIGN:Open-label, randomized study with blinded observer assessing recovery data. SETTING:Outpatients undergoing elective surgical procedures...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90203-y
更新日期:1991-01-01 00:00:00
abstract:STUDY OBJECTIVE:To identify the maximally effective dolasetron dose (i.e., maximum efficacy with minimum adverse events) for prevention of postoperative nausea and vomiting (PONV) using the statistical power generated in a pooled patient sample from three large, nearly identical clinical trials. DESIGN:Three randomize...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0952-8180(99)00123-3
更新日期:2000-02-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the incidence of major complications in patients undergoing regional anesthesia (RA) in China. DESIGN:Multicenter prospective survey. SETTING:Eleven teaching hospitals in China. PATIENTS AND INTERVENTIONS:A total of 106,569 patients undergoing RA from April 1, 2009, to April 30, 2011, we...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jclinane.2016.01.022
更新日期:2016-06-01 00:00:00
abstract::A rare case of postoperative cardiac arrest in an otherwise healthy, 49-year-old female patient who had a laparoscopic hysterectomy, is presented. The cause of cardiac arrest was due to massive pulmonary embolism, which was detected by transesophageal echocardiography. Laparoscopic surgery is regarded as a less invasi...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2003.02.007
更新日期:2003-11-01 00:00:00
abstract::This is a case of systemic ropivacaine toxicity from a sciatic nerve catheter. A 20-year-old patient after heart transplant with poor systemic perfusion on hemodialysis and multiple medications experienced local anesthetic systemic toxicity 72 hours after placement of a peripheral nerve catheter. The case demonstrates...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2015.03.021
更新日期:2015-06-01 00:00:00