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Major complications of regional anesthesia in 11 teaching hospitals of China: a prospective survey of 106,569 cases.

Abstract：

STUDY OBJECTIVE:To determine the incidence of major complications in patients undergoing regional anesthesia (RA) in China. DESIGN:Multicenter prospective survey. SETTING:Eleven teaching hospitals in China. PATIENTS AND INTERVENTIONS:A total of 106,569 patients undergoing RA from April 1, 2009, to April 30, 2011, were involved. MEASUREMENT:Information on patients, types of surgery, and RA techniques was collected with a standardized chart. After RA, the patients were followed up by an investigator in each center for 1 to 3 weeks according to the patient's condition. Data were integrated and analyzed with a structured query language server system. MAIN RESULTS:Among the patients undergoing RA, 37 developed major complications, including Horner syndrome (n = 9; 0.84/10,000), recurrent laryngeal nerve blockade (n = 6; 0.56/10,000), cardiac arrest (n = 1; 0.09/10,000), hematoma (n = 2; 0.19/10,000), seizures (n = 5; 0.46/10,000), catheter break (n = 1; 0.09/10,000), paraplegia (n = 1; 0.09/10,000), cauda equina syndrome (n = 2; 0.19/10,000), and extensive neuraxial block (n = 10; 0.94/10,000). The incidence of major RA complications varied from 0.8/10,000 to 18.8/10,000 among centers and was highest in cervical plexum block. Plastic surgery had the highest incidence of complications (19.0/10,000), most of which were recurrent extensive neuraxial block. The total incidence of major RA complications was 3.47/10,000. CONCLUSION:This large, multicenter, prospective survey revealed the incidence of major complications after RA in China's hospitals. Although severe complication like cardiac arrest is rare, it is distressing and challenging. Hence, there is still a room to improve on daily basis to further reduce complications related to RA.

journal_name

J Clin Anesth

journal_title

Journal of clinical anesthesia

authors

Huo T,Sun L,Min S,Li W,Heng X,Tang L,Zhu S,Dong H,Wang Q,Xiong L

doi

10.1016/j.jclinane.2016.01.022

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

154-61

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(16)00095-7

journal_volume

pub_type

杂志文章,多中心研究

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Major complications of regional anesthesia in 11 teaching hospitals of China: a prospective survey of 106,569 cases.