Abstract：
STUDY OBJECTIVE:To determine whether a new Sonoclot-based, aprotinin-insensitive activated clotting time (aiACT) assay yields stable results over a broad range of aprotinin concentrations. DESIGN:Prospective trial conducted on in vitro blood samples. SETTING:Tertiary-care teaching medical center. PARTICIPANTS:19 healthy adult volunteers. INTERVENTIONS:Whole blood samples were collected from volunteers. Heparin (2 U/mL) and escalating concentrations of aprotinin of 160 to 500 kallikrein inhibitory units (KIU)/mL were added in vitro. MEASUREMENTS AND MAIN RESULTS:Celite ACT, kaolin ACT, and aiACT assays were completed. The aiACT showed stable activated clotting time (ACT) results on heparinized, noncitrated blood with added aprotinin (P = nonsignificant). In contrast, celite ACT and kaolin ACT were greatly prolonged when aprotinin was added to heparinized, noncitrated, and citrated blood (P < 0.05). The aiACT had consistent results at all aprotinin concentrations (P = nonsignificant). CONCLUSIONS:Aprotinin (160, 320, and 500 KIU/mL) significantly prolongs the ACT value with celite and kaolin activators but not with the aprotinin-insensitive activator.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Dong Y,Nuttall GA,Oliver WC Jr,Agarwal S,Ereth MHdoi
10.1016/j.jclinane.2007.03.003subject
Has Abstractpub_date
2007-09-01 00:00:00pages
424-8issue
6eissn
0952-8180issn
1873-4529pii
S0952-8180(07)00173-0journal_volume
19pub_type
杂志文章abstract：STUDY OBJECTIVE:To evaluate the safety and efficacy of single inferior injection peribulbar block administered by anesthesiologists prior to cataract surgery. DESIGN:Retrospective chart review. SETTING:Freestanding surgery center (teaching). PATIENTS:1,074 consecutive patients who were treated over a two-year period...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
doi：10.1016/s0952-8180(97)00005-6
更新日期：1997-06-01 00:00:00
abstract：STUDY OBJECTIVE:To characterize respiratory dynamics during emergence from propofol-remifentanil anesthesia using noninvasive respiratory inductance plethysmography (RIP). DESIGN:Observational pilot study. SETTING:Operating room in a university-affiliated teaching hospital. PATIENTS:50 ASA physical status 1, 2, and ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2012.06.025
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Postoperative residual neuromuscular blockade (RNMB) is a common complication in the postanesthesia care unit (PACU), but also one of the most controversial issues. Many studies and trials demonstrated that some methods and techniques can reduce the incidence and the extent of the phenomenon. STUDY OBJECTIV...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2016.07.031
更新日期：2016-12-01 00:00:00
abstract：STUDY OBJECTIVE:To study the impact of adding simulation-based education to the pre-intervention mandatory hospital efforts aimed at decreasing central venous catheter-related blood stream infections (CRBSI) in intensive care units (ICU). DESIGN:Pre- and post-intervention retrospective observational investigation. SE...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2012.04.006
更新日期：2012-11-01 00:00:00
abstract：:With the advent of safety needles to prevent inadvertent needle sticks in the operating room (OR), a potentially new issue has arisen. These needles may result in coring, or the shaving off of fragments of the rubber stopper, when the needle is pierced through the rubber stopper of the medication vial. These fragments...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2013.10.007
更新日期：2014-03-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the cardiovascular changes following induction of anesthesia, laryngoscopy, and intubation in patients receiving a bolus dose of either eltanolone or propofol. DESIGN:Randomized, controlled, blind, prospective clinical study. SETTING:General operating theaters of a university hospital. PA...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0952-8180(94)00026-z
更新日期：1995-03-01 00:00:00
abstract：STUDY OBJECTIVE:To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). DESIGN:Observational study. SETTING:Operating room in a university hospital. MEASUREMENTS:6 patients undergoing hemihepatectomy...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2009.01.012
更新日期：2009-12-01 00:00:00
abstract：STUDY OBJECTIVE:To examine the risk of perioperative stroke on in-hospital morbidity and mortality in staged coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) procedures. DESIGN:The National Inpatient Sample (NIS) database was used to extract data on all patients who underwent staged CABG CEA pro...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2017.03.024
更新日期：2017-06-01 00:00:00
abstract：STUDY OBJECTIVE:Some outpatient procedures are performed under sedation with dexmedetomidine, although the effect of dexmedetomidine on cognitive function remains unclear. This study investigated the effect of dexmedetomidine on cognitive function in healthy volunteers. DESIGN:Observation study in volunteers. SETTING...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.03.017
更新日期：2016-09-01 00:00:00
abstract：STUDY OBJECTIVE:To investigate whether the type of anesthetic agent administered affects the antitussive effect of remifentanil. DESIGN:Prospective randomized study. SETTING:Operating room of a university hospital. PATIENTS:78 ASA physical status 1 and 2 women, aged 20 to 65 years, who were scheduled to undergo a th...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2014.02.002
更新日期：2014-09-01 00:00:00
abstract：:A parturient presented at 35 weeks' gestation with worsening neurological symptoms caused by syringomyelia. She underwent urgent cesarean delivery. The etiology and anesthetic considerations for an obstetrical patient with syringomyelia are discussed. ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2011.03.007
更新日期：2011-12-01 00:00:00
abstract：STUDY OBJECTIVE:Several factors such as lack of unidirectional, turbulent free laminar airflow, duration of surgery, patient warming system, or the number of health professionals in the OR have been shown or suspected to increase the number of airborne bacteria. The objective of this study was to perform a multivariate...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2017.02.008
更新日期：2017-05-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate patient satisfaction and patient reported anaesthesia related outcome parameters after outpatient surgery. DESIGN:A three-year (2013-2016) observational study. SETTING:A surgical day care centre embedded in a tertiary care, university hospital. PATIENTS:Adult Dutch-speaking patients who u...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2017.09.007
更新日期：2017-12-01 00:00:00
abstract：:Arterial misplacement of the Swan-Ganz catheter occurs occasionally and usually can be easily detected. However, in some special clinical settings, the problem may become more complicated. We report a case of chronic obstructive pulmonary disease in which, because of severe hypoxemia, systemic hypotension, and pulmona...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(95)00032-d
更新日期：1995-06-01 00:00:00
abstract：STUDY OBJECTIVE:The aim of this 12-year case series was to review the drugs used during anesthetic management of patients with diagnosis of or risk criteria for Brugada syndrome (BrS), and to document any possible association between these drugs and arrhythmogenic activity or unexplained hemodynamic instability. DESIG...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.09.031
更新日期：2017-02-01 00:00:00
abstract：:Induction of general anesthesia in the agitated or combative mentally retarded patient is challenging. Oral ketamine facilitated the smooth and safe induction of anesthesia in an adult mentally retarded patient with a history of violent behavior toward health care providers. The oral administration of ketamine is an e...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(90)90065-b
更新日期：1990-03-01 00:00:00
abstract：STUDY OBJECTIVES:To investigate the hypothesis that the combination of ondansetron and droperidol would be more effective than droperidol alone in reducing nausea and vomiting. DESIGN:Randomized, doubleblind study. SETTING:Magee-Womens Hospital, Pittsburgh, Pennsylvania. PATIENTS:160 healthy, ASA physical status I a...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(97)00188-8
更新日期：1998-02-01 00:00:00
abstract：STUDY OBJECTIVE:Evaluate feasibility of 1-day OR management course for anesthesiology residents and determine if course content increases trust in OR management science. DESIGN:Pre- and post-course survey evaluations. SETTING:OR management course. PATIENTS:University of Florida anesthesiology residents. INTERVENTIO...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2018.12.045
更新日期：2019-08-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the accuracy and precision of estimation of partial pressure of carbon dioxide (Pa(CO2)) using end-tidal or transcutaneous CO2 (TcP(CO2)) measurements during mechanical ventilation in the elderly patient. DESIGN:A prospective, observational study was conducted. SETTINGS:The study was done ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2006.02.007
更新日期：2006-09-01 00:00:00
abstract：STUDY OBJECTIVES:To examine the possible pharmacodynamic interaction of propofol and sufentanil with respect to the induction of loss of consciousness. DESIGN:Prospective, randomized, double-blinded study. SETTING:University hospital. PATIENTS:30 female, ASA physical status I and II patients undergoing elective gyne...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(99)00076-8
更新日期：1999-08-01 00:00:00
abstract：:We investigate an incident in which a carbon dioxide absorber caused difficulty with ventilation. The problem as it developed throughout the anesthetic, and clues that led to the determination that the carbon dioxide canister was the problem, is discussed. ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2007.06.018
更新日期：2008-02-01 00:00:00
abstract：:In December 2001, the United States Food and Drug Administration (FDA) added a "black box" warning to the labeling for droperidol stating that all doses, even those typically used for postoperative nausea and vomiting, were potentially associated with malignant ventricular dysrhythmias, including torsade de pointes. T...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/s0952-8180(02)00445-2
更新日期：2002-12-01 00:00:00
abstract：:Bispectral index is an accepted depth of anaesthesia monitor for guiding intraoperative hypnotic agent administration. Frontalis EMG displayed on BIS monitor may increase due to twitching of frontalis muscle. EMG increases are also known to cause artefactual increases in BIS values. We report a case of artefactual inc...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.11.005
更新日期：2017-02-01 00:00:00
abstract：STUDY OBJECTIVE:To provide a contemporary medicolegal analysis of claims brought against anesthesia providers in the United States related to neuraxial blocks for surgery and obstetrics. DESIGN:In this retrospective analysis, we analyzed closed claims data from the Controlled Risk Insurance Company (CRICO) Comparative...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2019.03.013
更新日期：2019-11-01 00:00:00
abstract：STUDY OBJECTIVE:We evaluated the efficacy of a multidisciplinary approach to reduce postoperative complications and 1-year mortality in patients, undergoing hip fracture surgery and the impact of surgical delay on mortality. DESIGN:A non-randomized intervention study with a historical control group (CG). SETTING:Duri...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
doi：10.1016/j.jclinane.2018.09.029
更新日期：2019-03-01 00:00:00
abstract：:Endometriosis occurs in 5% to 10% of women of childbearing age and involves the proliferation of endometrial tissue outside the uterine cavity. Thoracic endometriosis is the most frequent extrapelvic manifestation of endometriosis, numbering some 100 reported cases. It may include spontaneous pneumothorax, hemoptysis,...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/s0952-8180(01)00350-6
更新日期：2002-02-01 00:00:00
abstract：STUDY OBJECTIVES:To compare the efficacy of diclofenac sodium with ketorolac tromethamine in reducing postoperative morphine use after major orthopedic surgery. DESIGN:Double-blind, randomized, placebo-controlled study. SETTING:Major teaching institution. PATIENTS:102 ASA physical status II patients undergoing hip a...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(01)00382-8
更新日期：2002-05-01 00:00:00
abstract：:Vasoplegic syndrome (VS) is increasingly recognized as an important clinical entity in perioperative medicine. VS is characterized by significant arterial hypotension, normal or high cardiac output, low systemic vascular resistance, and increased requirements for intravenous volume and vasopressors. Tremendous variati...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,评审
doi：10.1016/j.jclinane.2017.04.017
更新日期：2017-08-01 00:00:00
abstract：:von Willebrand disease (VWD) is the most common hereditary bleeding disorder in humans, with an estimated prevalence of 0.5% to 1%. Patients with VWD are at increased risk of perioperative bleeding complications. This review provides an evidence-based overview of VWD and its management during the perioperative period....
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,评审
doi：10.1016/j.jclinane.2011.02.003
更新日期：2011-08-01 00:00:00
abstract：STUDY OBJECTIVE:To compare the intraoperative effects and recovery characteristics when either midazolam or propofol was used for sedation during local or regional anesthesia. DESIGN:Open-label, randomized study with blinded observer assessing recovery data. SETTING:Outpatients undergoing elective surgical procedures...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0952-8180(91)90203-y
更新日期：1991-01-01 00:00:00
