Prevention of central venous catheter-related bloodstream infections: is it time to add simulation training to the prevention bundle?

Abstract:

STUDY OBJECTIVE:To study the impact of adding simulation-based education to the pre-intervention mandatory hospital efforts aimed at decreasing central venous catheter-related blood stream infections (CRBSI) in intensive care units (ICU). DESIGN:Pre- and post-intervention retrospective observational investigation. SETTING:24-bed ICU and a 562-bed university-affiliated, urban teaching hospital. PATIENTS:ICU patients July 2004-June 2008 were studied for the development of central venous catheter related blood stream infections (CRBSI). MEASUREMENTS:ICU patients from July 2004-June 2008 were studied for the development of central venous catheter-related blood stream infections (CRBSI). PRE-INTERVENTION: mandatory staff and physician education began in 2004 to reduce CRBSI. The CRBSI-prevention program included online and didactic courses, and a pre- and post-test. Elements in the pre-intervention efforts included hand hygiene, full barrier precautions, use of Chlorhexidine skin preparation, and mask, gown, gloves, and hat protection for operators. A catheter-insertion cart containing all supplies and checklist were was a mandatory element of this program; a nurse was empowered to stop the procedure for non-performance of checklist items. INTERVENTION:As of July 1, 2006, a mandatory simulation-based program for all intern, resident, and fellow physicians was added to teach central venous catheter (CVC) insertion. MEASUREMENTS:Data collected pre- and post-intervention were CRBSI incidence, number of ICU catheter days, mortality, laboratory pathogen results, and costs. MAIN RESULTS:The pre-intervention CRBSI incidence of 6.47/1,000 catheter days was reduced significantly to 2.44/1,000 catheter days post-intervention (58%; P < 0.05), resulting in a $539,902 savings (USD; 47%), and was attributed to shorter ICU and hospital lengths of stay. CONCLUSIONS:Following simulation-based CVC program implementation, CRBSI incidence and costs were significantly reduced for two years post-intervention.

journal_name

J Clin Anesth

authors

Burden AR,Torjman MC,Dy GE,Jaffe JD,Littman JJ,Nawar F,Rajaram SS,Schorr C,Staman GW,Reboli AC

doi

10.1016/j.jclinane.2012.04.006

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

555-60

issue

7

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(12)00245-0

journal_volume

24

pub_type

杂志文章
  • Delayed awakening following inadvertent high-dose remifentanil infusion in a 13 year old patient.

    abstract::We report the case of a 13 year old patient who received 3.0 mg of remifentanil during a 50-minute surgical procedure as a result of a dosage miscalculation. The patient failed to awaken at the conclusion of the procedure and showed signs of opioid overdose. She recovered spontaneously two hours later. ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2010.07.005

    authors: Barak M,Greenberg Z,Danino J

    更新日期:2011-06-01 00:00:00

  • Leadership and management of academic anesthesiology departments in the United States.

    abstract:STUDY OBJECTIVE:To characterize the approach of academic chairs of anesthesiology in leading and managing their departments, and to gain insights into what they considered the most difficult challenges as chairs. DESIGN:Internet-based survey instrument conducted during July and August of 2006. SETTING:Academic medica...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2008.08.009

    authors: Mets B,Galford JA

    更新日期:2009-03-01 00:00:00

  • The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis.

    abstract:PURPOSE:The aim of this study was to evaluate the effect of neuraxial blocks on surgical blood losses and on the number of patients requiring blood transfusion. METHODS:A search of the American National Library of Medicine's PubMed up to November 12, 2004, was performed. Twenty-four studies could be kept for analysis....

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jclinane.2005.08.013

    authors: Guay J

    更新日期:2006-03-01 00:00:00

  • Major complications of regional anesthesia in 11 teaching hospitals of China: a prospective survey of 106,569 cases.

    abstract:STUDY OBJECTIVE:To determine the incidence of major complications in patients undergoing regional anesthesia (RA) in China. DESIGN:Multicenter prospective survey. SETTING:Eleven teaching hospitals in China. PATIENTS AND INTERVENTIONS:A total of 106,569 patients undergoing RA from April 1, 2009, to April 30, 2011, we...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jclinane.2016.01.022

    authors: Huo T,Sun L,Min S,Li W,Heng X,Tang L,Zhu S,Dong H,Wang Q,Xiong L

    更新日期:2016-06-01 00:00:00

  • Comparison of the morphine-sparing effects of diclofenac sodium and ketorolac tromethamine after major orthopedic surgery.

    abstract:STUDY OBJECTIVES:To compare the efficacy of diclofenac sodium with ketorolac tromethamine in reducing postoperative morphine use after major orthopedic surgery. DESIGN:Double-blind, randomized, placebo-controlled study. SETTING:Major teaching institution. PATIENTS:102 ASA physical status II patients undergoing hip a...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(01)00382-8

    authors: Alexander R,El-Moalem HE,Gan TJ

    更新日期:2002-05-01 00:00:00

  • Unusual etiology of hyperkalemia in an immunocompromised patient.

    abstract::Hyperkalemia was found in an immunocompromised patient undergoing emergency cystoscopy. The cause of the hyperkalemia was an intraperitoneal rupture of the bladder. This case report discusses conditions that predispose patients to bladder rupture and anesthetic management of hyperkalemia. ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/0952-8180(91)90095-5

    authors: Newland MC,Hosman SL,Newland JR,Landers DF

    更新日期:1991-11-01 00:00:00

  • Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer.

    abstract:STUDY OBJECTIVE AND DESIGN:The mechanism of action of commonly used general anesthetics is largely unknown. One hypothesized mechanism is through modulation of microtubule stability. Taxanes, a subset of chemotherapeutic drugs known to alter microtubule stability and commonly used to treat breast cancer, offer a natura...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2015.05.001

    authors: Linganna RE,Levy WJ,Dmochowski IJ,Eckenhoff RG,Speck RM

    更新日期:2015-09-01 00:00:00

  • Comparison of cisatracurium-induced neuromuscular blockade between immediate postpartum and nonpregnant patients.

    abstract:STUDY OBJECTIVES:To evaluate and compare cisatracurium-induced neuromuscular blockade and intubating conditions between immediate postpartum (PP) and nonpregnant (NP) patients. DESIGN:Prospective control study. SETTINGS:University Hospital Center. PATIENTS:44 ASA physical status I and II patients: 22 immediate postp...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0952-8180(01)00226-4

    authors: Pan PH,Moore C

    更新日期:2001-03-01 00:00:00

  • Carbetocin for prevention of postcesarean hemorrhage in women with severe preeclampsia: a before-after cohort comparison with oxytocin.

    abstract:STUDY OBJECTIVE:The aim of the study was to compare the incidence of the use of additional uterotonics before and after the change of carbetocin to oxytocin for the prevention of postpartum hemorrhage after cesarean delivery in women with severe preeclampsia. DESIGN:This was an observational retrospective before-and-a...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2016.08.017

    authors: Nucci B,Aya A,Aubry E,Ripart J

    更新日期:2016-12-01 00:00:00

  • Posterior reversible encephalopathy syndrome during pregnancy: seizures in a previously healthy parturient.

    abstract::Posterior reversible encephalopathy syndrome refers to a neuroradiologic disorder in which seizure activity (multiple seizures are more common than single events) is commonly the initial presenting symptom. We describe a case of posterior reversible encephalopathy syndrome in a previously healthy parturient who presen...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2006.07.004

    authors: Long TR,Hein BD,Brown MJ,Rydberg CH,Wass CT

    更新日期:2007-03-01 00:00:00

  • Pretreatment with sedative-hypnotics, but not with nondepolarizing muscle relaxants, attenuates alfentanil-induced muscle rigidity.

    abstract:STUDY OBJECTIVE:To evaluate and compare the efficacy of various pretreatment agents to attenuate or prevent opioid-induced muscle rigidity using a well-established, previously described clinical protocol. DESIGN:Prospective, controlled, single-blind, partially randomized study. SETTING:Large medical center. PATIENTS...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0952-8180(94)90087-6

    authors: Sanford TJ Jr,Weinger MB,Smith NT,Benthuysen JL,Head N,Silver H,Blasco TA

    更新日期:1994-11-01 00:00:00

  • Rocuronium infusion requirements and plasma concentrations at constant levels of neuromuscular paralysis during three phases of liver transplantation.

    abstract:STUDY OBJECTIVE:To develop a rapid online test of graft liver function during liver transplantation. DESIGN:Prospective, observational study. SETTING:University hospital transplant unit. PATIENTS:17 adult patients with end-stage liver disease who underwent liver transplantation surgery. INTERVENTIONS:Rocuronium inf...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0952-8180(03)00061-8

    authors: Gao L,Ramzan I,Baker B

    更新日期:2003-06-01 00:00:00

  • Chest ultrasonography in emergency Cesarean delivery in multi-valvular heart disease with pulmonary edema during spinal anesthesia.

    abstract::Valvular heart disease in a parturient presenting for Cesarean section is challenging. A 25 year old primigravida parturient with severe mitral stenosis, mild mitral regurgitation, mild aortic regurgitation, and mild pulmonary arterial hypertension required Cesarean delivery after developing pulmonary edema. Low-dose ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2013.12.009

    authors: Samanta S,Samanta S,Ghatak T,Grover VK

    更新日期:2014-05-01 00:00:00

  • The neurologic implications of diabetic hyperglycemia during surgical procedures at increased risk for brain ischemia.

    abstract::The neurologic implications of diabetic hyperglycemia depend on whether the ischemic insult is permanent or temporary. Laboratory studies show that following permanent focal ischemia, a situation analogous to stroke, diabetic hyperglycemia is protective in the penumbral region, whereas it may slightly increase infarct...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/s0952-8180(97)00021-4

    authors: Sieber FE

    更新日期:1997-06-01 00:00:00

  • Transversus abdominis plane block as a component of multimodal analgesia for laparoscopic cholecystectomy.

    abstract:OBJECTIVE:To evaluate and compare intercostal-iliac transversus abdominis plane (TAP) and oblique subcostal TAP (OSTAP) blocks for multimodal analgesia in patients receiving laparoscopic cholecystectomy. DESIGN:A prospective, randomized, double-blinded clinical study. SETTING:Operating room, postoperative recovery ar...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2016.03.033

    authors: Oksar M,Koyuncu O,Turhanoglu S,Temiz M,Oran MC

    更新日期:2016-11-01 00:00:00

  • Pooled analysis of three large clinical trials to determine the optimal dose of dolasetron mesylate needed to prevent postoperative nausea and vomiting. The Dolasetron Prophylaxis Study Group.

    abstract:STUDY OBJECTIVE:To identify the maximally effective dolasetron dose (i.e., maximum efficacy with minimum adverse events) for prevention of postoperative nausea and vomiting (PONV) using the statistical power generated in a pooled patient sample from three large, nearly identical clinical trials. DESIGN:Three randomize...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0952-8180(99)00123-3

    authors: Philip BK,McLeskey CH,Chelly JE,McKenzie R,Kovac AL,Diemunsch P,DuBois DM

    更新日期:2000-02-01 00:00:00

  • Subcutaneous targeted neuromodulation technique for the treatment of intractable chronic postthoracotomy pain.

    abstract::Subcutaneous targeted neuromodulation has been used successfully in chronic neuropathic pain. A 26 year-old patient with severe postthoracotomy pain and ipsilateral "wing scapula" due to intraoperative injury of the long thoracic nerve, is reported. Application of targeted neuromodulation resulted in immediate pain re...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2009.10.018

    authors: Theodosiadis P,Grosomanidis V,Samoladas E,Chalidis BE

    更新日期:2010-12-01 00:00:00

  • Standard clinical risk factors for difficult laryngoscopy are not independent predictors of intubation success with the GlideScope.

    abstract:STUDY OBJECTIVES:To determine whether the first-attempt tracheal intubation incidence using the GlideScope videolaryngoscope is higher in patients with predicted increased risk of difficult laryngoscopy, and to assess the ability of other a priori defined standard risk factors to predict first-attempt intubation succes...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2011.03.006

    authors: Díaz-Gómez JL,Satyapriya A,Satyapriya SV,Mascha EJ,Yang D,Krakovitz P,Mossad EB,Eikermann M,Doyle DJ

    更新日期:2011-12-01 00:00:00

  • Early increases in cardiac troponin levels after major vascular surgery is associated with an increased frequency of delayed cardiac complications.

    abstract:OBJECTIVE:To evaluate changes in cardiac troponin-I levels after major vascular surgery and their association with early and late postoperative cardiac complications. DESIGN:Prospective, observational investigation. SETTING:University teaching hospital. PATIENTS:75 consecutive patients undergoing major vascular surg...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jclinane.2005.11.005

    authors: Barbagallo M,Casati A,Spadini E,Bertolizio G,Kepgang L,Tecchio T,Salcuni P,Rolli A,Orlandelli E,Rossini E,Fanelli G

    更新日期:2006-06-01 00:00:00

  • Concurrent pericardial and pleural effusions: a double jeopardy.

    abstract::A 19-year-old man with large malignant pleural and pericardial effusions with tamponade physiology and signs of congestive heart failure presented for emergent subxiphoid pericardial window. Surgical drainage of the pericardium was complicated by a paradoxical cardiovascular collapse that failed to respond to pressors...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2016.04.056

    authors: Furst B,Liu CJ,Hansen P,Musuku SR

    更新日期:2016-09-01 00:00:00

  • Admixture of ephedrine to offset side effects of propofol: a randomized, controlled trial.

    abstract:STUDY OBJECTIVE:To determine whether adding ephedrine to propofol is as effective as adding lidocaine at reducing injection pain, and its effects on hemodynamics. DESIGN:Randomized, double-blinded, controlled trial. SETTING:District general hospital in the United Kingdom. PATIENTS:156 adult, ASA physical status I, I...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2008.06.018

    authors: Austin JD,Parke TJ

    更新日期:2009-02-01 00:00:00

  • Rocuronium versus succinylcholine-atracurium for tracheal intubation and maintenance relaxation during propofol anesthesia.

    abstract:STUDY OBJECTIVES:To compare the onset and offset time (clinical duration), and intubating conditions obtained with rocuronium bromide 0.6 mg/kg and succinylcholine 1.0 mg/kg after induction with propofol and fentanyl; and to compare rocuronium with atracurium for maintenance during propofol anesthesia. DESIGN:Prospect...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(00)00191-4

    authors: Lam AM,Pavlin EG,Visco E,Taraday J

    更新日期:2000-09-01 00:00:00

  • Intraocular pressure changes: the McGrath video laryngoscope vs the Macintosh laryngoscope; a randomized trial.

    abstract:STUDY OBJECTIVE:To determine the effects of the McGrath Series 5 video laryngoscope on intraocular pressure (IOP) during laryngoscopy. DESIGN:Prospective, randomized, double blind. SETTING:Operating room. PATIENTS:Eighty adult patients of American Society of Anesthesiologist physical status 1 scheduled for nonophtha...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2016.05.015

    authors: Karaman T,Dogru S,Karaman S,Demir S,Kaya Z,Suren M,Arici S,Kahveci M,Alim S

    更新日期:2016-11-01 00:00:00

  • Commercial propofol solutions: is the more expensive also the more effective?

    abstract:STUDY OBJECTIVE:To compare the efficacy and safety of four commercial propofol solutions marketed in Israel. DESIGN:Prospective, randomized, double-blind study. SETTING:University-affiliated medical center. PATIENTS:120 ASA physical status I and II nullipara patients undergoing dilatation and curettage for interrupt...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(01)00271-9

    authors: Weksler N,Rozentsveig V,Tarnoploski A,Gurman GM

    更新日期:2001-08-01 00:00:00

  • Posteromedial quadratus lumborum block versus transversus abdominal plane block for postoperative analgesia following laparoscopic colorectal surgery: A randomized controlled trial.

    abstract:STUDY OBJECTIVE:Our hypothesis was that a pre-operative posteromedial quadratus lumborum (QL) block would reduce postoperative morphine consumption and provide superior analgesia in the setting of multimodal analgesia compared with a lateral transversus abdominis plane (TAP) block for laparoscopic colorectal surgery. ...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2020.109716

    authors: Huang D,Song L,Li Y,Xu Z,Li X,Li C

    更新日期:2020-06-01 00:00:00

  • Alfentanil decreases the excitatory phenomena of sodium methohexital.

    abstract:STUDY OBJECTIVE:To evaluate the effects of alfentanil or lidocaine on the excitatory phenomena (myoclonus, cough, hiccough) caused by methohexital anesthesia and on the hemodynamic changes induced by retrobulbar block. DESIGN:Prospective, randomized, placebo-controlled, double-blind study. SETTING:University-affiliat...

    journal_title:Journal of clinical anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0952-8180(98)00072-5

    authors: Khalil SN,Howard G,Mankarious R,Campos C,Kellaway J,Chuang AZ,Ruiz R

    更新日期:1998-09-01 00:00:00

  • Management of airway in patients with laryngeal tumors.

    abstract:STUDY OBJECTIVE:To describe our systematic approach to securing the airway in patients with laryngeal tumors, developed over a 10-year period. DESIGN:Retrospective analysis. SETTING:University-affiliated veterans administration medical center. PATIENTS:Eight hundred one patients presenting for laryngeal tumor surger...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章

    doi:10.1016/j.jclinane.2004.12.019

    authors: Moorthy SS,Gupta S,Laurent B,Weisberger EC

    更新日期:2005-12-01 00:00:00

  • Remifentanil infusion during emergence moderates hemodynamic and cough responses to the tracheal tube: A randomized controlled trial.

    abstract:OBJECTIVE:To examine the severity of cough and straining at the time of emergence from anesthesia. DESIGN:Double-blind randomized, placebo-controlled study. SETTING:University-affiliated hospital. PATIENTS:Sixty-two American Society of Anesthesiologists 2 patients undergoing craniotomy and excision of supratentorial...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jclinane.2015.09.001

    authors: Ghodraty MR,Hasani V,Bagheri-Aghdam A,Zamani MM,Pournajafian A,Rokhtabnak F,Kholdebarin A,Nader ND

    更新日期:2016-09-01 00:00:00

  • Anesthetic management of the parturient with fever and infection.

    abstract::Fever is a common clinical problem in labor and delivery suites. It can result from a variety of infectious microorganisms, tissue trauma, malignancy, drug administration, and endocrine and immunologic disorders. Infection is the most common cause of fever, reflecting the effect of pyrogens on the hypothalamus. The di...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/s0952-8180(03)00081-3

    authors: Kuczkowski KM,Reisner LS

    更新日期:2003-09-01 00:00:00

  • The pharmacokinetics of remifentanil.

    abstract::Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects, even in patients with impaired cardiac function. With currently available opioids, precise titration of dose to effect is difficult, and high doses result in drug accumulatio...

    journal_title:Journal of clinical anesthesia

    pub_type: 杂志文章,评审

    doi:10.1016/s0952-8180(96)00179-1

    authors: Michelsen LG,Hug CC Jr

    更新日期:1996-12-01 00:00:00