Abstract:
STUDY OBJECTIVE:The aim of this 12-year case series was to review the drugs used during anesthetic management of patients with diagnosis of or risk criteria for Brugada syndrome (BrS), and to document any possible association between these drugs and arrhythmogenic activity or unexplained hemodynamic instability. DESIGN:A retrospective clinical observational study. SETTING:Tertiary hospital. PATIENTS:Thirty-one patients met our inclusion criteria: 20 belonging to group D (diagnosed BrS) and 11 to group R (risk of BrS). They underwent a total of 43 anesthetic interventions (28 in group D and 15 in group R). INTERVENTIONS:Records from patients with or at risk of BrS who underwent anesthetic intervention at our hospital between May 2003 and May 2015 were retrospectively reviewed. Drugs used were compared with those recommended to be avoided or preferably avoided, published by specialists in the field at brugadadrugs.org. MEASUREMENTS:Hemodynamic and cardiac complications during anesthesia were assessed for hypothetical association with these drugs. MAIN RESULTS:From the list of drugs available in medical literature recommended to avoid in BrS patients the following were used in our series: propofol (n = 8 in group D, n = 8 in group R), local anesthetics (n = 15 in group D, n = 8 in group R), tramadol (n = 1 in group D), and metoclopramide (n = 1 in group D). Hemodynamic complications occurred in 5 procedures, but no direct association was found between these events and the use of the drugs listed above. CONCLUSIONS:Major adverse events related to the deleterious effects of drugs recommended to be avoided were not detected in our series of patients with or at risk of BrS. Although authors cannot refute the theoretical risk of major adverse advents when using known or potential BrS triggers, the true clinical risk of these drugs is unknown, and recommendations to avoid their use should be better supported.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Duque M,Santos L,Ribeiro S,Catré Ddoi
10.1016/j.jclinane.2016.09.031subject
Has Abstractpub_date
2017-02-01 00:00:00pages
168-173eissn
0952-8180issn
1873-4529pii
S0952-8180(16)30913-8journal_volume
36pub_type
杂志文章abstract:STUDY OBJECTIVE:To evaluate the accuracy and precision of estimation of partial pressure of carbon dioxide (Pa(CO2)) using end-tidal or transcutaneous CO2 (TcP(CO2)) measurements during mechanical ventilation in the elderly patient. DESIGN:A prospective, observational study was conducted. SETTINGS:The study was done ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2006.02.007
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To evaluate changes in cardiac troponin-I levels after major vascular surgery and their association with early and late postoperative cardiac complications. DESIGN:Prospective, observational investigation. SETTING:University teaching hospital. PATIENTS:75 consecutive patients undergoing major vascular surg...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/j.jclinane.2005.11.005
更新日期:2006-06-01 00:00:00
abstract::"A professor is a gentleman with a different point of view." This characteristic and sarcastic statement was often recited by August Bier (1861-1949) and can also be aptly applied to him. As the father of spinal and intravenous regional neural blockade, Bier had a tremendous impact on surgery and anesthesia. It took h...
journal_title:Journal of clinical anesthesia
pub_type: 传,历史文章,杂志文章
doi:10.1016/s0952-8180(00)00202-6
更新日期:2000-11-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the postoperative analgesia of three different concentrations of levobupivacaine for ilioinguinal/iliohypogastric (II/IH) block in children undergoing inguinal hernia repair. DESIGN:Double-blind, prospective, randomized, controlled trial. SETTING:Operating room and postoperative recovery ar...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2008.10.012
更新日期:2009-09-01 00:00:00
abstract:STUDY OBJECTIVE:Our hypothesis was that a pre-operative posteromedial quadratus lumborum (QL) block would reduce postoperative morphine consumption and provide superior analgesia in the setting of multimodal analgesia compared with a lateral transversus abdominis plane (TAP) block for laparoscopic colorectal surgery. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2020.109716
更新日期:2020-06-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the reliability of assessments of nasal flow rate for improved nostril selection for nasotracheal intubation. DESIGN:Prospective, randomized, double-blinded study. SETTING:Operating room of a university-affiliated hospital. PATIENTS:118 ASA physical status 1 and 2 patients, aged 18-65 yea...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2011.08.006
更新日期:2012-06-01 00:00:00
abstract::The right heart and great veins can be the harbinger of septic and aseptic thromboemboli, which can result in a spectrum of clinical syndromes. This report presents five distinct clinical scenarios of thromboembolization, the occurrence of which in the central circulation resulted in life-threatening sepsis and hemody...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/0952-8180(93)90071-l
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To evaluate and compare the face mask (FM) and oral mask (OM) ventilation techniques during anesthesia emergence regarding tidal volume, leak volume, and difficult mask ventilation (DMV) incidence. DESIGN:Prospective, randomized, crossover study. SETTING:Operating room, training and research hospital. SUBJ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2015.12.008
更新日期:2016-06-01 00:00:00
abstract::Neuromuscular blocking agents are used in many surgical procedures and have enabled new surgical advances. The expanded landscape of neuromuscular blockade (NMB) reversal drugs allows for fast and complete NMB reversal and the reduction of postoperative complications from residual block. In the United States, neostigm...
journal_title:Journal of clinical anesthesia
pub_type: 信件
doi:10.1016/j.jclinane.2017.07.004
更新日期:2017-11-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate the effects of intravenous (IV) versus oral clonidine on alterations of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and plasma-catecholamines due to endotracheal intubation. DESIGN:Randomized, double-blind, placebo-controlled study. SETTING:University hospital su...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/S0952-8180(97)00239-0
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Strabismus surgery is perhaps a pediatric surgical procedure that has the strongest evidence of postoperative nausea and vomiting (PONV) risk. This randomized controlled blind study was designed to evaluate the efficacy of combined therapy of dexamethasone and intraoperative superhydration vs their monothera...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2016.03.049
更新日期:2016-11-01 00:00:00
abstract:STUDY OBJECTIVE:An estimated 80% of older people undergoing surgery develop postoperative delirium (POD) making them a high-risk group. Research in this area is growing fast but there is no established consensus on strategies for POD prevention or management. A systematic review and meta-analysis were conducted to synt...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/j.jclinane.2020.110004
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hybrid operating room suites with intraoperative magnetic resonance imaging enable image guided surgery in a fully functional operating room environment. While this environment creates challenges to anesthetic care, the effects on anesthetic adverse events and outcomes are largely unknown. This...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2018.10.022
更新日期:2019-05-01 00:00:00
abstract::During transplant surgery, clot formation resulting in life-threatening thromboembolic phenomena or graft loss may be a consequence unless close monitoring of coagulation and anticoagulation treatment is instituted in a timely manner. Three cases with a hypercoagulable state, as determined by thrombelastography at the...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2009.10.021
更新日期:2011-02-01 00:00:00
abstract::A 53-year-old healthy man underwent elective laparoscopic, extraperitoneal, right-sided herniorrhaphy. Postoperatively, he complained of chest pain on inspiration. Chest x-ray and computed tomographic scan revealed a pneumomediastinum and a right-sided pneumothorax. Previous case reports and possible etiologies are re...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/j.jclinane.2004.05.009
更新日期:2005-05-01 00:00:00
abstract::We report an interaction of a transesophageal atrial pacemaker (TAP) with a permanently implanted pacemaker in a cardiac patient who had undergone ablative therapy for atrial tachyarrhythmia 5 years earlier. The patient's permanent A-V pacemaker was completely inhibited by the TAP, and there was loss of ventricular co...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(99)00107-5
更新日期:1999-12-01 00:00:00
abstract::Transurethral vaporization of the prostate is a new method of electrosurgery used for treating benign prostatic hypertrophy. We observed simultaneous obturator nerve stimulation during spinal anesthesia while the middle lobe of the prostate was being resected. A discussion of why electrovaporization is different from ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(98)00069-5
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:When dexmedetomidine is used in patients undergoing spinal anesthesia, high incidence of bradycardia in response to parasympathetic activation is reported. Therefore, we aimed to evaluate the effectiveness of atropine premedication for preventing the incidence of bradycardia and the hemodynamic effect on pati...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2016.07.012
更新日期:2016-12-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the hemodynamic effects of two different concentrations of pentastarch hydroxyethyl starch (HES; 200/0.5) solutions with a 4% human albumin solution for fluid resuscitation. DESIGN:Open-label, randomized, controlled study. SETTING:Medical-surgical intensive care unit. PATIENTS:34 consecuti...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2008.05.022
更新日期:2008-11-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effects of the McGrath Series 5 video laryngoscope on intraocular pressure (IOP) during laryngoscopy. DESIGN:Prospective, randomized, double blind. SETTING:Operating room. PATIENTS:Eighty adult patients of American Society of Anesthesiologist physical status 1 scheduled for nonophtha...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2016.05.015
更新日期:2016-11-01 00:00:00
abstract:STUDY OBJECTIVE:Breast cancer is the most common malignancy of women all over the world. In this study, we compared the effects of ultrasound-guided modified pectoral nerve (PECS) block and erector spinae plane (ESP) block on postoperative opioid consumption, pain scores, and intraoperative fentanyl need of patients un...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2018.10.040
更新日期:2019-05-01 00:00:00
abstract::A 14 month old, 19 kg female infant with aminotic band syndrome and severe craniofacial malformations presented for placement of an open gastrostomy tube. Spontaneous ventilation was maintained while an "awake look" was performed with the video laryngoscope using intravenous propofol (30 mg total) for sedation. A Grad...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2011.07.004
更新日期:2012-03-01 00:00:00
abstract:STUDY OBJECTIVE:To examine perioperative management and complications in patients undergoing pneumonectomy. DESIGN:Observational cohort study. SETTING:University-affiliated city hospital. MEASUREMENTS:65 patients who underwent unilateral pneumonectomy for resection of lung cancer between March 1997 and October 2007 ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2009.02.013
更新日期:2010-02-01 00:00:00
abstract::Carditis can complicate Lyme disease in an estimated <5% of cases, and cardiogenic shock and severe cardiac arrhythmias are described with electrocardiographic abnormalities that could be suggestive of coronary manifestations. We report a case of severe persistent biventricular heart failure complicated by cardiac arr...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2016.08.005
更新日期:2016-12-01 00:00:00
abstract::Visualization of thromboembolic material in the pulmonary artery is often difficult on transesophageal echocardiography, especially in the left pulmonary artery, because of the position of the left main bronchus. We present a case in which thromboembolic material within the midleft pulmonary artery was incidentally di...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2007.06.026
更新日期:2008-03-01 00:00:00
abstract::This case describes a postoperative complication after single-lung ventilation in a 10-year-old patient scheduled for scoliosis repair. This patient underwent an anterior thoracoscopic excision of several vertebral discs followed by a posterior double-rod fixation of her spine. The postoperative course was complicated...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(02)00482-8
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Postoperative residual neuromuscular blockade (RNMB) is a common complication in the postanesthesia care unit (PACU), but also one of the most controversial issues. Many studies and trials demonstrated that some methods and techniques can reduce the incidence and the extent of the phenomenon. STUDY OBJECTIV...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2016.07.031
更新日期:2016-12-01 00:00:00
abstract:STUDY OBJECTIVE:Some outpatient procedures are performed under sedation with dexmedetomidine, although the effect of dexmedetomidine on cognitive function remains unclear. This study investigated the effect of dexmedetomidine on cognitive function in healthy volunteers. DESIGN:Observation study in volunteers. SETTING...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2016.03.017
更新日期:2016-09-01 00:00:00
abstract:STUDY OBJECTIVES:To evaluate the efficacy and safety of granisetron-droperidol combination for the prevention of postoperative nausea and vomiting (PONV) after middle ear surgery. DESIGN:Prospective, randomized, double-blind study. SETTING:University hospital. PATIENTS:150 ASA physical status I patients (108 females...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验,收录出版
doi:10.1016/s0952-8180(99)00011-2
更新日期:1999-03-01 00:00:00
abstract::Brugada syndrome is an electrical cardiac disease predisposing to ventricular arrhythmias in which typical electrocardiographic (ECG) features consist of nonischemic repolarization abnormalities in the right precordial leads V1-V3. The appearance of a Brugada-ECG pattern is increasingly observed in critically ill pati...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2013.02.012
更新日期:2013-09-01 00:00:00