Abstract：
:We presented a proposed neural level mechanism for the integration of cognitive and affective information during covert decision making. The central idea is that the ventromedial prefrontal cortex establishes predicted outcomes of responses through its connections with the amygdala, and that this information is passed through the context-moderated gateway in the nucleus accumbens in order to promote behaviours that are most beneficial to the long term survival of the organism. We then implemented the proposed mechanism in a network of spiking neurons, and tested one of its central claims. Results showed that the model was capable of producing behaviour similar to that observed in normal humans, as well as that exhibited during VMPFC damage.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Wagar BM,Thagard Pdoi
10.1016/s0278-2626(03)00153-2subject
Has Abstractpub_date
2003-11-01 00:00:00pages
398-402issue
2eissn
0278-2626issn
1090-2147pii
S0278262603001532journal_volume
53pub_type
杂志文章abstract：:Deficits in working memory have been shown to contribute to poor performance on the Iowa Gambling Task [IGT: Bechara, A., & Martin, E.M. (2004). Impaired decision making related to working memory deficits in individuals with substance addictions. Neuropsychology, 18, 152-162]. Similarly, a secondary memory load task h...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2007.05.006
更新日期：2008-02-01 00:00:00
abstract：:Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Although a variety of behavioral studies have provided stro...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.06.009
更新日期：2009-12-01 00:00:00
abstract：:Declines in verbal fluency are consistently reported in patients with Parkinson's disease (PD) after pallidal surgery. In the present study, the clustering and switching components of semantic or category fluency (oral naming of items obtainable in supermarkets) were examined at baseline and four months after unilater...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/s0278-2626(02)00504-3
更新日期：2002-11-01 00:00:00
abstract：:Compassion is considered a moral emotion related to the perception of suffering in others, and resulting in a motivation to alleviate the afflicted party. We compared brain correlates of compassion-evoking images in women and men. BOLD functional images of 24 healthy volunteers (twelve women and twelve men; age=27±2.5...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2011.03.019
更新日期：2011-06-01 00:00:00
abstract：:Response time studies of acquired language disorders are plagued by tremendous variability in patients' response times. In this brief report we demonstrate how variability itself may provide informative data. Lexical decision response times, generated by nine patients, illustrate how within-patient variability may est...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:The voice is a marker of a person's identity which allows individual recognition even if the person is not in sight. Listening to a voice also affords inferences about the speaker's emotional state. Both these types of personal information are encoded in characteristic acoustic feature patterns analyzed within the aud...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2008.06.003
更新日期：2009-02-01 00:00:00
abstract：:The purpose of this study was to determine whether the severity of visual hemineglect follows a unimodal or bimodal frequency distribution. Seventy-seven consecutive patients with a unilateral cerebral infarct (36 left- and 41 right-hemisphere lesions) were evaluated. The severity of neglect was measured as the number...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1993.1010
更新日期：1993-03-01 00:00:00
abstract：:In this article we report the results of a test of the hypothesis that a form of attention/information processing dysfunction, attentional set impairment, is exacerbated by facial-oral tardive dyskinesia in schizophrenics. This hypothesis was tested in the context of a study that was aimed at determining whether the R...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1993.1042
更新日期：1993-09-01 00:00:00
abstract：:We investigated the consequences of premature birth on the functional neuroanatomy of the dorsal stream of visual processing. fMRI was recorded while sixteen healthy participants, 8 (two men) adults (19 years 6 months old, SD 10 months) born premature (mean gestational age 30 weeks), referred to as Premas, and 8 (two ...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2012.10.006
更新日期：2013-02-01 00:00:00
abstract：:This study investigated preparatory processes involved in adapting to changing episodic memory retrieval demands. Event-related potentials (ERPs) were recorded while participants performed a general old/new recognition task and a specific task that also required retrieval of perceptual details. The relevant task remai...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.01.004
更新日期：2009-06-01 00:00:00
abstract：:There is currently much interest in investigating the neural substrates of metaphor processing. In particular, it has been suggested that the right hemisphere plays a special role in the comprehension of figurative (non-literal) language, and in particular metaphors. However, some studies find no evidence of right hem...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.06.001
更新日期：2009-12-01 00:00:00
abstract：:We hypothesized that facial attractiveness represents a dual judgment, a combination of reward-based, sexual processes, and aesthetic, cognitive processes. Herein we describe a study that demonstrates that sexual and nonsexual processes both contribute to attractiveness judgments and that these processes can be dissoc...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.10.002
更新日期：2010-03-01 00:00:00
abstract：:The roles of speed of processing, inhibition, and presentation order in the Trail Making Test (TMT) performance were examined. One-hundred ten undergraduates performed the TMT (1/2 received order Part A-Part B, 1/2 received order Part B-Part A) and also completed computerized tests of inhibitory functioning and speed ...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1998.1034
更新日期：1998-11-01 00:00:00
abstract：:Our analysis of Medical College Admission Test subtest scores by writing hand preference and sex suggests that (a) right hemispheric dominance is associated with intellectual giftedness in verbal reasoning (left-handers obtained higher scores on the verbal reasoning test and were overrepresented in the upper tail of t...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1998.1021
更新日期：1998-10-01 00:00:00
abstract：:Two experiments are presented which investigated claims of asymmetrical transfer of training between the hands/hemispheres. In Experiment 1, 96 right- and left-handed male undergraduates practiced an inverted-reversed printing task with either the right or the left hand. Transfer to the opposite hand was then compared...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/0278-2626(89)90008-0
更新日期：1989-09-01 00:00:00
abstract：:This is a longitudinal study of facial expression of affect in 28 children with intractable infantile spasms who underwent epilepsy surgery. After a mean follow-up period of 1.8 years, there was a significant increase in positive affect, a significant decrease in neutral affect, and no change in negative affect during...
journal_title：Brain and cognition
pub_type： 临床试验,杂志文章
doi：10.1006/brcg.1998.1064
更新日期：1999-03-01 00:00:00
abstract：:How does the brain cause positive affective reactions to sensory pleasure? An answer to pleasure causation requires knowing not only which brain systems are activated by pleasant stimuli, but also which systems actually cause their positive affective properties. This paper focuses on brain causation of behavioral posi...
journal_title：Brain and cognition
pub_type： 杂志文章,评审
doi：10.1016/s0278-2626(03)00014-9
更新日期：2003-06-01 00:00:00
abstract：:Performance-based measures of hand preference have been developed as an objective method of examining handedness. Previous research using this method showed that both skill demands and the position of the object in working space affect preferential hand reaching. Specifically, preferred hand reaches predominated in le...
journal_title：Brain and cognition
pub_type： 临床试验,杂志文章
doi：10.1016/j.bandc.2004.02.041
更新日期：2004-07-01 00:00:00
abstract：:Many studies have shown that infants prefer infant-directed (ID) speech to adult-directed (AD) speech. ID speech functions to aid language learning, obtain and/or maintain an infant's attention, and create emotional communication between the infant and caregiver. We examined psychophysiological responses to ID speech ...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2007.02.008
更新日期：2007-10-01 00:00:00
abstract：:Semantic dementia (SD) is a progressive condition characterized by an insidious and gradual breakdown in semantic knowledge. Patients suffering from this condition gradually lose their knowledge of objects and their attributes, concepts, famous persons, and public events. In contrast, these patients maintain a strikin...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2004.02.034
更新日期：2004-07-01 00:00:00
abstract：:A preliminary electroencephalographic (EEG) investigation was conducted to determine if the pattern of hemispheric activation in mathematically precocious youth differs from that of average math ability subjects. Alpha activity at four brain sites (frontal, temporal, parietal, and occipital lobes) over the left and ri...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/0278-2626(91)90073-h
更新日期：1991-11-01 00:00:00
abstract：:Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained tasks. This random...
journal_title：Brain and cognition
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bandc.2020.105552
更新日期：2020-06-01 00:00:00
abstract：:When we observe a movement and then reproduce it, how is this visual input transformed into motor output? Studies on stroke patients with apraxia suggest that there may be two distinct routes used for gesture imitation; an indirect route that recruits stored movement memories (motor programs) and a direct route that b...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.04.008
更新日期：2009-11-01 00:00:00
abstract：:A controversial concept suggests that impaired finger dexterity in Parkinson's disease may be related to limb kinetic apraxia that is not explained by elemental motor deficits such as bradykinesia. To explore the nature of dexterous difficulties, the aim of the present study was to assess the relationship of finger de...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2011.06.003
更新日期：2011-10-01 00:00:00
abstract：:Observers classified sine-wave and square-wave gratings on the basis of fundamental frequency (Are the bars wide or narrow?) or on the basis of higher harmonic frequencies (Are the bars sharp or fuzzy?). Stimuli were presented in either the left (LVF) or right (RVF) visual field. When the classification was made on th...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/0278-2626(92)90023-f
更新日期：1992-11-01 00:00:00
abstract：:The manipulation of voice onset time (VOT) during dichotic listening has provided novel insights regarding brain function. To date, the most common design is the utilisation of four VOT conditions: short-long pairs (SL), where a CV syllable with a short VOT is presented to the left ear and a CV syllable with a long VO...
journal_title：Brain and cognition
pub_type： 杂志文章,评审
doi：10.1016/j.bandc.2011.01.007
更新日期：2011-07-01 00:00:00
abstract：:The concurrent-task method was used to investigate the hemispheric locus of face encoding. In each of three experiments, 48 right-handed adults performed unimanual finger tapping while encoding whole or partial faces for subsequent recognition. Faces were upright in Experiments 1 and 2 but inverted in Experiment 3. Ir...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1995.1162
更新日期：1995-07-01 00:00:00
abstract：:Individuals who carry a premutation (PM) allele on the FMR1 gene may experience executive limitations associated with their genetic status, including inhibition deficits. However, poor understanding of individualized risk factors has limited clinical management of this group, particularly in mothers who carry the PM a...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2019.105511
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Diffusion tensor imaging (DTI) has revealed microstructural aspects of adolescent brain development, the cognitive correlates of which remain relatively uncharacterized. METHODS:DTI was used to assess white matter microstructure in 18 typically developing adolescents (ages 16-18). Fractional anisotropy (FA)...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2008.01.009
更新日期：2008-07-01 00:00:00
abstract：:Recent work has demonstrated that horizontal saccadic eye movements enhance verbal episodic memory retrieval, particularly in strongly right-handed individuals. The present experiments test three primary assumptions derived from this research. First, horizontal eye movements should facilitate episodic memory for both ...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.03.003
更新日期：2009-08-01 00:00:00
