Abstract:
:Declines in verbal fluency are consistently reported in patients with Parkinson's disease (PD) after pallidal surgery. In the present study, the clustering and switching components of semantic or category fluency (oral naming of items obtainable in supermarkets) were examined at baseline and four months after unilateral deep brain stimulation or pallidotomy in 45 patients with PD (30 left, 15 right pallidal surgery). Post-operative declines were observed for supermarket fluency total score and switching, but not for average cluster size. These findings support the proposal that semantic fluency decrements after pallidal surgery reflect a disruption of frontal-basal ganglia circuits mediating efficient shifting between semantic categories, or perhaps efficient access to categories, rather than a degradation of semantic stores.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Tröster AI,Woods SP,Fields JA,Hanisch C,Beatty WWdoi
10.1016/s0278-2626(02)00504-3subject
Has Abstractpub_date
2002-11-01 00:00:00pages
207-17issue
2eissn
0278-2626issn
1090-2147pii
S0278262602005043journal_volume
50pub_type
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pub_type: 杂志文章
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journal_title:Brain and cognition
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journal_title:Brain and cognition
pub_type: 杂志文章
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pub_type: 杂志文章
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