Genomic structure and expression of the human fau gene: encoding the ribosomal protein S30 fused to a ubiquitin-like protein.

Abstract:

:The fau gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV). This virus acquired the fau sequence in its reversed transcriptional orientation. Human and mouse fau cDNA's were identified and both encode a new protein of 133 AA. We show that fau (for FBR-MuSV associated ubiquitiously expressed gene) becomes expressed in all different tissues tested as a 600 bp messenger and we report the genomic structure of the human fau gene. The gene consists of five exons and four introns and the 5' untranslated region displays characteristic features for a housekeeping gene. Fau encodes the ribosomal protein S30 fused to a Ubiquitin-like protein.

authors

Kas K,Michiels L,Merregaert J

doi

10.1016/0006-291x(92)91286-y

subject

Has Abstract

pub_date

1992-09-16 00:00:00

pages

927-33

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(92)91286-Y

journal_volume

187

pub_type

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