Reversibility of cardiac abnormalities in adolescents with anorexia nervosa after weight recovery.

Abstract:

OBJECTIVE:Anorexia nervosa is a life-threatening condition, with significant risk for death due to cardiac complications. The objective of this study was to analyze the cardiac involvement in anorexia nervosa and to study the reversibility of cardiac abnormalities. METHOD:Thirty-one consecutive adolescents (aged 12 to 17 years) with a diagnosis of anorexia nervosa were evaluated from January 1998 to January 1999 at the Hospital Clínic (University of Barcelona, Catalonia, Spain). An electrocardiogram, an echocardiogram, a 24-hour Holter recording with heart rate variability, an exercise test, and a tilt test were performed at initial examination and after refeeding (3 to 18 months later). RESULTS:The basal body mass index was 15.2 +/- 2 kg/m2. Sinus bradycardia was found in 35% of patients, 93% showed a decreased left ventricular mass, and 70% had a diminished thickness of cardiac walls. The Holter recordings showed nocturnal bradycardia in 60% with an increased heart rate variability. After refeeding, a significant decrease in QT interval (p <.05) and QT dispersion (p <.01) was observed. Echocardiograms showed an increase in cardiac diameters (p <.01), left ventricular mass (p <.001), and cardiac output (p <.001). There was also an improvement in the exercise capacity (p <.05) and a normalization of the heart rate and heart rate variability (p <.05). CONCLUSION:Cardiac structural and functional abnormalities provoked by anorexia nervosa are reversible in young adolescents after refeeding.

authors

Mont L,Castro J,Herreros B,Paré C,Azqueta M,Magriña J,Puig J,Toro J,Brugada J

doi

10.1097/01.CHI.0000046867.56865.EB

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

808-13

issue

7

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)60980-1

journal_volume

42

pub_type

杂志文章
  • Temperament and stress resilience in school-age children: a within-families study.

    abstract:OBJECTIVE:Stress resilience was assessed in 81 school-age children, from within 32 families acknowledging severe psychosocial stress. Resilient and nonresilient children, identified via competence and behavior disorder measures from school and home, were compared. METHOD:Parents and teachers completed questionnaires a...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199502000-00012

    authors: Smith J,Prior M

    更新日期:1995-02-01 00:00:00

  • Prenatal smoking and internalizing and externalizing problems in children studied from childhood to late adolescence.

    abstract:OBJECTIVE:To study whether prenatal smoking only relates to externalizing problems or whether it is associated with both internalizing and externalizing problems from childhood into late adolescence. METHOD:Child Behavior Checklist-derived, parent-reported internalizing and externalizing problems of 396 children were ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/CHI.0b013e318172eefb

    authors: Ashford J,van Lier PA,Timmermans M,Cuijpers P,Koot HM

    更新日期:2008-07-01 00:00:00

  • The clinical utility of the proposed DSM-5 callous-unemotional subtype of conduct disorder in young girls.

    abstract:OBJECTIVE:A callous-unemotional (CU) subtype of conduct disorder (CD) has been proposed as an addition to the fifth edition of the Diagnostic and Statistic Manual of Mental Disorders (DSM-5). This study tested the hypothesis that young girls with the CU subtype of CD would exhibit more severe antisocial behavior and le...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.jaac.2011.10.005

    authors: Pardini D,Stepp S,Hipwell A,Stouthamer-Loeber M,Loeber R

    更新日期:2012-01-01 00:00:00

  • Maternal depression and warmth during childhood predict age 20 neural response to reward.

    abstract:OBJECTIVE:Early parenting experiences likely shape children's brain development, with consequences potentially extending into adulthood. Parents' affective disorders and expressions of positive affect could exert an influence on affect-related circuitry. The current study evaluated how maternal depression and maternal ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.jaac.2013.10.003

    authors: Morgan JK,Shaw DS,Forbes EE

    更新日期:2014-01-01 00:00:00

  • Maternal characteristics and perceptions of pervasive and situational hyperactives and normal controls.

    abstract::Thirty 6- to 9-year-old boys were rated by their mothers and teachers as being pervasively hyperactive, situationally hyperactive, or not hyperactive at home or school. Maternal characteristics and perceptions of their children's behavior problems were collected. Children's global and molecular social skills were also...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199007000-00008

    authors: Beck SJ,Young GH,Tarnowski KJ

    更新日期:1990-07-01 00:00:00

  • Case study: two additional sudden deaths with tricyclic antidepressants.

    abstract::Since 1990, there have been five reported cases of sudden death in children treated with desipramine. This case study describes the sudden deaths of two additional children treated with tricyclic antidepressants, one with desipramine, 3.3 mg/kg per day, the other with imipramine, 6 mg/kg per day and thioridazine, 1 mg...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199703000-00018

    authors: Varley CK,McClellan J

    更新日期:1997-03-01 00:00:00

  • Obsessive-compulsive disorder in children and adolescents: a review of the past 10 years.

    abstract:OBJECTIVE:To review the literature on pediatric obsessive-compulsive disorder (OCD) from the perspective of information relevant to American Board of Psychiatry and Neurology recertification in child and adolescent psychiatry. METHOD:The clinical and research literatures were systematically searched or articles that a...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/00004583-199610000-00012

    authors: March JS,Leonard HL

    更新日期:1996-10-01 00:00:00

  • Psychopathology in parents of depressed children and adolescents.

    abstract::One hundred and seventeen biological mothers and 63 biological fathers of depressed and nondepressed, psychiatrically disturbed children and adolescents were interviewed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version. Diagnostic information was also obtained on 54 biological fathers who w...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-198905000-00008

    authors: Mitchell J,McCauley E,Burke P,Calderon R,Schloredt K

    更新日期:1989-05-01 00:00:00

  • Predicting child PTSD: the relationship between acute stress disorder and PTSD in injured children.

    abstract:OBJECTIVE:To examine the prevalence of acute stress disorder (ASD) and posttraumatic stress disorder (PTSD) in injured children and to evaluate the utility of ASD as a predictor of PTSD. METHOD:Children hospitalized for injuries sustained in a traffic crash were enrolled in a prospective study. ASD was assessed in 243...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-200404000-00006

    authors: Kassam-Adams N,Winston FK

    更新日期:2004-04-01 00:00:00

  • Genetic latent structure analysis of dysmorphology in attention deficit disorder.

    abstract::Dysmorphology--in the form of minor physical anomalies--has been frequently reported in children with attention deficit disorder (ADD). The authors report an overrepresentation of minor physical anomalies in both ADD probands and their first-degree relatives. Further, ADD probands who are not dysmorphic have non-ADD r...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199003000-00006

    authors: Deutsch CK,Matthysse S,Swanson JM,Farkas LG

    更新日期:1990-03-01 00:00:00

  • Personality predictors of outcome for adolescents hospitalized for suicidal ideation.

    abstract:OBJECTIVE:Recent cross-sectional studies of adolescents have noted an association between the personality traits of perfectionism and self-criticism and suicidal ideation. The present study was undertaken to examine the relationship between personality dimensions and the outcome of treatment of adolescents hospitalized...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/01.CHI.0000046847.56865.B0

    authors: Enns MW,Cox BJ,Inayatulla M

    更新日期:2003-06-01 00:00:00

  • Prevalence of mental disorder in military children and adolescents: findings from a two-stage community survey.

    abstract:OBJECTIVE:Because previous reports have suggested that children of military families are at greater risk for psychopathology, this study examines the levels of psychopathology in an epidemiological community sample of military children all living on a military post. METHOD:Standardized psychopathology rating scales an...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004583-199511000-00019

    authors: Jensen PS,Watanabe HK,Richters JE,Cortes R,Roper M,Liu S

    更新日期:1995-11-01 00:00:00

  • Children's Interview for Psychiatric Syndromes (ChIPS).

    abstract:OBJECTIVE:To describe the development and summarize the psychometric properties of the Children's Interview for Psychiatric Syndromes (ChIPS). METHOD:ChIPS is a highly structured interview designed for use by trained lay interviewers in children aged 6-18 years. It screens for 20 Axis I disorders as well as psychosoci...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-200001000-00019

    authors: Weller EB,Weller RA,Fristad MA,Rooney MT,Schecter J

    更新日期:2000-01-01 00:00:00

  • Effects of emotion on perceptual asymmetry in adolescent inpatients with attention-deficit hyperactivity disorder.

    abstract:OBJECTIVE:The authors studied the hemispheric functioning of adolescents with attention-deficit hyperactivity disorder (ADHD) in relation to this group's response to positively toned emotional stimuli. METHOD:Dichotic word tests were used to measure perceptual asymmetry in 21 adolescent inpatients and 24 control subje...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199303000-00012

    authors: Becker DF,Doane JA,Wexler BE

    更新日期:1993-03-01 00:00:00

  • Psychopathology and health care use among preschool children: a retrospective analysis.

    abstract:OBJECTIVE:To examine the relationship between psychopathology and health care utilization beginning in the preschool (ages 2 to 5) years. METHOD:Five hundred ten preschool children were enrolled through 68 primary care physicians. The test battery used for diagnoses included the Child Behavior Checklist, a development...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199803000-00010

    authors: Lavigne JV,Binns HJ,Arend R,Rosenbaum D,Christoffel KK,Hayford JR,Gibbons RD

    更新日期:1998-03-01 00:00:00

  • Identity, Conformity, and Nonconformity: A Closer Look.

    abstract::As clinicians, we have been vigilant to screen for underlying psychopathology in children and adolescents who meet criteria for gender dysphoria (GD) based on the risk these individuals have for developing externalizing and/or internalizing disorders, likely driven by a stigmatizing society. However, we have not paid ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 评论,社论

    doi:10.1016/j.jaac.2018.05.001

    authors: Daniolos PT

    更新日期:2018-07-01 00:00:00

  • The effects of a multimodal intervention with attention-deficit hyperactivity disorder children: a 9-month follow-up.

    abstract::Using a double-blind, placebo design, we evaluated 96 attention-deficit hyperactivity disordered children for the effects of methylphenidate alone and in combination with behavioral parent training plus child self-control instruction. Seventy one of the children completed the treatment protocol. As reported previously...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004583-199301000-00026

    authors: Ialongo NS,Horn WF,Pascoe JM,Greenberg G,Packard T,Lopez M,Wagner A,Puttler L

    更新日期:1993-01-01 00:00:00

  • The impact of case definition on attention-deficit/hyperactivity disorder prevalence estimates in community-based samples of school-aged children.

    abstract:OBJECTIVE:To determine the impact of varying attention-deficit/hyperactivity disorder (ADHD) diagnostic criteria, including new DSM-5 criteria, on prevalence estimates. METHOD:Parent and teacher reports identified high- and low-screen children with ADHD from elementary schools in 2 states that produced a diverse overa...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.jaac.2014.10.014

    authors: McKeown RE,Holbrook JR,Danielson ML,Cuffe SP,Wolraich ML,Visser SN

    更新日期:2015-01-01 00:00:00

  • Clomipramine in autism: preliminary evidence of efficacy.

    abstract::This report provides preliminary evidence for the efficacy of clomipramine in the treatment of young adults with autistic disorder. Four of five outpatients with autistic disorder showed significant improvement in social relatedness, obsessive compulsive symptoms, and aggressive and impulsive behavior with clomipramin...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199207000-00025

    authors: McDougle CJ,Price LH,Volkmar FR,Goodman WK,Ward-O'Brien D,Nielsen J,Bregman J,Cohen DJ

    更新日期:1992-07-01 00:00:00

  • Short-term outcome of major depression: I. Comorbidity and severity at presentation as predictors of persistent disorder.

    abstract:OBJECTIVE:To determine whether there is a pattern of clinical characteristics at presentation that specifically predicts persistent major depression at 36 weeks follow-up. METHOD:Sixty-eight consecutive cases with a first episode DSM-III-R diagnosis of major depression were interviewed with the Schedule for Affective ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199702000-00008

    authors: Goodyer IM,Herbert J,Secher SM,Pearson J

    更新日期:1997-02-01 00:00:00

  • Coping with parental quarrels.

    abstract::Children's reactions to parental quarrels were investigated in a general population sample of children between 9 and 12 years old. One hundred and thirty-nine families participated in the study. Approximately half the children were living in disharmonious families and half were in harmonious families. Mothers and chil...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-198903000-00006

    authors: Jenkins JM,Smith MA,Graham PJ

    更新日期:1989-03-01 00:00:00

  • Editorial: Promoting Quality Psychotherapy: It Is Not the Process but the Outcome That Matters!

    abstract::The article published in this issue of the Journal by Bear et al.1 is the first to use meta-analytic procedures to try to understand the value of psychotherapy for pediatric anxiety and depression as usually delivered in the community. The authors scoured the literature for psychotherapy clinical trials that used trea...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 社论

    doi:10.1016/j.jaac.2020.05.004

    authors: Walkup JT,Parkhurst J,Lavigne J

    更新日期:2020-07-01 00:00:00

  • Co-occurrence of conduct disorder and its adult outcomes with depressive and anxiety disorders: a review.

    abstract::Child and adult general population studies of psychiatric disorder were systematically reviewed for data on the co-occurrence of conduct disorder and its adult outcomes with depressive and anxiety disorders. For both sexes, both depressive and anxiety disorders co-occurred with conduct disorder (and its adult outcomes...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/00004583-199205000-00024

    authors: Zoccolillo M

    更新日期:1992-05-01 00:00:00

  • Prevalence of posttraumatic stress disorder and major depressive disorder in Tibetan refugee children.

    abstract:OBJECTIVE:In an exploratory survey the prevalence of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) was estimated in children who escaped from Tibet and found refuge in Tibetan settlements in India. METHOD:As part of an exploratory mission of the international medical relief organization Doct...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199808000-00018

    authors: Servan-Schreiber D,Le Lin B,Birmaher B

    更新日期:1998-08-01 00:00:00

  • Influence of ethnic factors on behavior problems in indigenous Sami and majority Norwegian adolescents.

    abstract:OBJECTIVE:To explore the relationship between behavior problems and ethnic factors in indigenous minority Sami and Norwegian majority adolescents in northern Norway. METHOD:The Youth Self-Report (YSR) was completed by 249 Sami and 210 Norwegian students in junior high school, aged 13 to 16 years. Parents completed the...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199807000-00014

    authors: Kvernmo S,Heyerdahl S

    更新日期:1998-07-01 00:00:00

  • Case study: behavioral symptoms of pediatric HIV-1 encephalopathy successfully treated with clonidine.

    abstract::There are few reports of the behavioral manifestations in the pediatric population infected with human immunodeficiency virus type 1 (HIV-1). We report a case of a 4-year-old child with acquired immunodeficiency syndrome, whose initial manifestation of central nervous system involvement consisted of sudden onset of im...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-199503000-00014

    authors: Ceseña M,Lee DO,Cebollero AM,Steingard RJ

    更新日期:1995-03-01 00:00:00

  • The British Child and Adolescent Mental Health Survey 1999: the prevalence of DSM-IV disorders.

    abstract:OBJECTIVE:To describe the prevalence of DSM-IV disorders and comorbidity in a large population-based sample of British children and adolescents. METHOD:Using a one-phase design, 10,438 children were assessed using the Development and Well-Being Assessment (DAWBA), a structured interview with verbatim reports reviewed ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-200310000-00011

    authors: Ford T,Goodman R,Meltzer H

    更新日期:2003-10-01 00:00:00

  • Cognitive function in adolescence: testing for interactions between breast-feeding and FADS2 polymorphisms.

    abstract:OBJECTIVES:Breast-fed C-allele carriers of the rs174575 single nucleotide polymorphism in the fatty acyl desaturase 2 (FADS2) gene have been reported to show a 6.4 to 7 IQ point advantage over formula-fed C-allele carriers, with no effect of breast-feeding in GG carriers. An Australian sample was examined to determine ...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.jaac.2010.10.010

    authors: Martin NW,Benyamin B,Hansell NK,Montgomery GW,Martin NG,Wright MJ,Bates TC

    更新日期:2011-01-01 00:00:00

  • School-based interventions for anxious children.

    abstract:OBJECTIVE:To compare the effectiveness of three school-based interventions for anxious children: group cognitive-behavioral therapy (CBT) for children, group CBT for children plus parent training group, and no-treatment control. METHOD:Students (7-11 years old) in three elementary schools (N = 453) were screened using...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.chi.0000177323.40005.a1

    authors: Bernstein GA,Layne AE,Egan EA,Tennison DM

    更新日期:2005-11-01 00:00:00

  • Factor and latent class analysis of DSM-IVADHD symptoms in a school sample of Brazilian adolescents.

    abstract:OBJECTIVE:To evaluate the validity of the multidimensional construct proposed by DSM-IV for the diagnosis of attention-deficit/hyperactivity disorder (ADHD) in a school sample of young Brazilian adolescents. METHOD:An instrument including all 18 DSM-IVADHD symptoms was administered to 1,013 students aged 12 to 14 year...

    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

    pub_type: 杂志文章

    doi:10.1097/00004583-200106000-00017

    authors: Rohde LA,Barbosa G,Polanczyk G,Eizirik M,Rasmussen ER,Neuman RJ,Todd RD

    更新日期:2001-06-01 00:00:00