当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Mitochondria and ischemic reperfusion damage in the adult and in the developing brain.

Mitochondria and ischemic reperfusion damage in the adult and in the developing brain.

Abstract：

:The developing and the adult brain respond in similar ways to ischemia, but also display clear differences. For example, the relative contributions of necrosis and apoptosis to neuronal death may be different, such that apoptotic mechanisms would be more prevalent in the developing brain. During normal development, more than half of the neurons in some brain regions are removed through apoptosis, and effectors like caspase-3 are highly upregulated in the immature brain. Mitochondria are pivotal regulators of cell death through their role in energy production and calcium homeostasis, their capacity to release apoptogenic proteins and to produce reactive oxygen species. This review will summarize some of the current studies dealing with mitochondria-related mechanisms of ischemic brain damage, with special reference to developmental aspects.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Blomgren K,Zhu C,Hallin U,Hagberg H

doi

10.1016/s0006-291x(03)00628-4

subject

Has Abstract

pub_date

2003-05-09 00:00:00

pages

551-9

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006291X03006284

journal_volume

304

pub_type

杂志文章,评审

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • High concentrations of STOP protein induce a microtubule super-stable state.

    abstract：:We have previously shown that mammalian brain crude extracts contained two classes of stable microtubules: "cold stable" and "super-stable" microtubules. We now find that both species are generated by a single protein factor (STOP protein) in a dose dependent manner. These results show that STOP protein action can be ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91129-6

    authors： Job D,Rauch CT,Margolis RL

    更新日期：1987-10-14 00:00:00

  • Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes.

    abstract：:Chondrocyte mechanotransduction in response to mechanical loading is essential for the health and homeostasis of articular cartilage. The actin cytoskeleton has been implicated in cell mechanics and mechanotransduction. This study tests the hypothesis that loading modulates actin dynamics and organisation with subsequ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.06.185

    authors： Campbell JJ,Blain EJ,Chowdhury TT,Knight MM

    更新日期：2007-09-21 00:00:00

  • Analysis of the potency of various low molecular weight chemical chaperones to prevent protein aggregation.

    abstract：:Newly translated proteins must undergo proper folding to ensure their function. To enter a low energy state, misfolded proteins form aggregates, which are associated with many degenerative diseases, such as Huntington's disease and chronic kidney disease (CKD). Recent studies have shown the use of low molecular weight...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.03.019

    authors： Upagupta C,Carlisle RE,Dickhout JG

    更新日期：2017-04-22 00:00:00

  • Diversity within the JMJD2 histone demethylase family.

    abstract：:JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins in vivo. We found that JMJD2A and C dem...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.12.147

    authors： Shin S,Janknecht R

    更新日期：2007-02-23 00:00:00

  • Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei interacts with specific regions of the SV40 mini chromosome.

    abstract：:A recently described endo-exodeoxyribonuclease activity (1) was determined to interact preferentially with the origin/enhancer region and the 5' end of the late promoter region of the SV40 mini chromosome. The enzymatic activity has no preferential site of interaction with naked DNA, which suggests, the chromatin orga...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)90256-6

    authors： Quarless SA

    更新日期：1985-01-31 00:00:00

  • T2BP, a novel TRAF2 binding protein, can activate NF-kappaB and AP-1 without TNF stimulation.

    abstract：:TRAF2 is a key molecule involved in TNF signaling, which is crucial for the regulation of inflammatory processes. We have identified a novel TRAF2 binding protein, designated as T2BP (TRAF2 binding protein), by a mammalian two-hybrid screening approach. T2BP is a relatively small protein of 184 amino acids, which incl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.6315

    authors： Kanamori M,Suzuki H,Saito R,Muramatsu M,Hayashizaki Y

    更新日期：2002-01-25 00:00:00

  • NF-kappaB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter.

    abstract：:A 5T/6T polymorphism in the human MMP-3 promoter affects gene expression and impacts the risk and/or severity of various pathological conditions. Chromatin immunoprecipitation (ChIP) in human fibroblasts homozygous for the 6T site demonstrate that it is bound by NF-kappaB and ZBP-89 transcription factors in its native...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.03.002

    authors： Borghaei RC,Gorski G,Javadi M,Mariah Chambers.

    更新日期：2009-05-01 00:00:00

  • STI-571: an anticancer protein-tyrosine kinase inhibitor.

    abstract：:STI-571 (imatinib, Gleevec, Glivec, CGP 57148) is an inhibitor of the Abl group of protein-tyrosine kinases. One of these enzymes, the Bcr-Abl oncoprotein, results from the fusion of the BCR and ABL genes that result from the reciprocal chromosomal translocation that forms the Philadelphia chromosome. The Philadelphia...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/j.bbrc.2003.08.055

    authors： Roskoski R Jr

    更新日期：2003-10-03 00:00:00

  • Drastic Ca2+ sensitization of myofilament associated with a small structural change in troponin I in inherited restrictive cardiomyopathy.

    abstract：:Six missense mutations in human cardiac troponin I (cTnI) were recently found to cause restrictive cardiomyopathy (RCM). We have bacterially expressed and purified these human cTnI mutants and examined their functional and structural consequences. Inserting the human cTnI into skinned cardiac muscle fibers showed that...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.10.116

    authors： Yumoto F,Lu QW,Morimoto S,Tanaka H,Kono N,Nagata K,Ojima T,Takahashi-Yanaga F,Miwa Y,Sasaguri T,Nishita K,Tanokura M,Ohtsuki I

    更新日期：2005-12-23 00:00:00

  • Crystallization and some properties of acetylpolyamine amidohydrolase from Mycoplana bullata.

    abstract：:During the course of investigations on the catabolism of acetylpolyamines by microorganisms, we found that acetylpolyamine amidohydrolase was produced by Mycoplana bullata FERM BP-1845 and isolated the enzyme from the cell-free extract in crystalline form. The enzyme had an apparent molecular weight of 67 kDa and was ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80997-5

    authors： Fujishiro K,Ando M,Uwajima T

    更新日期：1988-12-30 00:00:00

  • Anti-HIV and anti-HBV activity and resistance profile of 2',3'-dideoxy-3'-thiacytidine (3TC) and its arylphosphoramidate derivative CF 1109.

    abstract：:A novel membrane-soluble prodrug of the 5'-monophosphate derivative of 3TC containing a phenyl group and the methyl ester of L-alanine linked to the phosphorus through a phosphoramidate bond with the primary amino moiety (designated Cf 1109) was prepared. The 3TC prodrug proved less potent an inhibitor of HIV-1 and HI...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.1181

    authors： Balzarini J,Wedgwood O,Kruining J,Pelemans H,Heijtink R,De Clercq E,McGuigan C

    更新日期：1996-08-14 00:00:00

  • Hydrophobic moieties in cations, anions, and alcohols promote the B-to-Z transition in poly[d(G-C)] and poly[d(G-m5C)].

    abstract：:Previous results from our laboratory showed that an increase in the nonpolar alkyl chain length in tetraalkylammonium cations is accompanied by greater efficiency in driving the B-to-Z transition. Analogous effects are observed when the hydrocarbon portion of carboxylate anions and alcohols is increased in size. The m...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)91737-3

    authors： McDonnell NB,Preisler RS

    更新日期：1989-10-16 00:00:00

  • Increase in junctional conductance caused by isoproterenol in heart cell pairs is suppressed by cAMP-dependent protein-kinase inhibitor.

    abstract：:The influence of isoproterenol (10(-6) M) on junctional conductance of cell pairs isolated from adult rat ventricle was investigated using two separated voltage-clamp circuits. The drug increased the junctional conductance by 40% (S.E. +/- 11%) (n = 10) within 20 sec. In experiments in which an inhibitor of cAMP depen...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(88)90169-6

    authors： De Mello WC

    更新日期：1988-07-29 00:00:00

  • Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of substrate interactions.

    abstract：:The adsorption of D-fructose within the lumen of the human small intestine is thought to be mediated by the GLUT5 isoform of the human facilitative sugar transporter family. This isoform has been expressed in oocytes and shown to be capable of D-fructose transport. Some debate remains regarding the absolute substrate ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7204

    authors： Kane S,Seatter MJ,Gould GW

    更新日期：1997-09-18 00:00:00

  • Effect of a novel thermogenic beta-adrenoceptor agonist (BRL 26830) on insulin resistance in soleus muscle from obese Zucker rats.

    abstract：:Young lean (Fa/?) and obese (fa/fa) rats were treated with the thermogenic beta-adrenoceptor agonist, BRL 26830, for 3 weeks. In lean rats this treatment had no effect on body weight but there was a marked increase in the insulin sensitivity of soleus muscle strips with respect to glycolytic rate. Treatment of obese r...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)90135-4

    authors： Challiss RA,Budohoski L,Newsholme EA,Sennitt MV,Cawthorne MA

    更新日期：1985-04-30 00:00:00

  • The activation of cAMP-dependent protein kinase is directly linked to the regulation of osteoblast proliferation (UMR-106) by parathyroid hormone.

    abstract：:In order to characterize the direct involvement of cAMP in the change of osteoblast proliferation by parathyroid hormone (PTH), we employed the diastereoisomers of adenosine 3',5'-cyclic phosphorothioate, Sp-cAMPS and Rp-cAMPS, which have been recently shown to act directly as agonist and antagonist, respectively in t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91992-l

    authors： Kano J,Sugimoto T,Fukase M,Fujita T

    更新日期：1991-05-31 00:00:00

  • A new fluorescence-based method to monitor the pH in the thylakoid lumen using GFP variants.

    abstract：:The ΔpH-dependent/Tat pathway is unique for using only the proton motive force for driving proteins transport across the thylakoid membrane in chloroplasts. 9-aminoacridine fluorescence quenching is widely used to monitor the ΔpH developed across the thylakoid membrane in the light. However, this method suffers from l...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.12.032

    authors： Yang H,Pu X,Wang L,Liu L,Theg SM

    更新日期：2017-04-22 00:00:00

  • Antiprogestin-receptor complexes: differences in the interaction of the antiprogestin RU38,486 and the progestin R5020 with the progesterone receptor of human breast cancer cells.

    abstract：:In order to understand the molecular basis for antiprogestin action, we have compared the interaction of the antiprogestin [3H]RU38, 486 (RU486) and the progestin [3H]R5020 with the progesterone receptor (PR). In both MCF-7 and T47D human breast cancer cells, we have observed marked differences in the sedimentation pr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)90946-0

    authors： Mullick A,Katzenellenbogen BS

    更新日期：1986-02-26 00:00:00

  • Co-culture of endothelial cells and patterned smooth muscle cells on titanium: construction with high density of endothelial cells and low density of smooth muscle cells.

    abstract：:Endothelialization has been considered a promising method to improve the biocompatibility of vascular implanted biomaterials. However, little is known about the anti-coagulation, anti-inflammatory, anti-atherosclerosis and anti-shedding property of the attached endothelial cells (ECs) and the relationship with their b...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.10.127

    authors： Li J,Zhang K,Wu J,Liao Y,Yang P,Huang N

    更新日期：2015-01-09 00:00:00

  • DNT cell inhibits the growth of pancreatic carcinoma via abnormal expressions of NKG2D and MICA in vivo.

    abstract：:This research aimed to investigate the effects of natural killer group 2 member D (NKG2D) and its ligands major histocompatibility complex class I chain-related molecules A(MICA) in DNT cell killing pancreatic carcinoma. Antibodies adsorption was used to separate DNT cell from human peripheral blood. Human pancreatic ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.11.085

    authors： Xu H,Zhu XX,Chen J

    更新日期：2016-01-08 00:00:00

  • alpha-Crystallin facilitates the reactivation of hydrogen peroxide-inactivated rhodanese.

    abstract：:It was previously shown that rhodanese, inactivated with hydrogen peroxide, could only be reactivated in the presence of a reductant or the substrate thiosulfate if these reagents were added soon after inactivation and if the oxidant was removed. Here, we report on the facilitated reactivation (75%) of hydrogen peroxi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3165

    authors： Del Fierro D,Zardeneta G,Mendoza JA

    更新日期：2000-08-02 00:00:00

  • Transient inositol (1,4,5) trisphosphate accumulation under vasopressin stimulation in WRK1 cells: correlation with intracellular calcium mobilization.

    abstract：:In the rat mammary tumoral cell line (WRK1 cells), vasopressin was previously described to stimulate a phospholipase C. In this study, we have analysed the effect of vasopressin both on intracellular calcium mobilization and on the accumulation of inositol phosphates. Maximal concentration of vasopressin simultaneousl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)92201-8

    authors： Mouillac B,Balestre MN,Guillon G

    更新日期：1989-03-31 00:00:00

  • Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta.

    abstract：:The somatostatin analogue, TT-232 inhibits cell proliferation and induces apoptosis in a variety of tumor cells both in vivo and in vitro. While the early transient activation of Erk/MAPK was found to be important for the induction of cell cycle arrest, the signaling pathway leading to the activation of Erk/MAPK had n...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5811

    authors： Steták A,Csermely P,Ullrich A,Kéri G

    更新日期：2001-11-02 00:00:00

  • The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells.

    abstract：:Erythroid progenitor cells synthesize 12-hydroxyeicosatetraenoic acid (12-HETE) and 15-hydroxyeicosatetraenoic acid (15-HETE) when stimulated by erythropoietin (Ep). Maximal stimulation of 12-HETE production occurred at one hour, whereas 15-HETE activity remained constant in response to Ep for 24 hours. Lipoxygenase-s...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(87)80134-1

    authors： Beckman BS,Mason-Garcia M,Nystuen L,King L,Fisher JW

    更新日期：1987-08-31 00:00:00

  • Estimation of the lipophilicity of anti-HIV nucleoside analogues by determination of the partition coefficient and retention time on a Lichrospher 60 RP-8 HPLC column.

    abstract：:There is a close linear correlation between the log partition coefficient (Pa) of a series of 2'-deoxyriboside (dR), 2',3'-didehydro-3'-dideoxyriboside (ddeR), 2',3'-dideoxyriboside (ddR), 3'-fluoro-2',3'-dideoxyriboside (FddR) and 3'-azido-2',3'-dideoxyriboside (AzddR) derivatives of uracil, cytosine, thymine, guanin...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(89)80063-4

    authors： Balzarini J,Cools M,De Clercq E

    更新日期：1989-01-31 00:00:00

  • A hydrocortisone derivative binds to GAPDH and reduces the toxicity of extracellular polyglutamine-containing aggregates.

    abstract：:Huntington's disease (HD) has been recently shown to have a horizontally transmitted, prion-like pathology. Thus, the migration of polyglutamine-containing aggregates to acceptor cells is important for the progression of HD. These aggregates contain glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which increases the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.04.125

    authors： Lazarev VF,Mikhaylova ER,Dutysheva EA,Suezov RV,Guzhova IV,Margulis BA

    更新日期：2017-06-03 00:00:00

  • Effect of concentration on the cytotoxic mechanism of doxorubicin--apoptosis and oxidative DNA damage.

    abstract：:Anthracycline derivatives such as doxorubicin are part of many chemotherapeutic regimens and reach peak plasma concentrations of 5 microM. We investigated the cytotoxic mechanisms of various doxorubicin concentrations in MOLT-4 ALL-cells. Concentrations of up to 100 microM doxorubicin achieved similar cytotoxic effect...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.5898

    authors： Müller I,Jenner A,Bruchelt G,Niethammer D,Halliwell B

    更新日期：1997-01-13 00:00:00

  • Desensitization of human platelets by platelet activating factor.

    abstract：:Human platelets are less responsive to PAF at 37 degrees than at 25 degrees. They can be desensitized to the effects of PAF by pre-exposure to small concentrations. In both cases desensitization appears to be accompanied by a decreased affinity of the high affinity site for PAF rather than loss of binding sites. Alter...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(85)80120-0

    authors： Chesney CM,Pifer DD,Huch KM

    更新日期：1985-02-28 00:00:00

  • Calcium ion-regulated phospholipase C activity in bovine rod outer segments.

    abstract：:Bovine retinal rod outer segment membranes are enriched in a phosphoinositide-specific phosphodiesterase (phospholipase C) activity strictly modulated by free calcium ion concentration. The enzyme(s) was highly active on phosphatidylinositol 4,5-bisphosphate: maximal hydrolysis rate was attained at 10(-5)M Ca2+ and ac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)81054-x

    authors： Panfoli I,Morelli A,Pepe I

    更新日期：1990-11-30 00:00:00

  • Visualization of extracellular vesicles in the regenerating caudal fin blastema of zebrafish using in vivo electroporation.

    abstract：:Zebrafish have high regenerative ability in several organs including the fin. Although various mechanisms underlying fin regeneration have been revealed, some mechanisms remain to be elucidated. Recently, extracellular vesicles (EVs) have been the focus of research with regard to their role in cell-to-cell communicati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.10.024

    authors： Ohgo S,Sakamoto T,Nakajima W,Matsunaga S,Wada N

    更新日期：2020-12-17 00:00:00