Group B streptococcal conjugate vaccines.

abstract：BACKGROUND:A tailor-made serogroup B outer membrane vesicle vaccine was evaluated in the context of a serogroup B meningococcal epidemic dominated by Neisseria meningitidis strain B:4:P1.7b,4. OBJECTIVE:To determine the safety, reactogenicity and immunogenicity in infants aged 6-8 months of a meningococcal B vaccine d...

journal_title：Archives of disease in childhood

authors： Jackson C,Lennon DR,Sotutu VT,Yan J,Stewart JM,Reid S,Crengle S,Oster P,Ypma E,Aaberge I,Mulholland K,Martin DR

更新日期：2009-10-01 00:00:00

abstract：:Susceptibility to infections is a well known feature of Down's syndrome. The possible relation between this predisposition and the serum concentrations of the IgG subclasses was studied in 38 children with Down's syndrome aged 1-12 years. An age matched group of 50 healthy children served as controls. The serum concen...

journal_title：Archives of disease in childhood

authors： Annerén G,Magnusson CG,Lilja G,Nordvall SL

更新日期：1992-05-01 00:00:00

abstract：:The age distribution of anginose infectious mononucleosis in children was analysed retrospectively for the years 1966-85. During that period the disease became significantly more common in children of a young age and less common in older children. This shift could not be attributed either to socioeconomic conditions o...

journal_title：Archives of disease in childhood

authors： Spirer Z,Holtzman M,Melamed I,Shalit I

更新日期：1987-06-01 00:00:00

abstract：:In a newborn baby, suffering from persistent severe hypoglycaemia with convulsions glucagon deficiency was shown. Treatment with zinc-protamine-glucagon injection twice daily resulted in normal blood glucose levels. Motor development is delayed. ...

journal_title：Archives of disease in childhood

authors： Kollee LA,Monnens LA,Cecjka V,Wilms RM

更新日期：1978-05-01 00:00:00

abstract：:Ten patients with biotinidase deficiency were studied. Clinical findings at presentation varied with dermatological signs (dermatitis and alopecia), neurological abnormalities (fits, hypotonia, and ataxia), and recurrent infections being the most common features, although none of these occurred in every case. Biochemi...

journal_title：Archives of disease in childhood

authors： Wastell HJ,Bartlett K,Dale G,Shein A

更新日期：1988-10-01 00:00:00

abstract：:Sympathetic function was studied in 101 diabetic children and 102 age and sex matched control children, as part of a longitudinal study of the evolution of microvascular disease in the population of diabetic children and adolescents in Avon County. The median (range) age of the diabetic population was 13.5 (6.0-17.2) ...

journal_title：Archives of disease in childhood

authors： Karavanaki K,Davies AG,Hunt LP,Morgan MH,Baum JD

更新日期：1994-12-01 00:00:00

abstract：:Imaging has many uses, but in cases of suspected child abuse, radiographs and CT scans are vital in identifying fractures and head injury that may not be clinically obvious. There are growing concerns about the small but potential adverse effects of radiation, including cancer, in the paediatric population as a result...

journal_title：Archives of disease in childhood

authors： Bajaj M,Offiah AC

更新日期：2015-12-01 00:00:00

abstract：:No consistent differences were found in mean heights and weights of 170 schoolchildren aged 6--12 years with the sickle cell trait and 1247 schoolchildren with normal haemoglobin living in Dominica and Jamaica. ...

journal_title：Archives of disease in childhood

authors： Ashcroft MT,Desai P,Grell GA,Serjeant BE,Serjeant GR

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Data on the efficacy and safety of long-acting β2-agonists (LABA) in children are limited, and current guidelines recommend that LABA always be used with inhaled corticosteroids (ICS). OBJECTIVE:To compare asthma control, assessed by rescue medications use, in children prescribed LABA and ICS as a fixed-dos...

journal_title：Archives of disease in childhood

authors： Elkout H,McLay JS,Simpson CR,Helms PJ

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To study the effect of modified polyunsaturated fatty acid (PUFA) profiles of complementary food on long-chain (LC) PUFA composition in healthy infants. DESIGN:Double blinded, randomised, controlled intervention trial. SETTING:Dortmund, Germany. PATIENTS:Free-living sample of healthy term infants. METHODS...

journal_title：Archives of disease in childhood

authors： Schwartz J,Dube K,Sichert-Hellert W,Kannenberg F,Kunz C,Kalhoff H,Kersting M

更新日期：2009-11-01 00:00:00

abstract：:Six neonates with aneurysms of the vein of Galen are described: five were associated with an intracerebral arteriovenous fistula and presented with heart failure in the neonatal period; one had hydrocephalus at birth. Two infants died from intractable cardiac failure within 48 hours of age and two from progressive hyd...

journal_title：Archives of disease in childhood

authors： O'Donnabhain D,Duff DF

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:To investigate whether school readiness could be affected by placing electronic devices (EDs) in children's bedroom and whether the relationship was moderated by parental restriction and family socioeconomic status (SES). DESIGN:This is a cross-sectional study with bedroom ED placement and parental restricti...

journal_title：Archives of disease in childhood

authors： Fu KW,Ho FKW,Rao N,Jiang F,Li SL,Lee TM,Chan SH,Yung AW,Young ME,Ip P

更新日期：2017-12-01 00:00:00

abstract：:19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors w...

journal_title：Archives of disease in childhood

authors： Rizzoni G,Malekzadeh MH,Pennisi AJ,Ettenger RB,Uittenbogaart CH,Fine RN

更新日期：1980-07-01 00:00:00

abstract：:A retrospective study was made of 30 children with Leber's amaurosis (congenital retinal blindness). 24 presented with severe visual impairment, typical ophalmological findings, and absent electroretinograms. 6 other children, though presenting with marked visual loss and absent electroetinograms were later shown to b...

journal_title：Archives of disease in childhood

authors： Vaizey MJ,Sanders MD,Wybar KC,Wilson J

更新日期：1977-05-01 00:00:00

abstract：:Three cases are reported in which thrombi were found in the aorta at postmortem. In each case the thrombus had originated within the ductus arteriosus. We believe that in recent years the attention paid to the presence of indwelling cannulae as a cause of embolic phenomena in the newborn period has led to a reduction ...

journal_title：Archives of disease in childhood

authors： Knowlson GT,Marsden HB

更新日期：1978-02-01 00:00:00

abstract：AIM:To determine the impact of displacement values on doses in paediatric patients when using parenteral. To assess the option of using average displacement values (DV) in the preparation of parenteral medicines. METHOD:Over 500 Medusa1 monographs were analysed and 42 medicines were identified with a displacement valu...

journal_title：Archives of disease in childhood

authors： Lo A,Christiansen N,Bhatti H

更新日期：2016-09-01 00:00:00

abstract：:162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused pronounced side effects, and the mortality was 4.9%. The most common complications were infections: sep...

journal_title：Archives of disease in childhood

authors： Riikonen R,Donner M

更新日期：1980-09-01 00:00:00

abstract：:Lymphocytes bearing the T cell receptor gamma delta (TCR-gamma delta) were searched for in human early milk lymphocyte suspensions by two colour cytofluorimetric analysis. It was found that the proportion of TCR-gamma delta+ cells was twofold greater in colostrum than in either autologous or heterologous blood samples...

journal_title：Archives of disease in childhood

authors： Bertotto A,Castellucci G,Fabietti G,Scalise F,Vaccaro R

更新日期：1990-11-01 00:00:00

abstract：:Seven children with precocious puberty were treated with cyproterone acetate and their adrenal function studied. In each child the drug caused significant adrenal hypofunction which was secondary to adrenocorticotrophic hormone suppression. None of these children had clinical evidence of adrenal hypofunction and it is...

journal_title：Archives of disease in childhood

authors： Savage DC,Swift PG

更新日期：1981-03-01 00:00:00

abstract：:Two Japanese outbreaks of erythema infectiosum were investigated for evidence of human parvovirus infection by a solid phase antibody capture radioimmunoassay based on a monoclonal antibody to human parvovirus. Specific IgM and high concentrations of specific IgG were detected in 37 sera from 27 children with erythema...

journal_title：Archives of disease in childhood

authors： Okabe N,Koboyashi S,Tatsuzawa O,Mortimer PP

更新日期：1984-11-01 00:00:00

abstract：AIM:To produce a growth reference for British children with Williams syndrome. METHODS:The children and adults recruited into the study were all affiliated to the Williams Syndrome Foundation, a parent support group founded in 1979. They have all been shown to have a deletion of chromosome 7q11.23. One growth nurse (W...

journal_title：Archives of disease in childhood

authors： Martin ND,Smith WR,Cole TJ,Preece MA

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To simultaneously record tracheal and oesophageal pH in mechanically ventilated children to determine: (1) the feasibility and safety of the method; (2) the incidence of gastro-oesophageal reflux (GOR) and pulmonary contamination; and (3) their associated risk factors. DESIGN:Prospective study. SETTING:Paed...

journal_title：Archives of disease in childhood

authors： Hue V,Leclerc F,Gottrand F,Martinot A,Crunelle V,Riou Y,Deschildre A,Fourier C,Turck D

更新日期：1996-07-01 00:00:00

abstract：INTRODUCTION:Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in those children exposed to certain antiepileptic drugs (AEDs) in utero. The diagnosis of FACS is a clinical one and so excluding alternative diagnoses such as genetic disorders is essential. METHODS:We...

journal_title：Archives of disease in childhood

authors： Jackson A,Ward H,Bromley RL,Deshpande C,Vasudevan P,Scurr I,Dean J,Shannon N,Berg J,Holder S,Baralle D,Clayton-Smith J,DDD Study.

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Pelkonen AS,Malmberg LP,Mäkelä MJ,Saxen H,Tarkkanen J

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Silver-Russell syndrome (SRS) is an imprinted disorder characterised by intrauterine growth retardation, relative macrocephaly, failure to thrive, typical facial phenotype and frequent body asymmetry. Feeding difficulties are frequently noted, but no study described evolution of gastrointestinal signs during...

journal_title：Archives of disease in childhood

authors： Marsaud C,Rossignol S,Tounian P,Netchine I,Dubern B

更新日期：2015-04-01 00:00:00

abstract：:The ability to produce dihydroxylated metabolites of vitamin D was studied in a term neonate suffering from severe renal insufficiency. The infant died at age 26 days owing to end-stage renal failure and the necropsy examination showed a single dysplastic kidney weighing 1.5 g. At age 2 weeks the serum levels of the d...

journal_title：Archives of disease in childhood

authors： Alkalay A,Mogilner BM,Nissim F,Edelstein S

更新日期：1983-01-01 00:00:00

abstract：:Metabolites of vitamin D were measured in plasma from 83 patients with idiopathic infantile hypercalcaemia syndrome who were mentally handicapped but had normal calcium values at the time of the study. No significant difference was detected in the mean plasma concentrations of 25-hydroxyvitamin D2, 1,25-dihydroxyvitam...

journal_title：Archives of disease in childhood

authors： Martin ND,Snodgrass GJ,Cohen RD,Porteous CE,Coldwell RD,Trafford DJ,Makin HL

更新日期：1985-12-01 00:00:00

abstract：:The incidence of brain abnormalities determined by magnetic resonance in 30 consecutive children presenting with intractable complex partial seizures is reported. Images were optimised to visualise the hippocampus and cortical grey matter. Abnormalities of the hippocampus or temporal lobe were seen in all 19 children ...

journal_title：Archives of disease in childhood

authors： Cross JH,Jackson GD,Neville BG,Connelly A,Kirkham FJ,Boyd SG,Pitt MC,Gadian DG

更新日期：1993-07-01 00:00:00

abstract：AIMS:To examine the disease burden and epidemiology of community acquired rotavirus gastroenteritis in Austrian children treated in a paediatric practice. METHODS:A prospective, population based, multicentre study in four paediatric practices and two children's hospitals (Innsbruck and Leoben). Children

journal_title：Archives of disease in childhood

authors： Frühwirth M,Karmaus W,Moll-Schüler I,Brösl S,Mutz I

更新日期：2001-05-01 00:00:00

abstract：:Cerebral oedema is the most common cause of mortality and morbidity during the first day of conventional treatment for diabetic ketoacidosis in paediatric patients. It is possible that therapy contributes to its development. Risk factors that predispose to cerebral oedema should lead to an expansion of the intracellul...

journal_title：Archives of disease in childhood

authors： Carlotti AP,Bohn D,Halperin ML

更新日期：2003-02-01 00:00:00