Exome sequencing in patients with antiepileptic drug exposure and complex phenotypes.

abstract：:This study describes the pattern of oxygen consumption (VO2), rectal temperature (Tr), and acral skin temperature (Tac) in sleeping and resting (awake) burned children nursed in a thermoneutral environment. Measurements of respiratory gas exchange (VO2 and carbon dioxide production (VCO2)) were made using an open circ...

journal_title：Archives of disease in childhood

authors： Childs C,Little RA

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity. AIM:To determine the incidence and risk factors for skeletal morbidity in ALL children. PATIENTS AND METHODS:The medical records of all (n=186, boys=110) children presenting to a single centre ...

journal_title：Archives of disease in childhood

authors： Elmantaser M,Stewart G,Young D,Duncan R,Gibson B,Ahmed SF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To describe the significance of pericardial effusion (PE), mitral regurgitation (MR) and impaired systolic function in predicting coronary artery lesions (CAL) at diagnosis and follow-up in Kawasaki disease (KD). DESIGN:Echocardiographic records on admission, at 1-3 weeks of illness, and at 6-8 weeks of illn...

journal_title：Archives of disease in childhood

authors： Lega JC,Bozio A,Cimaz R,Veyrier M,Floret D,Ducreux C,Reix P,Di Filippo S

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of infant crying and maternal soothing techniques in relation to ethnic origin and other sociodemographic variables. DESIGN:A questionnaire survey among mothers of 2-3 month old infants registered at six child health clinics in Amsterdam, the Netherlands. SUBJECTS:A questionna...

journal_title：Archives of disease in childhood

authors： van der Wal MF,van den Boom DC,Pauw-Plomp H,de Jonge GA

更新日期：1998-10-01 00:00:00

abstract：:Three babies said to have had 'meconium stained liquor' were subsequently found never to have passed meconium. The green discoloured liquor was the result of bilious vomiting in utero secondary to intestinal obstruction. ...

journal_title：Archives of disease in childhood

authors： Griffiths DM,Burge DM

更新日期：1988-02-01 00:00:00

abstract：:Five cases are reported of spontaneous remission of chronic childhood thrombocytopenia four or more years after diagnosis. Other than typical features of chronic idiopathic thrombocytopenic purpura there were no obvious markers predictive of late remission, although a slow progressive recovery was common to four of th...

journal_title：Archives of disease in childhood

authors： Tait RC,Evans DI

更新日期：1993-05-01 00:00:00

abstract：:Two neonates with spontaneous rupture of the bladder and an otherwise normal genitourinary tract are described. Conservative management resulted in complete resolution of the lesion in one but the other child died from a coliform septicaemia. Necropsy showed a discrete ischaemic lesion in the fundus of the bladder. ...

journal_title：Archives of disease in childhood

authors： Morrell P,Coulthard MG,Hey EN

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Pelkonen AS,Malmberg LP,Mäkelä MJ,Saxen H,Tarkkanen J

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:To determine long-term seroprotection after serogroup C meningococcal (MenC) vaccination at the age of 9-12 years, with or without booster vaccination at the age of 13-15 years. DESIGN:Observational cohort study; follow-on from randomised study. SETTING:Participants were recruited from English secondary sc...

journal_title：Archives of disease in childhood

authors： de Whalley PC,Snape MD,Plested E,Thompson B,Nuthall E,Omar O,Borrow R,Pollard AJ

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To assess height and body mass index standard deviation scores up to 20 years after treatment for acute lymphoblastic leukaemia (ALL). SUBJECTS AND METHODS:Height and body mass index standard deviation scores were measured in 33 patients (14 boys and 19 girls) with childhood ALL at diagnosis, after the end o...

journal_title：Archives of disease in childhood

authors： Birkebaek NH,Clausen N

更新日期：1998-08-01 00:00:00

abstract：RATIONALE:Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. OBJECTIVE:To calculate potential cost savings attributable to increases in breastfeeding rates from the National Health Service perspective. DESIGN AND SETTINGS...

journal_title：Archives of disease in childhood

authors： Pokhrel S,Quigley MA,Fox-Rushby J,McCormick F,Williams A,Trueman P,Dodds R,Renfrew MJ

更新日期：2015-04-01 00:00:00

abstract：:Two neonates with severe culture proven pertussis were successfully treated with salbutamol 0.5 mg three times daily. There was a demonstrable decrease in the total number of coughing spasms, their mean duration and severity. In one baby this was shown by the transcutaneous oxygen tension measurements. ...

journal_title：Archives of disease in childhood

authors： Tam AY,Yeung CY

更新日期：1986-06-01 00:00:00

abstract：:The concentration of 27 amino acids in the vitreous humour was analysed in 120 cot deaths. Baseline data for age and postmortem interval are presented and the concentrations compared with the normal reference range for plasma. The results do not indicate that a specific aminoacidopathy is a factor in cot deaths. ...

journal_title：Archives of disease in childhood

authors： Patrick WJ,Logan RW

更新日期：1988-06-01 00:00:00

abstract：:Thirty nine infants with severe asphyxia (28 affected perinatally and 11 later) were studied by electrophysiological cerebral function monitoring (CFM) for periods varying from a half to 49 days. Nineteen infants died while still in intensive care and two died later from sequelae. Eighteen survived and were followed u...

journal_title：Archives of disease in childhood

authors： Bjerre I,Hellström-Westas L,Rosén I,Svenningsen N

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVES:To understand the experiences and perceptions of healthcare services of children with life-limiting and life-threatening conditions and their family members, including palliative care. DESIGN:Longitudinal qualitative interview study with children and their family members. Up to three in-depth interviews wer...

journal_title：Archives of disease in childhood

authors： Mitchell S,Slowther AM,Coad J,Dale J

更新日期：2020-11-16 00:00:00

abstract：:Rubella vaccination was offered to a cohort of schoolgirls 14 years and over whose immune state was unknown. This increased the percentage vaccinated or known to be immune from 86% to 90%. It is recommended that rubella vaccination should be offered to girls until they leave school at 16 years of age. ...

journal_title：Archives of disease in childhood

authors： Hodes DT

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To determine if exploratory factor analysis can identify subtypes comprising recognisable clinical patterns of the presenting signs and symptoms of children with joint hypermobility syndrome (JHS). PATIENTS:Eighty-nine children with JHS aged 6-16 years. METHODS:Twelve tests comprising anthropometric, muscul...

journal_title：Archives of disease in childhood

authors： Pacey V,Adams RD,Tofts L,Munns CF,Nicholson LL

更新日期：2015-01-01 00:00:00

abstract：:Syncope in childhood is very common. The vast majority of episodes are benign, and are due to neurocardiogenic syncope. Only a minority are due to something potentially more serious or life threatening. The diagnosis and differentiation of benign from more serious causes of syncope is made primarily by the history. In...

journal_title：Archives of disease in childhood

authors： McLeod KA

更新日期：2003-04-01 00:00:00

abstract：:We studied the effects on the family of childhood chronic renal failure by contrasting children with varying degrees of severity of illness with healthy controls. Disruption of family life was most common in families with the more severely ill children (on hospital haemodialysis) and there was a tendency for more ment...

journal_title：Archives of disease in childhood

authors： Reynolds JM,Garralda ME,Jameson RA,Postlethwaite RJ

更新日期：1988-07-01 00:00:00

abstract：:The prevalence of wheezing, 'asthma', treatment for 'asthma', and school absence as a result of wheezing in Nottingham was calculated from a questionnaire survey of parents of 4750 children in a random sample of primary schools. A response was achieved for 3805 (80%) children of whom 438 (11.5%) had had episodes of wh...

journal_title：Archives of disease in childhood

authors： Hill RA,Standen PJ,Tattersfield AE

更新日期：1989-02-01 00:00:00

abstract：:A previously described difference in newborn blood phenylalanine concentrations between those living in urban and non-urban areas in the south west of England has been confirmed and shown to be independent of the type of feed. Several factors including the place of abode, type of feed, birthweight, and the accuracy of...

journal_title：Archives of disease in childhood

authors： Morris AF,Holton JB,Burman D,Colley JR

更新日期：1983-04-01 00:00:00

abstract：:Cerebral oedema is the most common cause of mortality and morbidity during the first day of conventional treatment for diabetic ketoacidosis in paediatric patients. It is possible that therapy contributes to its development. Risk factors that predispose to cerebral oedema should lead to an expansion of the intracellul...

journal_title：Archives of disease in childhood

authors： Carlotti AP,Bohn D,Halperin ML

更新日期：2003-02-01 00:00:00

abstract：:Flow velocities in the basal cerebral arteries were studied by transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase...

journal_title：Archives of disease in childhood

authors： Bode H,Wais U

更新日期：1988-06-01 00:00:00

abstract：:When prescribing drugs for children, it is fundamental to acknowledge that they are distinct from adults with a different physiology and metabolism. They are also still maturing. The development of drugs with a primarily paediatric indication thus requires the trialling of these drugs in a paediatric population to ass...

journal_title：Archives of disease in childhood

authors： Prasad S

更新日期：2005-02-01 00:00:00

abstract：AIM:To assess the provision of UK paediatric and adolescent diabetes services and examine changes in service delivery since 2002. METHOD:Questionnaires were sent to the lead paediatric consultant from all paediatric and adolescent diabetes services (n=205). Questions were based on National Institute for Health and Cli...

journal_title：Archives of disease in childhood

authors： Gosden C,Edge JA,Holt RI,James J,Turner B,Winocour P,Walton C,Nagi D,Williams R,Matyka K

更新日期：2010-10-01 00:00:00

abstract：:Four children, including three infants, who died suddenly and unexpectedly are described. In three of the cases group A beta haemolytic streptococcus was cultured and in the fourth Streptococcus pneumoniae. The organism was grown from multiple sites including blood in two of them. Without microbiological investigation...

journal_title：Archives of disease in childhood

authors： Sharief N,Khan K,Conlan P

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. The National Institute for Health and Care Excellence (NICE) has issued...

journal_title：Archives of disease in childhood

authors： Marlow R,Mytton J,Maconochie IK,Taylor H,Lyttle MD

更新日期：2015-12-01 00:00:00

abstract：AIMS:To investigate the nature of the unifocal cortical abnormalities on FDG positron emission tomography (PET) in children with an epileptic encephalopathy but no focal abnormality on electroencephalogram or standard magnetic resonance imaging (MRI). METHODS:Repeat FDG PET, surface rendered high resolution MRI, and s...

journal_title：Archives of disease in childhood

authors： Parker AP,Ferrie CD,Keevil S,Newbold M,Cox T,Maisey M,Robinson RO

更新日期：1998-07-01 00:00:00

abstract：:Trigeminal neuralgia (TN) is a frequent cause of paroxysmal facial pain and headache in adults. Glossopharyngeal neuralgia (GPN) is less common, but can cause severe episodic pain in the ear and throat. Neurovascular compression of the appropriate cranial nerve as it leaves the brain stem is responsible for the sympto...

journal_title：Archives of disease in childhood

authors： Childs AM,Meaney JF,Ferrie CD,Holland PC

更新日期：2000-04-01 00:00:00

abstract：AIMS:To describe the epidemiology of intussusception and its relation to rotavirus associated hospitalisation in New Zealand. METHODS:National hospital discharge data between January 1998 and June 2003 for all children younger than 3 years of age with intussusception were reviewed. Independently, children from the sam...

journal_title：Archives of disease in childhood

authors： Chen YE,Beasley S,Grimwood K,New Zealand Rotavirus Study Group.

更新日期：2005-10-01 00:00:00