Glucose intolerance and resistin expression in rat offspring exposed to ethanol in utero: modulation by postnatal high-fat diet.

abstract：:The aim of this study was to identify and characterize binding sites for inhibin in primary cultures of ovine anterior pituitary cells. Recombinant human 31-kDa inhibin A was iodinated by an optimized lactoperoxidase procedure. Fractionation of the labeled protein by gel filtration chromatography on Sephadex G-100 in ...

journal_title：Endocrinology

authors： Hertan R,Farnworth PG,Fitzsimmons KL,Robertson DM

更新日期：1999-01-01 00:00:00

abstract：:Groups of female ferrets born in the laboratory received sc Silastic capsules containing testosterone (T), 5 alpha-dihydrotestosterone (DHT), 17 beta-estradiol (E), or no steroid for 15 days beginning on the day of birth; an additional group of male ferrets received empty sc capsules neonatally. All ferrets were gonad...

journal_title：Endocrinology

authors： Baum MJ,Gallagher CA,Martin JT,Damassa DA

更新日期：1982-09-01 00:00:00

abstract：:The neuroendocrine hormones ACTH and corticotropin- releasing factor (CRF), which are involved in the stress response, have acute effects on arterial pressure. New evidence indicates that urocortin (UCN), the putative agonist for the CRF type 2 receptor, has selective cardiovascular actions. The responses to long-term...

journal_title：Endocrinology

authors： Weisinger RS,Blair-West JR,Burns P,Denton DA,Purcell B,Vale W,Rivier J,Weisinger HS,May CN

更新日期：2004-12-01 00:00:00

abstract：:The ability of the adult pancreas to generate new insulin (beta) cells has been controversial because of difficulties in unequivocally identifying the precursor population. We recently determined that beta cells were generated during development from precursors that expressed the homeodomain-containing transcription f...

journal_title：Endocrinology

authors： Fernandes A,King LC,Guz Y,Stein R,Wright CV,Teitelman G

更新日期：1997-04-01 00:00:00

abstract：:Serum triiodothyronine (T3) in rats did not change if food intake was restricted without altering the composition of the diet. Feeding a hypocaloric low-protein high-carbohydrate diet caused increases in serum T3, while feeding a hypocaloric high-protein low-carbohydrate diet caused decreases in serum T3. These change...

journal_title：Endocrinology

authors： Glass AR,Mellitt R,Burman KD,Wartofsky L,Swerdloff RS

更新日期：1978-06-01 00:00:00

abstract：:Leptin, a circulating 16-kDa protein secreted by adipocytes, decreases body weight by reducing food intake and enhancing energy utilization. Leptin receptors that share homology to the glycoprotein gp130 have been recently cloned. In addition, differentially spliced leptin receptor messenger RNAs have been identified....

journal_title：Endocrinology

authors： Liu C,Liu XJ,Barry G,Ling N,Maki RA,De Souza EB

更新日期：1997-08-01 00:00:00

abstract：:Recently, heterogeneity of POMC mRNA content between intermediate lobe melanotropes of the rat pituitary gland was demonstrated by in situ hybridization of tissue sections. In the present study the heterogeneity of POMC mRNA content in dispersed rat pituitary cells has been investigated. Acutely dispersed cells from a...

journal_title：Endocrinology

authors： Hatfield JM,Daikh DI,Adelman JP,Douglass J,Bond CT,Allen RG

更新日期：1989-03-01 00:00:00

abstract：:Humanin is a peptide that is cytoprotective against stresses in many cell types. We investigated whether a potent humanin analogue S14G-humanin (HNG) would protect against chemotherapy-induced damage to normal cells without interfering with the chemotherapy-induced suppression of cancer cells. Young adult male mice we...

journal_title：Endocrinology

authors： Lue Y,Swerdloff R,Wan J,Xiao J,French S,Atienza V,Canela V,Bruhn KW,Stone B,Jia Y,Cohen P,Wang C

更新日期：2015-12-01 00:00:00

abstract：:Using a primary culture of neonatal rat heart, we investigated the properties of iodothyronine 5'-deiodinating activity in the heart. 125I- release from [125I] reverse T3 incubated with cell homogenates depended on the concentrations of protein and dithiothreitol, pH, incubation time, and temperature of the incubation...

journal_title：Endocrinology

authors： Mori Y,Nishikawa M,Toyoda N,Yonemoto T,Matsubara H,Inada M

更新日期：1991-06-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is one of the most important neurotransmitters that regulate the excitability of GnRH neurons. Numerous studies have shown that GABA activates Cl(-) currents in GnRH neurons, and these effects are antagonized by GABA(A) receptor antagonists. The GABA(B) receptor is a heterodimer composed...

journal_title：Endocrinology

authors： Zhang C,Bosch MA,Rønnekleiv OK,Kelly MJ

更新日期：2009-05-01 00:00:00

abstract：:A myometrial explant culture system was developed to investigate the effect of progesterone and the antiprogestagen RU486 on prostacyclin (PGI2) and thromboxane A2 (TXA2) synthesis by the rat myometrium. After culture, eicosanoid synthesis was stimulated with arachidonic acid (AA) and the calcium ionophore A23187 (A23...

journal_title：Endocrinology

authors： Jeremy JY,Dandona P

更新日期：1986-08-01 00:00:00

abstract：:The antigenic epitopes of human GH (hGH) have been investigated using monoclonal antibodies (Mabs) to hGH. A panel of 12 Mabs was incorporated into two-site binding assays in order to investigate the antigenic surface of hGH. Nine reaction patterns were observed. The Mabs were further characterized in terms of their c...

journal_title：Endocrinology

authors： Strasburger CJ,Kostyo J,Vogel T,Barnard GJ,Kohen F

更新日期：1989-03-01 00:00:00

abstract：:The uptake of [125I]T3 in rat skeletal muscle was investigated by incubating intact soleus muscles with a tracer amount of [125I]T3. At 37 C [125I]T3 uptake increased asymptotically; at 60 min the muscle contained 10% of the total [125I]T3 or 0.238 +/- 0.021% per mg wet tissue. At 0 C the [125I]T3 uptake was 1/5 of th...

journal_title：Endocrinology

authors： Pontecorvi A,Robbins J

更新日期：1986-12-01 00:00:00

abstract：:Infection-induced inflammation, frequently associated with increased production of proinflammatory cytokines, is considered a significant contributor to preterm birth. A G protein-coupled cannabinoid receptor 2 (CB2), encoded by Cnr2, is expressed in various immune cells and was shown to modulate immune responses. We ...

journal_title：Endocrinology

authors： Sun X,Cappelletti M,Li Y,Karp CL,Divanovic S,Dey SK

更新日期：2014-10-01 00:00:00

abstract：:The insulin-like growth factors (IGFs) stimulate the proliferation of human breast cancer cells, including the estrogen-dependent cell line MCF-7. These cells secrete regulatory IGF-binding proteins (IGFBPs) which may enhance or attenuate IGF-stimulated cell proliferation. In this study, we have used RIA to quantify t...

journal_title：Endocrinology

authors： Martin JL,Coverley JA,Pattison ST,Baxter RC

更新日期：1995-03-01 00:00:00

abstract：:Hypothalamic proopiomelanocortin (POMC)-derived MSH peptides and the melanocortin receptor antagonist, agouti-related protein (AgRP), interact to regulate energy balance. Both POMC and AgRP neurons express estrogen receptors, but little is known about estrogen regulation of the melanocortin system in the primate. We h...

journal_title：Endocrinology

authors： Xiao E,Kim AJ,Dutia R,Conwell I,Ferin M,Wardlaw SL

更新日期：2010-03-01 00:00:00

abstract：:Mouse fibroblast cell lines which secrete bovine (b) GH have been generated. This was accomplished by cotransforming mouse L cells (thymidine kinase-negative [TK-] and adenine phosphoribosyl transferase-negative [APRT-]) with DNA molecules encoding the Rous sarcoma virus-long-terminal repeat and bGH genes along with t...

journal_title：Endocrinology

authors： Leung FC,Jones B,Steelman SL,Rosenblum CI,Kopchick JJ

更新日期：1986-10-01 00:00:00

abstract：:Previous descriptions of pulsatile LH release in immature female rats have been mostly inaccurate because of infrequent blood sampling, discontinuous and unbalanced blood replacement procedures, and possibly because of the use of a heterologous RIA. The present study was undertaken to circumvent these problems and to ...

journal_title：Endocrinology

authors： Urbanski HF,Ojeda SR

更新日期：1985-08-01 00:00:00

abstract：:Primary ovarian insufficiency (POI) resulting from ovarian autoimmunity is a poorly understood clinical condition lacking in effective treatments. Understanding the targets of the autoimmune response and induction of ovarian-specific tolerance would allow development of focused therapies to preserve fertility in an at...

journal_title：Endocrinology

authors： Otsuka N,Tong ZB,Vanevski K,Tu W,Cheng MH,Nelson LM

更新日期：2011-06-01 00:00:00

abstract：:Adult rats which have received monosodium-L-glutamate (MSG, 4 mg/g BW) on alternate days for the first 10 days of life manifest central nervous system lesions largely restricted to the retina and the arcuate nucleus of the hypothalamus in which nearly 90% of the perikarya are destroyed, leaving axons in passage intact...

journal_title：Endocrinology

authors： Greeley GH Jr,Nicholson GF,Nemeroff CB,Youngblood WW,Kizer JS

更新日期：1978-07-01 00:00:00

abstract：:Artificial copulomimetic cervical stimulation (CS) induces an immediate release of oxytocin (OT) and prolactin (PRL) followed by a daily PRL rhythm characterized by nocturnal and diurnal surges. Although we have shown that the initial release of PRL is induced by the immediate release of OT, we tested whether the PRL ...

journal_title：Endocrinology

authors： Helena CV,McKee DT,Bertram R,Walker AM,Freeman ME

更新日期：2009-07-01 00:00:00

abstract：:In rats, protein hydrolysates (peptones) stimulate cholecystokinin (CCK) release both in vivo and in a model of isolated vascularly perfused duodeno-jejunum. However, the mechanisms involved in peptone-induced stimulation of CCK cells are not well understood. In particular, the possibility that peptones may directly i...

journal_title：Endocrinology

authors： Cordier-Bussat M,Bernard C,Haouche S,Roche C,Abello J,Chayvialle JA,Cuber JC

更新日期：1997-03-01 00:00:00

abstract：:Thyroid hormones play a major role in body homeostasis, regulating energy expenditure and cardiovascular function. Given that obese people or athletes might consider rapid weight loss as beneficial, voluntary intoxication with T4 preparations is a growing cause for thyrotoxicosis. However, the long-lasting effects of ...

journal_title：Endocrinology

authors： Hoefig CS,Harder L,Oelkrug R,Meusel M,Vennström B,Brabant G,Mittag J

更新日期：2016-07-01 00:00:00

abstract：:Recent studies from our laboratory indicate that high density lipoproteins (HDL) and apolipoproteins-AI, -AII, and -CI stimulate the release of human placental lactogen (hPL) from human placental explants and trophoblast cells. However, the intracellular mechanisms by which HDL stimulate hPL release are unknown. Since...

journal_title：Endocrinology

authors： Wu YQ,Jorgensen EV,Handwerger S

更新日期：1988-10-01 00:00:00

abstract：:FSH has been shown to stimulate the uptake of calcium in cultured rat Sertoli cells, resulting in an increase in cytosolic calcium concentrations. One possibility which has been put forth is that the FSH receptor per se may act as a calcium channel. This is all the more tantalizing given the proposed structure of this...

journal_title：Endocrinology

authors： Shibata EF,Matsuda JJ,Volk KA,Collison KA,Segaloff DL

更新日期：1992-08-01 00:00:00

abstract：:We previously examined the segregation patterns of two polymorphic restriction enzyme sites for EcoRI and HindIII in the 3'-flanking region of human CG-alpha gene in placenta and choriocarcinoma. We observed that a unique combination of restriction sites predominates in choriocarcinoma while this pattern was rare in p...

journal_title：Endocrinology

authors： Otani T,Boime I

更新日期：1986-11-01 00:00:00

abstract：:Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in the arcuate nucleus play a key role in GnRH pulse generation, with kisspeptin driving GnRH release and neurokinin B (NKB) and dynorphin acting as start and stop signals, respectively. In this study, we tested this hypothesis...

journal_title：Endocrinology

authors： Goodman RL,Hileman SM,Nestor CC,Porter KL,Connors JM,Hardy SL,Millar RP,Cernea M,Coolen LM,Lehman MN

更新日期：2013-11-01 00:00:00

abstract：:Mesenchymal stem cells can differentiate into mature chondrocytes, osteoblasts, and adipocytes. Excessive and dysfunctional visceral adipocytes increase upon menopause and importantly contribute to altered metabolism in postmenopausal women. We previously showed both plasma membrane and nuclear estrogen receptors alph...

journal_title：Endocrinology

authors： Ahluwalia A,Hoa N,Ge L,Blumberg B,Levin ER

更新日期：2020-11-01 00:00:00

abstract：:The effect of constant infusions of bovine TSH in different concentrations on the pattern of T4 and T3 secretion was examined in perfused canine thyroids isolated in situ. Each of the thyroid lobes was isolated and perfused in each animal. It was thus possible to examine the effect of two different concentrations of T...

journal_title：Endocrinology

authors： Laurberg P

更新日期：1977-03-01 00:00:00

abstract：:We have studied regulation of the glucose transporter by thyroid hormone in ARL 15 cells, a thyroid hormone-responsive cell line derived from rat liver, T3 treatment (5 x 10(-8) M for 48 h) of confluent cell monolayers grown in thyroid hormone-deficient medium increased the rate of uptake of [3H] 2-deoxyglucose by 2.3...

journal_title：Endocrinology

authors： Weinstein SP,Watts J,Graves PN,Haber RS

更新日期：1990-03-01 00:00:00