The rhythmic secretion of mating-induced prolactin secretion is controlled by prolactin acting centrally.

abstract：:A transient increase in serum progesterone concentrations (to 1 ng/ml for 1-2 days) is observed in the majority of ewes before the first estrous cycle of the breeding season. To determine whether such a brief antecedent rise in progesterone ensures initiation of a full-length cycle by the next LH surge, synthetic GnRH...

journal_title：Endocrinology

authors： Legan SJ,I'Anson H,Fitzgerald BP,Akaydin MS Jr

更新日期：1985-10-01 00:00:00

abstract：:Hypothalamic enzymatic activities capable of degrading LHRH may play a physiological role in the neuroendocrine control of LHRH. There is increasing evidence, however, that these enzymes are not peptide specific. The present study in the ewe analyzed the possibility that the specificity of LHRH-degrading activity (LHR...

journal_title：Endocrinology

authors： Advis JP,Kuljis RO,Dey G

更新日期：1985-06-01 00:00:00

abstract：:Two experiments tested whether serotonergic neurons participate in the acute feedback effects of estradiol on LH and PRL secretion. In the first study, ovariectomized female rats received oil vehicle or estradiol benzoate and were killed 3 h later. The turnover of serotonin [5-hydroxytryptamine (5-HT)] in microdissect...

journal_title：Endocrinology

authors： Johnson MD,Crowley WR

更新日期：1983-12-01 00:00:00

abstract：:PRL gene expression in the anterior pituitary has been the focus of intensive investigation for many years, but very little information is available on the actual dynamics by which this process occurs in individual mammotrope cells. Here, we used single cell bioluminescent imaging microscopy and a recently refined rep...

journal_title：Endocrinology

authors： Shorte SL,Leclerc GM,Vazquez-Martinez R,Leaumont DC,Faught WJ,Frawley LS,Boockfor FR

更新日期：2002-03-01 00:00:00

abstract：:Puberty is associated with an increase in the plasma concentration of sex steroids, GH, and insulin-like growth factor-I (IGF-I). Gonadal steroid hormones are important for the normal pubertal growth spurt and skeletal growth. The mechanism by which gonadal steroids induce skeletal growth is still not fully understood...

journal_title：Endocrinology

authors： Maor G,Segev Y,Phillip M

更新日期：1999-04-01 00:00:00

abstract：:Selective inhibitors of sodium glucose cotransporter-2 (SGLT2) are widely used for the treatment of type 2 diabetes and act primarily to lower blood glucose by preventing glucose reabsorption in the kidney. However, it is controversial whether these agents also act on the pancreatic islet, specifically the α cell, to ...

journal_title：Endocrinology

authors： Dai C,Walker JT,Shostak A,Bouchi Y,Poffenberger G,Hart NJ,Jacobson DA,Calcutt MW,Bottino R,Greiner DL,Shultz LD,McGuinness OP,Dean ED,Powers AC

更新日期：2020-08-01 00:00:00

abstract：:A method has been developed for the purification of rat placental lactogen employing a specific radioreceptor assay (RRA). The method involves precipitation with ammonium sulfate, gel filtration on Sephadex G-100, ion-exchange chromatography on DEAE-cellulose and CM-Sephadex, and preparative isoelectric focusing. The ...

journal_title：Endocrinology

authors： Roberston MC,Friesen HG

更新日期：1975-09-01 00:00:00

abstract：:The effects of peripheral glucagon like peptide-1 receptor (GLP-1R) stimulation on feeding, gastric emptying, and energetic responses involve vagal transmission and central nervous system processing. Despite a lack of studies aimed at determining which central nervous system regions are critical for the GLP-1R respons...

journal_title：Endocrinology

authors： Hayes MR,Skibicka KP,Grill HJ

更新日期：2008-08-01 00:00:00

abstract：:The effects of estradiol valerate and constant light exposure on the histological appearance of the arcuate nucleus were assessed in female rats. Both of these treatments caused significant increases in the numbers of reactive microglial cells and astrocytic granules in the nucleus. Ovariectomy before either treatment...

journal_title：Endocrinology

authors： Brawer JR,Schipper H,Naftolin F

更新日期：1980-07-01 00:00:00

abstract：:Insulin receptors were measured in cultured Zajdela rat hepatoma cells (ZHC cells), a stable cell line which presents differentiated hepatic functions. The number of sites was 50,000/cell at 2 C, and the dissociation constant for high affinity binding was 1.6 x 10(-10) M. Down-regulation of receptors occurred rapidly ...

journal_title：Endocrinology

authors： Capeau J,Flaig-Staedel C,Beck JP,Picard J

更新日期：1982-09-01 00:00:00

abstract：:To determine the presence of a PRL-binding protein (PRL-BP) in rat serum, female rats were ovariectomized and administered sc estradiol benzoate capsules. Serum was incubated with [125I]rat PRL (rPRL) for 1 h at 37 C with or without different doses of rPRL, ovine PRL (oPRL), or rGH. Separation of the [125I]rPRL-PRL-BP...

journal_title：Endocrinology

authors： Cohen H,Guillaumot P,Sabbagh I

更新日期：1993-06-01 00:00:00

abstract：:Intravascular injections of adrenocorticotropic hormone in hypophysectomized rats were approximately 3 times more effective in stimulating increases in plasma corticosteroid concentration when given at the offset rather than the onset of the daily photoperiod (12 h:12 h light-dark cycle). Reversal of the photoperiodic...

journal_title：Endocrinology

authors： Ottenweller JE,Meier AH,Ferrell BR,Horseman ND,Proctor A

更新日期：1978-11-01 00:00:00

abstract：:To assess a possible regulatory influence of opioids upon anterior pituitary function in the chimpanzee, we evaluated the effects of the specific opiate receptor antagonist naloxone and the agonistic enkephalin analog [D-Ala2, MePhe4,Met(o)-ol]enkephalin (FK 33-824; Sandoz) on serum levels of PRL, cortisol, FSH, and L...

journal_title：Endocrinology

authors： Gosselin RE,Blankstein J,Dent DW,Hobson WC,Fuller GB,Reyes FI,Winter JS,Faiman C

更新日期：1983-06-01 00:00:00

abstract：:Vitellogenin (Vg) is a major yolk protein precursor in numerous oviparous animals. Numerous studies in bilateral oviparous animals have shown that Vg sequences are conserved across taxa and that Vgs are synthesized by somatic-cell lineages, transported to and accumulated in oocytes, and eventually used for supporting ...

journal_title：Endocrinology

authors： Shikina S,Chen CJ,Chung YJ,Shao ZF,Liou JY,Tseng HP,Lee YH,Chang CF

更新日期：2013-09-01 00:00:00

abstract：:Hypoxia, a common stressor in prematurity, leads to sexually dimorphic, short- and long-term effects on the adult hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes. We hypothesized that these effects are due to stress-induced increases in testosterone during early postnatal life. We ev...

journal_title：Endocrinology

authors： Gehrand AL,Phillips J,Malott K,Raff H

更新日期：2020-07-01 00:00:00

abstract：:Studies were undertaken to evaluate the effects of chronic morphine exposure on the negative and positive feedback effects of estradiol (E2) on LH and FSH secretion in ovariectomized rats. Two days of E2 exposure reduced at 1000 h and stimulated at 1600 h the serum LH concentration at each dose tested. Chronic exposur...

journal_title：Endocrinology

authors： Gabriel SM,Berglund LA,Simpkins JW

更新日期：1987-05-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP)-I has been reported to inhibit gastric acid secretion through stimulation of gastric somatostatin-14 (S-14) release. To establish whether some of the effects of CGRP-I on intestinal function might also be mediated through somatostatin, fetal rat intestinal cultures were treated w...

journal_title：Endocrinology

authors： Brubaker PL,Greenberg GR

更新日期：1993-12-01 00:00:00

abstract：:Organ weight was compared in adult mice with deletion of one (IRS-1-/+) or both (IRS-1-/-) copies of the insulin receptor substrate-1 (IRS-1) gene and IRS-1+/+ littermates. IRS-1-/+ mice showed modest reductions in weight of most organs in proportion to a decrease in body weight. IRS-1-/- mice showed major reductions ...

journal_title：Endocrinology

authors： Pete G,Fuller CR,Oldham JM,Smith DR,D'Ercole AJ,Kahn CR,Lund PK

更新日期：1999-12-01 00:00:00

abstract：:Term pregnancy human placenta contains hCG/LH receptor mRNA transcripts and immunoreactive receptor protein. Both the receptor transcripts and receptor proteins are present only in trophoblasts. These findings led us to investigate whether hCG can regulate its own synthesis in term pregnancy human placenta. Treatment ...

journal_title：Endocrinology

authors： Licht P,Cao H,Lei ZM,Rao CV,Merz WE

更新日期：1993-12-01 00:00:00

abstract：:The endocrine-disrupting chemical bisphenol A (BPA) increases adipose tissue mass in vivo and promotes adipogenesis in vitro; however, mechanisms explaining BPA's obesogenic effect remain unknown. We investigated the effects of gestational BPA and its analog, bisphenol S (BPS), exposure on the adipogenic differentiati...

journal_title：Endocrinology

authors： Pu Y,Gingrich JD,Steibel JP,Veiga-Lopez A

更新日期：2017-11-01 00:00:00

abstract：:Fundamental complications of insulin resistance and type 2 diabetes include the development of nonalcoholic fatty liver disease and an atherogenic fasting dyslipidemic profile, primarily due to increases in hepatic very-low-density lipoprotein (VLDL) production. Recently, central glucagon-like peptide-2 receptor (GLP2...

journal_title：Endocrinology

authors： Taher J,Baker C,Alvares D,Ijaz L,Hussain M,Adeli K

更新日期：2018-09-01 00:00:00

abstract：:Smoltification is a transformation that occurs in some species of salmon, during which solitary fish in fresh water become schooling fish and migrate to the sea. This process is accompanied by large increases in plasma T4. T4 secretion rate and other parameters of T4 metabolism in juvenile coho salmon were estimated b...

journal_title：Endocrinology

authors： Specker JL,DiStefano JJ 3rd,Grau EG,Nishioka RS,Bern HA

更新日期：1984-07-01 00:00:00

abstract：:Circulating levels of calcitonin precursors (CTpr), including procalcitonin (ProCT), increase up to several thousand-fold in human sepsis, and immunoneutralization improves survival in two animal models of this disease. Herein, we analyzed inflammation-mediated calcitonin I gene (CALC I) expression in human adipocyte ...

journal_title：Endocrinology

authors： Linscheid P,Seboek D,Nylen ES,Langer I,Schlatter M,Becker KL,Keller U,Müller B

更新日期：2003-12-01 00:00:00

abstract：:To determine if CRH and glucocorticoids are respectively required for hypophagia and catabolism in malnutrition, we have subjected wild-type (WT) and CRH knockout (KO) mice to dietary protein deprivation. Compared with WT mice, CRH KO mice exhibited greater decreases in food intake and negligible change in plasma cort...

journal_title：Endocrinology

authors： Jacobson L

更新日期：1999-08-01 00:00:00

abstract：:An increased activity of the hypothalamo-pituitary-adrenal axis resulting in exaggerated glucocorticoid secretion has been repeatedly described in patients with diabetes mellitus and in animal models of this disease. However, it has been pointed out that experimental diabetes is accompanied by a decreased glucocortico...

journal_title：Endocrinology

authors： Repetto EM,Sanchez R,Cipelli J,Astort F,Calejman CM,Piroli GG,Arias P,Cymeryng CB

更新日期：2010-01-01 00:00:00

abstract：:Prenatal stress is associated with altered behavior and hypothalamic-pituitary-adrenal (HPA) axis function postnatally. Recent studies suggest that these outcomes are dependent on the timing of the prenatal stress. The majority of these studies have been carried out in male offspring. We hypothesized that a short peri...

journal_title：Endocrinology

authors： Kapoor A,Matthews SG

更新日期：2008-12-01 00:00:00

abstract：:A time-course study was performed to correlate serum gonadotropin changes after ovariectomy (OVX) or OVX plus acute estradiol (E2) treatment with LHRH content and norepinephrine (NE) and dopamine (DA) content and turnover in the suprachiasmatic-medial preoptic region (SCH-PO), the medial basal hypothalamus (MBH), and ...

journal_title：Endocrinology

authors： Advis JP,McCann SM,Negro-Vilar A

更新日期：1980-10-01 00:00:00

abstract：:The amount of corticosterone bound to proteins in the adenohypophysis and dorsal hippocampus was studied concurrently with the plasma ACTH concentration in 4-week adrenalectomized male rats under steady-state conditions achieved by infusing the steroid at a constant rate for 45 min. Corticosterone binding was measured...

journal_title：Endocrinology

authors： Rotsztejn WH,Normand M,Lalonde J,Fortier C

更新日期：1975-07-01 00:00:00

abstract：:To determine the relative role of the androgenic and/or estrogenic components of the action of dehydroepiandrosterone (DHEA) on the histomorphology and structure of the rat mammary gland, ovariectomized (OVX) female animals received DHEA administered alone or in combination with the pure antiandrogen flutamide or the ...

journal_title：Endocrinology

authors： Sourla A,Martel C,Labrie C,Labrie F

更新日期：1998-02-01 00:00:00

abstract：:Dexamethasone, a synthetic glucocorticoid, inhibits the initial rate of transport of the nonmetabolizable amino acid, alpha-aminoisobutyric acid, in rat hepatoma tissue culture (HTC) cells. To determine whether this inhibition is mediated by the same proximal steps as is the steroidal induction of tyrosine aminotransf...

journal_title：Endocrinology

authors： Gelehrter TD,McDonald RA

更新日期：1981-08-01 00:00:00