Guidelines for the prevention of intravascular catheter-related infections.

Abstract:

BACKGROUND:Although many catheter-related bloodstream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. OBJECTIVE:To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. DATA SOURCES:The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. STUDIES INCLUDED:Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations. OUTCOME MEASURES:Reduction in CRBSI, catheter colonization, or catheter-related infection. SYNTHESIS:The recommended preventive strategies with the strongest supportive evidence are education and training of healthcare providers who insert and maintain catheters; maximal sterile barrier precautions during central venous catheter insertion; use of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central venous catheters for prevention of infection; and use of antiseptic/antibiotic-impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (ie, education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). CONCLUSION:Successful implementation of these evidence-based interventions can reduce the risk for serious catheter-related infection.

authors

O'Grady NP,Alexander M,Dellinger EP,Gerberding JL,Heard SO,Maki DG,Masur H,McCormick RD,Mermel LA,Pearson ML,Raad II,Randolph A,Weinstein RA,Healthcare Infection Control Practices Advisory Committee.

doi

10.1086/502007

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

759-69

issue

12

eissn

0899-823X

issn

1559-6834

pii

S0195941700080577

journal_volume

23

pub_type

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