Studies of ventilation efficiency in a protective isolation room by the use of a scale model.

Abstract:

OBJECTIVE:To assess the ability of a protective isolation room ventilation system to reduce patient exposure to airborne infectious agents, using a small-scale model that permits cost-effective and unobtrusive study of relevant indices of performance. DESIGN:A one-half scale model of a protective isolation room at the University of Minnesota Hospital was constructed and equipped for tracer gas experiments to assess ventilation efficiency. MEASUREMENTS:Tracer gas (SF6) was injected into the model supply air. Tracer gas concentration was recorded over time and analyzed to determine local and room mean age of air. Age of air is a direct measurement of ventilation efficiency and can be used to predict patient exposure to contamination. RESULTS:Although for the room taken as a whole, ventilation efficiency was close to 50% (a value corresponding to perfect mixing), the experimental results for the local mean age of air indicate that some parts of the model were ventilated much better than others. CONCLUSION:Room air exchange rate is only one parameter useful in assessing ventilation in patient areas. Effective distribution of ventilation air also is critical to the control of airborne contamination. Areas of the room with poor ventilation would be expected to have higher concentrations of airborne infectious agents and other contaminants. Patient exposure can be minimized by placing the patient in well-ventilated areas of the room. Improved ventilation designs may reduce patient exposure further without increasing actual airflow rate.

authors

Marshall JW,Vincent JH,Kuehn TH,Brosseau LM

doi

10.1086/647181

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

5-10

issue

1

eissn

0899-823X

issn

1559-6834

journal_volume

17

pub_type

杂志文章
  • Clinical Characteristics and Outcomes of Hematologic Malignancy Patients With Positive Clostridium difficile Toxin Immunoassay Versus Polymerase Chain Reaction Test Results.

    abstract::In a cohort of inpatients with hematologic malignancy and positive enzyme immunoassay (EIA) or polymerase chain reaction (PCR) Clostridium difficile tests, we found that clinical characteristics and outcomes were similar between these groups. The method of testing is unlikely to predict infection in this population, a...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2018.83

    authors: Ziegler M,Landsburg D,Pegues D,Alby K,Gilmar C,Bink K,Gorman T,Moore A,Bonhomme B,Omorogbe J,Tango D,Tolomeo P,Han JH

    更新日期:2018-07-01 00:00:00

  • Investigation of an outbreak of central venous catheter-associated bloodstream infection due to contaminated water.

    abstract::An outbreak of central venous catheter-associated bloodstream infections was reported in a hospital in Ecuador. Commercially produced ampoules of water for injection were found to be contaminated with Burkholderia cepacia and Myroides odoratus. Removal of these ampoules yielded a 10-fold reduction in the incidence of ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/533543

    authors: Douce RW,Zurita J,Sanchez O,Cardenas Aldaz P

    更新日期:2008-04-01 00:00:00

  • Public reporting of health care-associated infections (HAIs): approach to choosing HAI measures.

    abstract:OBJECTIVE:To develop a method for selecting health care-associated infection (HAI) measures for public reporting. CONTEXT:HAIs are common, serious, and costly adverse outcomes of medical care that affect 2 million people in the United States annually. Thirty-seven states have introduced or passed legislation requiring...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/660873

    authors: Passaretti CL,Barclay P,Pronovost P,Perl TM,Maryland Health Care Commission Health Care–Associated Infection Technical Advisory Committee.

    更新日期:2011-08-01 00:00:00

  • Personal protective equipment management and policies: European Network for Highly Infectious Diseases data from 48 isolation facilities in 16 European countries.

    abstract:OBJECTIVE:To collect data about personal protective equipment (PPE) management and to provide indications for improving PPE policies in Europe. DESIGN:Descriptive, cross-sectional survey. SETTING AND PARTICIPANTS:Data were collected in 48 isolation facilities in 16 European countries nominated by National Health Auth...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/667729

    authors: De Iaco G,Puro V,Fusco FM,Schilling S,Maltezou HC,Brouqui P,Gottschalk R,Bannister B,Brodt HR,Siikamaki H,Perronne C,Brantsæter AB,Fjellet AL,Ippolito G,European Network for Highly Infectious Diseases Working Group.

    更新日期:2012-10-01 00:00:00

  • Eradication of amebiasis in a large institution for adults with mental retardation in Taiwan.

    abstract:OBJECTIVE:Investigation of a program to eradicate amebiasis using consecutive intensive mass screenings followed by medication in a large institute for adults with mental retardation in Taiwan. DESIGN:Prospective cohort study, with 3 years of follow-up. SETTING:A large, 450-bed institution for adults with mental reta...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/518351

    authors: Su SB,Guo HR,Chuang YC,Chen KT,Lin CY

    更新日期:2007-06-01 00:00:00

  • Postoperative burden of hospital-acquired Clostridium difficile infection.

    abstract::OBJECTIVE Clostridium difficile infection (CDI) is a common hospital-acquired infection. Previous reports on the incidence, risk factors, and impact of CDI on resources in the surgical population are limited. In this context, we study CDI across diverse surgical settings. METHODS We prospectively identified patients w...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2014.8

    authors: Abdelsattar ZM,Krapohl G,Alrahmani L,Banerjee M,Krell RW,Wong SL,Campbell DA,Aronoff DM,Hendren S

    更新日期:2015-01-01 00:00:00

  • One-week versus 2-day ventilator circuit change in neonates with prolonged ventilation: cost-effectiveness and impact on ventilator-associated pneumonia.

    abstract:OBJECTIVE:To investigate the impact of 1-week ventilator circuit change on ventilator-associated pneumonia and its cost-effectiveness compared with a 2-day change. DESIGN:An observational cohort study. SETTING:A tertiary level neonatal intensive care unit in a university-affiliated teaching hospital in Taiwan. Patien...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2014.48

    authors: Chu SM,Yang MC,Hsiao HF,Hsu JF,Lien R,Chiang MC,Fu RH,Huang HR,Hsu KH,Tsai MH

    更新日期:2015-03-01 00:00:00

  • Exclusion of noninfectious medical waste from the contaminated waste stream.

    abstract::The purpose of this study was to determine whether any waste was labeled incorrectly as infectious or contained material that could be recycled. Waste generated in preparation for surgery was separated and weighed. Of 530 lbs of operating room waste, 40 lbs were noninfectious, largely plastic and paper. The results of...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647693

    authors: Francis MC,Metoyer LA,Kaye AD

    更新日期:1997-09-01 00:00:00

  • Reducing indwelling urinary catheter use through staged introduction of electronic clinical decision support in a multicenter hospital system.

    abstract:OBJECTIVE:To integrate electronic clinical decision support tools into clinical practice and to evaluate the impact on indwelling urinary catheter (IUC) use and catheter-associated urinary tract infections (CAUTIs).Design, Setting, and ParticipantsThis 4-phase observational study included all inpatients at a multicampu...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1017/ice.2018.114

    authors: Youngerman BE,Salmasian H,Carter EJ,Loftus ML,Perotte R,Ross BG,Furuya EY,Green RA,Vawdrey DK

    更新日期:2018-08-01 00:00:00

  • Unintended consequences of a reflex urine culture order set on appropriate antibiotic use.

    abstract::We evaluated the impact of reflex urine culture screen results on antibiotic initiation. More patients with positive urine screen but negative culture received antibiotics than those with a negative screen (30.5 vs 7.1%). Urine screen results may inappropriately influence antibiotic initiation in patients with a low l...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.230

    authors: Klein CN,Elman MR,Townes JM,Lewis JS,McGregor JC

    更新日期:2020-09-01 00:00:00

  • Challenges faced by hospital healthcare workers in using a syndrome-based surveillance system during the 2003 outbreak of severe acute respiratory syndrome in Taiwan.

    abstract::Because the severe acute respiratory syndrome (SARS) outbreak in Taiwan in 2003 was worsened by hospital infections, we analyzed 229 questionnaires (84.8% of 270 sent) completed by surveyed healthcare workers who cared for patients with SARS in 3 types of hospitals, to identify surveillance problems. Atypical clinical...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/508835

    authors: Shih FY,Yen MY,Wu JS,Chang FK,Lin LW,Ho MS,Hsiung CA,Su IJ,Marx MA,Sobel H,King CC

    更新日期:2007-03-01 00:00:00

  • Acquisition of Clostridium difficile on Hands of Healthcare Personnel Caring for Patients with Resolved C. difficile Infection.

    abstract::In an observational study, we found that healthcare personnel frequently acquired Clostridium difficile on their hands when caring for patients with recently resolved C. difficile infection (CDI) (<6 weeks after treatment) who were no longer under contact precautions. Continuing contact precautions after diarrhea reso...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.335

    authors: Shrestha SK,Sunkesula VC,Kundrapu S,Tomas ME,Nerandzic MM,Donskey CJ

    更新日期:2016-04-01 00:00:00

  • Effectiveness of hand-cleansing agents for removing methicillin-resistant Staphylococcus aureus from contaminated hands.

    abstract:OBJECTIVE:The effectiveness of hand-cleansing agents in removing a hospital strain of methicillin-resistant Staphylococcus aureus from artificially contaminated hands of five volunteers was studied. DESIGN:The products used were plain liquid soap, ethyl alcohol 70% (by weight), 10% povidone-iodine liquid soap (PVP-I),...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1086/501872

    authors: Guilhermetti M,Hernandes SE,Fukushigue Y,Garcia LB,Cardoso CL

    更新日期:2001-02-01 00:00:00

  • An integrated approach to methicillin-resistant Staphylococcus aureus control in a rural, regional-referral healthcare setting.

    abstract:OBJECTIVE:To curtail the prevalence and cross-transmission of methicillin-resistant Staphylococcus aureus (MRSA) in a rural healthcare setting. DESIGN:Before-after, quasi-experimental quality improvement study. SETTING:A regional-referral hospital, 5 affiliated nursing homes, and an outpatient MRSA clinic. INTERVENT...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/650445

    authors: Bowler WA,Bresnahan J,Bradfish A,Fernandez C

    更新日期:2010-03-01 00:00:00

  • Healthcare workers' knowledge and attitudes about pertussis and pertussis vaccination.

    abstract:OBJECTIVE:To determine knowledge and attitudes about pertussis and pertussis vaccination among healthcare workers (HCWs). DESIGN:Self-administered, Web-based survey. SETTING:Tertiary-care academic medical center. PARTICIPANTS:Medical center employees who participated in direct patient care were recruited to complete...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/521654

    authors: Goins WP,Schaffner W,Edwards KM,Talbot TR

    更新日期:2007-11-01 00:00:00

  • Impact of postdischarge surveillance on surgical site infection rates for several surgical procedures: results from the nosocomial surveillance network in The Netherlands.

    abstract:OBJECTIVE:To compare the number of surgical site infections (SSIs) registered after hospital discharge with respect to various surgical procedures and to identify the procedures for which postdischarge surveillance (PDS) is most important. DESIGN:Prospective SSI surveillance with voluntary PDS. Recommended methods for...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/506403

    authors: Manniën J,Wille JC,Snoeren RL,van den Hof S

    更新日期:2006-08-01 00:00:00

  • Annual tuberculin skin testing of employees at a university hospital: a cost-benefit analysis.

    abstract::The usefulness of routine annual tuberculin skin testing (purified protein derivative [PPD]) of hospital employees has been questioned. Between 1984 and the end of 1987 the PPD conversion rates of hospital employees at a university and psychiatric hospital in North Florida were compared. The number of employees in bot...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/645922

    authors: Raad I,Cusick J,Sherertz RJ,Sabbagh M,Howell N

    更新日期:1989-10-01 00:00:00

  • Ultraviolet powder versus ultraviolet gel for assessing environmental cleaning.

    abstract::We compared cleaning rates associated with use of a white ultraviolet (UV) powder versus a transparent UV gel among units with various degrees of previous experience with UV powder. The study outcome was the presence of discordant cleaning (removal of powder without the removal of gel, or vice versa). We found higher ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/663713

    authors: Munoz-Price LS,Fajardo-Aquino Y,Arheart KL

    更新日期:2012-02-01 00:00:00

  • Occupationally acquired human immunodeficiency virus (HIV) infection: national case surveillance data during 20 years of the HIV epidemic in the United States.

    abstract:OBJECTIVE:To characterize occupationally acquired human immunodeficiency virus (HIV) infection detected through case surveillance efforts in the United States. DESIGN:National surveillance systems, based on voluntary case reporting. SETTING:Healthcare or laboratory (clinical or research) settings. PATIENTS:Healthcar...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502178

    authors: Do AN,Ciesielski CA,Metler RP,Hammett TA,Li J,Fleming PL

    更新日期:2003-02-01 00:00:00

  • Quality assessment of hospital discharge database for routine surveillance of hip and knee arthroplasty-related infections.

    abstract:OBJECTIVE:Surgical site infection (SSI) surveillance represents a key method of nosocomial infection control programs worldwide. However, most SSI surveillance systems are considered to be poorly cost effective regarding human and economic resources required for data collection and patient follow up. This study aims to...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/676423

    authors: Grammatico-Guillon L,Baron S,Gaborit C,Rusch E,Astagneau P

    更新日期:2014-06-01 00:00:00

  • Infection related to implantable central venous access devices in cancer patients: epidemiology and risk factors.

    abstract:OBJECTIVE:To describe the epidemiology of infections related to the use of implantable central venous access devices (CVADs) in cancer patients and to evaluate measures aimed at reducing the rates of such infections. DESIGN:Prospective cohort study. SETTING:Referral hospital for cancer in São Paulo, Brazil. PATIENTS...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/671006

    authors: Freire MP,Pierrotti LC,Zerati AE,Araújo PH,Motta-Leal-Filho JM,Duarte LP,Ibrahim KY,Souza AA,Diz MP,Pereira J,Hoff PM,Abdala E

    更新日期:2013-07-01 00:00:00

  • The Likelihood of Hospital Readmission Among Patients With Hospital-Onset Central Line-Associated Bloodstream Infections.

    abstract:OBJECTIVE:To determine whether central line-associated bloodstream infections (CLABSIs) increase the likelihood of readmission. DESIGN:Retrospective matched cohort study for the years 2008-2009. SETTING:Acute care hospitals. PARTICIPANTS:Medicare recipients. CLABSI and readmission status were determined by linking N...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.115

    authors: Khong CJ,Baggs J,Kleinbaum D,Cochran R,Jernigan JA

    更新日期:2015-08-01 00:00:00

  • A qualitative assessment of a performance measure for reporting influenza vaccination rates among healthcare personnel.

    abstract::To understand the feasibility of implementing a standardized performance measure for collecting and reporting influenza vaccination rates among healthcare personnel, qualitative, semistructured interviews were conducted with key informants in 32 healthcare facilities. Despite practical and logistical challenges to imp...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/667375

    authors: Maccannell T,Shugart A,Schneider AK,Lindley MC,Lorick SA,Rao A,Woods LO,Ahmed F,Sinkowitz-Cochran RL

    更新日期:2012-09-01 00:00:00

  • Adverse effects of amantadine and oseltamivir used during respiratory outbreaks in a center for developmentally disabled adults.

    abstract:BACKGROUND AND OBJECTIVES:Antiviral prophylaxis is recommended for the control of institutional influenza A outbreaks. In long-term-care institutions other than nursing homes, neither the seriousness of influenza nor the risks and benefits of antiviral prophylaxis is clearly understood. We studied the severity of illne...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502326

    authors: McGeer AJ,Lee W,Loeb M,Simor AE,McArthur M,Green K,Benjamin JH,Gardner C

    更新日期:2004-11-01 00:00:00

  • Does the specific time of day used to capture data on ventilator-days have an impact on the documented rates of ventilator-associated pneumonia?

    abstract::Definitions of ventilator-associated pneumonia do not note a preferred daily time for obtaining denominator data. We examined collecting data on the number of ventilator-days at different times of day in 7 intensive care units. Rates of ventilator-associated pneumonia did not significantly differ when denominator data...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/652450

    authors: Talbot TR,Starmer JM

    更新日期:2010-05-01 00:00:00

  • Monitoring hand hygiene via human observers: how should we be sampling?

    abstract:OBJECTIVE:To explore how hand hygiene observer scheduling influences the number of events and unique individuals observed. DESIGN:We deployed a mobile sensor network to capture detailed movement data for 6 categories of healthcare workers over a 2-week period. SETTING:  University of Iowa Hospital and Clinic medical ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/666346

    authors: Fries J,Segre AM,Thomas G,Herman T,Ellingson K,Polgreen PM

    更新日期:2012-07-01 00:00:00

  • Interrepeat fingerprinting of third-generation cephalosporin-resistant Enterobacter cloacae isolated during an outbreak in a neonatal intensive care unit.

    abstract:OBJECTIVE:To investigate an outbreak in neonates of Enterobacter cloacae infection resistant to third-generation cephalosporins. DESIGN:A retrospective study of an outbreak in the neonatal intensive care unit (NICU) and review of E cloacae isolates in pediatric wards and other intensive care units from June 1992 throu...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646998

    authors: Verweij PE,Van Belkum A,Melchers WJ,Voss A,Hoogkamp-Korstanje JA,Meis JF

    更新日期:1995-01-01 00:00:00

  • Cost-effectiveness of hepatitis A vaccination in healthcare workers.

    abstract:OBJECTIVE:To study the cost-effectiveness of vaccination for hepatitis A. SETTING:Hypothetical analysis of students currently enrolled in medical school in the United States. METHOD:A Markov-based model was developed using data from the literature, actual hospital costs, and an annual discount rate of 5%. The inciden...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647513

    authors: Smith S,Weber S,Wiblin T,Nettleman M

    更新日期:1997-10-01 00:00:00

  • Cleaning and sterilization protocol for reused cardiac electrophysiology catheters inactivates hepatitis and coxsackie viruses.

    abstract:OBJECTIVE:To assess the efficacy of a standard cleaning and sterilization protocol employed during reuse of cardiac electrophysiology catheters on the infectivity of duck hepatitis B virus (DHBV; a surrogate for human hepatitis B virus), bovine viral diarrhea virus (BVDV; a surrogate for human hepatitis C virus), and h...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502609

    authors: Druce JD,Russell JS,Birch CJ,Vickery K,Harper RW,Smolich JJ

    更新日期:2005-08-01 00:00:00

  • Total duration of antimicrobial therapy resulting from inpatient hospitalization.

    abstract:OBJECTIVE:To assess the feasibility of electronic data capture of postdischarge durations and evaluate total durations of antimicrobial exposure related to inpatient hospital stays. DESIGN:Multicenter, retrospective cohort study. SETTING:Two community hospitals and 1 academic medical center. PATIENTS:Hospitalized pa...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1017/ice.2019.118

    authors: Dyer AP,Dodds Ashley E,Anderson DJ,Sarubbi C,Wrenn R,Hicks LA,Srinivasan A,Moehring RW

    更新日期:2019-08-01 00:00:00