Abstract:
OBJECTIVE:To determine the appropriateness of antibiotic prophylaxis regimens for major surgery in Korea. DESIGN:Retrospective study using a written survey for each patient who underwent arthroplasty, colon surgery, or hysterectomy. SETTING:Six tertiary hospitals in Seoul and Gyeonggi Province. PATIENTS:From each hospital, a maximum of 150 patients who underwent each type of surgery were randomly chosen for the study. RESULTS:Of 2,644 eligible patients, 1,914 patients were included in the analysis; 677 of these patients underwent arthroplasty, 578 underwent colon surgery, and 659 underwent hysterectomy. Nineteen patients were excluded from the analyses of the class and number of antibiotics used for prophylaxis because they underwent multiple surgeries at different sites. For each of the 1,895 remaining patients, antibiotic prophylaxis involved a mean (+/-SD) of 2.8 +/- 0.9 classes of antibiotics. The most commonly prescribed agents were cephalosporins (prescribed for 1,875 [98.9%] of the patients) and aminoglycosides (1,404 [74.1%]). A total of 1,574 (83.1%) of patients received at least 2 classes of antibiotics simultaneously. Only 15 (0.8%) of 1,895 patients received antibiotic prophylaxis in accordance with published guidelines. Of 506 patients for whom the initial dose of antibiotics was evaluated, 374 (73.9%) received an appropriate initial dose. Of the 1,676 patients whose medical records included information about antibiotic administration relative to the time of surgery, only 188 (11.2%) received antibiotic prophylaxis an hour or less before the surgical incision was made. Of the 1,748 patients whose medical records included information about duration of surgery, antibiotic prophylaxis was discontinued 24 hours or less after surgery for only 3 (0.2%) of the patients. CONCLUSION:Most patients who had major surgery in Korea received inappropriate antibiotic prophylaxis. Measures to improve the appropriateness of antibiotic prophylaxis are urgently required.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Choi WS,Song JY,Hwang JH,Kim NS,Cheong HJdoi
10.1086/519180subject
Has Abstractpub_date
2007-08-01 00:00:00pages
997-1002issue
8eissn
0899-823Xissn
1559-6834pii
ICHE2006392journal_volume
28pub_type
杂志文章abstract::Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 1...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.22
更新日期:2019-04-01 00:00:00
abstract::OBJECTIVE To evaluate the new adult Centers for Disease Control and Prevention (CDC) ventilator-associated event (VAE) module in critically ill children and compare with the traditionally used CDC definition for ventilator-associated pneumonia (VAP). DESIGN Retrospective observational study of mechanically ventilated ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.135
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Peripheral venous catheters (PVCs) can be associated with serious infectious complications. We evaluated the effect of education and feedback on process measures to improve PVC care and infectious complications. DESIGN:Quasi-experimental controlled crossover study with sampling before and aft...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1086/665322
更新日期:2012-05-01 00:00:00
abstract::During the last quarter century, numerous reports have indicated that antimicrobial resistance commonly is encountered in long-term-care facilities (LTCFs). Gram-negative uropathogens resistant to penicillin, cephalosporin, aminoglycoside, or fluoroquinolone antibiotics and methicillin-resistant Staphylococcus aureus ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/647257
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To determine the rates of surgical-site infections (SSIs) after spinal surgery and to identify the risk factors associated with infection. DESIGN:SSIs had been identified by active prospective surveillance. A case-control study to identify risk factors was performed retrospectively. SETTING:University-asso...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502259
更新日期:2003-08-01 00:00:00
abstract::Multiple cultures were positive for Bacillus cereus during routine quality assurance testing of a pharmacy robot that prepares intravenous medications. An investigation confirmed bacterial contamination of the robot as well as drug product made by the robot. The process and outcomes of the investigation are described ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/665316
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Describe the epidemiology of central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) participating in a standardized and mandatory CLABSI surveillance program. DESIGN:Retrospective cohort. Setting. We included patients admitted (April 2007-March 2011) to 7 level II/I...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/673464
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To describe factors associated with a rectal swab or stool sample positive for norovirus, rotavirus, or adenovirus. DESIGN:Retrospective study. SETTING:Charleston Area Medical Center, a regional academic medical center in Charleston, West Virginia. METHODS:Rectal swab or stool samples were obtained from pa...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/654004
更新日期:2010-08-01 00:00:00
abstract::Air conditioner condensates have not been previously associated with cases of Legionnaires' disease. We report the possible transmission of Legionella pneumophila serogroup 1 from a malfunctioning automobile air conditioning system's leaking water onto the floorboard of a car driven for a long distance by the patient....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502025
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:Laboratory-based characterization and traceback of Clostridium butyricum isolates linked to outbreak cases of neonatal necrotizing enterocolitis (NEC) in a hospital in China. METHODS:In total, 37 samples were collected during the NEC outbreak. Classical bacteriological methods were applied to isolate and ide...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.289
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To describe an outbreak of hepatitis C in a clinical research study. DESIGN:Observational study. SETTING:Tertiary-care hospital. PATIENTS:Healthcare workers who volunteered to be subjects in a study of the metabolic effects of inhaled and oral corticosteroids who were unwittingly exposed to hepatitis C vir...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501848
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:The National Nosocomial Infections Surveillance (NNIS) System personnel report trends in antimicrobial-resistant pathogens. To validate select antimicrobial susceptibility testing results and to identify test methods that tend to produce errors, we conducted proficiency testing among NNIS System hospital labo...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502214
更新日期:2003-05-01 00:00:00
abstract::OBJECTIVE To compare central line use and central line-associated bloodstream infection in newborn infants before and after the introduction of a central line infection prevention bundle in order to determine the effectiveness of the bundle and to identify areas for further improvement. DESIGN Retrospective cohort ana...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.127
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To explore how hand hygiene observer scheduling influences the number of events and unique individuals observed. DESIGN:We deployed a mobile sensor network to capture detailed movement data for 6 categories of healthcare workers over a 2-week period. SETTING: University of Iowa Hospital and Clinic medical ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/666346
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:In colorectal surgery, the composition of the most effective bundle for prevention of surgical site infections (SSI) remains uncertain. We performed a meta-analysis to identify bundle interventions most associated with SSI reduction. METHODS:We systematically reviewed 4 databases for studies that assessed bu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.112
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To determine trends, patient characteristics, and outcome of patients with healthcare-associated influenza in Canadian hospitals. DESIGN:Prospective surveillance of laboratory-confirmed influenza among hospitalized adults was conducted from 2006 to 2012. Adults with positive test results at or after admissio...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/674858
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Cohorting patients who are colonized or infected with multidrug-resistant organisms (MDROs) protects uncolonized patients from acquiring MDROs in healthcare settings. The potential for cross transmission within the cohort and the possibility of colonized patients acquiring secondary isolates with additional a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.261
更新日期:2020-10-01 00:00:00
abstract::OBJECTIVE To analyze influential infectious diseases, antimicrobial stewardship, infection control, or medical microbiology blogs and bloggers SETTING World wide web DESIGN We conducted a systematic search for blogs in accordance with the PRISMA guidelines in September 2015. METHODS A snowball sampling approach was ap...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.69
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To investigate whether rhinovirus infection leads to increased airborne dispersal of coagulase-negative staphylococci (CoNS). DESIGN:Prospective nonrandomized intervention trial. SETTING:Wake Forest University School of Medicine, Winston-Salem, North Carolina. PARTICIPANTS:Twelve nasal Staphylococcus aureu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502430
更新日期:2004-06-01 00:00:00
abstract::Group A streptococcus is an uncommon but important cause of nosocomial infections. Outbreaks of infection most often have occurred in surgical or obstetrical patients. We describe an outbreak of severe group A streptococcal infections that occurred on a medical unit of a community hospital. Within an 8-day period, thr...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647335
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:SARS-CoV-2 has been implicated in the largest recorded coronavirus outbreak to date. Initially, most COVID-19 cases were in China, but the virus has spread to more than 184 countries worldwide, and the United States currently has more cases than any other country. OBJECTIVE:With person-to-person spread expa...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.218
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Bloodstream infections due to methicillin-resistant Staphylococcus aureus (MRSA) have been associated with significant risk of in-hospital mortality. The acute physiology and chronic health evaluation (APACHE) II score was developed and validated for use among intensive care unit (ICU) patients, but its utili...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/665731
更新日期:2012-06-01 00:00:00
abstract::Malassezia furfur, a lipophilic yeast, has become recognized as a cause of sepsis in infants receiving parenteral fat emulsions via indwelling deep venous catheters. Colonization of infants' skin may be a prerequisite to colonization of the intravascular catheter and subsequent infection with M furfur. Three hundred n...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645819
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:To determine the impact of the introduction of a plastic shield-shaped device (Needleguard, Biosafe, Auckland, New Zealand) and education program designed to allow safer recapping, on recorded rates of needlestick injury. DESIGN:A before-after trial with a two-year duration of follow-up. SETTING:Tertiary re...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646328
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVE:To elucidate behavioral determinants of handwashing among nurses. DESIGN:Statistical modeling using the Theory of Planned Behavior and relevant components to handwashing behavior by nurses that were derived from focus-group discussions and literature review. SETTING:The community and 3 tertiary care hospita...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/503335
更新日期:2006-05-01 00:00:00
abstract::US hospitals are engaged in an infection control arms race. Hospitals, specialties, and professional groups are spurring one another on to adopt progressively more aggressive measures in response to COVID-19 that often exceed federal and international standards. Examples include universal masking of providers and pati...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.211
更新日期:2020-11-01 00:00:00
abstract::Storage cabinets for heat-sensitive endoscopes (SCHEs) are designed to store gastrointestinal (GI) endoscopes in a clean, dry and well-ventilated cupboard to prevent microbiological proliferation. The use of SCHEs in a GI endoscopy unit has significally reduced the rate of contaminated endoscopes (13.0% vs 45.0%, P<.0...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.139
更新日期:2015-09-01 00:00:00
abstract::In a hospital in Lima, Peru, a review of 103 Staphylococcus aureus infections was conducted during 2002. The prevalence of oxacillin-resistant S. aureus strains was 68%; 25% of strains were resistant to multiple drugs. Previous use of antibiotics and undergoing a surgical procedure during the current hospital stay wer...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/500650
更新日期:2006-02-01 00:00:00
abstract:UNLABELLED:OBJECTIVE. To determine the impact of known observers on hand hygiene performance in inpatient care units with differing baseline levels of hand hygiene compliance. DESIGN:Observational study. SETTING:Three inpatient care units, selected on the basis of past hand hygiene performance, in a hospital where ha...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/595692
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly emerging worldwide. Control group selection is critically important when analyzing predictors of antimicrobial resistance. Focusing on modifiable risk factors can optimize prevention and resource expenditures. To identify specific predictors of CRE, p...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/666642
更新日期:2012-08-01 00:00:00