Abstract：
OBJECTIVE:Describe the epidemiology of central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) participating in a standardized and mandatory CLABSI surveillance program. DESIGN:Retrospective cohort. Setting. We included patients admitted (April 2007-March 2011) to 7 level II/III NICUs who developed a CLABSI (as defined by the National Healthcare Safety Network). METHODS:CLABSIs/1,000 central line-days and device utilization ratio were calculated; χ(2) test, Student t test, Kruskal-Wallis, and Poisson regression were used. RESULTS:Overall, 191 patients had 202 CLABSI episodes for a pooled mean rate of 4.0 CLABSIs/1,000 central line-days and a device utilization ratio of 0.20. Annual pooled mean CLABSI rates increased from 3.6 in 2007-2008 to 5.1 CLABSIs/1,000 central line-days in 2010-2011 (P - .01). The all-cause 30-day case fatality proportion was 8.9% (n = 17) and occurred a median of 8 days after CLABSI. Coagulase-negative Staphylococcus was identified in 112 (50.5%) cases. Staphylococcus aureus was identified in 22 cases, and 3 (13.6%) were resistant to methicillin. An underlying intra-abdominal pathology was found in 20% (40/202) of CLABSI cases, 50% of which were reported in the last year of study. When adjusted for mean birth weight, annual CLABSI incidence rates were independently associated with the proportion of intra-abdominal pathology (P = .007) and the proportion of pulmonary pathology (P = .016) reported. CONCLUSION:The increase in CLABSI rates in Quebec NICUs seems to be associated with an increased proportion of cases with underlying intra-abdominal and pulmonary pathologies, which needs further investigation.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Blanchard AC,Fortin E,Rocher I,Moore DL,Frenette C,Tremblay C,Quach Cdoi
10.1086/673464subject
Has Abstractpub_date
2013-11-01 00:00:00pages
1167-73issue
11eissn
0899-823Xissn
1559-6834pii
S0195941700034184journal_volume
34pub_type
杂志文章abstract：OBJECTIVE:To investigate a possible nosocomial outbreak of tuberculosis (TB). DESIGN:Retrospective cohort study. SETTING:Community hospital. METHODS:We reviewed medical records, hospital infection control measures, and potential locations of nosocomial exposure. We examined the results of acid-fast bacilli (AFB) sme...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/502144
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:To determine the attributable risk of death due to catheter-related septicemia (CRS) in critically ill patients when taking into account severity of illness during the intensive-care unit (ICU) stay but before CRS. DESIGN:Pairwise-matched (1:2) exposed-unexposed study. SETTING:10-bed medical-surgical ICU an...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/501639
更新日期：1999-06-01 00:00:00
abstract：:OBJECTIVE Contaminated hands of healthcare workers (HCWs) are an important source of transmission of healthcare-associated infections. Alcohol-based hand sanitizers, while effective, do not provide sustained antimicrobial activity. The objective of this study was to compare the immediate and persistent activity of 2 h...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,随机对照试验
doi：10.1017/ice.2017.293
更新日期：2018-03-01 00:00:00
abstract：:We analyzed California hospitals' National Healthcare Safety Network Annual Surveys to describe antimicrobial stewardship program (ASP) implementation progress following new state ASP legislation. The proportion of hospitals with all 7 Core Elements of Hospital ASP rose from 59.3% in 2014 to 69.2% in 2015 (P<.001). In...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1017/ice.2017.218
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Clostridium difficile is a major cause of infectious diarrhea in hospitalized patients. Between August 2003 and January 2004, we experienced an increase in the incidence of C. difficile-associated disease. We describe the investigation into and management of the outbreak in this article. METHODS:A total of ...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/519181
更新日期：2007-08-01 00:00:00
abstract：OBJECTIVE:To investigate the possibility that contaminated commercial activated charcoal may serve as a source for fungal colonization or infection of the lower respiratory tract. DESIGN:The clinical course of a patient who aspirated commercial activated charcoal was reviewed. Fungal cultures were performed for 2 samp...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/646281
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVE:To determine whether the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) Clostridioides difficile infection (CDI) severity criteria adequately predicts poor outcomes. DESIGN:Retrospective validation study. SETTING AND PARTICIPANTS:Patients with CDI...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1017/ice.2020.8
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To confirm the vertical transmission of Citrobacter diversus from a mother to her infant and to evaluate the epidemiologic usefulness of a new automated procedure for analysis of polymerase chain reaction (PCR)-generated DNA fingerprints. DESIGN:Repetitive element-based PCR (rep-PCR) analysis of C diversus i...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/647009
更新日期：1995-10-01 00:00:00
abstract：:Because the severe acute respiratory syndrome (SARS) outbreak in Taiwan in 2003 was worsened by hospital infections, we analyzed 229 questionnaires (84.8% of 270 sent) completed by surveyed healthcare workers who cared for patients with SARS in 3 types of hospitals, to identify surveillance problems. Atypical clinical...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/508835
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To describe factors associated with a rectal swab or stool sample positive for norovirus, rotavirus, or adenovirus. DESIGN:Retrospective study. SETTING:Charleston Area Medical Center, a regional academic medical center in Charleston, West Virginia. METHODS:Rectal swab or stool samples were obtained from pa...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/654004
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:The quality of environmental hygiene in hospitals is under increasing scrutiny from both healthcare providers and consumers because the prevalence of serious infections due to multidrug-resistant pathogens has reached alarming levels. On the basis of the results from a small number of hospitals, we undertook ...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1086/524329
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:To determine the prevalence and incidence of methicillin-resistant Staphylococcus aureus (MRSA) colonization among residents and healthcare workers (HCWs) of a long-term-care facility (LTCF), to assess possible routes of nosocomial spread, and to determine genetic relatedness of the isolates. SETTING:A 351-...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/502524
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVES:To measure the incidence of nosocomial infection (NI) among patients with septic shock according to the place of septic shock acquisition and to evaluate the increase in the risk of pulmonary infection associated with septic shock. DESIGN:Prospective cohort study. SETTING:Two intensive care units (ICUs) of...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/591859
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To review the current recommendations for immunoprophylaxis and chemoprophylaxis of infection in adults, including those who are at increased risk from occupation, lifestyle, travel, or pre-existing medical conditions. DESIGN:Review of the pertinent literature. SETTING:Adult ambulatory care. CONCLUSIONS:Gu...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,评审
doi：10.1086/646526
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:To study the spread of strains of Enterobacter aerogenes in our hospital in 1992 and 1993 by using two genotypic markers, and to evaluate these methods for the epidemiological investigation of this species. DESIGN:Ribotyping (using two endonucleases) and arbitrarily primed (AP)-PCR (using two different 10-me...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/647094
更新日期：1995-04-01 00:00:00
abstract：:We report the case of a pediatrician who developed meningococcal meningitis after performing endotracheal intubation without protection on a child who was suspected of having meningoencephalitis. This case emphasizes the necessity for healthcare workers who perform high-risk procedures to use personal protection devic...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/501672
更新日期：1999-08-01 00:00:00
abstract：:The prevalence of latent tuberculosis infection in a cohort of nurses new to a London hospital was 7.6% (13 of 171), using an interferon-gamma (IFN-gamma) release assay, and 16.2% (24 of 148), using the tuberculin skin test. On multivariate analysis, birth in a country with tuberculosis prevalence of more than 40 case...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/597546
更新日期：2009-06-01 00:00:00
abstract：:Observational studies compare outcomes among subjects with and without an exposure of interest, without intervention from study investigators. Observational studies can be designed as a prospective or retrospective cohort study or as a case-control study. In healthcare epidemiology, these observational studies often t...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,评审
doi：10.1017/ice.2016.118
更新日期：2016-10-01 00:00:00
abstract：:Micrococcus bacteria are frequently isolated from blood cultures and could represent a cause of infections associated with medical devices, particularly in immunocompromised patients; however, there is a lack of information on the management of micrococcal bacteremia. We report what is, to our knowledge, the largest s...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/592705
更新日期：2009-01-01 00:00:00
abstract：:Three different sequentially applied post-varicella zoster virus (VZV) exposure management strategies were employed over a 43-month period. We began by using a standard post-exposure protocol in which 50 susceptible healthcare workers (HCW) involved in hospital exposures were furloughed from work at a loss to the hosp...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/646176
更新日期：1990-06-01 00:00:00
abstract：OBJECTIVE:To assess the feasibility of electronic data capture of postdischarge durations and evaluate total durations of antimicrobial exposure related to inpatient hospital stays. DESIGN:Multicenter, retrospective cohort study. SETTING:Two community hospitals and 1 academic medical center. PATIENTS:Hospitalized pa...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1017/ice.2019.118
更新日期：2019-08-01 00:00:00
abstract：:Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 1...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1017/ice.2019.22
更新日期：2019-04-01 00:00:00
abstract：:If you have calculated a confidence interval for an infection rate and found the interval extending into meaningless negative numbers, chances are the error is due to use of approximation formulae. Many of us unknowingly were taught to use the Wald approximation, which does not always approximate the exact binomial di...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/501701
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To describe the identification, management, and clinical characteristics of hospitalized patients with influenza-like illness (ILI) during the peak period of activity of the 2009 pandemic strain of influenza A virus subtype H1N1 (2009 H1N1). DESIGN:Retrospective review of electronic medical records. PATIENT...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1086/661912
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To study risk factors for the highly variable local colonization rates with unrelated Enterobacter species strains previously found in 22 Swedish neonatal units (0% to 32.4% of the infants). PATIENTS AND SETTING:The fecal Enterobacter species carriage rates among 953 infants in the 22 special-care neonatal u...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/646641
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVE:To assess the time-dependent exposure of California healthcare facilities to patients harboring methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, and Clostridium difficile infec...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1017/ice.2015.181
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To describe the epidemiology and the interventions used to control two methicillin-resistant Staphylococcus aureus (MRSA) epidemics involving 46 infants with two fatalities in a neonatal intensive care unit (NICU). SETTING:A 50-bed, level III NICU in a university hospital. INTERVENTIONS:After traditional in...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/647285
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:To determine the impact of the introduction of a plastic shield-shaped device (Needleguard, Biosafe, Auckland, New Zealand) and education program designed to allow safer recapping, on recorded rates of needlestick injury. DESIGN:A before-after trial with a two-year duration of follow-up. SETTING:Tertiary re...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/646328
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVE:To investigate trends in plasmid types of methicillin-resistant Staphylococcus aureus over a 3-year period and determine the clinical impact of plasmid typing. DESIGN:Restriction endonuclease analysis of plasmid DNA (REAP) was used to type 270 clinical isolates. SETTING:A Veterans Affairs Medical Center. R...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/646627
更新日期：1993-01-01 00:00:00
abstract：:The extent to which the use of alcohol-based handrub for hand hygiene has been adopted by US hospitals is unknown. A survey of infection control coordinators (response rate, 516 [72%] of 719) revealed that most hospitals (436 [84%] of 516) have adopted alcohol-based handrub. Leadership support and staff receptivity pl...
journal_title：Infection control and hospital epidemiology
pub_type： 杂志文章
doi：10.1086/592095
更新日期：2008-12-01 00:00:00
