Abstract:
:OBJECTIVE To compare central line use and central line-associated bloodstream infection in newborn infants before and after the introduction of a central line infection prevention bundle in order to determine the effectiveness of the bundle and to identify areas for further improvement. DESIGN Retrospective cohort analysis of prospectively collected data. SETTING Level 5 neonatal intensive care unit in Sydney, Australia. PATIENTS Newborn infants admitted to the Royal Prince Alfred Hospital Neonatal Intensive Care Unit who had a central venous catheter (CVC) inserted. METHODS Data regarding clinical characteristics, CVC use, and infection were collected before and after the introduction of a bundle of interventions. The bundles encompassed (1) insertion of CVC, (2) maintenance of CVC, (3) an education program, and (4) ongoing surveillance and feedback. RESULTS Baseline and intervention groups were comparable in clinical characteristics. The number of CVCs inserted was reduced in the intervention group (central line utilization rate, 0.16 vs 0.2, P<.0001). Overall CVC dwell time was reduced, resulting from significant reduction in peripherally inserted CVC dwell time (6 days [95% CI, 5.0-11.8 days] vs 7.3 days [4.0-10.4 days], P=.0004). Central line-associated bloodstream infections were significantly reduced, predominantly secondary to decreased peripherally inserted CVC-related bloodstream infections (1.2/1,000 central line-days vs 11.5/1,000 central line-days, P<.0001). CONCLUSION This central line infection bundle was effective in reducing CVC use, dwell time, and central line-associated bloodstream infections. Infect Control Hosp Epidemiol 2016;37:1029-1036.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
McMullan R,Gordon Adoi
10.1017/ice.2016.127subject
Has Abstractpub_date
2016-09-01 00:00:00pages
1029-36issue
9eissn
0899-823Xissn
1559-6834pii
S0899823X16001276journal_volume
37pub_type
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journal_title:Infection control and hospital epidemiology
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
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journal_title:Infection control and hospital epidemiology
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更新日期:2014-01-01 00:00:00
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journal_title:Infection control and hospital epidemiology
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更新日期:2010-01-01 00:00:00
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更新日期:2003-07-01 00:00:00
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更新日期:2001-11-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/678069
更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/ice.2016.59
更新日期:2016-07-01 00:00:00
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doi:10.1086/647142
更新日期:1995-07-01 00:00:00
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doi:10.1086/646328
更新日期:1991-04-01 00:00:00
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更新日期:2004-03-01 00:00:00
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更新日期:1996-09-01 00:00:00
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更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1086/502514
更新日期:2005-02-01 00:00:00
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更新日期:2017-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1086/502326
更新日期:2004-11-01 00:00:00