Abstract:
OBJECTIVE:The National Nosocomial Infections Surveillance (NNIS) System personnel report trends in antimicrobial-resistant pathogens. To validate select antimicrobial susceptibility testing results and to identify test methods that tend to produce errors, we conducted proficiency testing among NNIS System hospital laboratories. SETTING:NNIS System hospital laboratories in the United States. METHODS:Each laboratory received five organisms (ie, an imipenem-resistant Serratia marcescens, an oxacillin-resistant Staphylococcus aureus, a vancomycin-resistant Enterococcus faecalis, a vancomycin-intermediate Staphylococcus epidermidis, and an extended-spectrum beta-lactamase (ESbetaL)-producing Klebsiella pneumoniae). Testing results were compared with reference testing results from the Centers for Disease Control and Prevention. RESULTS:Of 138 laboratories testing imipenem against the Serratia marcescens strain, 110 (80%) correctly reported minimum inhibitory concentrations (MICs) or zone sizes in the resistant range. All 193 participating laboratories correctly reported the Staphylococcus aureus strain as oxacillin resistant Of the 193 laboratories, 169 (88%) reported correct MICs or zone sizes for the vancomycin-resistant Enterococcus faecalis. One hundred sixty-two (84%) of 193 laboratories demonstrated the ability to detect a vancomycin-intermediate strain of Staphylococcus epidermidis, however, disk diffusion performed poorly when testing both staphylococci and enterococci with vancomycin. Although laboratory personnel correctly reported nonsusceptible extended-spectrum cephalosporins and aztreonam results for K. pneumoniae, only 98 (51%) of 193 correctly reported this organism as an ESbetaL producer. CONCLUSION:Overall, NNIS System hospital laboratory personnel detected most emerging resistance patterns. Disk diffusion continues to be unreliable for vancomycin testing of staphylococci and must be used cautiously for enterococci. Further education on the processing of ESbetaL-producing organisms is warranted.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Hageman JC,Fridkin SK,Mohammed JM,Steward CD,Gaynes RP,Tenover FC,National Nosocomial Infections Surveillance System Hospitals.doi
10.1086/502214subject
Has Abstractpub_date
2003-05-01 00:00:00pages
356-61issue
5eissn
0899-823Xissn
1559-6834pii
ICHE5375journal_volume
24pub_type
杂志文章abstract:OBJECTIVE:Antibiotic time-outs (ATOs) have been advocated to improve antibiotic use without dedicated stewardship resources, but their utility is poorly defined. We sought to evaluate the effectiveness of an ATO led by a team-based pharmacist. DESIGN:Cluster randomized controlled trial. SETTING:Six medicine teams at ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.347
更新日期:2020-11-01 00:00:00
abstract::We describe an outbreak of Pseudomonas aeruginosa respiratory tract infections related to intrinsically contaminated ultrasound gel used for intraoperative transesophageal echocardiograms in cardiovascular surgery patients. This investigation led to a product safety alert by the Food and Drug Administration and the de...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/671268
更新日期:2013-08-01 00:00:00
abstract::Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized ins...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.64
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of an active surveillance program for Staphylococcus aureus linked to a decolonization protocol on the incidence of healthcare-associated infection and new nasal colonization due to S. aureus. DESIGN:Retrospective quasi-experimental study. SETTING:An 18-bed medical intensive care uni...
journal_title:Infection control and hospital epidemiology
pub_type: 评论,杂志文章
doi:10.1086/654001
更新日期:2010-08-01 00:00:00
abstract::We evaluated vancomycin use in a hospital with endemic vancomycin-resistant enterococci and a vancomycin restriction program. Only 68% of vancomycin was prescribed appropriately. Inappropriate use was due primarily to empirical therapy. In the patients with a microbiological diagnosis following empirical therapy, 83% ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501548
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To determine the influence of catheter site and type (single- vs triple-lumen) on infection rates associated with central venous catheterization. DESIGN:Prospective observational study of all nontunneled central venous catheters over a 28-month period. Data collected included patient characteristics, inserti...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647742
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of a multifaceted hospitalwide quality improvement program that featured an intervention to remind physicians to remove unnecessary urinary catheters. METHODS:A hospitalwide preintervention-postintervention study was conducted over 2 years (July 1, 2004, through June 30, 2006). The i...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/518453
更新日期:2007-07-01 00:00:00
abstract::OBJECTIVE Clostridium difficile infection (CDI) is a common hospital-acquired infection. Previous reports on the incidence, risk factors, and impact of CDI on resources in the surgical population are limited. In this context, we study CDI across diverse surgical settings. METHODS We prospectively identified patients w...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2014.8
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To determine risk factors for ceftazidime-resistant Klebsiella pneumoniae infection and the effect of ceftazidime-resistant K. pneumoniae infection on mortality during an isolated outbreak. DESIGN:Case-control investigation using clinical and molecular epidemiology and prospective analysis of infection cont...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502488
更新日期:2005-01-01 00:00:00
abstract::Nine hundred sixteen cultures were obtained from homes of patients with cystic fibrosis, control homes, salad bars, and food markets, and analyzed for the presence of Pseudomonas cepacia and related bacteria. P cepacia was recovered from 5 (18%) of 27 homes, and from 20 (4%) of 509 cultures collected outside of homes....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646999
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of a new monochloramine generation system for control of Legionella in a hospital hot water distribution system. SETTING:A 495-bed tertiary care hospital in Pittsburgh, Pennsylvania. The hospital has 12 floors covering approximately 78,000 m(2). METHODS:The hospital hot water system...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/678418
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To assess definitions, experience, and infection control practices for multidrug-resistant gram-negative bacteria (MDR-GNB), including Enterobacteriaceae, Acinetobacter, and Pseudomonas species, in acute care hospitals. DESIGN:Cross-sectional survey. PARTICIPANTS:US and international members of the Society ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/675600
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To analyze the secular trends of candidemia in a large tertiary-care hospital to determine the overall incidence, as well as the incidence by ward and by species, and to detect the occurrence of outbreaks. DESIGN:Retrospective descriptive analysis. Secular trends were calculated using the Mantel-Haenszel tes...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502582
更新日期:2005-06-01 00:00:00
abstract::We present basic information that a hospital epidemiologist needs when designing a surveillance system for noninfectious adverse outcomes of care. Specific topics reflect key characteristics of such a surveillance system: the purpose, rationale, priorities, definitions, data collection tools, data collection, analysis...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647142
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:Describe the clinical and molecular epidemiology of incident Clostridium difficile infection (CDI) cases in Chicago area acute healthcare facilities (HCFs). DESIGN AND SETTING:Laboratory, clinical, and epidemiologic information was collected for patients with incident CDI who were admitted to acute HCFs in F...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/661283
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To estimate the incidence of methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized in French public hospitals. DESIGN:A 2-month survey that included 163,573 patients and 140,114 admissions. SETTING AND PATIENTS:Forty-three public or public-affiliated hospitals throughout France, includ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501656
更新日期:1999-07-01 00:00:00
abstract::OBJECTIVE To describe the investigation and control of a cluster of Serratia marcescens bacteremia in a 505-bed tertiary-care center. METHODS Cluster cases were defined as all patients with S. marcescens bacteremia between March 2 and April 7, 2014, who were found to have identical or related blood isolates determined...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.137
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To determine the rates of and risk factors for carriage and acquisition of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae during hospitalization. DESIGN:Cohort study. SETTING:Shaare Zedek Medical Center, a 550-bed teaching hospital. METHODS:During a 5-month period (February 1-June 30,...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597505
更新日期:2009-06-01 00:00:00
abstract::Definitions of ventilator-associated pneumonia do not note a preferred daily time for obtaining denominator data. We examined collecting data on the number of ventilator-days at different times of day in 7 intensive care units. Rates of ventilator-associated pneumonia did not significantly differ when denominator data...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/652450
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:The molecular epidemiology of pediatric Clostridium difficile infection (CDI) is poorly understood. We aimed to identify the restriction endonuclease analysis (REA) groups causing CDI and to determine risk factors and outcomes associated with CDI caused by epidemic strains in children. DESIGN:Retrospective c...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2014.89
更新日期:2015-04-01 00:00:00
abstract::OBJECTIVE To summarize and discuss logistic and administrative challenges we encountered during the Benefits of Enhanced Terminal Room (BETR) Disinfection Study and lessons learned that are pertinent to future utilization of ultraviolet (UV) disinfection devices in other hospitals DESIGN Multicenter cluster randomized...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1017/ice.2017.268
更新日期:2018-02-01 00:00:00
abstract::OBJECTIVE To determine whether the use of enhanced isolation precautions (droplet and contact precautions) for inpatients with respiratory tract viral infections is associated with a reduction in rate of nosocomial viral respiratory infections. DESIGN Quasi-experimental study with the rate of nosocomial respiratory vi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.282
更新日期:2018-02-01 00:00:00
abstract::We report the effect of prospective audit and feedback (PAF) on inpatient fluoroquinolone (FQN) prescriptions. During the PAF period, FQN use decreased from 39.19 to 29.58 days of therapy per 1,000 patient days (P < .001) and appropriateness improved from 68% to 88% (P < .001). High-yield indications to target include...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.339
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To report the International Nosocomial Infection Control Consortium surveillance data from 40 hospitals (20 cities) in India 2004-2013. METHODS:Surveillance using US National Healthcare Safety Network's criteria and definitions, and International Nosocomial Infection Control Consortium methodology. RESULTS:...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.276
更新日期:2016-02-01 00:00:00
abstract::We describe the high burden of carbapenemase-producing Enterobacteriaceae (CPE) colonization and infection in a neuro-rehabilitation hospital in Italy over a 6-year period. Overall, 9.3% of patients were found to be CPE carriers on admission; the rates of CPE in-hospital acquisition and CPE-BSI were 9.2 and 2.9 cases ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.344
更新日期:2019-03-01 00:00:00
abstract::We assessed the rate of recovery of fluoroquinolone-resistant and fluoroquinolone-susceptible Escherichia coli isolates from culture of frozen perirectal swab samples compared with the results for culture of the same specimen before freezing. Recovery rates for these 2 classes of E. coli were 91% and 83%, respectively...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/529590
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To investigate an outbreak in neonates of Enterobacter cloacae infection resistant to third-generation cephalosporins. DESIGN:A retrospective study of an outbreak in the neonatal intensive care unit (NICU) and review of E cloacae isolates in pediatric wards and other intensive care units from June 1992 throu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646998
更新日期:1995-01-01 00:00:00
abstract::Intracavity ultrasound transducer handles are not routinely immersed in liquid high-level disinfectants. We show that residual bacteria, including pathogens, persist on more than 80% of handles that are not disinfected, whereas use of an automated device reduces contamination to background levels. Clinical staff shoul...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.12
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:Few data are available on methicillin-resistant Staphylococcus aureus (MRSA) colonization in day care. We performed a study in a medical university child care center to study the epidemiology of MRSA in this population. DESIGN:Survey. SETTING:A child care center on the campus of a university medical center....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605721
更新日期:2009-10-01 00:00:00
abstract::BACKGROUND Healthcare provider hands are an important source of intraoperative bacterial transmission events associated with postoperative infection development. OBJECTIVE To explore the efficacy of a novel hand hygiene improvement system leveraging provider proximity and individual and group performance feedback in r...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/ice.2016.106
更新日期:2016-08-01 00:00:00