当前位置： SCI文献检索 > INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY期刊下所有文献 > Risk factors for epidemic Xanthomonas maltophilia infection/colonization in intensive care unit patients.

Risk factors for epidemic Xanthomonas maltophilia infection/colonization in intensive care unit patients.

Abstract：

OBJECTIVE:To determine risk factors for and modes of transmission of Xanthomonas maltophilia infection/colonization. DESIGN:Surveillance and cohort study. SETTING:A 470-bed tertiary trauma-referral community hospital. PATIENTS:From January 1, 1988 to March 17, 1989, 106 intensive care unit patients developed X maltophilia infection/colonization. We defined a case as any intensive care unit patient who, from July 15, 1988, through March 17, 1989 (epidemic period), had X maltophilia infection/colonization greater than or equal to 48 hours after intensive care unit admission. We identified 45 case patients and 103 control patients (persons in the shock-trauma intensive care unit for greater than or equal to 72 hours during the epidemic period who had no X maltophilia-positive culture). RESULTS:Cases were significantly more likely to occur in the shock-trauma intensive care unit than in all other intensive care units combined. Mechanical ventilation, tracheostomy, being transported to the hospital by airplane, and receipt of a higher mean number of antimicrobials were risk factors for X maltophilia infection/colonization. Risk of X maltophilia infection/colonization was significantly greater among cases exposed to a patient with a X maltophilia surgical wound infection than among those without such exposure (relative risk = 1.3, p = .03). Animate and inanimate cultures revealed X maltophilia contamination of the hospital room of a patient with an X maltophilia surgical wound infection, of respiratory therapy equipment in this patient's room, of respirometers shared between patients, and of shock-trauma intensive care unit personnel's hands. Related environmental and clinical isolates were serotype 10. CONCLUSIONS:Mechanically ventilated patients receiving antimicrobials in the shock-trauma intensive care unit were at increased risk of X maltophilia infection/colonization. Patients with draining X maltophilia surgical wound infections served as reservoirs for X maltophilia, and contamination of the respirometers and the hands of shock-trauma intensive care unit personnel resulted in patient-to-patient transmission of X maltophilia.

journal_name

Infect Control Hosp Epidemiol

journal_title

Infection control and hospital epidemiology

authors

Villarino ME,Stevens LE,Schable B,Mayers G,Miller JM,Burke JP,Jarvis WR

doi

10.1086/646510

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

201-6

issue

eissn

0899-823X

issn

1559-6834

journal_volume

pub_type

杂志文章

在线工具

Risk factors for epidemic Xanthomonas maltophilia infection/colonization in intensive care unit patients.