Abstract:
OBJECTIVE:To investigate and determine the cause of an outbreak of Mycobacterium mucogenicum bacteremias in bone marrow transplant (BMT) and oncology patients. DESIGN:Case-control study and culturing of hospital water sources. Isolates were typed using molecular methods. SETTING:University-affiliated, tertiary-care medical center. PATIENTS:Case-patients were adult and pediatric BMT patients or hematopoietic stem cell transplant (BMT) (n = 5) and oncology (n = 1) patients who were diagnosed as having M. mucogenicum bacteremia during the study period of August through November 1998. Two control-patients were selected for each case-patient matched by age, time of hospitalization, inpatient unit, and type of patient (BMT or oncology). RESULTS:There were no significant differences between case-patients and control-patients regarding intravenous products received or procedures performed, frequency of bathing, neutropenia, or steroid use. Nontuberculous mycobacteria were isolated from several water sources at the medical center including tap water from sinks and showerheads, the hospital hot water source, and the city water supply to the hospital. Analysis by multilocus enzyme electrophoresis and randomly amplified polymorphic DNA showed a match between one patient's blood isolate and an isolate from shower water from that patient's prior hospital room. CONCLUSIONS:The cause of the outbreak seemed to be water contamination of central venous catheters (CVCs) during bathing. A recommendation in early 2001 that CVCs be protected from water during bathing was followed by no M. mucogenicum bacteremias during the second half of 2001, only one in 2002, and none at all during 2003.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Kline S,Cameron S,Streifel A,Yakrus MA,Kairis F,Peacock K,Besser J,Cooksey RCdoi
10.1086/502341subject
Has Abstractpub_date
2004-12-01 00:00:00pages
1042-9issue
12eissn
0899-823Xissn
1559-6834pii
S0195941700077432journal_volume
25pub_type
杂志文章abstract:BACKGROUND:States, including Illinois, have passed legislation mandating the use of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for reporting healthcare-associated infections, such as methicillin-resistant Staphylococcus aureus (MRSA). OBJECTIVE:To evaluate the sens...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/651665
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To determine the safety and cost-effectiveness of replacing the intravenous (IV) tubing sets in hospitalized patients at 4- to 7-day intervals instead of every 72 hours. DESIGN:Prospective, randomized study of infusion-related contamination associated with changing IV tubing sets within 3 days versus within ...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1086/501879
更新日期:2001-03-01 00:00:00
abstract::Vancomycin is a commonly prescribed empiric antibiotic used when methicillin-resistant Staphylococcus aureus (MRSA) infection is suspected. In this study, we aimed to determine the rate of culture-positive infection requiring vancomycin therapy. ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.123
更新日期:2018-08-01 00:00:00
abstract::Typing systems for differentiating among strains of methicillin-resistant Staphylococcus aureus (MRSA) can be valuable tools for the epidemiologist and the clinician. Specific criteria for evaluating such systems are typeability, reproducibility, and discriminatory power. An ideal typing system also would be rapid, in...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646234
更新日期:1991-01-01 00:00:00
abstract::Malassezia furfur, a lipophilic yeast, has become recognized as a cause of sepsis in infants receiving parenteral fat emulsions via indwelling deep venous catheters. Colonization of infants' skin may be a prerequisite to colonization of the intravascular catheter and subsequent infection with M furfur. Three hundred n...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645819
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:To estimate the incidence of methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized in French public hospitals. DESIGN:A 2-month survey that included 163,573 patients and 140,114 admissions. SETTING AND PATIENTS:Forty-three public or public-affiliated hospitals throughout France, includ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501656
更新日期:1999-07-01 00:00:00
abstract::With use of the Nationwide Inpatient Sample, we conducted a study to determine whether rates of Clostridium difficile infection for delivery-associated hospitalizations are increasing. From 1998 to 2006, the number and incidence of C. difficile infection among peripartum women increased significantly. These increases ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/652454
更新日期:2010-05-01 00:00:00
abstract::We report the case of a pediatrician who developed meningococcal meningitis after performing endotracheal intubation without protection on a child who was suspected of having meningoencephalitis. This case emphasizes the necessity for healthcare workers who perform high-risk procedures to use personal protection devic...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501672
更新日期:1999-08-01 00:00:00
abstract::An anonymous national survey of a representative population of healthcare workers who were thought likely to have frequent and intensive exposures to blood and other body fluids (certified nurse-midwives [CNMs]), was conducted to assess the type and frequency of self-reported occupational exposures to blood and body f...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646186
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:To identify delayed prophylaxis from a pre-existing database and strategies to improve performance. SETTING:A skilled nursing facility with 14 floors (4 buildings). The "outbreak unit" was a 50- to 60-bed floor. METHODS:We performed surveillance during six seasons using one protocol. Prophylaxis was started...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501978
更新日期:2002-10-01 00:00:00
abstract::During the closing years of the 20th century, there has been an unprecedented number of newly recognized infectious agents and a resurgence of infectious diseases only recently thought to be conquered. These problems have been compounded by the increasing number of pathogens that have evolved resistance to antimicrobi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/647347
更新日期:1996-08-01 00:00:00
abstract::The technology of intravenous catheter access ports has evolved from open ports covered by removable caps to more-sophisticated, closed versions containing mechanical valves. We report a significant increase in catheter-related bloodstream infections after the introduction of a new needle-free positive-pressure mechan...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/499166
更新日期:2006-01-01 00:00:00
abstract::Antibiotic prescribing practices across the Veterans' Health Administration (VA) experienced significant shifts during the coronavirus disease 2019 (COVID-19) pandemic. From 2015 to 2019, antibiotic use between January and May decreased from 638 to 602 days of therapy (DOT) per 1,000 days present (DP), while the corre...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1277
更新日期:2020-10-20 00:00:00
abstract:OBJECTIVE:To describe the epidemiology and spread of methicillin-resistant Staphylococcus aureus (MRSA) in three tertiary-care centers in Ottawa, Ontario, Canada, where MRSA is encountered infrequently. DESIGN:Retrospective review over a 6-year period, from January 1, 1990, through December 31, 1995. SETTING:Three te...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647838
更新日期:1998-06-01 00:00:00
abstract::We describe the prevalence of and risk factors for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-EB) in the long-term care facility (LTCF) setting. Colonization prevalence differed significantly across the 3 LTCFs evaluated in the study, with recent use of levofloxacin and fecal in...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/664055
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:We assessed the frequency and relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates to determine whether healthcare workers, the environment, or admitted patients could be a reservoir for MRSA on a burn trauma unit (BTU). We also assessed risk factors for MRSA colonization among BTU patie...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/668032
更新日期:2012-11-01 00:00:00
abstract::Intracavity ultrasound transducer handles are not routinely immersed in liquid high-level disinfectants. We show that residual bacteria, including pathogens, persist on more than 80% of handles that are not disinfected, whereas use of an automated device reduces contamination to background levels. Clinical staff shoul...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.12
更新日期:2015-05-01 00:00:00
abstract::We propose the use of a machine learning algorithm to improve possible COVID-19 case identification more quickly using a mobile phone-based web survey. This method could reduce the spread of the virus in susceptible populations under quarantine. ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.61
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To compare the impacts of different methicillin-resistant Staphylococcus aureus (MRSA) screening test options (eg, polymerase chain reaction [PCR], rapid culture) and program characteristics on the clinical outcomes and budget of a typical US hospital. METHODS:We developed an Excel-based decision-analytic mo...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/658332
更新日期:2011-03-01 00:00:00
abstract::We prospectively surveyed for rectal colonization with vancomycin-resistant Enterococcus among 93 high-risk pediatric patients who were hospitalized at least 5 (median, 20) days. Fifty-two patients (56%) had enterococcal colonization; none had active infection with Enterococcus. All enterococci were vancomycin-suscept...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647777
更新日期:1998-02-01 00:00:00
abstract::We reviewed the published data on the possible impact of medical injections and blood transfusions on the spread of human immunodeficiency virus (HIV) in Africa. We also compared these results to our experience in Rwanda, central Africa. The importance of medical injections in the epidemic of HIV infection seems to di...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645833
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVE:To determine the impact of the screening test, nursing workload, handwashing rates, and dependence of handwashing on risk level of patient visit on methicillin-resistant Staphylococcus aureus (MRSA) transmission among hospitalized patients. SETTING:General medical ward. METHODS:Monte Carlo simulation was us...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502589
更新日期:2005-07-01 00:00:00
abstract::The hospital-wide attack rate for Clostridium difficile-associated diarrhea at our tertiary-care university hospital was 0.02 per 100 patient discharges (0.02%) in 1982, but 0.41% and 1.47% in 1986 and 1987, respectively, with a peak incidence of 2.25% in the fourth quarter of 1987. Hospital antibiotic usage patterns ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646173
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:To describe factors associated with a rectal swab or stool sample positive for norovirus, rotavirus, or adenovirus. DESIGN:Retrospective study. SETTING:Charleston Area Medical Center, a regional academic medical center in Charleston, West Virginia. METHODS:Rectal swab or stool samples were obtained from pa...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/654004
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the antimicrobial efficacy of and risk of organisms developing resistance to 2 novel hand soaps: (1) a soap containing triclosan, polyhexamethylene biguanide, and benzethonium chloride added to a soap base (TPB soap); and (2) a soap containing farnesol, polyhexamethylene biguanide, and benzethoniu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/589723
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To document the costs and the benefits (both in terms of costs averted and of injuries averted) of education sessions and replacement of phlebotomy devices to ensure that needle recapping did not take place. DESIGN:The percentage of recapped needles and the rate of needlestick injuries were evaluated in 1990...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501681
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To develop and field test an implementation assessment tool for assessing progress of hospital units in implementing improvements for the prevention of ventilator-associated pneumonia (VAP) in a two-state collaborative, including data on actions implemented by participating teams and contextual factors that m...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/677832
更新日期:2014-10-01 00:00:00
abstract::Several discrete strategies have been suggested to prevent or reduce microbial resistance to antimicrobials, including optimal use of the agents (also known as good stewardship); control, removal, or restriction of antimicrobials; use of antimicrobials in combination; and rotational or cyclic use of antimicrobials. Th...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/503168
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:Laboratory-based characterization and traceback of Clostridium butyricum isolates linked to outbreak cases of neonatal necrotizing enterocolitis (NEC) in a hospital in China. METHODS:In total, 37 samples were collected during the NEC outbreak. Classical bacteriological methods were applied to isolate and ide...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.289
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To determine whether disinfection protocols currently used for gastroscopes are effective against cultures of Tropheryma whipplei. DESIGN:The bactericidal activity of 2% glutaraldehyde and two peracetic acids on the Twist-Marseille strain of T. whipplei grown in cell monolayers was determined. PATIENTS:Two ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502188
更新日期:2003-03-01 00:00:00