Abstract:
OBJECTIVE:Describe the clinical and molecular epidemiology of incident Clostridium difficile infection (CDI) cases in Chicago area acute healthcare facilities (HCFs). DESIGN AND SETTING:Laboratory, clinical, and epidemiologic information was collected for patients with incident CDI who were admitted to acute HCFs in February 2009. Stool cultures and restriction endonuclease analysis typing of the recovered C. difficile isolates was performed. PATIENTS:Two hundred sixty-three patients from 25 acute HCFs. RESULTS:Acute HCF rates ranged from 2 to 7 patients with CDI per 10,000 patient-days. The crude mortality rate was 8%, with 20 deaths occurring in patients with CDI. Forty-two (16%) patients had complications from CDI, including 4 patients who required partial, subtotal, or total colectomy, 3 of whom died. C. difficile was isolated and typed from 129 of 178 available stool specimens. The BI strain was identified in 79 (61%) isolates. Of patients discharged to long-term care who had their isolate typed, 36 (67%) had BI-associated CDI. CONCLUSIONS:Severe disease was common and crude mortality was substantial among patients with CDI in Chicago area acute HCFs in February 2009. The outbreak-associated BI strain was the predominant endemic strain identified, accounting for nearly two-thirds of cases. Focal HCF outbreaks were not reported, despite the presence of the BI strain. Transfer of patients between acute and long-term HCFs may have contributed to the high incidence of BI cases in this investigation.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Black SR,Weaver KN,Jones RC,Ritger KA,Petrella LA,Sambol SP,Vernon M,Burton S,Garcia-Houchins S,Weber SG,Lavin MA,Gerding D,Johnson S,Gerber SIdoi
10.1086/661283subject
Has Abstractpub_date
2011-09-01 00:00:00pages
897-902issue
9eissn
0899-823Xissn
1559-6834journal_volume
32pub_type
杂志文章abstract::Results from prospective surveillance of nosocomial infections (NIs) in a small community hospital were evaluated, and a case-control study was conducted. The rate of 1.4 NIs per 100 discharges determined by prospective surveillance was found to be underestimated. Prematurity, pediatric service, surgery, length of sta...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501920
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abstract::OBJECTIVE To elicit expert consensus on the likelihood of infectious outcomes (patient colonization or infection) following a broad range of infectious risk moments (IRMs) from observations in acute care. DESIGN Expert consensus study using modified Delphi technique. PARTICIPANTS Panel of 40 international experts incl...
journal_title:Infection control and hospital epidemiology
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doi:10.1017/ice.2017.327
更新日期:2018-03-01 00:00:00
abstract::Recent developments that are relevant to the ethics of infection control include the patient safety movement, the appearance of new diseases (notably, severe acute respiratory syndrome) that pose threats to healthcare workers, data confirming the suspicion that infection control measures such as isolation may compromi...
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1017/ice.2015.325
更新日期:2016-04-01 00:00:00
abstract::In a cross-sectional study of Thai medical students, we compared the seroprevalence of antibody to measles virus, rubella virus, varicella zoster virus, hepatitis A virus, and hepatitis B virus with self-reports of prior infection or vaccination. Self-report predicted immunity to varicella zoster virus only. These dat...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597508
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To determine the appropriateness of antibiotic prophylaxis regimens for major surgery in Korea. DESIGN:Retrospective study using a written survey for each patient who underwent arthroplasty, colon surgery, or hysterectomy. SETTING:Six tertiary hospitals in Seoul and Gyeonggi Province. PATIENTS:From each ho...
journal_title:Infection control and hospital epidemiology
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doi:10.1086/519180
更新日期:2007-08-01 00:00:00
abstract::Though many agents have been proposed as potential biological weapons, the feasibility of biological warfare is largely a matter of conjecture. The unpredictable and indiscriminate devastation caused by natural epidemics during wartime should warn us of the dangers of employing microbes as weapons. ...
journal_title:Infection control and hospital epidemiology
pub_type: 历史文章,杂志文章
doi:10.1086/646358
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVES:To compare the cost of hospitalization of patients with methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) versus patients with methicillin-sensitive S. aureus (MSSA) BSI, controlling for severity of underlying illness; and to identify risk factors associated with MRSA BSI. DESIG...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502417
更新日期:2004-05-01 00:00:00
abstract::Air conditioner condensates have not been previously associated with cases of Legionnaires' disease. We report the possible transmission of Legionella pneumophila serogroup 1 from a malfunctioning automobile air conditioning system's leaking water onto the floorboard of a car driven for a long distance by the patient....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502025
更新日期:2002-03-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605721
更新日期:2009-10-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/671268
更新日期:2013-08-01 00:00:00
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journal_title:Infection control and hospital epidemiology
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doi:10.1086/502144
更新日期:2003-11-01 00:00:00
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doi:10.1017/ice.2020.1291
更新日期:2020-10-26 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/591456
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:Investigation of a program to eradicate amebiasis using consecutive intensive mass screenings followed by medication in a large institute for adults with mental retardation in Taiwan. DESIGN:Prospective cohort study, with 3 years of follow-up. SETTING:A large, 450-bed institution for adults with mental reta...
journal_title:Infection control and hospital epidemiology
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doi:10.1086/518351
更新日期:2007-06-01 00:00:00
abstract::This study was designed to test the efficacy of a washer-disinfector in eliminating selected healthcare-associated pathogens from surgical instruments. Our results showed that a washer-disinfector was extremely effective in eliminating microorganisms (>7-log(10) reduction), including vegetative and spore-forming bacte...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/ice.2021.8
更新日期:2021-01-25 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/593952
更新日期:2009-02-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646732
更新日期:1993-05-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
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journal_title:Infection control and hospital epidemiology
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647625
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
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更新日期:2006-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1086/646627
更新日期:1993-01-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501744
更新日期:2000-03-01 00:00:00
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journal_title:Infection control and hospital epidemiology
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更新日期:2010-10-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647126
更新日期:1995-06-01 00:00:00