Abstract:
:OBJECTIVE To evaluate the efficacy of copper-coating in reducing environmental colonization in an intensive-care unit (ICU) with multidrug-resistant-organism (MDRO) endemicity DESIGN Interventional, comparative crossover trial SETTING The general ICU of Attikon University hospital in Athens, Greece PATIENTS Those admitted to ICU compartments A and B during the study period METHODS Before any intervention (phase 1), the optimum sampling method using 2 nylon swabs was validated. In phase 2, 6 copper-coated beds (ie, with coated upper, lower, and side rails) and accessories (ie, coated side table, intravenous [i.v.] pole stands, side-cart handles, and manual antiseptic dispenser cover) were introduced as follows: During phase 2a (September 2011 to February 2012), coated items were placed next to noncoated ones (controls) in both compartments A and B; during phase 2b (May 2012 to January 2013), all copper-coated items were placed in compartment A, and all noncoated ones (controls) in compartment B. Patients were randomly assigned to available beds. Environmental samples were cultured quantitatively for clinically important bacteria. Clinical and demographic data were collected from medical records. RESULTS Copper coating significantly reduced the percentage of colonized surfaces (55.6% vs 72.5%; P<.0001), the percentage of surfaces colonized by MDR gram-negative bacteria (13.8% vs 22.7%; P=.003) or by enterococci (4% vs 17%; P=.014), the total bioburden (2,858 vs 7,631 cfu/100 cm2; P=.008), and the bioburden of gram-negative isolates, specifically (261 vs 1,266 cfu/100 cm2; P=.049). This effect was more pronounced when the ratio of coated surfaces around the patient was increased (phase 2b). CONCLUSIONS Copper-coated items in an ICU setting with endemic high antimicrobial resistance reduced environmental colonization by MDROs. Infect Control Hosp Epidemiol 2017;38:765-771.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Souli M,Antoniadou A,Katsarolis I,Mavrou I,Paramythiotou E,Papadomichelakis E,Drogari-Apiranthitou M,Panagea T,Giamarellou H,Petrikkos G,Armaganidis Adoi
10.1017/ice.2017.52subject
Has Abstractpub_date
2017-07-01 00:00:00pages
765-771issue
7eissn
0899-823Xissn
1559-6834pii
S0899823X17000526journal_volume
38pub_type
杂志文章abstract::Infection control in the long-term-care facility has expanded substantially since "Topics in Long-Term Care" debuted in this journal in 1989. This section has been on hiatus, but now, after a 4-year lag, resumes its exploration of these topics. In the first article, endemic and epidemic infections in long-term care ar...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647831
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To describe the frequency of selected antimicrobial resistance patterns among pathogens causing device-associated and procedure-associated healthcare-associated infections (HAIs) reported by hospitals in the National Healthcare Safety Network (NHSN). METHODS:Data are included on HAIs (ie, central line-associ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/591861
更新日期:2008-11-01 00:00:00
abstract::Though many agents have been proposed as potential biological weapons, the feasibility of biological warfare is largely a matter of conjecture. The unpredictable and indiscriminate devastation caused by natural epidemics during wartime should warn us of the dangers of employing microbes as weapons. ...
journal_title:Infection control and hospital epidemiology
pub_type: 历史文章,杂志文章
doi:10.1086/646358
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVE:To describe the use of laminar airflow, body exhaust, and ultraviolet lights during total knee replacement (TKR) in four U.S. states. DESIGN:Survey of healthcare facilities. SETTING:Hospitals in Illinois, North Carolina, Ohio, and Tennessee that performed TKR during 2000 as identified by Medicare claims dat...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/505452
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVE:To characterize occupationally acquired human immunodeficiency virus (HIV) infection detected through case surveillance efforts in the United States. DESIGN:National surveillance systems, based on voluntary case reporting. SETTING:Healthcare or laboratory (clinical or research) settings. PATIENTS:Healthcar...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502178
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Clostridium difficile infection (CDI) is a reportable hospital metric associated with significant healthcare expenditures. The epidemiology of CDI is pivotal to the implementation of preventative measures. OBJECTIVE:To portray temporal CDI trends in Veterans Health Administration (VA) hospitals. DESIGN:A r...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.281
更新日期:2020-01-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) has been notifiable in Western Australia since 1985. This article reviews the notification data from 1994 to 1997, focusing on increases in MRSA notifications and the proportion that are local strains; changes in the geographical distribution of MRSA; and changes in a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501594
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To develop an automated method for ventilator-associated condition (VAC) surveillance and to compare its accuracy and efficiency with manual VAC surveillance SETTING:The intensive care units (ICUs) of 4 hospitals METHODS:This study was conducted at Detroit Medical Center, a tertiary care center in metropoli...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.127
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:Evaluate changes in antimicrobial use during COVID-19 and after implementation of a multispecialty COVID-19 clinical guidance team compared to pre-COVID-19 antimicrobial use. DESIGN:Retrospective observational study. SETTING:Tertiary-care academic medical center. PARTICIPANTS:Internal medicine and medical ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1291
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Fluoroquinolones have not been frequently implicated as a cause of Clostridium difficile outbreaks. Nosocomial C. difficile infections increased from 2.7 to 6.8 cases per 1000 discharges (P < .001). During the first 2 years of the outbreak, there were 253 nosocomial C. difficile infections; of ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502539
更新日期:2005-03-01 00:00:00
abstract::We aimed to determine the association between the presence of Acinetobacter baumannii in patient rooms and the carrier status of the occupants. Fifty-six (39%) of 143 rooms with A. baumannii-positive patients had results positive for A. baumannii. Only 49 (10%) of 485 rooms with A. baumannii-negative patients were pos...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/670209
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of detergent and friction on removal of traditional biofilm and cyclic-buildup biofilm (CBB) from polytetrafluoroethylene (PTFE) channels and to evaluate the efficacy of glutaraldehyde to kill residual bacteria after cleaning. METHODS:PTFE channels were exposed to artificial test soi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.306
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Peripheral venous catheters (PVCs) can be associated with serious infectious complications. We evaluated the effect of education and feedback on process measures to improve PVC care and infectious complications. DESIGN:Quasi-experimental controlled crossover study with sampling before and aft...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1086/665322
更新日期:2012-05-01 00:00:00
abstract::We characterized 57 isolates from a 2-phase clonal outbreak of New Delhi metallo-β-lactamase-producing Eschericha coli, involving 9 Israeli hospitals; all but 1 isolate belonged to sequence-type (ST) 410. Most isolates in the second phase harbored blaKPC-2 in addition to blaNDM-5. Genetic sequencing revealed most dual...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1361
更新日期:2020-12-29 00:00:00
abstract::An outbreak of vancomycin-resistant enterococci (VRE) began at the University of Massachusetts Medical Center in May 1993. As of September 1995, we had a total of 253 patients infected or colonized with VRE, with consequent increasing demand for private rooms. We analyzed results of surveillance cultures for VRE of 49...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The study was designed to compare the efficacies of bland soap handwash and isopropyl alcohol hand rinse in preventing transfer of aerobic gram-negative bacilli to urinary catheters via transient hand colonization acquired from direct patient contact. Glove juice recovery of gram-negative bacteria was conside...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646261
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:Standard precautions are advocated for reducing the number of injuries caused by needles and sharp medical devices ("sharps injuries"), but the effectiveness of gloves in preventing such injuries has not been established. We evaluated factors associated with gloving practices and identified associations betwe...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/655839
更新日期:2010-09-01 00:00:00
abstract::Antibiotic prescribing practices across the Veterans' Health Administration (VA) experienced significant shifts during the coronavirus disease 2019 (COVID-19) pandemic. From 2015 to 2019, antibiotic use between January and May decreased from 638 to 602 days of therapy (DOT) per 1,000 days present (DP), while the corre...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1277
更新日期:2020-10-20 00:00:00
abstract:OBJECTIVE:To investigate trends in plasmid types of methicillin-resistant Staphylococcus aureus over a 3-year period and determine the clinical impact of plasmid typing. DESIGN:Restriction endonuclease analysis of plasmid DNA (REAP) was used to type 270 clinical isolates. SETTING:A Veterans Affairs Medical Center. R...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646627
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Flash sterilization is most commonly used for emergency sterilization of unwrapped items in a gravity displacement sterilizer for three minutes. Sterilization quality assurance is monitored by biological indicators that require a 24-hour incubation prior to reading. In this study, we compared a new biological...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646767
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:To determine the number of Staphylococcus aureus isolates collected in a dental clinical environment and to determine their susceptibility to antimicrobial agents commonly used in dentistry. SETTING:Undergraduate clinic of the Dental School of Piracicaba, University of Campinas, Brazil. METHODS:Sterile cott...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/510867
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Existing knowledge of emergency department (ED) catheter-associated urinary tract infection (CAUTI) prevention is limited. We aimed to describe the motivations, perceived risks for CAUTI acquisition, and strategies used to address CAUTI risk among EDs that had existing CAUTI prevention programs. METHODS:In ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.267
更新日期:2016-02-01 00:00:00
abstract::Food is an established source of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Hand hygiene and cooking prevent transmission, but hands could be recontaminated by touching used cutting boards. ESBL-producing Escherichia coli were identified on 12% of cutting boards and 50% of gloves after poultry ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/675831
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:Two pilot studies were conducted to produce efficacy data on an observational tool designed to assess the use of Universal Precautions (UP) in patient care settings. The instrument addresses barrier precautions, hand-washing, handling of sharps, and avoidance of unprotected mouth to mouth resuscitation. DES...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646248
更新日期:1991-10-01 00:00:00
abstract::We assessed handrub consumption as a surrogate marker for hand hygiene compliance from 2007 to 2014. Handrub consumption varied substantially between departments but correlated in a mixed effects regression model with the number of patient-days and the observed hand hygiene compliance. Handrub consumption may suppleme...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.47
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To identify delayed prophylaxis from a pre-existing database and strategies to improve performance. SETTING:A skilled nursing facility with 14 floors (4 buildings). The "outbreak unit" was a 50- to 60-bed floor. METHODS:We performed surveillance during six seasons using one protocol. Prophylaxis was started...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501978
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To determine trends in compliance with the guidelines for preventing the transmission of Mycobacterium tuberculosis in healthcare facilities among New Jersey hospitals from 1989 through 1996. DESIGN:A voluntary questionnaire was sent to all 96 New Jersey hospitals in 1992. The 53 that responded were resurvey...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501627
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the cost-effectiveness of a dual strategy of tuberculin skin test (TST) and QuantiFERON-TB Gold (QFT-G) for screening of latent tuberculosis infection (LTBI) in healthcare workers (HCWs) and, as a secondary objective, to study relationships between TST results, QFT-G results, and sociodemographic ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/668436
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To determine the appropriateness of antibiotic prophylaxis regimens for major surgery in Korea. DESIGN:Retrospective study using a written survey for each patient who underwent arthroplasty, colon surgery, or hysterectomy. SETTING:Six tertiary hospitals in Seoul and Gyeonggi Province. PATIENTS:From each ho...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/519180
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To evaluate clonal dissemination of methicillin-resistant coagulase-negative staphylococci (CNS). SETTING:Neonatal intensive care unit of a 180-bed, university-affiliated general hospital. PATIENTS:Neonates admitted to the neonatal intensive care unit between March 1999 and October 2000, from whom CNS were ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502083
更新日期:2002-08-01 00:00:00