Evaluation of uncomplicated acute respiratory tract infection management in veterans: A national utilization review.

Abstract:

BACKGROUND:Antibiotics are overprescribed for acute respiratory tract infections (ARIs). Guidelines provide criteria to determine which patients should receive antibiotics. We assessed congruence between documentation of ARI diagnostic and treatment practices with guideline recommendations, treatment appropriateness, and outcomes. METHODS:A multicenter quality improvement evaluation was conducted in 28 Veterans Affairs facilities. We included visits for pharyngitis, rhinosinusitis, bronchitis, and upper respiratory tract infections (URI-NOS) that occurred during the 2015-2016 winter season. A manual record review identified complicated cases, which were excluded. Data were extracted for visits meeting criteria, followed by analysis of practice patterns, guideline congruence, and outcomes. RESULTS:Of 5,740 visits, 4,305 met our inclusion criteria: pharyngitis (n = 558), rhinosinusitis (n = 715), bronchitis (n = 1,155), URI-NOS (n = 1,475), or mixed diagnoses (>1 ARI diagnosis) (n = 402). Antibiotics were prescribed in 68% of visits: pharyngitis (69%), rhinosinusitis (89%), bronchitis (86%), URI-NOS (37%), and mixed diagnosis (86%). Streptococcal diagnostic testing was performed in 33% of pharyngitis visits; group A Streptococcus was identified in 3% of visits. Streptococcal tests were ordered less frequently for patients who received antibiotics (28%) than those who did not receive antibiotics 44%; P < .01). Although 68% of visits for rhinosinusitis had documentation of symptoms, only 32% met diagnostic criteria for antibiotics. Overall, 39% of patients with uncomplicated ARIs received appropriate antibiotic management. The proportion of 30-day return visits for ARI care was similar for appropriate (11%) or inappropriate (10%) antibiotic management (P = .22). CONCLUSIONS:Antibiotics were prescribed in most uncomplicated ARI visits, indicating substantial overuse. Practice was frequently discordant with guideline diagnostic and treatment recommendations.

authors

Bohan JG,Madaras-Kelly K,Pontefract B,Jones M,Neuhauser MM,Bidwell Goetz M,Burk M,Cunningham F,ARI Management Improvement Group.

doi

10.1017/ice.2019.16

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

438-446

issue

4

eissn

0899-823X

issn

1559-6834

pii

S0899823X19000163

journal_volume

40

pub_type

杂志文章
  • Nosocomial Neisseria meningitidis: molecular analysis of a clinical problem.

    abstract::Over a 1-week period, Neisseria meningitidis serogroup B was recovered from two patients in the intensive-care unit (ICU). A cross-infection was presumed when one patient developed invasive meningococcal disease and another patient was found to be colonized. Investigation by molecular typing showed that these cases we...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647589

    authors: Louie M,Simor AE,Rachlis A,Louie L

    更新日期:1997-03-01 00:00:00

  • Yersinia enterocolitica infections in hospitalized patients: the problem of hospital-acquired infections.

    abstract:OBJECTIVE:To study the epidemiology of Yersinia enterocolitica infections in hospitalized patients and to determine the frequency of hospital-acquired infection and the modes of transmission within the hospital. DESIGN:Descriptive study in which the clinical microbiology laboratory reported all positive Yersinia cultu...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646496

    authors: Cannon CG,Linnemann CC Jr

    更新日期:1992-03-01 00:00:00

  • The epidemiology of methicillin-resistant Staphylococcus aureus on a burn trauma unit.

    abstract:OBJECTIVE:We assessed the frequency and relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates to determine whether healthcare workers, the environment, or admitted patients could be a reservoir for MRSA on a burn trauma unit (BTU). We also assessed risk factors for MRSA colonization among BTU patie...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/668032

    authors: Schweizer M,Ward M,Cobb S,McDanel J,Leder L,Wibbenmeyer L,Latenser B,Diekema D,Herwaldt L

    更新日期:2012-11-01 00:00:00

  • Risk of infection due to central venous catheters: effect of site of placement and catheter type.

    abstract:OBJECTIVE:To determine the influence of catheter site and type (single- vs triple-lumen) on infection rates associated with central venous catheterization. DESIGN:Prospective observational study of all nontunneled central venous catheters over a 28-month period. Data collected included patient characteristics, inserti...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647742

    authors: Goetz AM,Wagener MM,Miller JM,Muder RR

    更新日期:1998-11-01 00:00:00

  • Nosocomial infections in HIV-infected patients: preliminary results from a multicenter surveillance system (1989-1995).

    abstract:OBJECTIVE:To describe the characteristics of and trends in nosocomial infection among human immunodeficiency virus (HIV)-infected patients. DESIGN:Multicenter prospective cohort study. SETTING/PATIENTS:HIV-infected patients were enrolled at time of first inpatient admission at five Veterans' Administration Medical Ce...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1086/647652

    authors: Stroud L,Srivastava P,Culver D,Bisno A,Rimland D,Simberkoff M,Elder H,Fierer J,Martone W,Gaynes R

    更新日期:1997-07-01 00:00:00

  • 3-Methyl-4-chlorophenol for prion decontamination of medical devices.

    abstract::Disinfectants containing 3-methyl-4-chlorophenol were tested for their capacity to inactivate the infectious agent of scrapie. Coincubation of brain homogenates prepared from terminally ill scrapie-infected hamsters with the disinfectants rendered the prion protein PrP(Sc) sensitive to proteinase K digestion. Inoculat...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/504450

    authors: Riemer C,Bamme T,Mok SW,Baier M

    更新日期:2006-07-01 00:00:00

  • Frequency of Hand Decontamination of Intraoperative Providers and Reduction of Postoperative Healthcare-Associated Infections: A Randomized Clinical Trial of a Novel Hand Hygiene System.

    abstract::BACKGROUND Healthcare provider hands are an important source of intraoperative bacterial transmission events associated with postoperative infection development. OBJECTIVE To explore the efficacy of a novel hand hygiene improvement system leveraging provider proximity and individual and group performance feedback in r...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/ice.2016.106

    authors: Koff MD,Brown JR,Marshall EJ,O'Malley AJ,Jensen JT,Heard SO,Longtine K,O'Neill M,Longtine J,Houston D,Robison C,Moulton E,Patel HM,Loftus RW

    更新日期:2016-08-01 00:00:00

  • Comparative Antimicrobial Efficacy of Two Hand Sanitizers in Intensive Care Units Common Areas: A Randomized, Controlled Trial.

    abstract::OBJECTIVE Contaminated hands of healthcare workers (HCWs) are an important source of transmission of healthcare-associated infections. Alcohol-based hand sanitizers, while effective, do not provide sustained antimicrobial activity. The objective of this study was to compare the immediate and persistent activity of 2 h...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/ice.2017.293

    authors: Deshpande A,Fox J,Wong KK,Cadnum JL,Sankar T,Jencson A,Schramm S,Fraser TG,Donskey CJ,Gordon S

    更新日期:2018-03-01 00:00:00

  • Emergency Department Catheter-Associated Urinary Tract Infection Prevention: Multisite Qualitative Study of Perceived Risks and Implemented Strategies.

    abstract:BACKGROUND:Existing knowledge of emergency department (ED) catheter-associated urinary tract infection (CAUTI) prevention is limited. We aimed to describe the motivations, perceived risks for CAUTI acquisition, and strategies used to address CAUTI risk among EDs that had existing CAUTI prevention programs. METHODS:In ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.267

    authors: Carter EJ,Pallin DJ,Mandel L,Sinnette C,Schuur JD

    更新日期:2016-02-01 00:00:00

  • Device-associated nosocomial infection rates in Turkish medical-surgical intensive care units.

    abstract:OBJECTIVE:To describe the incidence of device-associated nosocomial infections in medical-surgical intensive care units (MS ICUs) in a university hospital in Turkey and compare it with National Nosocomial Infections Surveillance (NNIS) system rates. DESIGN:Prospective surveillance study during a period of 27 months. D...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/503344

    authors: Inan D,Saba R,Yalcin AN,Yilmaz M,Ongut G,Ramazanoglu A,Mamikoglu L

    更新日期:2006-04-01 00:00:00

  • Economic analysis of reprocessing single-use medical devices: a systematic literature review.

    abstract:BACKGROUND:Although an increasing number of medical devices are labeled "for single use only," cleaning and reuse of single-use medical devices continues, because of the economic incentive. We conducted a survey of the economic literature to obtain the current evidence available and to assess the costs and benefits of ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/529587

    authors: Jacobs P,Polisena J,Hailey D,Lafferty S

    更新日期:2008-04-01 00:00:00

  • Evaluation of a new monochloramine generation system for controlling Legionella in building hot water systems.

    abstract:OBJECTIVE:To evaluate the efficacy of a new monochloramine generation system for control of Legionella in a hospital hot water distribution system. SETTING:A 495-bed tertiary care hospital in Pittsburgh, Pennsylvania. The hospital has 12 floors covering approximately 78,000 m(2). METHODS:The hospital hot water system...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/678418

    authors: Duda S,Kandiah S,Stout JE,Baron JL,Yassin M,Fabrizio M,Ferrelli J,Hariri R,Wagener MM,Goepfert J,Bond J,Hannigan J,Rogers D

    更新日期:2014-11-01 00:00:00

  • Annual tuberculin skin testing of employees at a university hospital: a cost-benefit analysis.

    abstract::The usefulness of routine annual tuberculin skin testing (purified protein derivative [PPD]) of hospital employees has been questioned. Between 1984 and the end of 1987 the PPD conversion rates of hospital employees at a university and psychiatric hospital in North Florida were compared. The number of employees in bot...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/645922

    authors: Raad I,Cusick J,Sherertz RJ,Sabbagh M,Howell N

    更新日期:1989-10-01 00:00:00

  • Rate of latent tuberculosis infection detected by occupational health screening of nurses new to a london teaching hospital.

    abstract::The prevalence of latent tuberculosis infection in a cohort of nurses new to a London hospital was 7.6% (13 of 171), using an interferon-gamma (IFN-gamma) release assay, and 16.2% (24 of 148), using the tuberculin skin test. On multivariate analysis, birth in a country with tuberculosis prevalence of more than 40 case...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/597546

    authors: Khanna P,Nikolayevskyy V,Warburton F,Dobson E,Drobniewski F

    更新日期:2009-06-01 00:00:00

  • The Development of Statistical Models for Predicting Surgical Site Infections in Japan: Toward a Statistical Model-Based Standardized Infection Ratio.

    abstract:OBJECTIVE:To develop and internally validate a surgical site infection (SSI) prediction model for Japan. DESIGN:Retrospective observational cohort study. METHODS:We analyzed surveillance data submitted to the Japan Nosocomial Infections Surveillance system for patients who had undergone target surgical procedures fro...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1017/ice.2015.302

    authors: Fukuda H,Kuroki M

    更新日期:2016-03-01 00:00:00

  • Positive deviance: a new strategy for improving hand hygiene compliance.

    abstract:OBJECTIVE:To evaluate the effectiveness of a positive deviance strategy for the improvement of hand hygiene compliance in 2 adult step-down units. DESIGN:A 9-month, controlled trial comparing the effect of positive deviance on compliance with hand hygiene. SETTING:Two 20-bed step-down units at a tertiary care private...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/649224

    authors: Marra AR,Guastelli LR,de Araújo CM,dos Santos JL,Lamblet LC,Silva M Jr,de Lima G,Cal RG,Paes AT,Cendoroglo Neto M,Barbosa L,Edmond MB,dos Santos OF

    更新日期:2010-01-01 00:00:00

  • Nosocomial dermatitis caused by Dermanyssus gallinae.

    abstract::The mite Dermanyssus gallinae may cause pruritic dermatitis in humans. We describe a case of nosocomial infestation with D. gallinae from an abandoned pigeon nest suspended on the front wall of the Hôpital Henri Mondor near a window. Close surveillance and regular destruction of pigeon nests could prevent these incide...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/528815

    authors: Bellanger AP,Bories C,Foulet F,Bretagne S,Botterel F

    更新日期:2008-03-01 00:00:00

  • Antimicrobial resistance in long-term-care facilities.

    abstract::During the last quarter century, numerous reports have indicated that antimicrobial resistance commonly is encountered in long-term-care facilities (LTCFs). Gram-negative uropathogens resistant to penicillin, cephalosporin, aminoglycoside, or fluoroquinolone antibiotics and methicillin-resistant Staphylococcus aureus ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/647257

    authors: Strausbaugh LJ,Crossley KB,Nurse BA,Thrupp LD

    更新日期:1996-02-01 00:00:00

  • Hepatitis C virus transmission from a healthcare worker to a patient.

    abstract::We investigated the source of infection in a patient who developed acute hepatitis C virus infection after cardiothoracic surgery. A healthcare worker was found to be infected with hepatitis C virus, and molecular analysis indicated the strain was similar to that found in the patient. The exact mode of transmission wa...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/510807

    authors: Lot F,Delarocque-Astagneau E,Thiers V,Bernet C,Rimlinger F,Desenclos JC,Chaud P,Dumay F

    更新日期:2007-02-01 00:00:00

  • Nosocomial infections in a community hospital in Mexico.

    abstract::Results from prospective surveillance of nosocomial infections (NIs) in a small community hospital were evaluated, and a case-control study was conducted. The rate of 1.4 NIs per 100 discharges determined by prospective surveillance was found to be underestimated. Prematurity, pediatric service, surgery, length of sta...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/501920

    authors: de Lourdes García-García M,Jiménez-Corona A,Jiménez-Corona ME,Solís-Bazaldúa M,Villamizar-Arciniegas CO,Valdespino-Gómez JL

    更新日期:2001-06-01 00:00:00

  • Usefulness of Adenosinetriphosphate Bioluminescence Assay (ATPmetry) for Monitoring the Reprocessing of Endoscopes.

    abstract:OBJECTIVE:To assess the diagnostic value of an adenosinetriphosphate bioluminescence assay (ATPmetry) to monitor the effectiveness of the reprocessing of endoscopes compared with microbiologic sampling. DESIGN:Diagnostic study. SETTING:A 2,200-bed teaching hospital performing 5,000 to 6,000 endoscopic procedures annu...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.212

    authors: Batailler P,Saviuc P,Picot-Gueraud R,Bosson JL,Mallaret MR

    更新日期:2015-12-01 00:00:00

  • Absence of association between use of ertapenem and change in antipseudomonal carbapenem susceptibility rates in 25 hospitals.

    abstract:OBJECTIVE:Ertapenem exposure has been reported to select for cross-resistance to other carbapenems in Pseudomonas aeruginosa in vitro. Single-center investigations report conflicting results. We evaluated ertapenem use and antipseudomonal carbapenem susceptibility for 6 years spanning the time of ertapenem adoption at ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1086/652154

    authors: Eagye KJ,Nicolau DP

    更新日期:2010-05-01 00:00:00

  • A shared vision of healthcare quality improvement.

    abstract::SHEA and the American Society for Quality's Health Care Division have been collaborating in areas of common concern to improve healthcare quality. We each possess a heritage of different but complementary approaches and stand a better chance of success together than apart. This presentation describes rapid growth of o...

    journal_title:Infection control and hospital epidemiology

    pub_type:

    doi:10.1086/501957

    authors: Birnbaum D,Health Care Quality Special Interest Group.

    更新日期:2001-09-01 00:00:00

  • Prevalence and risk factors associated with vancomycin-resistant Staphylococcus aureus precursor organism colonization among patients with chronic lower-extremity wounds in Southeastern Michigan.

    abstract:BACKGROUND:Of the 13 US vancomycin-resistant Staphylococcus aureus (VRSA) cases, 8 were identified in southeastern Michigan, primarily in patients with chronic lower-extremity wounds. VRSA infections develop when the vanA gene from vancomycin-resistant enterococcus (VRE) transfers to S. aureus. Inc18-like plasmids in V...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/671735

    authors: Tosh PK,Agolory S,Strong BL,Verlee K,Finks J,Hayakawa K,Chopra T,Kaye KS,Gilpin N,Carpenter CF,Haque NZ,Lamarato LE,Zervos MJ,Albrecht VS,McAllister SK,Limbago B,Maccannell DR,McDougal LK,Kallen AJ,Guh AY

    更新日期:2013-09-01 00:00:00

  • Improvement of intraoperative antibiotic prophylaxis in prolonged cardiac surgery by automated alerts in the operating room.

    abstract:OBJECTIVE:To assess the impact of an automated intraoperative alert to redose prophylactic antibiotics in prolonged cardiac operations. DESIGN:Randomized, controlled, evaluator-blinded trial. SETTING:University-affiliated hospital. PATIENTS:Patients undergoing cardiac surgery that lasted more than 4 hours after the ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1086/502109

    authors: Zanetti G,Flanagan HL Jr,Cohn LH,Giardina R,Platt R

    更新日期:2003-01-01 00:00:00

  • Susceptibility of Candida auris and Candida albicans to 21 germicides used in healthcare facilities.

    abstract::Candida auris is an emerging fungal pathogen that is often resistant to major classes of antifungal drugs. It is considered a serious global health threat because it can cause severe infections with frequent mortality in more than a dozen countries. It can survive on healthcare environmental surfaces for at least 7 da...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2019.1

    authors: Rutala WA,Kanamori H,Gergen MF,Sickbert-Bennett EE,Weber DJ

    更新日期:2019-03-01 00:00:00

  • Epidemiological and genetic characterization of Clostridium butyricum cultured from neonatal cases of necrotizing enterocolitis in China.

    abstract:OBJECTIVE:Laboratory-based characterization and traceback of Clostridium butyricum isolates linked to outbreak cases of neonatal necrotizing enterocolitis (NEC) in a hospital in China. METHODS:In total, 37 samples were collected during the NEC outbreak. Classical bacteriological methods were applied to isolate and ide...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2019.289

    authors: Dong Y,Li Y,Zhang D,Nguyen S,Maheshwari N,Hu Y,Cao Y,Li F,Fanning S

    更新日期:2020-08-01 00:00:00

  • An outbreak of bacteremias associated with Mycobacterium mucogenicum in a hospital water supply.

    abstract:OBJECTIVE:To investigate and determine the cause of an outbreak of Mycobacterium mucogenicum bacteremias in bone marrow transplant (BMT) and oncology patients. DESIGN:Case-control study and culturing of hospital water sources. Isolates were typed using molecular methods. SETTING:University-affiliated, tertiary-care m...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502341

    authors: Kline S,Cameron S,Streifel A,Yakrus MA,Kairis F,Peacock K,Besser J,Cooksey RC

    更新日期:2004-12-01 00:00:00

  • Frequency of Klebsiella pneumoniae carbapenemase (KPC)-producing and non-KPC-producing Klebsiella species contamination of healthcare workers and the environment.

    abstract::We examined contamination of healthcare worker (HCW) gown and gloves after caring for patients with Klebsiella pneumoniae carbapenemase (KPC)-producing and non-KPC-producing Klebsiella as a proxy for horizontal transmission. The rate of contamination with Klebsiella species is similar to that of contamination with met...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/675598

    authors: Rock C,Thom KA,Masnick M,Johnson JK,Harris AD,Morgan DJ

    更新日期:2014-04-01 00:00:00

  • Comparing rubbing and scrubbing surgical hand antisepsis with propan-1-ol 60% in accordance with European regulation UNE-EN 12791:2016+A1:2018.

    abstract::A crossover trial was conducted to compare hand rub and hand scrub-brush methods for reducing bacterial loads when using propan-1-ol-60% according to European regulations. Both methods significantly reduced the bacterial load immediately after antisepsis, but only the hand rub method achieved significant bacterial loa...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.1388

    authors: Martin-Villa C,Becerro-de-Bengoa-Vallejo R,Alou L,González N,Losa-Iglesias M,Gómez-Lus ML,Sevillano D

    更新日期:2021-01-22 00:00:00