Abstract:
OBJECTIVE:To determine the influence of catheter site and type (single- vs triple-lumen) on infection rates associated with central venous catheterization. DESIGN:Prospective observational study of all nontunneled central venous catheters over a 28-month period. Data collected included patient characteristics, insertion site, catheter type, and receipt of parenteral nutrition. End points were clinical infection (bacteremia or site infection) and catheter contamination (clinical infection or colonization with >15 colonies on semiquantitative culture). SETTING:Medical-surgical wards of Veterans' Affairs hospital. RESULTS:Three hundred catheters were inserted into 204 patients. Seventy percent were inserted into upper-body sites, and 30% were inserted into the femoral vein. Forty-five percent were triple-lumen catheters. Bacteremia occurred in 2.7% of catheter insertions; insertion-site infections developed in 1.3%, and catheter colonization developed in 12%. Catheter contamination was associated with emergent insertion (odds ratio [OR], 6.2; 95% confidence interval [CI95], 1.1-36.7; P=.04) by logistic regression and with femoral location (hazard, 4.2; CI95, 2.0-8.8; P=.0001) and history of transplantation (hazard, 2.8; CI95, 1.1-6.7; P=.024) by Cox regression. Clinical infection was not associated with any of the risk factors evaluated, although there was a trend for association with femoral location by Cox regression (hazard, 4.7; CI95, 0.82-26; P=.08). We did not identify an association between infection and use of triple-lumen catheters or parenteral nutrition. CONCLUSION:Our data support an association between intravenous catheter contamination and insertion at a femoral site.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Goetz AM,Wagener MM,Miller JM,Muder RRdoi
10.1086/647742subject
Has Abstractpub_date
1998-11-01 00:00:00pages
842-5issue
11eissn
0899-823Xissn
1559-6834pii
S019594170008677Xjournal_volume
19pub_type
杂志文章abstract::BACKGROUND In 2015, Denmark launched an automated surveillance system for hospital-acquired infections, the Hospital-Acquired Infections Database (HAIBA). OBJECTIVE To describe the algorithm used in HAIBA, to determine its concordance with point prevalence surveys (PPSs), and to present trends for hospital-acquired ba...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.1
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:The National Nosocomial Infections Surveillance (NNIS) System personnel report trends in antimicrobial-resistant pathogens. To validate select antimicrobial susceptibility testing results and to identify test methods that tend to produce errors, we conducted proficiency testing among NNIS System hospital labo...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502214
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To describe the epidemiology and the interventions used to control two methicillin-resistant Staphylococcus aureus (MRSA) epidemics involving 46 infants with two fatalities in a neonatal intensive care unit (NICU). SETTING:A 50-bed, level III NICU in a university hospital. INTERVENTIONS:After traditional in...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647285
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In August 2002, the Oklahoma State Department of Health received a report of six patients with unexplained hepatitis C virus (HCV) infection treated in the same pain remediation clinic. We investigated the outbreak's extent and etiology. DESIGN, SETTING, AND PARTICIPANTS:We conducted a retrosp...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502442
更新日期:2004-07-01 00:00:00
abstract::Standardizing healthcare surface sampling requires the evaluation of sampling tools for organism adherence. Here, 7 sampling tools were evaluated to assess their elution efficiencies in the presence of 5 pathogens. Foam sponges (80.6%), microfiber wipes (80.5%), foam swabs (77.9%), and cellulose sponges (66.5%) yielde...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.264
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To study the ability of a medical waste disposal process using chlorine dioxide to inactivate human immunodeficiency virus type 1 (HIV-1). DESIGN:Stock HIV-1 (HTLV-IIIB strain) was treated with chlorine dioxide under the following settings: cell culture medium alone, culture medium with 25% blood, culture me...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646798
更新日期:1993-09-01 00:00:00
abstract::The in vitro activities of bacitracin and mupirocin were compared for seven different strains of methicillin-resistant Staphylococcus aureus. Six of seven strains showed bacitracin minimum inhibitory concentrations (MICs) of 0.5 to 1.0 units/mL, and all seven had mupirocin MICs of 0.5 to 2 micrograms/mL. Time-kill stu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647270
更新日期:1996-03-01 00:00:00
abstract::During the last quarter century, numerous reports have indicated that antimicrobial resistance commonly is encountered in long-term-care facilities (LTCFs). Gram-negative uropathogens resistant to penicillin, cephalosporin, aminoglycoside, or fluoroquinolone antibiotics and methicillin-resistant Staphylococcus aureus ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/647257
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:We describe our experience using a real-time polymerase chain reaction (PCR) assay for methicillin-resistant Staphylococcus aureus (MRSA) during a period of active surveillance in the neonatal intensive care unit (NICU) from March 2007 until November 2007. OBJECTIVE:To compare PCR with bacterial culture met...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605321
更新日期:2009-09-01 00:00:00
abstract::Though many agents have been proposed as potential biological weapons, the feasibility of biological warfare is largely a matter of conjecture. The unpredictable and indiscriminate devastation caused by natural epidemics during wartime should warn us of the dangers of employing microbes as weapons. ...
journal_title:Infection control and hospital epidemiology
pub_type: 历史文章,杂志文章
doi:10.1086/646358
更新日期:1991-06-01 00:00:00
abstract::OBJECTIVE Recerntly, the role of the healthcare network, defined as a set of hospitals linked by patient transfers, has been increasingly considered in the control of antimicrobial resistance. Here, we investigate the potential impact of nursing homes on the spread of antimicrobial-resistant pathogens across the healt...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.59
更新日期:2016-07-01 00:00:00
abstract::The impact of US-style infection control programs is global. There are many Asian countries that have translated US-style infection control programs into their own programs, but reports of those efforts are rarely published in English. This article describes the development of infection control in Taiwan and the devel...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647126
更新日期:1995-06-01 00:00:00
abstract::An episode of acute hepatitis in a patient with hemophilia during immunoadsorption therapy initially was misinterpreted as a reactivated hepatitis C virus (HCV) infection, but ultimately was shown to be an exogenous reinfection during cohort treatment with another HCV-positive patient. This incident illustrates that p...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502063
更新日期:2002-06-01 00:00:00
abstract::We observed bacterial or fungal coinfections in COVID-19 patients admitted between March 1 and April 18, 2020 (152 of 4,267, 3.6%). Among these patients, mortality was 57%; 74% were intubated; 51% with bacteremia had central venous catheters. Time to culture positivity was 6-7 days, and 79% had received prior antibiot...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.368
更新日期:2021-01-01 00:00:00
abstract::US hospitals are engaged in an infection control arms race. Hospitals, specialties, and professional groups are spurring one another on to adopt progressively more aggressive measures in response to COVID-19 that often exceed federal and international standards. Examples include universal masking of providers and pati...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.211
更新日期:2020-11-01 00:00:00
abstract::Methodologies for evaluating the efficacy of antimicrobial agents in the bacterial flora of the hand involve variations of the "glove juice" or "sterile bag" procedures. In this study we demonstrate that the subungual flora contribute significantly to the recovery of bacteria in these procedures. Culturing hands that ...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章
doi:10.1086/645920
更新日期:1989-10-01 00:00:00
abstract::An intensive care nurse with eczema was repeatedly treated for methicillin-resistant Staphylococcus aureus (MRSA) carriage. Because cultures remained positive for MRSA, her house was investigated. Thirty-four percent of environmental samples yielded MRSA. Her children and cat were free of MRSA. The house was decontami...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/507966
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence and incidence of methicillin-resistant Staphylococcus aureus (MRSA) colonization among residents and healthcare workers (HCWs) of a long-term-care facility (LTCF), to assess possible routes of nosocomial spread, and to determine genetic relatedness of the isolates. SETTING:A 351-...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502524
更新日期:2005-02-01 00:00:00
abstract::This study reports an investigation of outbreaks of methicillin-resistant Staphylococcus aureus (MRSA) infection and colonization involving 17 newborns in the neonatal unit of a teaching hospital. A neonatal specialist colonized with MRSA that eventually became mupirocin-resistant was implicated as a recurrent source ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/513616
更新日期:2007-05-01 00:00:00
abstract::We reviewed the published data on the possible impact of medical injections and blood transfusions on the spread of human immunodeficiency virus (HIV) in Africa. We also compared these results to our experience in Rwanda, central Africa. The importance of medical injections in the epidemic of HIV infection seems to di...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645833
更新日期:1988-05-01 00:00:00
abstract::During the 1984-1985 influenza season, outbreaks of influenza A (H3N2) occurred in three Connecticut nursing homes. Influenza vaccination rates were 67% (96 out of 144), 35% (30 out of 85) and 69% (332 out of 483), respectively. The relative risk of illness for vaccinated compared to unvaccinated residents was 1.8 (95...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646214
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVE:To describe an outbreak of imipenem-resistant Acinetobacter baumannii (IR-Ab) and the measures for its control, and to investigate risk factors for IR-Ab acquisition. DESIGN:An observational and a case-control study. SETTING:A surgical intensive care unit (ICU) in a university tertiary care hospital. METHO...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501822
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The anterior nares are the most sensitive single site for detecting methicillin-resistant Staphylococcus aureus (MRSA) colonization. Colonization patterns of USA300 MRSA colonization are unknown. OBJECTIVES:To assess whether residents of extended care facilities who are colonized with USA300 MRSA have diffe...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/596114
更新日期:2009-04-01 00:00:00
abstract::The relation between antibiotic control and resistance was assessed by review of selected journal articles from 1988 through 1994. Most studies of control or monitoring do not report susceptibility pattern as an outcome measure. Several aspects of bias and confounding prevent more than analysis of temporal association...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/646954
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVE:The incidence of extended-spectrum beta-lactamase (ESbetaL)-mediated resistance has increased markedly during the past decade. Risk factors for colonization with ESbetaL-producing Escherichia coli and Klebsiella species (ESbetaL-EK) remain unclear, as do methods to control their further emergence. DESIGN:Cas...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502045
更新日期:2002-05-01 00:00:00
abstract::We aimed to determine the association between the presence of Acinetobacter baumannii in patient rooms and the carrier status of the occupants. Fifty-six (39%) of 143 rooms with A. baumannii-positive patients had results positive for A. baumannii. Only 49 (10%) of 485 rooms with A. baumannii-negative patients were pos...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/670209
更新日期:2013-05-01 00:00:00
abstract::We report nosocomial infection with Vibrio cholerae 01, in four seriously ill individuals and one infant in Guatemala. Nosocomial cholera occurs in developing countries in Latin America and should be suspected in hospitalized patients with diarrhea, especially during community outbreaks, in order to institute appropri...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647321
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:To devise a system for surveying the frequency of nosocomial infections in a tertiary care hospital in a developing country. DESIGN:Prospective selective surveillance by nurses of the charts of patients at high risk for nosocomial infections, as identified by a form completed by resident physicians. The sens...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646715
更新日期:1993-04-01 00:00:00
abstract::Water samples taken from extracorporeal membrane oxygenator (ECMO) devices used at University Hospitals Birmingham yielded high total viable counts (TVCs) containing a variety of microorganisms, including M. chimaera. Disinfection resulted in the reduction of TVCs and eradication of Mycobacterium chimaera. Weekly disi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.163
更新日期:2017-10-01 00:00:00
abstract::More than 90% of Thai hospitals surveyed reported implementing environmental cleaning and disinfection (ECD) protocols. Hospital epidemiologist presence was associated with the existence of an ECD checklist (P=.01) and of ECD auditing (P=.001), while good and excellent hospital administrative support were associated w...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.171
更新日期:2017-10-01 00:00:00