Comparative killing kinetics of methicillin-resistant Staphylococcus aureus by bacitracin or mupirocin.

Abstract:

:The in vitro activities of bacitracin and mupirocin were compared for seven different strains of methicillin-resistant Staphylococcus aureus. Six of seven strains showed bacitracin minimum inhibitory concentrations (MICs) of 0.5 to 1.0 units/mL, and all seven had mupirocin MICs of 0.5 to 2 micrograms/mL. Time-kill studies revealed 2.6- to 4.5-log reduction in 24 hours with strains susceptible to bacitracin (4 units/mL) and 0 to 2.2 reduction with mupirocin (16 micrograms/mL). Bacitracin should be considered further for in vivo studies because of enhanced bacteriocidal effect and lower cost.

authors

Chapnick EK,Gradon JD,Kreiswirth B,Lutwick LI,Schaffer BC,Schiano TD,Levi MH

doi

10.1086/647270

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

178-80

issue

3

eissn

0899-823X

issn

1559-6834

journal_volume

17

pub_type

杂志文章
  • Efficient recovery of fluoroquinolone-susceptible and fluoroquinolone-resistant Escherichia coli strains from frozen samples.

    abstract::We assessed the rate of recovery of fluoroquinolone-resistant and fluoroquinolone-susceptible Escherichia coli isolates from culture of frozen perirectal swab samples compared with the results for culture of the same specimen before freezing. Recovery rates for these 2 classes of E. coli were 91% and 83%, respectively...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/529590

    authors: Lautenbach E,Santana E,Lee A,Tolomeo P,Black N,Babson A,Perencevich EN,Harris AD,Smith CA,Maslow J

    更新日期:2008-04-01 00:00:00

  • Optimizing utilization of beta-lactam surgical prophylaxis through implementation of a structured allergy assessment tool in a presurgical clinic.

    abstract::In patients with β-lactam allergies, administration of non-β-lactam surgical prophylaxis is associated with increased risk of infection. Although many patients self-report β-lactam allergies, most are unconfirmed or mislabeled. A quality improvement process, utilizing a structured β-lactam allergy tool, was implemente...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2019.274

    authors: Margallo JP,Smith EA,Marks G,Ben-Aderet M,Yang H,Madhusudhan M,Krishna S,Duran A,Friedman A,Cassel SL,Tran H,Shane R,Murthy RK,Grein JD

    更新日期:2019-12-01 00:00:00

  • Evaluating the Relationship Between Hospital Antibiotic Use and Antibiotic Resistance in Common Nosocomial Pathogens.

    abstract::OBJECTIVE The relationship between hospital antibiotic use and antibiotic resistance is poorly understood. We evaluated the association between antibiotic utilization and resistance in academic and community hospitals in Ontario, Canada. METHODS We conducted a multicenter observational ecological study of 37 hospitals...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1017/ice.2017.222

    authors: Wang A,Daneman N,Tan C,Brownstein JS,MacFadden DR

    更新日期:2017-12-01 00:00:00

  • An outbreak of Pseudomonas aeruginosa respiratory tract infections associated with intrinsically contaminated ultrasound transmission gel.

    abstract::We describe an outbreak of Pseudomonas aeruginosa respiratory tract infections related to intrinsically contaminated ultrasound gel used for intraoperative transesophageal echocardiograms in cardiovascular surgery patients. This investigation led to a product safety alert by the Food and Drug Administration and the de...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/671268

    authors: Chittick P,Russo V,Sims M,Robinson-Dunn B,Oleszkowicz S,Sawarynski K,Powell K,Makin J,Darnell E,Boura JA,Boyanton B,Band J

    更新日期:2013-08-01 00:00:00

  • Healthcare-Associated Transmission of Plasmodium falciparum in New York City.

    abstract::A patient with no risk factors for malaria was hospitalized in New York City with Plasmodium falciparum infection. After investigating all potential sources of infection, we concluded the patient had been exposed to malaria while hospitalized less than 3 weeks earlier. Molecular genotyping implicated patient-to-patien...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.236

    authors: Lee EH,Adams EH,Madison-Antenucci S,Lee L,Barnwell JW,Whitehouse J,Clement E,Bajwa W,Jones LE,Lutterloh E,Weiss D,Ackelsberg J

    更新日期:2016-01-01 00:00:00

  • Long-term outcomes of an antimicrobial stewardship program implemented in a hospital with low baseline antibiotic use.

    abstract:OBJECTIVE:To evaluate the long-term outcomes of an antimicrobial stewardship program (ASP) implemented in a hospital with low baseline antibiotic use. DESIGN:Quasi-experimental, interrupted time-series study. SETTING:Public safety net hospital with 525 beds. INTERVENTION:Implementation of a formal ASP in July 2008. ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.41

    authors: Jenkins TC,Knepper BC,Shihadeh K,Haas MK,Sabel AL,Steele AW,Wilson ML,Price CS,Burman WJ,Mehler PS

    更新日期:2015-06-01 00:00:00

  • Statistical quality control methods in infection control and hospital epidemiology, part I: Introduction and basic theory.

    abstract::This article is the first in a two-part series discussing and illustrating the application of statistical process control (SPC) to processes often examined by hospital epidemiologists. The basic philosophical and theoretical foundations of statistical quality control and their relation to epidemiology are emphasized i...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/647795

    authors: Benneyan JC

    更新日期:1998-03-01 00:00:00

  • Transmission of Staphylococcus aureus from dry surface biofilm (DSB) via different types of gloves.

    abstract:BACKGROUND:Pathogens can survive for extended periods when incorporated into biofilm on dry hospital surfaces (ie, dry-surface biofilm, DSB). Bacteria within biofilm are protected from desiccation and have increased tolerance to cleaning agents and disinfectants. OBJECTIVE:We hypothesized that gloved hands of healthca...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2018.285

    authors: Tahir S,Chowdhury D,Legge M,Hu H,Whiteley G,Glasbey T,Deva AK,Vickery K

    更新日期:2019-01-01 00:00:00

  • Strategies for the management of varicella-susceptible healthcare workers after a known exposure.

    abstract::Three different sequentially applied post-varicella zoster virus (VZV) exposure management strategies were employed over a 43-month period. We began by using a standard post-exposure protocol in which 50 susceptible healthcare workers (HCW) involved in hospital exposures were furloughed from work at a loss to the hosp...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646176

    authors: Josephson A,Karanfil L,Gombert ME

    更新日期:1990-06-01 00:00:00

  • Hand Rub Consumption Has Almost Doubled in 132 German Hospitals Over 9 Years.

    abstract::Annual surveillance data (2007-2015), collected continuously in 132 German hospitals, was evaluated for development of alcohol-based hand-rub consumption (AHC) as a surrogate parameter for hand hygiene adherence. Overall, the median increase in AHC was 94%. The increases over 9 years were significant in all units and ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2017.71

    authors: Wetzker W,Walter J,Bunte-Schönberger K,Schwab F,Behnke M,Gastmeier P,Reichardt C

    更新日期:2017-07-01 00:00:00

  • Studies of ventilation efficiency in a protective isolation room by the use of a scale model.

    abstract:OBJECTIVE:To assess the ability of a protective isolation room ventilation system to reduce patient exposure to airborne infectious agents, using a small-scale model that permits cost-effective and unobtrusive study of relevant indices of performance. DESIGN:A one-half scale model of a protective isolation room at the...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647181

    authors: Marshall JW,Vincent JH,Kuehn TH,Brosseau LM

    更新日期:1996-01-01 00:00:00

  • Hospital Water Management Programs for Legionella Prevention, Minnesota, 2017.

    abstract::Infection preventionists at Minnesota hospitals were surveyed to determine whether they had Legionella water management plans. Of 137 hospitals, 84 (61%) responded. Among them, 27% hospitals had a water management plan, 21% regularly sampled for Legionella, and 51% had knowledge of ASHRAE Legionella prevention standar...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2017.310

    authors: Danila RN,Koranteng N,Como-Sabetti KJ,Robinson TJ,Laine ES

    更新日期:2018-03-01 00:00:00

  • Statewide collaboration to evaluate the effects of blood loss and transfusion on surgical site infection after hysterectomy.

    abstract::We used mandatory public reporting as an impetus to perform a statewide study to define risk factors for surgical site infection. Among women who underwent abdominal hysterectomy, blood transfusion was a significant risk factor for surgical site infection in patients who experienced blood loss of less than 500 mL. ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/663341

    authors: Young H,Berumen C,Knepper B,Miller A,Silverman M,Gilmartin H,Wodrich E,Alexander S,Price CS

    更新日期:2012-01-01 00:00:00

  • Epidemiologic approaches to quality assessment.

    abstract::Hospital epidemiologists have an opportunity to apply their skills to hospital quality problems other than infection control. Soon, hospitals will be required to collect and report numerous quality indicators, whose results will require epidemiologic interpretation. For those who choose to make the transition into qua...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647065

    authors: Simmons BP,Kritchevsky SB

    更新日期:1995-02-01 00:00:00

  • Risk of infection due to central venous catheters: effect of site of placement and catheter type.

    abstract:OBJECTIVE:To determine the influence of catheter site and type (single- vs triple-lumen) on infection rates associated with central venous catheterization. DESIGN:Prospective observational study of all nontunneled central venous catheters over a 28-month period. Data collected included patient characteristics, inserti...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647742

    authors: Goetz AM,Wagener MM,Miller JM,Muder RR

    更新日期:1998-11-01 00:00:00

  • A shared vision of healthcare quality improvement.

    abstract::SHEA and the American Society for Quality's Health Care Division have been collaborating in areas of common concern to improve healthcare quality. We each possess a heritage of different but complementary approaches and stand a better chance of success together than apart. This presentation describes rapid growth of o...

    journal_title:Infection control and hospital epidemiology

    pub_type:

    doi:10.1086/501957

    authors: Birnbaum D,Health Care Quality Special Interest Group.

    更新日期:2001-09-01 00:00:00

  • Prevalence of colonization with community-associated methicillin-resistant Staphylococcus aureus among end-stage renal disease patients and healthcare workers.

    abstract:OBJECTIVE:To evaluate the prevalence, epidemiologic features, and molecular characteristics of colonization with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) among hospitalized dialysis patients and their healthcare workers (HCWs). DESIGN:Prospective observational clinical and laboratory ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/592983

    authors: Johnson LB,Jose J,Yousif F,Pawlak J,Saravolatz LD

    更新日期:2009-01-01 00:00:00

  • Methicillin‐resistant Staphylococcus aureus and the media.

    abstract::How the media communicate and how the scientific community influences the media are important factors to consider in the public health response to emerging pathogens, including methicillin-resistant Staphylococcus aureus. Social representation theory suggests that the media link "the threatening" to commonplace "ancho...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/656000

    authors: Perencevich EN,Treise DM

    更新日期:2010-11-01 00:00:00

  • Vertical transmission of Citrobacter diversus documented by DNA fingerprinting.

    abstract:OBJECTIVE:To confirm the vertical transmission of Citrobacter diversus from a mother to her infant and to evaluate the epidemiologic usefulness of a new automated procedure for analysis of polymerase chain reaction (PCR)-generated DNA fingerprints. DESIGN:Repetitive element-based PCR (rep-PCR) analysis of C diversus i...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647009

    authors: Harvey BS,Koeuth T,Versalovic J,Woods CR,Lupski JR

    更新日期:1995-10-01 00:00:00

  • High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies.

    abstract:BACKGROUND:Despite contact isolation precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA), MRSA infections are increasing in many countries. OBJECTIVE:To evaluate the role of a potential unrecognized reservoir of MRSA carried by patients in acute care wards, we determined the prevalence of ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502514

    authors: Lucet JC,Grenet K,Armand-Lefevre L,Harnal M,Bouvet E,Regnier B,Andremont A

    更新日期:2005-02-01 00:00:00

  • Limitations of forehead infrared body temperature detection for fever screening for severe acute respiratory syndrome.

    abstract::We investigated alternative measurement methodology for infrared body thermometry to increase accuracy for outdoor fever screening during the 2003 SARS epidemic. Our results indicate that the auditory meatus temperature is a superior alternative compared with the forehead body surface temperature due to its close appr...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章

    doi:10.1086/502351

    authors: Liu CC,Chang RE,Chang WC

    更新日期:2004-12-01 00:00:00

  • Prospective evaluation of colonization with extended-spectrum beta-lactamase (ESBL)-producing enterobacteriaceae among patients at hospital admission and of subsequent colonization with ESBL-producing enterobacteriaceae among patients during hospitalizati

    abstract:OBJECTIVE:To determine the rates of and risk factors for carriage and acquisition of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae during hospitalization. DESIGN:Cohort study. SETTING:Shaare Zedek Medical Center, a 550-bed teaching hospital. METHODS:During a 5-month period (February 1-June 30,...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/597505

    authors: Friedmann R,Raveh D,Zartzer E,Rudensky B,Broide E,Attias D,Yinnon AM

    更新日期:2009-06-01 00:00:00

  • Healthcare-associated influenza in Canadian hospitals from 2006 to 2012.

    abstract:OBJECTIVE:To determine trends, patient characteristics, and outcome of patients with healthcare-associated influenza in Canadian hospitals. DESIGN:Prospective surveillance of laboratory-confirmed influenza among hospitalized adults was conducted from 2006 to 2012. Adults with positive test results at or after admissio...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/674858

    authors: Taylor G,Mitchell R,McGeer A,Frenette C,Suh KN,Wong A,Katz K,Wilkinson K,Amihod B,Gravel D,Canadian Nosocomial Infection Surveillance Program.

    更新日期:2014-02-01 00:00:00

  • Postoperative burden of hospital-acquired Clostridium difficile infection.

    abstract::OBJECTIVE Clostridium difficile infection (CDI) is a common hospital-acquired infection. Previous reports on the incidence, risk factors, and impact of CDI on resources in the surgical population are limited. In this context, we study CDI across diverse surgical settings. METHODS We prospectively identified patients w...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2014.8

    authors: Abdelsattar ZM,Krapohl G,Alrahmani L,Banerjee M,Krell RW,Wong SL,Campbell DA,Aronoff DM,Hendren S

    更新日期:2015-01-01 00:00:00

  • Optimal frequency of changing intravenous administration sets: is it safe to prolong use beyond 72 hours?

    abstract:OBJECTIVE:To determine the safety and cost-effectiveness of replacing the intravenous (IV) tubing sets in hospitalized patients at 4- to 7-day intervals instead of every 72 hours. DESIGN:Prospective, randomized study of infusion-related contamination associated with changing IV tubing sets within 3 days versus within ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1086/501879

    authors: Raad I,Hanna HA,Awad A,Alrahwan A,Bivins C,Khan A,Richardson D,Umphrey JL,Whimbey E,Mansour G

    更新日期:2001-03-01 00:00:00

  • Potential nosocomial exposure to Mycobacterium tuberculosis from a bronchoscope.

    abstract:OBJECTIVE:To investigate a possible nosocomial outbreak of tuberculosis (TB). DESIGN:Retrospective cohort study. SETTING:Community hospital. METHODS:We reviewed medical records, hospital infection control measures, and potential locations of nosocomial exposure. We examined the results of acid-fast bacilli (AFB) sme...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502144

    authors: Larson JL,Lambert L,Stricof RL,Driscoll J,McGarry MA,Ridzon R

    更新日期:2003-11-01 00:00:00

  • Requirements for infrastructure and essential activities of infection control and epidemiology in out-of-hospital settings: a consensus panel report. Association for Professionals in Infection Control and Epidemiology and Society for Healthcare Epidemiolo

    abstract::In 1997 the Association for Professionals in Infection Control and Epidemiology and the Society for Healthcare Epidemiology of America established a consensus panel to develop recommendations for optimal infrastructure and essential activities of infection control and epidemiology programs in out-of-hospital settings....

    journal_title:Infection control and hospital epidemiology

    pub_type: 共识发展会议,指南,杂志文章,评审

    doi:10.1086/501569

    authors: Friedman C,Barnette M,Buck AS,Ham R,Harris JA,Hoffman P,Johnson D,Manian F,Nicolle L,Pearson ML,Perl TM,Solomon SL

    更新日期:1999-10-01 00:00:00

  • Ultraviolet powder versus ultraviolet gel for assessing environmental cleaning.

    abstract::We compared cleaning rates associated with use of a white ultraviolet (UV) powder versus a transparent UV gel among units with various degrees of previous experience with UV powder. The study outcome was the presence of discordant cleaning (removal of powder without the removal of gel, or vice versa). We found higher ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/663713

    authors: Munoz-Price LS,Fajardo-Aquino Y,Arheart KL

    更新日期:2012-02-01 00:00:00

  • Duration of virus shedding after trivalent intranasal live attenuated influenza vaccination in adults.

    abstract:OBJECTIVE:To characterize the probability and duration of viral shedding among adults given trivalent live attenuated influenza vaccine (LAIV). DESIGN:Prospective surveillance study. METHODS:Nasal wash samples were collected from adult volunteers at baseline and on days 3, 7, and 10 and between days 17 and 21 followi...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502574

    authors: Talbot TR,Crocker DD,Peters J,Doersam JK,Ikizler MR,Sannella E,Wright PE,Edwards KM

    更新日期:2005-05-01 00:00:00

  • Chasing the rate: An interrupted time series analysis of interventions targeting reported hospital onset Clostridioides difficile, 2013-2018.

    abstract:OBJECTIVE:To assess the impact of major interventions targeting infection control and diagnostic stewardship in efforts to decrease Clostridioides difficile hospital onset rates over a 6-year period. DESIGN:Interrupted time series. SETTING:The study was conducted in an 865-bed academic medical center. METHODS:Monthl...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.247

    authors: Doll ME,Zhao J,Kang L,Rittmann B,Alvarez M,Fleming M,Cooper K,Stevens MP,Bearman G

    更新日期:2020-10-01 00:00:00