Colonization sites of USA300 methicillin-resistant Staphylococcus aureus in residents of extended care facilities.

Abstract:

BACKGROUND:The anterior nares are the most sensitive single site for detecting methicillin-resistant Staphylococcus aureus (MRSA) colonization. Colonization patterns of USA300 MRSA colonization are unknown. OBJECTIVES:To assess whether residents of extended care facilities who are colonized with USA300 MRSA have different nares or skin colonization findings, compared with residents who are colonized with non-USA300 MRSA strains. METHODS:The study population included residents of 5 extended care units in 3 separate facilities who had a recent history of MRSA colonization. Specimens were obtained weekly for surveillance cultures from the anterior nares, perineum, axilla, and skin breakdown (if present) for 3 weeks. MRSA isolates were categorized as USA300 MRSA or non-USA300 MRSA. RESULTS:Of the 193 residents who tested positive for MRSA, 165 were colonized in the anterior nares, and 119 were colonized on their skin. Eighty-four percent of USA300 MRSA-colonized residents had anterior nares colonization, compared with 86% of residents colonized with non-USA300 MRSA (P= .80). Sixty-six percent of USA300 MRSA-colonized residents were colonized on the skin, compared with 59% of residents colonized with non-USA300 MRSA (P= .30). CONCLUSIONS:Colonization patterns of USA300 MRSA and non-USA300 MRSA are similar in residents of extended care facilities. Anterior nares cultures will detect most--but not all--people who are colonized with MRSA, regardless of whether it is USA300 or non-USA300 MRSA.

authors

Shurland SM,Stine OC,Venezia RA,Johnson JK,Zhan M,Furuno JP,Miller RR,Johnson T,Roghmann MC

doi

10.1086/596114

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

313-8

issue

4

eissn

0899-823X

issn

1559-6834

journal_volume

30

pub_type

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