Abstract:
BACKGROUND AND OBJECTIVE:In August 2002, the Oklahoma State Department of Health received a report of six patients with unexplained hepatitis C virus (HCV) infection treated in the same pain remediation clinic. We investigated the outbreak's extent and etiology. DESIGN, SETTING, AND PARTICIPANTS:We conducted a retrospective cohort study of clinic patients, including a serologic survey, interviews of infected patients, and reviews of medical records and staff infection control practices. Patients received outpatient pain remediation treatments one afternoon a week in a clinic within a hospital. Cases were defined as HCV or hepatitis B virus (HBV) infections among patients who reported no prior diagnosis or risk factors for disease or reported previous risk factors but had evidence of acute infection. RESULTS:Of 908 patients, 795 (87.6%) were tested, and 71 HCV-infected patients (8.9%) and 31 HBV-infected patients (3.9%) met the case definition. Multiple HCV genotypes were identified. Significantly higher HCV infection rates were found among individuals treated after an HCV-infected patient during the same visit (adjusted odds ratio [AOR], 6.2; 95% confidence interval [CI95], 2.4-15.8); a similar association was observed for HBV (AOR, 2.9; CI95, 1.3-6.5). Review of staff practices revealed the nurse anesthetist had been using the same syringe-needle to sequentially administer sedation medications to every treated patient each clinic day. CONCLUSIONS:Reuse of needles-syringes was the mechanism for patient-to-patient transmission of HCV and HBV in this large nosocomial outbreak. Further education and stricter oversight of infection control practices may prevent future outbreaks.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Comstock RD,Mallonee S,Fox JL,Moolenaar RL,Vogt TM,Perz JF,Bell BP,Crutcher JMdoi
10.1086/502442subject
Has Abstractpub_date
2004-07-01 00:00:00pages
576-83issue
7eissn
0899-823Xissn
1559-6834pii
ICHE8461journal_volume
25pub_type
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journal_title:Infection control and hospital epidemiology
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abstract:OBJECTIVE:Laboratory-based characterization and traceback of Clostridium butyricum isolates linked to outbreak cases of neonatal necrotizing enterocolitis (NEC) in a hospital in China. METHODS:In total, 37 samples were collected during the NEC outbreak. Classical bacteriological methods were applied to isolate and ide...
journal_title:Infection control and hospital epidemiology
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journal_title:Infection control and hospital epidemiology
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/589906
更新日期:2008-08-01 00:00:00
abstract::To ascertain the microbiology of skin abscesses, emergency department records were reviewed to identify patients with debrided skin abscesses. Methicillin-resistant Staphylococcus aureus was isolated from 255 (67.6%) of 377 culture samples from episodes in the adult cohort and from 145 (79.7%) of 182 culture samples f...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/516799
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abstract::Candida auris is an emerging fungal pathogen that is often resistant to major classes of antifungal drugs. It is considered a serious global health threat because it can cause severe infections with frequent mortality in more than a dozen countries. It can survive on healthcare environmental surfaces for at least 7 da...
journal_title:Infection control and hospital epidemiology
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abstract:OBJECTIVE:To describe the incidence of device-associated nosocomial infections in medical-surgical intensive care units (MS ICUs) in a university hospital in Turkey and compare it with National Nosocomial Infections Surveillance (NNIS) system rates. DESIGN:Prospective surveillance study during a period of 27 months. D...
journal_title:Infection control and hospital epidemiology
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journal_title:Infection control and hospital epidemiology
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更新日期:2016-01-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2013-06-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/669523
更新日期:2013-03-01 00:00:00
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journal_title:Infection control and hospital epidemiology
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更新日期:2020-12-01 00:00:00
abstract::Disinfectants containing 3-methyl-4-chlorophenol were tested for their capacity to inactivate the infectious agent of scrapie. Coincubation of brain homogenates prepared from terminally ill scrapie-infected hamsters with the disinfectants rendered the prion protein PrP(Sc) sensitive to proteinase K digestion. Inoculat...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/504450
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To determine trends in compliance with the guidelines for preventing the transmission of Mycobacterium tuberculosis in healthcare facilities among New Jersey hospitals from 1989 through 1996. DESIGN:A voluntary questionnaire was sent to all 96 New Jersey hospitals in 1992. The 53 that responded were resurvey...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501627
更新日期:1999-05-01 00:00:00
abstract::A surgeon-specific computer-generated monthly questionnaire was used to improve surveillance of surgical wound infections in outpatients as well as inpatients following discharge. From July 1988 through June 1989, 20,536 surgical procedures were performed at our medical center, of which 53% were for outpatients. The t...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646084
更新日期:1990-10-01 00:00:00
abstract::In a cross-sectional study of Thai medical students, we compared the seroprevalence of antibody to measles virus, rubella virus, varicella zoster virus, hepatitis A virus, and hepatitis B virus with self-reports of prior infection or vaccination. Self-report predicted immunity to varicella zoster virus only. These dat...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597508
更新日期:2009-06-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/659407
更新日期:2011-05-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502561
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:We describe our experience using a real-time polymerase chain reaction (PCR) assay for methicillin-resistant Staphylococcus aureus (MRSA) during a period of active surveillance in the neonatal intensive care unit (NICU) from March 2007 until November 2007. OBJECTIVE:To compare PCR with bacterial culture met...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605321
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To determine whether alcohol hand disinfection is an effective alternative to traditional agents for the pre-surgical scrub. DESIGN:A prospective clinical trial of a 70% isopropanol pre-surgical hand disinfectant. SETTING:The operating room suites at two hospital sites in British Columbia. METHODS:Cases we...
journal_title:Infection control and hospital epidemiology
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doi:10.1086/501835
更新日期:2001-10-01 00:00:00
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journal_title:Infection control and hospital epidemiology
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doi:10.1086/657909
更新日期:2011-02-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
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journal_title:Infection control and hospital epidemiology
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doi:10.1086/593952
更新日期:2009-02-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/519928
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To report the International Nosocomial Infection Control Consortium surveillance data from 40 hospitals (20 cities) in India 2004-2013. METHODS:Surveillance using US National Healthcare Safety Network's criteria and definitions, and International Nosocomial Infection Control Consortium methodology. RESULTS:...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.276
更新日期:2016-02-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/592983
更新日期:2009-01-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.191
更新日期:2020-08-01 00:00:00
abstract::Results from prospective surveillance of nosocomial infections (NIs) in a small community hospital were evaluated, and a case-control study was conducted. The rate of 1.4 NIs per 100 discharges determined by prospective surveillance was found to be underestimated. Prematurity, pediatric service, surgery, length of sta...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501920
更新日期:2001-06-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/521654
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:The incidence of extended-spectrum beta-lactamase (ESbetaL)-mediated resistance has increased markedly during the past decade. Risk factors for colonization with ESbetaL-producing Escherichia coli and Klebsiella species (ESbetaL-EK) remain unclear, as do methods to control their further emergence. DESIGN:Cas...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502045
更新日期:2002-05-01 00:00:00