3-Methyl-4-chlorophenol for prion decontamination of medical devices.

Abstract:

:Disinfectants containing 3-methyl-4-chlorophenol were tested for their capacity to inactivate the infectious agent of scrapie. Coincubation of brain homogenates prepared from terminally ill scrapie-infected hamsters with the disinfectants rendered the prion protein PrP(Sc) sensitive to proteinase K digestion. Inoculation of hamsters with disinfectant-treated samples indicated a reduction in infectivity levels to below the limit of detection.

authors

Riemer C,Bamme T,Mok SW,Baier M

doi

10.1086/504450

subject

Has Abstract

pub_date

2006-07-01 00:00:00

pages

778-80

issue

7

eissn

0899-823X

issn

1559-6834

pii

ICHE2005240

journal_volume

27

pub_type

杂志文章
  • Epidemiological and genetic characterization of Clostridium butyricum cultured from neonatal cases of necrotizing enterocolitis in China.

    abstract:OBJECTIVE:Laboratory-based characterization and traceback of Clostridium butyricum isolates linked to outbreak cases of neonatal necrotizing enterocolitis (NEC) in a hospital in China. METHODS:In total, 37 samples were collected during the NEC outbreak. Classical bacteriological methods were applied to isolate and ide...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2019.289

    authors: Dong Y,Li Y,Zhang D,Nguyen S,Maheshwari N,Hu Y,Cao Y,Li F,Fanning S

    更新日期:2020-08-01 00:00:00

  • Controlling use of antimicrobials in a community teaching hospital.

    abstract:OBJECTIVE:To test the hypothesis that antibiotic use could be controlled or improved in a community teaching hospital, with improvement defined as reductions in overall use, overall cost, and antimicrobial resistance. DESIGN:Interventional study with historical comparison. SETTING:A not-for-profit, 900-bed community ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/500419

    authors: Philmon C,Smith T,Williamson S,Goodman E

    更新日期:2006-03-01 00:00:00

  • Effectiveness of hand-cleansing agents for removing methicillin-resistant Staphylococcus aureus from contaminated hands.

    abstract:OBJECTIVE:The effectiveness of hand-cleansing agents in removing a hospital strain of methicillin-resistant Staphylococcus aureus from artificially contaminated hands of five volunteers was studied. DESIGN:The products used were plain liquid soap, ethyl alcohol 70% (by weight), 10% povidone-iodine liquid soap (PVP-I),...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1086/501872

    authors: Guilhermetti M,Hernandes SE,Fukushigue Y,Garcia LB,Cardoso CL

    更新日期:2001-02-01 00:00:00

  • Nosocomial infection due to Vibrio cholerae in two referral hospitals in Guatemala.

    abstract::We report nosocomial infection with Vibrio cholerae 01, in four seriously ill individuals and one infant in Guatemala. Nosocomial cholera occurs in developing countries in Latin America and should be suspected in hospitalized patients with diarrhea, especially during community outbreaks, in order to institute appropri...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647321

    authors: Hernández JE,Mejía CR,Cazali IL,Arathoon EG

    更新日期:1996-06-01 00:00:00

  • Methicillin resistance and risk factors for embolism in Staphylococcus aureus infective endocarditis.

    abstract:OBJECTIVE:Infective endocarditis caused by Staphylococcus aureus is an ominous prognosis associated with a high prevalence of embolic episodes and neurological involvement. Whether methicillin resistance decreases the risk of embolism in infective endocarditis is unclear. We sought to assess the association between met...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/518727

    authors: Hsu RB,Lin FY

    更新日期:2007-07-01 00:00:00

  • Colonization with extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species in long-term care facility residents.

    abstract::We describe the prevalence of and risk factors for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-EB) in the long-term care facility (LTCF) setting. Colonization prevalence differed significantly across the 3 LTCFs evaluated in the study, with recent use of levofloxacin and fecal in...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1086/664055

    authors: Lautenbach E,Han J,Santana E,Tolomeo P,Bilker WB,Maslow J

    更新日期:2012-03-01 00:00:00

  • Electronic solutions to enhance tracking and compliance with mandatory influenza vaccination for all hospital staff.

    abstract::In implementing a hospital mandatory influenza vaccination policy, we developed an automated, real-time tracking and reminder system. Of 6,957 policy-covered individuals automatically identified, automated reminders left only 5 requiring counseling. This decreased Occupational Health workload in contacting noncomplian...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/678415

    authors: Quan KA,Cousins SM,Hizon DA,Heck KK,Samuelson P,Garcia F Jr,Huang SS

    更新日期:2014-11-01 00:00:00

  • Cleaning and sterilization protocol for reused cardiac electrophysiology catheters inactivates hepatitis and coxsackie viruses.

    abstract:OBJECTIVE:To assess the efficacy of a standard cleaning and sterilization protocol employed during reuse of cardiac electrophysiology catheters on the infectivity of duck hepatitis B virus (DHBV; a surrogate for human hepatitis B virus), bovine viral diarrhea virus (BVDV; a surrogate for human hepatitis C virus), and h...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502609

    authors: Druce JD,Russell JS,Birch CJ,Vickery K,Harper RW,Smolich JJ

    更新日期:2005-08-01 00:00:00

  • The effect of leadership on hand hygiene: assessing hand hygiene adherence prior to patient contact in 2 infectious disease units in Tuscany.

    abstract::We assessed hand hygiene adherence in 2 infectious disease units. In one unit, adherence declined slightly from year 1 (84.2%) to year 4 (71.0%) after a multimodal intervention but remained much higher than before intervention. Adherence dropped in the second unit after a loss of leadership (from 50.7% to 5.7%). Stron...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/675296

    authors: Lieber SR,Mantengoli E,Saint S,Fowler KE,Fumagalli C,Bartolozzi D,Magistri L,Niccolini F,Bartoloni A

    更新日期:2014-03-01 00:00:00

  • Influenza vaccination and intention to receive the pandemic H1N1 influenza vaccine among healthcare workers of British Columbia, Canada: a cross-sectional study.

    abstract:OBJECTIVE:To assess healthcare workers' attitudes and concerns regarding seasonal and pandemic influenza vaccines in order to improve vaccination campaign communications. DESIGN:Cross-sectional survey. SETTING:All 6 health authorities in British Columbia, Canada. METHODS:An anonymous, self-administered online survey...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/655465

    authors: Kaboli F,Astrakianakis G,Li G,Guzman J,Donovan T,Naus M

    更新日期:2010-10-01 00:00:00

  • The epidemiology of fecal carriage of vancomycin-resistant enterococci.

    abstract::An outbreak of vancomycin-resistant enterococci (VRE) began at the University of Massachusetts Medical Center in May 1993. As of September 1995, we had a total of 253 patients infected or colonized with VRE, with consequent increasing demand for private rooms. We analyzed results of surveillance cultures for VRE of 49...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:

    authors: Lai KK,Fontecchio SA,Kelley AL,Melvin ZS,Baker S

    更新日期:1997-11-01 00:00:00

  • Evaluation of a rapid readout biological indicator for flash sterilization with three biological indicators and three chemical indicators.

    abstract:OBJECTIVE:Flash sterilization is most commonly used for emergency sterilization of unwrapped items in a gravity displacement sterilizer for three minutes. Sterilization quality assurance is monitored by biological indicators that require a 24-hour incubation prior to reading. In this study, we compared a new biological...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646767

    authors: Rutala WA,Gergen MF,Weber DJ

    更新日期:1993-07-01 00:00:00

  • Inpatient antibiotic utilization in the Veterans' Health Administration during the coronavirus disease 2019 (COVID-19) pandemic.

    abstract::Antibiotic prescribing practices across the Veterans' Health Administration (VA) experienced significant shifts during the coronavirus disease 2019 (COVID-19) pandemic. From 2015 to 2019, antibiotic use between January and May decreased from 638 to 602 days of therapy (DOT) per 1,000 days present (DP), while the corre...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.1277

    authors: Dieringer TD,Furukawa D,Graber CJ,Stevens VW,Jones MM,Rubin MA,Goetz MB

    更新日期:2020-10-20 00:00:00

  • Methicillin‐resistant Staphylococcus aureus and the media.

    abstract::How the media communicate and how the scientific community influences the media are important factors to consider in the public health response to emerging pathogens, including methicillin-resistant Staphylococcus aureus. Social representation theory suggests that the media link "the threatening" to commonplace "ancho...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/656000

    authors: Perencevich EN,Treise DM

    更新日期:2010-11-01 00:00:00

  • Attributable costs of enterococcal bloodstream infections in a nonsurgical hospital cohort.

    abstract:BACKGROUND:Vancomycin-resistant Enterococcus (VRE) bloodstream infections (BSIs) are associated with increased morbidity and mortality. OBJECTIVE:To determine the hospital costs and length of stay attributable to VRE BSI and vancomycin-sensitive Enterococcus (VSE) BSI and the independent effect of vancomycin resistanc...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/649020

    authors: Butler AM,Olsen MA,Merz LR,Guth RM,Woeltje KF,Camins BC,Fraser VJ

    更新日期:2010-01-01 00:00:00

  • Epidemic of Serratia marcescens bacteremia and meningitis in a neonatal unit in Mexico City.

    abstract::A case-control study was conducted on an epidemic of bacteremia and meningitis caused by Serratia marcescens in the neonatal intensive care unit and special care nursery of a general hospital in Mexico City, Mexico. A 19.9% incidence of bacteremia and meningitis was recorded in contrast to 1.4% and 3.7% during preepid...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/645909

    authors: Zaidi M,Sifuentes J,Bobadilla M,Moncada D,Ponce de León S

    更新日期:1989-01-01 00:00:00

  • Lack of Comprehensive Outbreak Detection in Hospitals.

    abstract::Timely identification of outbreaks of hospital-associated infections is needed to implement control measures and minimize impact. Survey results from 33 hospitals indicated that most hospitals lacked a formal cluster definition and all targeted a very limited group of prespecified pathogens. Standardized, statisticall...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1017/ice.2015.325

    authors: Baker MA,Huang SS,Letourneau AR,Kaganov RE,Peeples JR,Drees M,Platt R,Yokoe DS

    更新日期:2016-04-01 00:00:00

  • Long-term outcomes of an antimicrobial stewardship program implemented in a hospital with low baseline antibiotic use.

    abstract:OBJECTIVE:To evaluate the long-term outcomes of an antimicrobial stewardship program (ASP) implemented in a hospital with low baseline antibiotic use. DESIGN:Quasi-experimental, interrupted time-series study. SETTING:Public safety net hospital with 525 beds. INTERVENTION:Implementation of a formal ASP in July 2008. ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2015.41

    authors: Jenkins TC,Knepper BC,Shihadeh K,Haas MK,Sabel AL,Steele AW,Wilson ML,Price CS,Burman WJ,Mehler PS

    更新日期:2015-06-01 00:00:00

  • Prevalence of colonization with community-associated methicillin-resistant Staphylococcus aureus among end-stage renal disease patients and healthcare workers.

    abstract:OBJECTIVE:To evaluate the prevalence, epidemiologic features, and molecular characteristics of colonization with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) among hospitalized dialysis patients and their healthcare workers (HCWs). DESIGN:Prospective observational clinical and laboratory ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/592983

    authors: Johnson LB,Jose J,Yousif F,Pawlak J,Saravolatz LD

    更新日期:2009-01-01 00:00:00

  • Risk factors for fecal colonization with multiple distinct strains of Escherichia coli among long-term care facility residents.

    abstract::Of 49 long-term care facility residents, 21 (43%) were colonized with 2 or more distinct strains of Escherichia coli. There were no significant risk factors for colonization with multiple strains of E. coli. These results suggest that future efforts to efficiently identify the diversity of colonizing strains will be c...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/597234

    authors: Lautenbach E,Tolomeo P,Black N,Maslow JN

    更新日期:2009-05-01 00:00:00

  • Elution efficiency of healthcare pathogens from environmental sampling tools.

    abstract::Standardizing healthcare surface sampling requires the evaluation of sampling tools for organism adherence. Here, 7 sampling tools were evaluated to assess their elution efficiencies in the presence of 5 pathogens. Foam sponges (80.6%), microfiber wipes (80.5%), foam swabs (77.9%), and cellulose sponges (66.5%) yielde...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2019.264

    authors: West-Deadwyler RM,Moulton-Meissner HA,Rose LJ,Noble-Wang JA

    更新日期:2020-02-01 00:00:00

  • The role played by contaminated surfaces in the transmission of nosocomial pathogens.

    abstract::Studies in the 1970s and 1980s suggested that environmental surface contamination played a negligible role in the endemic transmission of healthcare-associated infections. However, recent studies have demonstrated that several major nosocomial pathogens are shed by patients and contaminate hospital surfaces at concent...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/660363

    authors: Otter JA,Yezli S,French GL

    更新日期:2011-07-01 00:00:00

  • Positive deviance: a new strategy for improving hand hygiene compliance.

    abstract:OBJECTIVE:To evaluate the effectiveness of a positive deviance strategy for the improvement of hand hygiene compliance in 2 adult step-down units. DESIGN:A 9-month, controlled trial comparing the effect of positive deviance on compliance with hand hygiene. SETTING:Two 20-bed step-down units at a tertiary care private...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/649224

    authors: Marra AR,Guastelli LR,de Araújo CM,dos Santos JL,Lamblet LC,Silva M Jr,de Lima G,Cal RG,Paes AT,Cendoroglo Neto M,Barbosa L,Edmond MB,dos Santos OF

    更新日期:2010-01-01 00:00:00

  • Effect of prospective audit and feedback on inpatient fluoroquinolone use and appropriateness of prescribing.

    abstract::We report the effect of prospective audit and feedback (PAF) on inpatient fluoroquinolone (FQN) prescriptions. During the PAF period, FQN use decreased from 39.19 to 29.58 days of therapy per 1,000 patient days (P < .001) and appropriateness improved from 68% to 88% (P < .001). High-yield indications to target include...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.339

    authors: Marek CM,Zurek KJ,Degenhardt O,Remtulla S,Teale AS,Cervera C,Hoang HL

    更新日期:2020-12-01 00:00:00

  • Nosocomial dermatitis caused by Dermanyssus gallinae.

    abstract::The mite Dermanyssus gallinae may cause pruritic dermatitis in humans. We describe a case of nosocomial infestation with D. gallinae from an abandoned pigeon nest suspended on the front wall of the Hôpital Henri Mondor near a window. Close surveillance and regular destruction of pigeon nests could prevent these incide...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/528815

    authors: Bellanger AP,Bories C,Foulet F,Bretagne S,Botterel F

    更新日期:2008-03-01 00:00:00

  • Malaria: protection of the international traveler.

    abstract::Thorough counseling with emphasis on the importance of mosquito bite avoidance, as well as on compliance with prophylactic antimalarial regimens, remains an important task for the physician preparing a patient for international travel. Chloroquine continues to be the drug of choice for prophylaxis in areas not reporti...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/646703

    authors: Rangel-Frausto MS,Edmond MB

    更新日期:1993-03-01 00:00:00

  • Nosocomial transmission of HIV in Africa: what tribute is paid to contaminated blood transfusions and medical injections?

    abstract::We reviewed the published data on the possible impact of medical injections and blood transfusions on the spread of human immunodeficiency virus (HIV) in Africa. We also compared these results to our experience in Rwanda, central Africa. The importance of medical injections in the epidemic of HIV infection seems to di...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/645833

    authors: Lepage P,Van de Perre P

    更新日期:1988-05-01 00:00:00

  • Unnecessary antibiotic prescribing in pediatric ambulatory care visits for bronchitis and bronchiolitis in the United States, 2006-2015.

    abstract::Antibiotics are not indicated for the treatment of bronchitis and bronchiolitis. Using a nationally representative database from 2006-2015, we found that antibiotics were prescribed in 58% of outpatient visits for bronchitis and bronchiolitis in children, serving as a possible baseline for the expanded HEDIS 2020 meas...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.1231

    authors: Snyder RL,King LM,Hersh AL,Fleming-Dutra KE

    更新日期:2020-10-16 00:00:00

  • Decontamination of an Extracorporeal Membrane Oxygenator Contaminated With Mycobacterium chimaera.

    abstract::Water samples taken from extracorporeal membrane oxygenator (ECMO) devices used at University Hospitals Birmingham yielded high total viable counts (TVCs) containing a variety of microorganisms, including M. chimaera. Disinfection resulted in the reduction of TVCs and eradication of Mycobacterium chimaera. Weekly disi...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2017.163

    authors: Garvey MI,Phillips N,Bradley CW,Holden E

    更新日期:2017-10-01 00:00:00

  • The time burden of alcohol-based hand cleanser when using nonsterile gloves.

    abstract::We quantified the time burden of alcohol-based handrub accompanying nonsterile-glove use among emergency physicians, through observation in controlled and clinical settings. We report gloving episodes per hour, gloving times with and without handrub, and handrub recommendations compliance. Handrub adds 46 seconds to e...

    journal_title:Infection control and hospital epidemiology

    pub_type: 临床试验,杂志文章

    doi:10.1086/668781

    authors: Reardon JM,Valenzuela JE,Parmar S,Venkatesh AK,Schuur JD,Allen MB,Pallin DJ

    更新日期:2013-01-01 00:00:00