Abstract:
OBJECTIVE:To assess the diagnostic value of an adenosinetriphosphate bioluminescence assay (ATPmetry) to monitor the effectiveness of the reprocessing of endoscopes compared with microbiologic sampling. DESIGN:Diagnostic study. SETTING:A 2,200-bed teaching hospital performing 5,000 to 6,000 endoscopic procedures annually. INCLUSION CRITERIA:All samples from bronchial or gastrointestinal endoscopes whatever the context. METHODS:Samples for microbiologic analysis and ATPmetry measurements were taken when each endoscope was inspected following reprocessing. Sampling was performed by flushing each endoscope with 300 mL Neutralizing Pharmacopeia Diluent thiosulfate rinsing solution divided equally between the endoscope channels. For each endoscope a series of 3 ATPmetry measurements were made on a vial containing the first jet from each channel and a second series on the whole sample. RESULTS:Of 165 samples from endoscopes, 11 exceeded the acceptability threshold of 25 colony-forming units/endoscope. In the first jet collected, the median (interquartile range) level of ATPmetry was 30.5 (15.3-37.7) relative light units (RLU) for samples with 25 or fewer colony-forming units compared with 37.0 (34.7-39.3) RLU for samples with more than 25 colony-forming units (P=.008). For the whole sample, the median (interquartile range) level of ATPmetry was 24.8 (14.3-36.3) RLU and 36.3 (36.0-38.3) RLU (P=.006), respectively. After adjusting on the batch of cleansing solution used, no difference in ATPmetry values was found between microbiologically acceptable and unacceptable samples. CONCLUSION:ATPmetry cannot be used as an alternative or complementary approach to microbiologic tests for monitoring the reprocessing of endoscopes in France.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Batailler P,Saviuc P,Picot-Gueraud R,Bosson JL,Mallaret MRdoi
10.1017/ice.2015.212subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1437-43issue
12eissn
0899-823Xissn
1559-6834pii
S0899823X15002123journal_volume
36pub_type
杂志文章abstract::An intensive care nurse with eczema was repeatedly treated for methicillin-resistant Staphylococcus aureus (MRSA) carriage. Because cultures remained positive for MRSA, her house was investigated. Thirty-four percent of environmental samples yielded MRSA. Her children and cat were free of MRSA. The house was decontami...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/507966
更新日期:2006-10-01 00:00:00
abstract::We investigated surgical site infections (SSIs) following hip and knee arthroplasties to evaluate predictors of SSI. We found a significant increase in deep Staphylococcus aureus (SA) SSIs despite the decreasing overall SSI rate. The risk of deep SA-SSI differed between genders and among age groups and was affected by...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1017/ice.2018.312
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:An epidemiological investigation was conducted to determine risk factors for adverse reactions among patients in hospitals and the possibility of extrinsic or intrinsic contamination of intravenous solutions. DESIGN:A retrospective cohort study was conducted to identify solutions associated with adverse reac...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/504360
更新日期:2006-07-01 00:00:00
abstract::We used a survey to characterize contemporary infection prevention and antibiotic stewardship program practices across 64 healthcare facilities, and we compared these findings to those of a similar 2013 survey. Notable findings include decreased frequency of active surveillance for methicillin-resistant Staphylococcus...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1017/ice.2019.172
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Peripheral venous catheters (PVCs) can be associated with serious infectious complications. We evaluated the effect of education and feedback on process measures to improve PVC care and infectious complications. DESIGN:Quasi-experimental controlled crossover study with sampling before and aft...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1086/665322
更新日期:2012-05-01 00:00:00
abstract::Over a 1-week period, Neisseria meningitidis serogroup B was recovered from two patients in the intensive-care unit (ICU). A cross-infection was presumed when one patient developed invasive meningococcal disease and another patient was found to be colonized. Investigation by molecular typing showed that these cases we...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647589
更新日期:1997-03-01 00:00:00
abstract::Annual surveillance data (2007-2015), collected continuously in 132 German hospitals, was evaluated for development of alcohol-based hand-rub consumption (AHC) as a surrogate parameter for hand hygiene adherence. Overall, the median increase in AHC was 94%. The increases over 9 years were significant in all units and ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.71
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:Surgical site infections (SSIs) are responsible for significant morbidity and mortality. Preadmission skin antisepsis, while controversial, has gained acceptance as a strategy for reducing the risk of SSI. In this study, we analyze the benefit of an electronic alert system for enhancing compliance to preadmis...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/ice.2015.303
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:To determine the rates of surgical-site infections (SSIs) after spinal surgery and to identify the risk factors associated with infection. DESIGN:SSIs had been identified by active prospective surveillance. A case-control study to identify risk factors was performed retrospectively. SETTING:University-asso...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502259
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:States, including Illinois, have passed legislation mandating the use of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for reporting healthcare-associated infections, such as methicillin-resistant Staphylococcus aureus (MRSA). OBJECTIVE:To evaluate the sens...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/651665
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To determine the frequency and type of nosocomial infections (NIs) (especially surgical-site infections [SSIs]), risk factors, and the type and duration of antibiotic use among surgical patients in Greek hospitals. DESIGN:Two point-prevalence studies. SETTING:Fourteen Greek hospitals. PATIENTS:Those in the...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/502399
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:To determine persistence of coagulase-negative staphylococci (CNS) on a hematology-oncology ward and to determine the value of phenotypic and genotypic procedures for establishing clonality among CNS isolates. DESIGN:Strains of CNS isolated from bacteremic patients (n = 139) were typed by biochemical reactiv...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Observational studies compare outcomes among subjects with and without an exposure of interest, without intervention from study investigators. Observational studies can be designed as a prospective or retrospective cohort study or as a case-control study. In healthcare epidemiology, these observational studies often t...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1017/ice.2016.118
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The device standardized infection ratio (SIR) is used to compare unit and hospital performance for different publicly reported infections. Interventions to reduce unnecessary device use may select a higher-risk population, leading to a paradoxical increase in SIR for some high-performing facilities. The stan...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.175
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:We evaluated the usefulness of topical decolonization therapy for reducing the risk of methicillin-resistant Staphylococcus aureus (MRSA) infection among MRSA-colonized inpatients. DESIGN:Retrospective cohort study. SETTING AND INTERVENTION:Three hospitals with universal surveillance for MRSA; at their phys...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597550
更新日期:2009-07-01 00:00:00
abstract::During an insidious outbreak of salmonellosis in a long-term care facility, residents who were treated with acid-suppressing medications were 8 times more likely than other residents to develop Salmonella infection. Among vulnerable populations, the risks and benefits of acid-suppressing medications should be consider...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/520736
更新日期:2007-10-01 00:00:00
abstract::In implementing a hospital mandatory influenza vaccination policy, we developed an automated, real-time tracking and reminder system. Of 6,957 policy-covered individuals automatically identified, automated reminders left only 5 requiring counseling. This decreased Occupational Health workload in contacting noncomplian...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/678415
更新日期:2014-11-01 00:00:00
abstract::OBJECTIVE To define how often methicillin-resistant Staphylococcus aureus (MRSA) is spread from resident to resident in long-term care facilities using whole-genome sequencing DESIGN Prospective cohort study SETTING A long-term care facility PARTICIPANTS Elderly residents in a long-term care facility METHODS Cultures ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.41
更新日期:2016-06-01 00:00:00
abstract::A patient with no risk factors for malaria was hospitalized in New York City with Plasmodium falciparum infection. After investigating all potential sources of infection, we concluded the patient had been exposed to malaria while hospitalized less than 3 weeks earlier. Molecular genotyping implicated patient-to-patien...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.236
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Case-control studies analyzing antibiotic exposure as a risk factor for antimicrobial resistance usually assume single-drug resistance in the bacteria under study, even though resistance to multiple antimicrobials may be present. Since antibiotic selection pressures differ depending on the susceptibility pro...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/505917
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of central venous catheter (CVC) use among patients both within and outside the ICU setting. DESIGN:A 1-day prevalence survey of CVC use among adult inpatients at six medical centers participating in the Prevention Epicenter Program of the CDC. Using a standardized form, observers...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502163
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVE:Evaluate changes in antimicrobial use during COVID-19 and after implementation of a multispecialty COVID-19 clinical guidance team compared to pre-COVID-19 antimicrobial use. DESIGN:Retrospective observational study. SETTING:Tertiary-care academic medical center. PARTICIPANTS:Internal medicine and medical ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1291
更新日期:2020-10-26 00:00:00
abstract::This study reports an investigation of outbreaks of methicillin-resistant Staphylococcus aureus (MRSA) infection and colonization involving 17 newborns in the neonatal unit of a teaching hospital. A neonatal specialist colonized with MRSA that eventually became mupirocin-resistant was implicated as a recurrent source ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/513616
更新日期:2007-05-01 00:00:00
abstract::The prevalence of latent tuberculosis infection in a cohort of nurses new to a London hospital was 7.6% (13 of 171), using an interferon-gamma (IFN-gamma) release assay, and 16.2% (24 of 148), using the tuberculin skin test. On multivariate analysis, birth in a country with tuberculosis prevalence of more than 40 case...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597546
更新日期:2009-06-01 00:00:00
abstract::The hospital-wide attack rate for Clostridium difficile-associated diarrhea at our tertiary-care university hospital was 0.02 per 100 patient discharges (0.02%) in 1982, but 0.41% and 1.47% in 1986 and 1987, respectively, with a peak incidence of 2.25% in the fourth quarter of 1987. Hospital antibiotic usage patterns ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646173
更新日期:1990-06-01 00:00:00
abstract::Adults more than 40 years old are not necessarily immune to measles. A measles outbreak that involved healthcare workers occurred after contact with a 44-year-old patient. Results of a hospital-wide program of mass screening revealed that 117 (4.5%) of 2,600 individuals tested seronegative for measles; 31 (26.1%) of t...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/519928
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:The prevalence of vancomycin-resistant enterococci (VRE) has increased markedly during the past decade. Few data exist regarding the epidemiology of resistance of VRE to chloramphenicol, one of the few therapeutic options. DESIGN:Survey and case-control study. SETTING:A 725-bed, tertiary-care academic medic...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502365
更新日期:2004-02-01 00:00:00
abstract::Breathing circuit filters (BCFs) are used in respiratory and critical-care settings for humidification of air and to limit transmission of respiratory pathogens. Three types of BCFs (Pall BB 25A, BB 100, and HME 15-22) were evaluated (in triplicate) for removal of Mycobacterium species. Filters were challenged with ae...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647606
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence, risk factors, and outcomes of nosocomial infection due to antimicrobial resistant bacteria in patients treated in the pediatric intensive care unit (PICU). DESIGN:Nested case-cohort study. Patient data were collected prospectively, and antimicrobial susceptibility data were abstr...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/512628
更新日期:2007-03-01 00:00:00
abstract::OBJECTIVE Contaminated hands of healthcare workers (HCWs) are an important source of transmission of healthcare-associated infections. Alcohol-based hand sanitizers, while effective, do not provide sustained antimicrobial activity. The objective of this study was to compare the immediate and persistent activity of 2 h...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/ice.2017.293
更新日期:2018-03-01 00:00:00