Monitoring persistence of coagulase-negative staphylococci in a hematology department using phenotypic and genotypic strategies.

Abstract:

OBJECTIVE:To determine persistence of coagulase-negative staphylococci (CNS) on a hematology-oncology ward and to determine the value of phenotypic and genotypic procedures for establishing clonality among CNS isolates. DESIGN:Strains of CNS isolated from bacteremic patients (n = 139) were typed by biochemical reactivity, antibiotic susceptibility, DNA macrorestriction analysis by pulsed-field gel electrophoresis (PFGE), and arbitrary primed polymerase chain reaction (AP PCR). Coagulase-negative staphylococci were subgrouped in a random collection (n = 20) used for the evaluation of the typing procedures and a collection of 119 CNS isolates from hematologic patients displaying multiple bacteremic episodes. RESULTS:Analysis of the reference collection demonstrated the usefulness of the DNA typing procedures, indicating that AP PCR and PFGE can be used for epidemiologic typing of CNS in a concordant fashion. Certain strains appeared to be permanent colonizers of the hematology ward or ward-related personnel. In individual patients, persistent colonization by a single type was demonstrated. However, a number of patients also experienced bacteremic episodes caused by CNS belonging to different types. CONCLUSION:We conclude that monitoring of CNS infections on a hematology ward by various genotypic techniques provides insight into nosocomial epidemiology and elucidates the complexity of the infections taking place. DNA typing is preferred over phenotypic procedures and can identify persistent CNS strains in a given location.

authors

van Belkum A,Kluijtmans J,van Leeuwen W,Goessens W,ter Averst E,Wielenga J,Verbrugh H

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

660-7

issue

10

eissn

0899-823X

issn

1559-6834

pii

S0195941700002964

journal_volume

17

pub_type

杂志文章
  • Handwashing and glove use in a long-term-care facility.

    abstract:OBJECTIVES:To determine glove use and handwashing practices, the factors associated with infection control practices, and the frequency of potential microbial transmission in a long-term-care facility (LTCF). DESIGN:Observational study of 230 staff-resident interactions in an LTCF. We recorded resident characteristics...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647562

    authors: Thompson BL,Dwyer DM,Ussery XT,Denman S,Vacek P,Schwartz B

    更新日期:1997-02-01 00:00:00

  • Risk factors for Clostridium difficile toxin-associated diarrhea.

    abstract::The hospital-wide attack rate for Clostridium difficile-associated diarrhea at our tertiary-care university hospital was 0.02 per 100 patient discharges (0.02%) in 1982, but 0.41% and 1.47% in 1986 and 1987, respectively, with a peak incidence of 2.25% in the fourth quarter of 1987. Hospital antibiotic usage patterns ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646173

    authors: Brown E,Talbot GH,Axelrod P,Provencher M,Hoegg C

    更新日期:1990-06-01 00:00:00

  • Trends in Clostridium difficile infection among peripartum women.

    abstract::With use of the Nationwide Inpatient Sample, we conducted a study to determine whether rates of Clostridium difficile infection for delivery-associated hospitalizations are increasing. From 1998 to 2006, the number and incidence of C. difficile infection among peripartum women increased significantly. These increases ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/652454

    authors: Kuntz JL,Yang M,Cavanaugh J,Saftlas AF,Polgreen PM

    更新日期:2010-05-01 00:00:00

  • Comparative Antimicrobial Efficacy of Two Hand Sanitizers in Intensive Care Units Common Areas: A Randomized, Controlled Trial.

    abstract::OBJECTIVE Contaminated hands of healthcare workers (HCWs) are an important source of transmission of healthcare-associated infections. Alcohol-based hand sanitizers, while effective, do not provide sustained antimicrobial activity. The objective of this study was to compare the immediate and persistent activity of 2 h...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/ice.2017.293

    authors: Deshpande A,Fox J,Wong KK,Cadnum JL,Sankar T,Jencson A,Schramm S,Fraser TG,Donskey CJ,Gordon S

    更新日期:2018-03-01 00:00:00

  • Outbreak of vancomycin-resistant enterococci in a burn unit.

    abstract:OBJECTIVE:To investigate and control an outbreak of colonization and infection caused by vancomycin-resistant enterococci (VRE) in a burn intensive care unit (BICU). DESIGN:Epidemiological investigation, including multiple point-prevalence culture surveys of patients and environment, cultures from hands of healthcare ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/501806

    authors: Falk PS,Winnike J,Woodmansee C,Desai M,Mayhall CG

    更新日期:2000-09-01 00:00:00

  • Blood pressure cuff as a potential vector of pathogenic microorganisms: a prospective study in a teaching hospital.

    abstract:OBJECTIVE:To investigate the potential role of blood pressure (BP) cuffs in the spread of bacterial infections in hospitals. DESIGN:A comprehensive, prospective study quantitatively and qualitatively evaluating the bacterial contamination on BP cuffs of 203 sphygmomanometers in use in 18 hospital units from January th...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/507284

    authors: de Gialluly C,Morange V,de Gialluly E,Loulergue J,van der Mee N,Quentin R

    更新日期:2006-09-01 00:00:00

  • Hand hygiene noncompliance and the cost of hospital-acquired methicillin-resistant Staphylococcus aureus infection.

    abstract:BACKGROUND:Hand hygiene noncompliance is a major cause of nosocomial infection. Nosocomial infection cost data exist, but the effect of hand hygiene noncompliance is unknown. OBJECTIVE:To estimate methicillin-resistant Staphylococcus aureus (MRSA)-related cost of an incident of hand hygiene noncompliance by a healthca...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/651096

    authors: Cummings KL,Anderson DJ,Kaye KS

    更新日期:2010-04-01 00:00:00

  • Modeling transmission of methicillin-resistant Staphylococcus aureus among patients admitted to a hospital.

    abstract:OBJECTIVE:To determine the impact of the screening test, nursing workload, handwashing rates, and dependence of handwashing on risk level of patient visit on methicillin-resistant Staphylococcus aureus (MRSA) transmission among hospitalized patients. SETTING:General medical ward. METHODS:Monte Carlo simulation was us...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502589

    authors: Raboud J,Saskin R,Simor A,Loeb M,Green K,Low DE,McGeer A

    更新日期:2005-07-01 00:00:00

  • Local antibiotic prophylaxis in surgery.

    abstract::The perioperative use of antibiotics is an established and accepted technique for the prevention of postoperative infection. Intravenous administration often is preferred, and intramuscular administration is possible, although it has certain drawbacks. This article examines a variety of other routes of administration ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/647366

    authors: Martin C,Viviand X,Potié F

    更新日期:1996-08-01 00:00:00

  • An outbreak of imipenem-resistant Acinetobacter baumannii in critically ill surgical patients.

    abstract:OBJECTIVE:To describe an outbreak of imipenem-resistant Acinetobacter baumannii (IR-Ab) and the measures for its control, and to investigate risk factors for IR-Ab acquisition. DESIGN:An observational and a case-control study. SETTING:A surgical intensive care unit (ICU) in a university tertiary care hospital. METHO...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/501822

    authors: Fierobe L,Lucet JC,Decré D,Muller-Serieys C,Deleuze A,Joly-Guillou ML,Mantz J,Desmonts JM

    更新日期:2001-01-01 00:00:00

  • Nursing home outbreak of influenza A (H3N2): evaluation of vaccine efficacy and influenza case definitions.

    abstract:OBJECTIVES:Describe an outbreak of influenza A (H3N2); provide an analysis of vaccine efficacy; measure the sensitivity, specificity, and positive predictive value of 3 clinical case definitions of influenza. SETTING:A nursing home in Washington County, Maryland. The outbreak involved 52 residents (attack rate = 47.7%...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646479

    authors: Taylor JL,Dwyer DM,Coffman T,Groves C,Patel J,Israel E

    更新日期:1992-02-01 00:00:00

  • Association between climate and Enterobacter colonization in Swedish neonatal units.

    abstract:OBJECTIVE:To study risk factors for the highly variable local colonization rates with unrelated Enterobacter species strains previously found in 22 Swedish neonatal units (0% to 32.4% of the infants). PATIENTS AND SETTING:The fecal Enterobacter species carriage rates among 953 infants in the 22 special-care neonatal u...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/646641

    authors: Fryklund BA,Tullus K,Burman LG

    更新日期:1993-10-01 00:00:00

  • Substantial shifts in ranking of California hospitals by hospital-associated methicillin-resistant Staphylococcus aureus infection following adjustment for hospital characteristics and case mix.

    abstract:BACKGROUND:States have established public reporting of hospital-associated (HA) infections-including those of methicillin-resistant Staphylococcus aureus (MRSA)-but do not account for hospital case mix or postdischarge events. OBJECTIVE:Identify facility-level characteristics associated with HA-MRSA infection admissio...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/678069

    authors: Tehrani DM,Phelan MJ,Cao C,Billimek J,Datta R,Nguyen H,Kwark H,Huang SS

    更新日期:2014-10-01 00:00:00

  • Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting.

    abstract:OBJECTIVE:To determine whether hydrogen peroxide vapor (HPV) decontamination can reduce environmental contamination with and nosocomial transmission of Clostridium difficile. DESIGN:A prospective before-after intervention study. SETTING:A hospital affected by an epidemic strain of C. difficile. INTERVENTION:Intensiv...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/589906

    authors: Boyce JM,Havill NL,Otter JA,McDonald LC,Adams NM,Cooper T,Thompson A,Wiggs L,Killgore G,Tauman A,Noble-Wang J

    更新日期:2008-08-01 00:00:00

  • Control of methicillin-resistant Staphylococcus aureus in a neonatal intensive-care unit: use of intensive microbiologic surveillance and mupirocin.

    abstract:OBJECTIVE:To describe the epidemiology and the interventions used to control two methicillin-resistant Staphylococcus aureus (MRSA) epidemics involving 46 infants with two fatalities in a neonatal intensive care unit (NICU). SETTING:A 50-bed, level III NICU in a university hospital. INTERVENTIONS:After traditional in...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/647285

    authors: Back NA,Linnemann CC Jr,Staneck JL,Kotagal UR

    更新日期:1996-04-01 00:00:00

  • High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies.

    abstract:BACKGROUND:Despite contact isolation precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA), MRSA infections are increasing in many countries. OBJECTIVE:To evaluate the role of a potential unrecognized reservoir of MRSA carried by patients in acute care wards, we determined the prevalence of ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502514

    authors: Lucet JC,Grenet K,Armand-Lefevre L,Harnal M,Bouvet E,Regnier B,Andremont A

    更新日期:2005-02-01 00:00:00

  • Variation in mortality rates among long-term care facilities for residents with lower respiratory tract infection.

    abstract:OBJECTIVE:To identify variables contributing to interfacility differences in mortality among residents of long-term care facilities who have lower respiratory tract infection. DESIGN:Multicenter, prospective, 1-year observational study. SETTING:Twenty-one long-term care facilities in 4 geographic areas of Canada. PA...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1086/590123

    authors: Nicolle LE,Mubareka S,Simor A,Liu B,McNeil S,Lewis D,Duckworth H,Cheang M,Loeb M

    更新日期:2008-08-01 00:00:00

  • Expanding roles of healthcare epidemiology and infection control in spite of limited resources and compensation.

    abstract:OBJECTIVE:Data on the resources and staff compensation of hospital epidemiology and infection control (HEIC) departments are limited and do not reflect current roles and responsibilities, including the public reporting of healthcare-associated infections. This study aimed to obtain information to assist HEIC profession...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/650199

    authors: Wright SB,Ostrowsky B,Fishman N,Deloney VM,Mermel L,Perl TM

    更新日期:2010-02-01 00:00:00

  • Using social media to disseminate research in infection prevention, hospital epidemiology, and antimicrobial stewardship.

    abstract::Social media, prevention of healthcare-associated infections (HAIs) and antimicrobial stewardship (ASP) each impact every area of medicine. Independently, each have power to change medicine, however, synergistically, the impact could be transformative. Given the profound clinical, financial, and public health impact o...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1017/ice.2019.231

    authors: Cawcutt KA,Marcelin JR,Silver JK

    更新日期:2019-11-01 00:00:00

  • Glutaraldehyde: current status and uses.

    abstract::Glutaraldehyde (pentanedial) is a dialdehyde that displays potent bactericidal, fungicidal, mycobactericidal, sporicidal, and virucidal activity. Pertinent to its activity is its interaction with amino groups in proteins and enzymes, but this simplistic statement masks the manner in which it inactivates various types ...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章,评审

    doi:10.1086/646845

    authors: Russell AD

    更新日期:1994-11-01 00:00:00

  • Influenza surveillance case definitions miss a substantial proportion of older adults hospitalized with laboratory-confirmed influenza: A report from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network.

    abstract:OBJECTIVE:Older adults often have atypical presentation of illness and are particularly vulnerable to influenza and its sequelae, making the validity of influenza case definitions particularly relevant. We sought to assess the performance of influenza-like illness (ILI) and severe acute respiratory illness (SARI) crite...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.22

    authors: Andrew MK,McElhaney JE,McGeer AA,Hatchette TF,Leblanc J,Webster D,Bowie W,Poirier A,Nichols MK,McNeil SA,Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance Network Investigators.

    更新日期:2020-05-01 00:00:00

  • Efficacy of infection control strategies to reduce transmission of vancomycin-resistant enterococci in a tertiary care hospital in Korea: a 4-year follow-up study.

    abstract::To determine the effectiveness of infection control strategies to reduce transmission of vancomycin-resistant enterococci (VRE), a cohort study was performed in a university hospital. Contact precautions alone were not effective in reducing transmission of VRE. Strict isolation of affected patients in private rooms, i...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/513024

    authors: Yoonchang SW,Peck KR,Kim OS,Lee JH,Lee NY,Oh WS,Song JH

    更新日期:2007-04-01 00:00:00

  • Secular trends of candidemia in a large tertiary-care hospital from 1988 to 2000: emergence of Candida parapsilosis.

    abstract:OBJECTIVE:To analyze the secular trends of candidemia in a large tertiary-care hospital to determine the overall incidence, as well as the incidence by ward and by species, and to detect the occurrence of outbreaks. DESIGN:Retrospective descriptive analysis. Secular trends were calculated using the Mantel-Haenszel tes...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/502582

    authors: San Miguel LG,Cobo J,Otheo E,Sánchez-Sousa A,Abraira V,Moreno S

    更新日期:2005-06-01 00:00:00

  • Compliance with personal precautions against exposure to bloodborne pathogens among laboratory workers: a Canadian survey .

    abstract::A survey was conducted in laboratories across Canada to determine rates of compliance with recommended safety precautions against exposure to bloodborne pathogens and the rationale for current behaviors. Laboratory workers reported high rates of exposure to bodily fluids and poor rates of compliance with personal prot...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/524325

    authors: Main CL,Carusone SC,Davis K,Loeb M

    更新日期:2008-01-01 00:00:00

  • Effectiveness of multifaceted hospitalwide quality improvement programs featuring an intervention to remove unnecessary urinary catheters at a tertiary care center in Thailand.

    abstract:OBJECTIVE:To evaluate the efficacy of a multifaceted hospitalwide quality improvement program that featured an intervention to remind physicians to remove unnecessary urinary catheters. METHODS:A hospitalwide preintervention-postintervention study was conducted over 2 years (July 1, 2004, through June 30, 2006). The i...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/518453

    authors: Apisarnthanarak A,Thongphubeth K,Sirinvaravong S,Kitkangvan D,Yuekyen C,Warachan B,Warren DK,Fraser VJ

    更新日期:2007-07-01 00:00:00

  • Effectiveness of Probiotic for Primary Prevention of Clostridium difficile Infection: A Single-Center Before-and-After Quality Improvement Intervention at a Tertiary-Care Medical Center.

    abstract::OBJECTIVETo evaluate probiotics for the primary prevention of Clostridium difficile infection (CDI) among hospital inpatients.DESIGNA before-and-after quality improvement intervention comparing 12-month baseline and intervention periods.SETTINGA 694-bed teaching hospital.INTERVENTIONWe administered a multispecies prob...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2018.76

    authors: Trick WE,Sokalski SJ,Johnson S,Bunnell KL,Levato J,Ray MJ,Weinstein RA

    更新日期:2018-07-01 00:00:00

  • Electronically Available Comorbid Conditions for Risk Prediction of Healthcare-Associated Clostridium difficile Infection.

    abstract::OBJECTIVE To analyze whether electronically available comorbid conditions are risk factors for Centers for Disease Control and Prevention (CDC)-defined, hospital-onset Clostridium difficile infection (CDI) after controlling for antibiotic and gastric acid suppression therapy use. PATIENTS Patients aged ≥18 years admit...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2018.10

    authors: Harris AD,Sbarra AN,Leekha S,Jackson SS,Johnson JK,Pineles L,Thom KA

    更新日期:2018-03-01 00:00:00

  • Ventilator-associated tracheobronchitis increases the length of intensive care unit stay.

    abstract:OBJECTIVE:To investigate prospectively the clinical course and risk factors for ventilator-associated tracheobronchitis (VAT) and the impact of VAT on intensive care unit (ICU) morbidity and mortality. DESIGN:Prospective cohort study. SETTING:University Hospital Larissa, Larissa, Greece. PATIENTS:Critical care patie...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/671274

    authors: Karvouniaris M,Makris D,Manoulakas E,Zygoulis P,Mantzarlis K,Triantaris A,Chatzi M,Zakynthinos E

    更新日期:2013-08-01 00:00:00

  • Comorbidity and severity-of-illness risk adjustment for hospital-onset Clostridioides difficile infection using data from the electronic medical record.

    abstract:OBJECTIVE:To determine whether electronically available comorbidities and laboratory values on admission are risk factors for hospital-onset Clostridioides difficile infection (HO-CDI) across multiple institutions and whether they could be used to improve risk adjustment. PATIENTS:All patients at least 18 years of age...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1017/ice.2020.1344

    authors: Cabral SM,Goodman KE,Blanco N,Leekha S,Magder LS,Nadimpalli G,Pineles L,Thom KA,Harris AD

    更新日期:2020-12-17 00:00:00

  • Hand washing and physicians: how to get them together.

    abstract:OBJECTIVE:To determine the motivating and behavioral factors responsible for improving compliance with hand washing among physicians. DESIGN:Five unobtrusive, observational studies recording hand washing after direct patient contact, with study results reported to physicians. SETTING:A 450-bed hospital in a health ma...

    journal_title:Infection control and hospital epidemiology

    pub_type: 杂志文章

    doi:10.1086/501965

    authors: Salemi C,Canola MT,Eck EK

    更新日期:2002-01-01 00:00:00