Abstract:
:A mechanistic hypothesis for the origin of the three domains of life is proposed. A population of evolving pre-cells is suggested to have had a membrane of a racemate of chiral lipids that continuously underwent spontaneous symmetry breaking by spatial phase segregation into two enantiomerically enriched membrane domains. By frequent pre-cell fusions and fissions these membrane domains became partitioned between two pre-cell subpopulations having predominantly one lipid enantiomer or the other. The origin of the Bacteria and Archaea is explained by divergence of first a population of proto-bacteria and later a population of proto-archaea from the evolving pre-cells, each by the emergence of an enantio-selective lipid biosynthesis within the corresponding pre-cell subtype. The origin of the Eukarya is explained by symbiosis between a population of Bacteria and a subpopulation of pre-cells with a predominance of the bacteria-type lipid enantiomers.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
Wächtershäuser Gdoi
10.1046/j.1365-2958.2003.03267.xsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
13-22issue
1eissn
0950-382Xissn
1365-2958pii
3267journal_volume
47pub_type
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