Arterial distensibility in humans. Modulating mechanisms, alterations in diseases and effects of treatment.

abstract：BACKGROUND:Cardiac angiotensin AT1 receptors have been found in several animal species. In-vitro studies performed on cardiac preparations have shown that angiotensin II (ANG II) exerts a positive inotropic effect; however, in-vivo results have allowed no definitive conclusion to be drawn. The reasons behind these cont...

journal_title：Journal of hypertension

authors： Marano G,Formigari R,Vergari A

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that combination therapy might be a powerful tool to reduce blood pressure variability (BPV) in the treatment of hypertension. METHODS:In chronic studies, male spontaneously hypertensive rats were given drugs in their rat chow for 18 weeks (n = 9 or 10 for each group of rats). Doses we...

journal_title：Journal of hypertension

authors： Xie HH,Shen FM,Xu LP,Han P,Miao CY,Su DF

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Blood pressure normally declines during the night ('dipping'); a blunted nocturnal decline is an important cardiovascular risk factor. Marriage may be associated with lower ambulatory blood pressure, although this may be confounded by socio-economic and dietary factors. We examined the association of marital ...

journal_title：Journal of hypertension

authors： Causland FR,Sacks FM,Forman JP

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:It is well known that among hypertensive patients, an increased left ventricular mass (LVM) is a powerful predictor of cardiovascular morbidity and mortality. However, the mechanisms underlying LVM in hypertension are not completely understood, as the absolute value of blood pressure and other risk factors a...

journal_title：Journal of hypertension

authors： Menni C,Boffi L,Cesana F,Viviani Anselmi C,Nava S,Bertola F,Blasio AM,Roncarati R,Trimarco V,Marino M,Trimarco B,Grassi G,Giannattasio C,Mancia G

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To verify the benefit of renin-angiotensin system blockade in hypertension, the effects of 24 weeks' losartan and ramipril treatment, both alone and in combination, on urinary albumin excretion (UAE) and circulating transforming growth factor beta1 (TGF beta1) have been evaluated in hypertensive subjects with...

journal_title：Journal of hypertension

authors： Scaglione R,Argano C,Corrao S,Di Chiara T,Licata A,Licata G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to compare the cardiovascular responses to behavioural stressors of three groups of adolescents who differed in blood pressure status across assessments. DESIGN:Casual blood pressure of adolescents who were identified as having elevated blood pressure during a school screen was re...

journal_title：Journal of hypertension

authors： Saab PG,Llabre MM,Ma M,DiLillo V,McCalla JR,Fernander-Scott A,Copen R,Gellman M,Schneiderman N

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Although an exaggerated systolic blood pressure (SBP) response to exercise is a predictor of future hypertension and cardiovascular mortality, the underlying mechanisms are not fully understood. We tested the hypothesis that an exaggerated SBP response is associated with carotid atherosclerosis in a cross-sec...

journal_title：Journal of hypertension

authors： Jae SY,Fernhall B,Heffernan KS,Kang M,Lee MK,Choi YH,Hong KP,Ahn ES,Park WH

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:To estimate the trend in arterial hypertension's prevalence, awareness, treatment, and control in Romania, starting from the latest national survey Study for the Evaluation of Prevalence of Hypertension and Cardiovascular Risk in Romania III that has a crucial importance for the development of prevention str...

journal_title：Journal of hypertension

authors： Dorobantu M,Tautu OF,Dimulescu D,Sinescu C,Gusbeth-Tatomir P,Arsenescu-Georgescu C,Mitu F,Lighezan D,Pop C,Babes K,Giuca A,Branza I,Udrescu M,Herdea V,Darabont R

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:A reduced cardiac output in chronic heart failure (CHF) evokes renal NaCl and water retention, and, therefore, activates mechanisms promoting natriuresis. Atrial natriuretic peptide (ANP) is one such factor. We hypothesized that another NaCl sensitive endogenous natriuretic factor, i.e., marinobufagenin (MBG...

journal_title：Journal of hypertension

authors： Fridman AI,Matveev SA,Agalakova NI,Fedorova OV,Lakatta EG,Bagrov AY

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the consistency between a randomly recruited Western European population and the participants of the Framingham Heart Study, with respect to the rates and determinants of progression to hypertension. METHODS:Among the non-hypertensive individuals enrolled in the Flemish Study on Environment, Gene...

journal_title：Journal of hypertension

authors： Zhang H,Thijs L,Kuznetsova T,Fagard RH,Li X,Staessen JA

更新日期：2006-09-01 00:00:00

abstract：CONTEXT:There is a growing prevalence of cardiovascular disease (CVD) risk factors in West Africa and among its migrants to industrialized countries. Despite this, no study has reviewed CVD risk factor prevalence among West Africans in Africa and industrialized countries. OBJECTIVE:To appraise studies on the prevalenc...

journal_title：Journal of hypertension

authors： Commodore-Mensah Y,Samuel LJ,Dennison-Himmelfarb CR,Agyemang C

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypert...

journal_title：Journal of hypertension

authors： Koton S,Tanne D,Grossman E

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Marfan syndrome (MFS) is an autosomal dominant genetic disorder characterized by aortic root dilation and dissection and an abnormal fibrillin-1 synthesis. In this observational study, we evaluated aortic stiffness in MFS and its association with ascending aorta diameters and fibrillin-1 genotype. METHODS:A ...

journal_title：Journal of hypertension

authors： Salvi P,Grillo A,Marelli S,Gao L,Salvi L,Viecca M,Di Blasio AM,Carretta R,Pini A,Parati G

更新日期：2018-01-01 00:00:00

abstract：DESIGN AND METHODS:Levels of dietary and serum potassium are thought to correlate inversely with vascular resistance and blood pressure. This study examined renal vascular resistance in perfused rat kidneys partially preconstricted with 10 micromol/ phenylephrine, quantifying changes in the resistance when levels of po...

journal_title：Journal of hypertension

authors： Murphy ME,Cohen DB

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence and risk markers of arterial hypertension in the context of a rapidly growing urbanization in Africa. DESIGN:A cross-sectional study was performed on a representative sample of inhabitants of Pikine, an urban suburb of Dakar, Senegal. METHODS:Blood pressure was measured by properly ...

journal_title：Journal of hypertension

authors： Astagneau P,Lang T,Delarocque E,Jeannee E,Salem G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Recent studies indicated that central SBP could be estimated by radial late-SBP (rSBP2) with a small disparity. However, most of these studies were conducted by SphygmoCor with a transfer function. The agreement between rSBP2 and central SBP was also tested in several invasive studies, but with inconsistent ...

journal_title：Journal of hypertension

authors： Zhang Y,Agnoletti D,Protogerou AD,Wang JG,Topouchian J,Salvi P,Safar ME,Blacher J

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:Current clinical guidelines of primary aldosteronism recommend adrenalectomy (AdX) for unilateral primary aldosteronism based on the studies showing the potential superiority of AdX over the medical treatment. However, since most medically treated cases consisted of bilateral primary aldosteronism and all su...

journal_title：Journal of hypertension

authors： Katabami T,Fukuda H,Tsukiyama H,Tanaka Y,Takeda Y,Kurihara I,Ito H,Tsuiki M,Ichijo T,Wada N,Shibayama Y,Yoshimoto T,Ogawa Y,Kawashima J,Sone M,Inagaki N,Takahashi K,Fujita M,Watanabe M,Matsuda Y,Kobayashi H,Shib

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:As a new category of blood pressure (BP) classification according to the Seventh Report of The Joint National Committee, prehypertension has aroused people's great concern in recent years due to its associations with increased incidence of cardiovascular disease. However, there is little information about th...

journal_title：Journal of hypertension

authors： Dong GH,Wang D,Liu MM,Liu YQ,Zhao Y,Yang M,Meng XJ,Tian S,Meng X,Zhang HY

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To review, on a genome-wide scale, a linkage result obtained in an earlier candidate gene analysis in this same study sample, and to look for other possible contributing genetic loci predisposing to hypertension in this population. DESIGN:An affected sibpair linkage study with highly polymorphic genetic mar...

journal_title：Journal of hypertension

authors： Perola M,Kainulainen K,Pajukanta P,Terwilliger JD,Hiekkalinna T,Ellonen P,Kaprio J,Koskenvuo M,Kontula K,Peltonen L

更新日期：2000-11-01 00:00:00

abstract：UNLABELLED:PURPOSE IDENTIFICATION: Inter-individual variability in blood pressure response to treatment is well documented, but a clinically useful means to distinguish responders from non-responders has been elusive. With the advent of new technologies and genomic knowledge, more investigators are seeking to identify ...

journal_title：Journal of hypertension

authors： Mellen PB,Herrington DM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:Mechanisms involved in hypertension in homozygous mice for the defective endothelial nitric oxide synthase gene (eNOS-/-) have not been fully elucidated. As NO is a potent vasodilator agent and possibly promotes angiogenesis, we investigated whether vasoconstriction and/or microvascular rarefaction could exp...

journal_title：Journal of hypertension

authors： Kubis N,Richer C,Domergue V,Giudicelli JF,Lévy BI

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To determine the plasma cofactor which is required by diuretics (hydrochlorothiazide, chlorthalidone, indapamide, and furosemide) for direct vasorelaxant effects in vitro. DESIGN:A randomized, double-blind, vehicle-control design was used to avoid experimenter bias. METHODS:We plotted concentration-response...

journal_title：Journal of hypertension

authors： Abrahams Z,Pang MY,Lam EK,Wright JM

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:Recent epidemiological studies have reported inverse associations between vitamin D status and blood pressure. The study aim is to determine if exposure to ultraviolet B radiation, which synthesizes vitamin D, lowers blood pressure, compared with ultraviolet A radiation. METHODS:Men and women (n = 119) with...

journal_title：Journal of hypertension

authors： Scragg R,Wishart J,Stewart A,Ofanoa M,Kerse N,Dyall L,Lawes CM

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To characterize an ATP-sensitive K+ channel at the single-channel and tissue level in the vascular smooth muscle of normotensive and genetically hypertensive rats. METHODS:Age- and sex-matched Wistar-Kyoto (WKY) rats and stroke-prone spontaneously hypertensive rats (SHRSP) were used. Patch-clamp single-chann...

journal_title：Journal of hypertension

authors： Furspan PB,Webb RC

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To determine if the contribution of the sympathetic nervous system to blood pressure could be evidenced by low-frequency oscillations of systolic blood pressure (LF(SBP)), reflecting vascular sympathetic modulation, or by the decrease in blood pressure after autonomic blockade. DESIGN:We studied multiple sys...

journal_title：Journal of hypertension

authors： Diedrich A,Jordan J,Tank J,Shannon JR,Robertson R,Luft FC,Robertson D,Biaggioni I

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:We examined the relationship between brachial-ankle pulse wave velocity and the development of cardiovascular disease in a general Japanese population. METHODS:A total of 2916 community-dwelling Japanese individuals without history of cardiovascular disease aged at least 40 years were followed up for an aver...

journal_title：Journal of hypertension

authors： Ninomiya T,Kojima I,Doi Y,Fukuhara M,Hirakawa Y,Hata J,Kitazono T,Kiyohara Y

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:The current study aimed to investigate the value of the computed tomography-based left-versus-right adrenal gland volume ratio (L/Rv) in screening patients with unilateral primary aldosteronism. METHODS:The current study recruited 114 patients who underwent successful adrenal venous sampling (AVS) and adren...

journal_title：Journal of hypertension

authors： Li S,Sun H,Ma L,Zhu Y,Xie W,Sun J,Zhao L,Qing B,Ren Y,Tian H,Chen T

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To compare the prediction of mortality by ambulatory blood pressure monitoring and screening blood pressure measurements in a general population. DESIGN:A prospective cohort study. PATIENTS AND METHODS:We obtained blood pressure data for 1542 subjects (565 men and 977 women) aged > or = 40 years who were fo...

journal_title：Journal of hypertension

authors： Ohkubo T,Imai Y,Tsuji I,Nagai K,Watanabe N,Minami N,Itoh O,Bando T,Sakuma M,Fukao A,Satoh H,Hisamichi S,Abe K

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Primary hypertension is a hereditary disorder characterized by a complex etiological interplay of multiple genetic and environmental factors, until now defying attempts at identifying pathogenetically important genes. The marriage of classical genetics and molecular techniques is now offering a powerful set ...

journal_title：Journal of hypertension

authors： Lindpaintner K

更新日期：1992-02-01 00:00:00

abstract：:Several myosin isoforms are expressed in smooth muscle, based upon both heavy and light chain polymorphisms. These myosin isoenzymes reveal distinct detachment rate constants, thus regulating the responsiveness of the VSMC contractile apparatus to Ca2+, as well as its energetical and mechanical behavior. ...

journal_title：Journal of hypertension

authors： Morano IL

更新日期：1992-05-01 00:00:00