Abstract:
:The aim of this study was to investigate the effect of dopa and catecholamines on the generation of oxygen active species during oxidation of farmorubicin by "Fenton-like" reagents using chemiluminescent and spectrophotometric techniques. The tested catechols were found to reduce the light emission accompanying oxidation of farmorubicin by Co(II) + H2O2 and Cu(II) + H2O2 mixtures. The quenching effect was followed by their rapid oxidation to aminochromes possessing toxic activities.
journal_name
Biopolymersjournal_title
Biopolymersauthors
Kruk I,Lichszteld K,Aboul-Enein HYdoi
10.1002/bip.10161subject
Has Abstractpub_date
2002-01-01 00:00:00pages
421-7issue
6eissn
0006-3525issn
1097-0282journal_volume
67pub_type
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