Intensive care unit acquired muscle weakness: when should we consider rehabilitation?

abstract：:This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show that high-dose vitamin C can prevent or restore microcirculatory flow impairment by inhibiting activation of...

journal_title：Critical care (London, England)

authors： Oudemans-van Straaten HM,Spoelstra-de Man AM,de Waard MC

更新日期：2014-08-06 00:00:00

abstract：INTRODUCTION:Our aim was to evaluate the role of B-type natriuretic peptide (BNP) percentage variations at 24 hours and at discharge compared to its value at admission in order to demonstrate its predictive value for outcomes in patients with acute decompensated heart failure (ADHF). METHODS:This was a multicenter Ita...

journal_title：Critical care (London, England)

authors： Di Somma S,Magrini L,Pittoni V,Marino R,Mastrantuono A,Ferri E,Ballarino P,Semplicini A,Bertazzoni G,Carpinteri G,Mulè P,Pazzaglia M,Shah K,Maisel A,Clopton P

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Epidemiologic assessment of critically ill people in Intensive Care Units (ICUs) is needed to ensure the health care system can meet current and future needs. However, few such studies have been published. METHODS:Population-based analysis of all adult ICU care in the Canadian province of Manitoba, 1999 t...

journal_title：Critical care (London, England)

authors： Garland A,Olafson K,Ramsey CD,Yogendran M,Fransoo R

更新日期：2013-09-30 00:00:00

abstract：BACKGROUND:Several choices of inotropic therapy are available and used in relation to cardiac surgery. Comparisons are necessary to select optimal therapy. In Denmark, dobutamine and milrinone are the two inotropic agents most commonly used to treat post-bypass low cardiac output syndrome. This study compares all-cause...

journal_title：Critical care (London, England)

authors： Nielsen DV,Torp-Pedersen C,Skals RK,Gerds TA,Karaliunaite Z,Jakobsen CJ

更新日期：2018-02-26 00:00:00

abstract：:Sepsis, despite recent therapeutic progress, still carries unacceptably high mortality rates. The adrenergic system, a key modulator of organ function and cardiovascular homeostasis, could be an interesting new therapeutic target for septic shock. Beta-adrenergic regulation of the immune function in sepsis is complex ...

journal_title：Critical care (London, England)

authors： de Montmollin E,Aboab J,Mansart A,Annane D

更新日期：2009-01-01 00:00:00

abstract：:This commentary on a paper by Bendel and colleagues in the previous issue of Critical Care describes the difficulty in assessing the sufficiency of adrenal responses to endogenous, stress-induced adrenocorticotropic hormone (ACTH) release by the pituitary or to exogenous ACTH administration in the critically ill patie...

journal_title：Critical care (London, England)

authors： Groeneveld AB,Beishuizen A,Molenaar N

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Early identification of predictors for a poor long-term outcome in patients who survive the initial phase of out-of-hospital cardiac arrest (OHCA) may facilitate future clinical research, the process of care and information provided to relatives. The aim of this study was to determine the association between...

journal_title：Critical care (London, England)

authors： Martinell L,Nielsen N,Herlitz J,Karlsson T,Horn J,Wise MP,Undén J,Rylander C

更新日期：2017-04-13 00:00:00

abstract：INTRODUCTION:Sepsis, severe sepsis and septic shock are common conditions with high mortality. Their early diagnosis in the Emergency Department (ED) is one of the keys to improving survival. Procalcitonin (PCT) has been used as a biomarker in septic patients but has limited specificity and can be elevated in other sce...

journal_title：Critical care (London, England)

authors： Ulla M,Pizzolato E,Lucchiari M,Loiacono M,Soardo F,Forno D,Morello F,Lupia E,Moiraghi C,Mengozzi G,Battista S

更新日期：2013-07-30 00:00:00

abstract：:The aim of perioperative haemodilution is to reduce loss of red blood cells during elective surgery. The oncotic and molecular characteristics of the various plasma substitutes employed determine how effectively normovolaemia is maintained, and their non-oncotic effects include alterations in microvascular perfusion. ...

journal_title：Critical care (London, England)

authors： Creagh-Brown BC,Evans TW

更新日期：2008-01-01 00:00:00

abstract：:Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms. This paper gives an overview of the problems related to their current design and the objectives of monitoring. The current approaches used to improve the s...

journal_title：Critical care (London, England)

authors： Chambrin MC

更新日期：2001-08-01 00:00:00

abstract：INTRODUCTION:Timely administration of appropriate antibiotic therapy has been shown to improve outcome in hospital-acquired pneumonia (HAP). Empirical treatment guidelines tailored to local ecology have been advocated in antibiotic stewardship programs. We compared a local ecology based algorithm (LEBA) to a surveillan...

journal_title：Critical care (London, England)

authors： De Bus L,Saerens L,Gadeyne B,Boelens J,Claeys G,De Waele JJ,Benoit DD,Decruyenaere J,Depuydt PO

更新日期：2014-07-15 00:00:00

abstract：INTRODUCTION:Delayed patient admission to the intensive care unit (ICU) due to lack of bed availability is a common problem, but the effect on patient outcome is not fully known. METHODS:A retrospective study was performed using departmental computerised records to determine the effect of delayed ICU admission and tem...

journal_title：Critical care (London, England)

authors： O'Callaghan DJ,Jayia P,Vaughan-Huxley E,Gribbon M,Templeton M,Skipworth JR,Gordon AC

更新日期：2012-10-01 00:00:00

abstract：:BACKGROUND: The present study was undertaken to examine the feasibility of venous oxygen measurements in the inferior vena cava (IVC) via a catheter through the umbilical vein. This may serve as a proxy for mixed venous oxygenation and the complications of right atrial cannulation can be avoided at the same time. It h...

journal_title：Critical care (London, England)

authors： Plötz FB,van Lingen RA,Bos AP

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. As mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (QoL) may occur, not only in t...

journal_title：Critical care (London, England)

authors： Wintermann GB,Petrowski K,Weidner K,Strauß B,Rosendahl J

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with complex, life-threatening diseases. Several factors may influence their performance, including age, tr...

journal_title：Critical care (London, England)

authors： Castro R,Nin N,Ríos F,Alegría L,Estenssoro E,Murias G,Friedman G,Jibaja M,Ospina-Tascon G,Hurtado J,Marín MDC,Machado FR,Cavalcanti AB,Dubin A,Azevedo L,Cecconi M,Bakker J,Hernandez G,Latin-American Intensive Care Net

更新日期：2018-02-21 00:00:00

abstract：BACKGROUND:Accurate prediction of delirium in the intensive care unit (ICU) may facilitate efficient use of early preventive strategies and stratification of ICU patients by delirium risk in clinical research, but the optimal delirium prediction model to use is unclear. We compared the predictive performance and user c...

journal_title：Critical care (London, England)

authors： Wassenaar A,Schoonhoven L,Devlin JW,van Haren FMP,Slooter AJC,Jorens PG,van der Jagt M,Simons KS,Egerod I,Burry LD,Beishuizen A,Matos J,Donders ART,Pickkers P,van den Boogaard M

更新日期：2018-05-05 00:00:00

abstract：:There has been a lot of debate about the concept of relative adrenocortical insufficiency (often defined as a reduced response to corticotropin) as a pathophysiological explanation of steroid effects in septic shock. Less is known about the prevalence of absolute adrenocortical insufficiency based on more usual defini...

journal_title：Critical care (London, England)

authors： Bollaert PE

更新日期：2008-01-01 00:00:00

abstract：:The use of controlled mechanical ventilation (CMV) in patients who experience weaning failure after a spontaneous breathing trial or after extubation is a strategy based on the premise that respiratory muscle fatigue (requiring rest to recover) is the cause of weaning failure. Recent evidence, however, does not suppor...

journal_title：Critical care (London, England)

authors： Vassilakopoulos T,Zakynthinos S,Roussos C

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Identification of bacterial infections is crucial if treatment is to be initiated early and antibiotics used rationally. The primary objective of this study was to test the efficiency of procalcitonin (PCT) in identifying bacterial/parasitic episodes among febrile adult patients presenting to an emergency ...

journal_title：Critical care (London, England)

authors： Hausfater P,Juillien G,Madonna-Py B,Haroche J,Bernard M,Riou B

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The current shortage of accurate and readily available, validated biomarkers of disease severity in sepsis is an important limitation when attempting to stratify patients into homogeneous groups, in order to study pathogenesis or develop therapeutic interventions. The aim of the present study was to determ...

journal_title：Critical care (London, England)

authors： Bozza FA,Salluh JI,Japiassu AM,Soares M,Assis EF,Gomes RN,Bozza MT,Castro-Faria-Neto HC,Bozza PT

更新日期：2007-01-01 00:00:00

abstract：:Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Administration of recombinant human activated protein C (rhAPC) may correct the dysregulated anticoagulant mechanism and prevent propagation of thrombin generation and formation of microvascular thrombosis. Furthermore, it may simu...

journal_title：Critical care (London, England)

authors： Levi M,van der Poll T

更新日期：2007-01-01 00:00:00

abstract：:The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues als...

journal_title：Critical care (London, England)

authors： Ball J,Venn R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) is increasingly used as an indirect measure of ICP, and quantitative EEG (QEEG) can ...

journal_title：Critical care (London, England)

authors： Chen Y,Xu W,Wang L,Yin X,Cao J,Deng F,Xing Y,Feng J

更新日期：2018-02-20 00:00:00

abstract：:Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

journal_title：Critical care (London, England)

authors： Tomlinson LA,Forni LG

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Uncalibrated arterial pulse power analysis has been recently introduced for continuous monitoring of cardiac index (CI). The aim of the present study was to compare the accuracy of arterial pulse power analysis with intermittent transpulmonary thermodilution (TPTD) before and after cardiopulmonary bypass (...

journal_title：Critical care (London, England)

authors： Broch O,Renner J,Höcker J,Gruenewald M,Meybohm P,Schöttler J,Steinfath M,Bein B

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Survival after cadaveric lung transplantation (LTx) in respiratory failure recipients who were already dependent on ventilation support prior to transplantation is poor, with a relatively high rate of surgical mortality and morbidity. In this study, we sought to describe the short-term outcomes of bilatera...

journal_title：Critical care (London, England)

authors： Hsu HH,Chen JS,Ko WJ,Huang SC,Kuo SW,Huang PM,Chi NH,Chang CC,Chen RJ,Lee YC

更新日期：2009-01-01 00:00:00

abstract：:Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income countries. Barriers to reducing the global burden of sepsis include difficulty quantifying attributable morbidity and mortality, low awareness, poverty and health inequ...

journal_title：Critical care (London, England)

authors： Rudd KE,Kissoon N,Limmathurotsakul D,Bory S,Mutahunga B,Seymour CW,Angus DC,West TE

更新日期：2018-09-23 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Patients admitted to intensive care following surgery for faecal peritonitis present particular challenges in terms of clinical management and risk assessment. Collaborating surgical and intensive care teams need shared perspectives on prognosis. We aimed to determine the relationship between dynamic asses...

journal_title：Critical care (London, England)

authors： Tridente A,Clarke GM,Walden A,Gordon AC,Hutton P,Chiche JD,Holloway PA,Mills GH,Bion J,Stüber F,Garrard C,Hinds C,GenOSept Investigators.

更新日期：2015-05-05 00:00:00

abstract：INTRODUCTION:The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, it plays pivotal roles in the pathogenesis of sepsis in several ways. Our previous study showed that rs1800625 (-429T/C) revealed a strong clinical relevance with sepsis morbidity rate and...

journal_title：Critical care (London, England)

authors： Zeng L,Du J,Gu W,Zhang AQ,Wang HY,Wen DL,Qiu L,Yang XT,Sun JH,Zhang M,Hao J,Jiang JX

更新日期：2015-01-09 00:00:00