Rs1800625 in the receptor for advanced glycation end products gene predisposes to sepsis and multiple organ dysfunction syndrome in patients with major trauma.

abstract：INTRODUCTION:Despite recent modifications, the clinical definition of the acute respiratory distress syndrome (ARDS) remains non-specific, leading to under-diagnosis and under-treatment. This study was designed to test the hypothesis that a biomarker panel would be useful for biologic confirmation of the clinical diagn...

journal_title：Critical care (London, England)

authors： Ware LB,Koyama T,Zhao Z,Janz DR,Wickersham N,Bernard GR,May AK,Calfee CS,Matthay MA

更新日期：2013-10-24 00:00:00

abstract：:Tight glycemic control has engendered large numbers of investigations, with conflicting results. The world has largely embraced intensive insulin as a practice, but applies this therapy with great variability in the manner of glucose control and measurement. The present commentary reviews what we actually know with ce...

journal_title：Critical care (London, England)

authors： Nasraway SA Jr,Rattan R

更新日期：2010-01-01 00:00:00

abstract：:Progress in management of critically ill neurological patients has led to improved survival rates. However, severe residual neurological impairment, such as persistent coma, occurs in some survivors. This raises concerns about whether it is ethically appropriate to apply aggressive care routinely, which is also associ...

journal_title：Critical care (London, England)

authors： Weiss N,Galanaud D,Carpentier A,Naccache L,Puybasset L

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:It has been unclear if mechanical cardiopulmonary resuscitation (CPR) is a viable alternative to manual CPR. We aimed to compare resuscitation outcomes before and after switching from manual CPR to load-distributing band (LDB) CPR in a multi-center emergency department (ED) trial. METHODS:We conducted a p...

journal_title：Critical care (London, England)

authors： Hock Ong ME,Fook-Chong S,Annathurai A,Ang SH,Tiah L,Yong KL,Koh ZX,Yap S,Sultana P

更新日期：2012-08-03 00:00:00

abstract：INTRODUCTION:Sepsis-related multiple organ dysfunction is a common cause of death in the intensive care unit. The effect of sepsis on markers of tissue repair is only partly understood. The aim of this study was to measure markers of collagen synthesis and degradation during sepsis and investigate the association with ...

journal_title：Critical care (London, England)

authors： Gäddnäs F,Koskela M,Koivukangas V,Risteli J,Oikarinen A,Laurila J,Saarnio J,Ala-Kokko T

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The choice of invasive systemic haemodynamic monitoring in critically ill patients remains controversial as no multicentre comparative clinical data exist. Accordingly, we sought to study and compare the features and outcomes of patients who receive haemodynamic monitoring with either the pulmonary artery ...

journal_title：Critical care (London, England)

authors： Uchino S,Bellomo R,Morimatsu H,Sugihara M,French C,Stephens D,Wendon J,Honore P,Mulder J,Turner A,PAC\/PiCCO Use and Likelihood of Success Evaluation PULSE Study Group.

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:During septic shock, resistance to the haemodynamic effects of catecholamine vasopressors and inotropes is a well-recognised marker of mortality risk. However, the specific cardiovascular or metabolic response elements that are most closely associated with outcome have not been well defined. The objective ...

journal_title：Critical care (London, England)

authors： Kumar A,Schupp E,Bunnell E,Ali A,Milcarek B,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：:Mechanically ventilated, intubated patients are at increased risk for tracheal colonization with bacterial pathogens that may progress to heavy bacterial colonization, ventilator-associated tracheobronchitis (VAT), and/or ventilator-associated pneumonia (VAP). Previous studies report that 10 to 30 % of patients with V...

journal_title：Critical care (London, England)

authors： Craven DE,Hudcova J,Lei Y,Craven KA,Waqas A

更新日期：2016-09-29 00:00:00

abstract：INTRODUCTION:Pulmonary embolism (PE) is one of the greatest diagnostic challenges in prehospital emergency setting. Most patients with suspected PE have a positive D-dimer and undergo diagnostic testing. Excluding PE with additional non-invasive tests would reduce the need for further imaging tests. We aimed to determi...

journal_title：Critical care (London, England)

authors： Rumpf TH,Krizmaric M,Grmec S

更新日期：2009-01-01 00:00:00

abstract：:An influenza pandemic threatens to be the most lethal public health crisis to confront the world. Physicians will have critical roles in diagnosis, containment and treatment of influenza, and their commitment to treat despite increased personal risks is essential for a successful public health response. The obligation...

journal_title：Critical care (London, England)

authors： Anantham D,McHugh W,O'Neill S,Forrow L

更新日期：2008-01-01 00:00:00

abstract：:Percutaneous dilatation tracheostomy in the intensive care setting presents an increasingly important concept for establishing a large-bore tracheal airway with minimal surgical intervention. Over the last years, different technical solutions have been studied to assess their respective risks and benefits to determine...

journal_title：Critical care (London, England)

authors： Brambrink A

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Tight glucose control therapy (TGC) has been implemented to control hyperglycemia in ICU patients. TGC may also influence serum potassium concentrations. We therefore investigated the influence of TGC on both serum glucose and serum potassium concentrations and associated mortality. METHOD:We performed a ...

journal_title：Critical care (London, England)

authors： Uijtendaal EV,Zwart-van Rijkom JE,de Lange DW,Lalmohamed A,van Solinge WW,Egberts TC

更新日期：2015-06-22 00:00:00

abstract：:In the publication of this article [1], there are 4 collaborating authors missing from the 'MARS consortium'. This has now been included in this correction article. ...

journal_title：Critical care (London, England)

authors： Klein Klouwenberg PMC,Spitoni C,van der Poll T,Bonten MJ,Cremer OL,MARS consortium.

更新日期：2020-02-06 00:00:00

abstract：INTRODUCTION:Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resis...

journal_title：Critical care (London, England)

authors： Nielsen ST,Janum S,Krogh-Madsen R,Solomon TP,Møller K

更新日期：2015-11-16 00:00:00

abstract：INTRODUCTION:Expanding the criteria for deceased organ donors increases the risk of delayed graft function (DGF) and complicates kidney transplant outcome. We studied whether donor neutrophil gelatinase-associated lipocalin (NGAL), a novel biomarker for acute kidney injury, could predict DGF after transplantation. MET...

journal_title：Critical care (London, England)

authors： Hollmen ME,Kyllönen LE,Inkinen KA,Lalla ML,Merenmies J,Salmela KT

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:In critically ill patients, delirium is a serious and frequent disorder that is associated with a prolonged intensive care and hospital stay and an increased morbidity and mortality. Without the use of a delirium screening instrument, delirium is often missed by ICU nurses and physicians. The effects of im...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Pickkers P,van der Hoeven H,Roodbol G,van Achterberg T,Schoonhoven L

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:This study aimed to examine the long-term outcome for patients with end-stage renal failure (ESRF) who survived multiple-organ failure. METHODS:We performed a review of databases from the renal medicine service and intensive care units (ICU) of the participating hospitals within Imperial College Healthcar...

journal_title：Critical care (London, England)

authors： Chapman RJ,Templeton M,Ashworth S,Broomhead R,McLean A,Brett SJ

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Pulse-pressure variation (PPV) due to increased right ventricular afterload and dysfunction may misleadingly suggest volume responsiveness. We aimed to assess prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure. METHODS:Fifteen cardiac surgery patients with a ...

journal_title：Critical care (London, England)

authors： Wyler von Ballmoos M,Takala J,Roeck M,Porta F,Tueller D,Ganter CC,Schröder R,Bracht H,Baenziger B,Jakob SM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Little is known about the development of acute lung injury outside the intensive care unit. We set out to document the following: the association between predefined clinical conditions and the development of acute lung injury by using the American-European consensus definition; the frequency of lung injury d...

journal_title：Critical care (London, England)

authors： Ferguson ND,Frutos-Vivar F,Esteban A,Gordo F,Honrubia T,Peñuelas O,Algora A,García G,Bustos A,Rodríguez I

更新日期：2007-01-01 00:00:00

abstract：:The multicenter study conducted by Lorente and coworkers published in the previous issue of Critical Care demonstrates that matrix metalloproteinase (MMP)-9 and MMP-10 and their inhibitor tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) are promising novel biomarkers to predict severity and outcome of sepsis. I...

journal_title：Critical care (London, England)

authors： Hoffmann U,Brueckmann M,Borggrefe M

更新日期：2009-01-01 00:00:00

abstract：:Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...

journal_title：Critical care (London, England)

authors： Schneider AG,Journois D,Rimmelé T

更新日期：2017-11-19 00:00:00

abstract：INTRODUCTION:The effect of sepsis on epidermal wound healing has not been previously studied. It was hypothesised that epidermal wound healing is disturbed in severe sepsis. METHODS:Blister wounds were induced in 35 patients with severe sepsis and in 15 healthy controls. The healing of the wounds was followed up by me...

journal_title：Critical care (London, England)

authors： Koskela M,Gäddnäs F,Ala-Kokko TI,Laurila JJ,Saarnio J,Oikarinen A,Koivukangas V

更新日期：2009-01-01 00:00:00

abstract：:Considerable progress has been made recently in the understanding of how best to accomplish safe and effective ventilation of patients with acute lung injury. Mechanical and nonmechanical factors contribute to causation of ventilator-associated lung injury. Intervention timing helps determine the therapeutic efficacy ...

journal_title：Critical care (London, England)

authors： Marini JJ

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:In severely neutropenic septic acute respiratory distress syndrome (ARDS) patients, macrophages and monocytes are the last potentially remaining innate immune cells. We have previously shown, however, a deactivation of the alveolar macrophage in neutropenic septic ARDS patients. In the present study, we tr...

journal_title：Critical care (London, England)

authors： Mokart D,Kipnis E,Guerre-Berthelot P,Vey N,Capo C,Sannini A,Brun JP,Blache JL,Mege JL,Blaise D,Guery BP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Providing supplemental amino acids to ICU patients during a 3-h period results in improved whole-body net protein balance, without an increase in amino acid oxidation. The primary objective was to investigate if a 24-h intravenous amino acid infusion in critically ill patients has a sustained effect on whole...

journal_title：Critical care (London, England)

authors： Sundström Rehal M,Liebau F,Tjäder I,Norberg Å,Rooyackers O,Wernerman J

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow ...

journal_title：Critical care (London, England)

authors： Akin S,Dos Reis Miranda D,Caliskan K,Soliman OI,Guven G,Struijs A,van Thiel RJ,Jewbali LS,Lima A,Gommers D,Zijlstra F,Ince C

更新日期：2017-10-26 00:00:00

abstract：BACKGROUND:There are no easily available markers of renal recovery to guide intermittent hemodialysis (IHD) weaning. The aim of this study was to identify markers for IHD weaning in critically ill patients with acute kidney injury (AKI). METHODS:We performed a retrospective single-center cohort study of patients treat...

journal_title：Critical care (London, England)

authors： Aniort J,Ait Hssain A,Pereira B,Coupez E,Pioche PA,Leroy C,Heng AE,Souweine B,Lautrette A

更新日期：2016-02-19 00:00:00

abstract：:During the past 50 years, caring for the critically ill has become increasingly complex and the need for an intensivist has become more evident. Management by intensivists has become a quality indicator for many ICUs. Numerous small studies have demonstrated the beneficial effect of intensivists on outcomes in the cri...

journal_title：Critical care (London, England)

authors： Levy MM

更新日期：2013-10-14 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Martin CM

更新日期：2018-11-03 00:00:00

abstract：:The pulmonary artery catheter (PAC) was introduced in 1971 for the assessment of heart function at the bedside. Since then it has generated much enthusiasm and controversy regarding the benefits and potential harms caused by this invasive form of hemodynamic monitoring. This review discusses all clinical studies condu...

journal_title：Critical care (London, England)

authors： Hadian M,Pinsky MR

更新日期：2006-01-01 00:00:00