The 21st International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 20-23 March 2001.


:The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues also received attention. Overall, the 'state of the art' lectures, pro/con debates, seminars and tutorials were of a high standard. The meeting was marked by a sense of renewed enthusiasm that positive progress is occurring in intensive care medicine.


Crit Care


Ball J,Venn R





Has Abstract


2001-01-01 00:00:00












  • Uneven distribution of ventilation in acute respiratory distress syndrome.

    abstract:INTRODUCTION:The aim of this study was to assess the volume of gas being poorly ventilated or non-ventilated within the lungs of patients treated with mechanical ventilation and suffering from acute respiratory distress syndrome (ARDS). METHODS:A prospective, descriptive study was performed of 25 sedated and paralysed...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Rylander C,Tylén U,Rossi-Norrlund R,Herrmann P,Quintel M,Bake B

    更新日期:2005-04-01 00:00:00

  • A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes.

    abstract:INTRODUCTION:Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not all severely ill develop hyperglycemia and some do even in mild disease. We hypothesised that acute disease only ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Gornik I,Vujaklija-Brajkovic A,Renar IP,Gasparovic V

    更新日期:2010-01-01 00:00:00

  • Burn wound healing and treatment: review and advancements.

    abstract::Burns are a prevalent and burdensome critical care problem. The priorities of specialized facilities focus on stabilizing the patient, preventing infection, and optimizing functional recovery. Research on burns has generated sustained interest over the past few decades, and several important advancements have resulted...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Rowan MP,Cancio LC,Elster EA,Burmeister DM,Rose LF,Natesan S,Chan RK,Christy RJ,Chung KK

    更新日期:2015-06-12 00:00:00

  • Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury.

    abstract:BACKGROUND:Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). However, evidence regarding the prognostic effect of the platelet-to-lymphocyte ratio (PLR), a novel systemic inflammation marker, among patients with AKI is scarce. In this study, we investigated the value o...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Zheng CF,Liu WY,Zeng FF,Zheng MH,Shi HY,Zhou Y,Pan JY

    更新日期:2017-09-08 00:00:00

  • Prediction of fluid challenge effect: filling pressure when left ventricular function is abnormal, diastolic volume when left ventricular function is normal.

    abstract::Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive t...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Payen D

    更新日期:2011-01-01 00:00:00

  • Central venous pressure measurement is associated with improved outcomes in septic patients: an analysis of the MIMIC-III database.

    abstract:PURPOSE:Measurement of central venous pressure (CVP) can be a useful clinical tool. However, the formal utility of CVP measurement in preventing mortality in septic patients has never been proven. METHODS:The Medical Information Mart for Intensive Care III (MIMIC-III) database was searched to identify septic patients ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Chen H,Zhu Z,Zhao C,Guo Y,Chen D,Wei Y,Jin J

    更新日期:2020-07-14 00:00:00

  • Semi-elemental versus polymeric formula for enteral nutrition in brain-injured critically ill patients: a randomized trial.

    abstract:BACKGROUND:The properties of semi-elemental enteral nutrition might theoretically improve gastrointestinal tolerance in brain-injured patients, known to suffer gastroparesis. The purpose of this study was to compare the efficacy and tolerance of a semi-elemental versus a polymeric formula for enteral nutrition (EN) in ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Carteron L,Samain E,Winiszewski H,Blasco G,Balon AS,Gilli C,Piton G,Capellier G,Pili-Floury S,Besch G

    更新日期:2021-01-20 00:00:00

  • Decreased CX3CR1 messenger RNA expression is an independent molecular biomarker of early and late mortality in critically ill patients.

    abstract:BACKGROUND:Chemokine (C-X3-C motif) receptor 1 (CX3CR1) was identified as the most differentially expressed gene between survivors and non-survivors in two independent cohorts of septic shock patients and was proposed as a marker of sepsis-induced immunosuppression. Whether such a biomarker is associated with mortality...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Friggeri A,Cazalis MA,Pachot A,Cour M,Argaud L,Allaouchiche B,Floccard B,Schmitt Z,Martin O,Rimmelé T,Fontaine-Kesteloot O,Page M,Piriou V,Bohé J,Monneret G,Morisset S,Textoris J,Vallin H,Blein S,Maucort-Boulch D,

    更新日期:2016-06-30 00:00:00

  • Inter-hospital transport of critically ill patients; expect surprises.

    abstract:INTRODUCTION:Inter-hospital transport of critically ill patients is increasing. When performed by specialized retrieval teams there are less adverse events compared to transport by ambulance. These transports are performed with technical equipment also used in an Intensive Care Unit (ICU). As a consequence technical pr...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Droogh JM,Smit M,Hut J,de Vos R,Ligtenberg JJ,Zijlstra JG

    更新日期:2012-02-12 00:00:00

  • Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction.

    abstract:INTRODUCTION:Multiple organ dysfunction syndrome (MODS) is a common complication of sepsis in mechanically ventilated patients with acute respiratory distress syndrome, but the links between mechanical ventilation and MODS are unclear. Our goal was to determine whether a minimally injurious mechanical ventilation strat...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: O'Mahony DS,Liles WC,Altemeier WA,Dhanireddy S,Frevert CW,Liggitt D,Martin TR,Matute-Bello G

    更新日期:2006-01-01 00:00:00

  • Case mix, outcome, and activity for admissions to UK critical care units with severe acute pancreatitis: a secondary analysis of the ICNARC Case Mix Programme Database.

    abstract:INTRODUCTION:Severe acute pancreatitis (SAP) requiring admission to a critical care unit is associated with high mortality and long lengths of stay. We describe the case mix, outcome, and activity of admissions with SAP who were identified from a high-quality clinical database. METHODS:We conducted a secondary analysi...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Harrison DA,D'Amico G,Singer M

    更新日期:2007-01-01 00:00:00

  • Bench-to-bedside review: Chloride in critical illness.

    abstract::Chloride is the principal anion in the extracellular fluid and is the second main contributor to plasma tonicity. Its concentration is frequently abnormal in intensive care unit patients, often as a consequence of fluid therapy. Yet chloride has received less attention than any other ion in the critical care literatur...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Yunos NM,Bellomo R,Story D,Kellum J

    更新日期:2010-01-01 00:00:00

  • Tracheal extubation and reintubation of the critically ill--challenges coming and going.

    abstract::Tracheal reintubation is a common event in critical care. Elmer and colleagues provide the first comparison of complication rates of initial and subsequent reintubation(s) during the same hospitalization. Their work shows an increased risk of complications associated with reintubation, in particular hypoxemia and hypo...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Parotto M,Cooper RM

    更新日期:2015-03-27 00:00:00

  • Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial.

    abstract:INTRODUCTION:Although early use of broad-spectrum antimicrobials in critically ill patients may increase antimicrobial adequacy, uncontrolled use of these agents may select for more-resistant organisms. This study investigated the effects of early use of broad-spectrum antimicrobials in critically ill patients with hos...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Kim JW,Chung J,Choi SH,Jang HJ,Hong SB,Lim CM,Koh Y

    更新日期:2012-02-15 00:00:00

  • Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study.

    abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-day survival probability among adult hospitalized patients with COVID-19. METHODS:In this multicent...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Zhang S,Guo M,Duan L,Wu F,Hu G,Wang Z,Huang Q,Liao T,Xu J,Ma Y,Lv Z,Xiao W,Zhao Z,Tan X,Meng D,Zhang S,Zhou E,Yin Z,Geng W,Wang X,Zhang J,Chen J,Zhang Y,Jin Y

    更新日期:2020-07-16 00:00:00

  • Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent?

    abstract::Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, i...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Berger D,Takala J

    更新日期:2016-06-09 00:00:00

  • Serum procalcitonin measurement as diagnostic and prognostic marker in febrile adult patients presenting to the emergency department.

    abstract:INTRODUCTION:Identification of bacterial infections is crucial if treatment is to be initiated early and antibiotics used rationally. The primary objective of this study was to test the efficiency of procalcitonin (PCT) in identifying bacterial/parasitic episodes among febrile adult patients presenting to an emergency ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Hausfater P,Juillien G,Madonna-Py B,Haroche J,Bernard M,Riou B

    更新日期:2007-01-01 00:00:00

  • Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis.

    abstract:BACKGROUND:The intestinal microbiota plays a crucial role in human health, which could affect host immunity and the susceptibility to infectious diseases. However, the role of intestinal microbiota in the immunopathology of invasive candidiasis remains unknown. METHODS:In this work, an antibiotic cocktail was used to ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Li M,Li C,Wu X,Chen T,Ren L,Xu B,Cao J

    更新日期:2020-05-27 00:00:00

  • Pro/con clinical debate: steroids are a key component in the treatment of SARS. Pro: Yes, steroids are a key component of the treatment regimen for SARS.

    abstract::SARS (severe acute respiratory syndrome) proved an enormous physical and emotional challenge to frontline health care workers throughout the world in late 2002 through to mid 2003. A large percentage of patients (many being health care workers themselves) became critically ill. Unfortunately, clinicians caring for the...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Gomersall CD

    更新日期:2004-04-01 00:00:00

  • Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury.

    abstract:INTRODUCTION:Sepsis is the leading cause of acute kidney injury (AKI) in critical patients. The optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains controversial. The objective of this study is to determine the impact of early or late initiation of RRT, as defined using the simpl...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Chou YH,Huang TM,Wu VC,Wang CY,Shiao CC,Lai CF,Tsai HB,Chao CT,Young GH,Wang WJ,Kao TW,Lin SL,Han YY,Chou A,Lin TH,Yang YW,Chen YM,Tsai PR,Lin YF,Huang JW,Chiang WC,Chou NK,Ko WJ,Wu KD,Tsai TJ,NSARF Stud

    更新日期:2011-01-01 00:00:00

  • Ventilator-induced lung injury and mechanotransduction: why should we care?

    abstract::Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to bas...

    journal_title:Critical care (London, England)

    pub_type: 评论,社论


    authors: Liu M

    更新日期:2007-01-01 00:00:00

  • Complications of regional citrate anticoagulation: accumulation or overload?

    abstract::Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Schneider AG,Journois D,Rimmelé T

    更新日期:2017-11-19 00:00:00

  • The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic review.

    abstract:BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality; therefore, the early diagnosis of neonatal sepsis is essential. METHOD:Our aim was to compare the diagnostic accuracy of procalcitonin (PCT), C-reactive protein (CRP), procalcitonin combined with C-reactive protein (PCT + CRP) and presepsin i...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析


    authors: Ruan L,Chen GY,Liu Z,Zhao Y,Xu GY,Li SF,Li CN,Chen LS,Tao Z

    更新日期:2018-11-21 00:00:00

  • Prehospital point of care testing of blood gases and electrolytes - an evaluation of IRMA.

    abstract::BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Prause G,Ratzenhofer-Komenda B,Offner A,Lauda P,Voit H,Pojer H

    更新日期:1997-01-01 00:00:00

  • Early vs late start of dialysis: it's all about timing.

    abstract::Acute kidney injury (AKI) is now well recognized as an independent risk factor for increased morbidity and mortality, particularly when dialysis is needed. The wide variation in dialysis utilization contributes to a lack of consensus on what parameters should guide the decision to start dialysis. While the association...

    journal_title:Critical care (London, England)

    pub_type: 评论,信件


    authors: Macedo E,Mehta RL

    更新日期:2010-01-01 00:00:00

  • Fluid-limiting treatment strategies among sepsis patients in the ICU: a retrospective causal analysis.

    abstract:OBJECTIVE:In septic patients, multiple retrospective studies show an association between large volumes of fluids administered in the first 24 h and mortality, suggesting a benefit to fluid restrictive strategies. However, these studies do not directly estimate the causal effects of fluid-restrictive strategies, nor do ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Shahn Z,Shapiro NI,Tyler PD,Talmor D,Lehman LH

    更新日期:2020-02-22 00:00:00

  • Risk management in patients with severe acute pancreatitis.

    abstract::Primary or secondary infection of necrotized areas by enteral bacteria is considered a primary cause of mortality in patients with severe acute pancreatitis (SAP). Indeed, 20-30% of patients die during the course of the disease from multiple organ dysfunction after infection. This is why strategies such as antibiotic ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Gerlach H

    更新日期:2004-12-01 00:00:00

  • Year in review 2013: Critical Care--sepsis.

    abstract::This review presents key publications from the research field of sepsis published in Critical Care and other relevant journals during 2013. The results of these experimental studies and clinical trials are discussed in the context of current scientific and clinical background. The discussion highlights and summarises ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: de Montmollin E,Annane D

    更新日期:2014-10-15 00:00:00

  • Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial.

    abstract:BACKGROUND:Simvastatin therapy for patients with acute respiratory distress syndrome (ARDS) has been shown to be safe and associated with minimal adverse effects, but it does not improve clinical outcomes. The aim of this research was to report on mortality and cost-effectiveness of simvastatin in patients with ARDS at...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Agus A,Hulme C,Verghis RM,McDowell C,Jackson C,O'Kane CM,Laffey JG,McAuley DF

    更新日期:2017-05-17 00:00:00

  • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial.

    abstract:BACKGROUND:Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from traffic or sporting accidents. Although there are a number of animal models of TBI using progesterone for head injury, the effects of progesterone on neurologic outcome of acute TBI patients remain unclear. The ai...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Xiao G,Wei J,Yan W,Wang W,Lu Z

    更新日期:2008-01-01 00:00:00