Stress hormones enhance retrieval of fear conditioning acquired either one day or many months before.

abstract：:In a modified light-dark exploration test in mice, 5-hydroxytryptophan, at doses (25-50 mg/kg) that approximately doubled the 5-HT content in the cerebral cortex, reduced the time spent by mice in the white compartment, suggesting an anxiogenic effect. Depletion of brain 5-HT content with p-chlorophenylalanine (300 mg...

journal_title：Behavioural pharmacology

authors： Artaiz I,Zazpe A,Del Río J

更新日期：1998-03-01 00:00:00

abstract：:In light of the adverse side-effects of opioids, cannabinoid receptor agonists may provide an effective alternative for the treatment of cancer pain. This study examined the potency and efficacy of synthetic CB1 and CB2 receptor agonists in a murine model of tumor pain. Intraplantar injection of the CB1 receptor agoni...

journal_title：Behavioural pharmacology

authors： Khasabova IA,Gielissen J,Chandiramani A,Harding-Rose C,Odeh DA,Simone DA,Seybold VS

更新日期：2011-09-01 00:00:00

abstract：:Central nicotinc acetylcholine receptors have been targeted for the development of novel treatments for memory deficits in Alzheimer's disease (AD) and other neurodegenerative disorders. Nicotine itself has been shown to improve memory-related task performance in aged animals and in AD patients. Administration of nico...

journal_title：Behavioural pharmacology

authors： Buccafusco JJ,Jackson WJ,Jonnala RR,Terry AV Jr

更新日期：1999-11-01 00:00:00

abstract：:'Active immobility' (AI) is an independent behaviour that can be characterized by behavioural immobility, an increased muscular rigidity and the sustaining of an unusual posture. In previous studies with cocaine we observed, concomitant with hyperlocomotion and increased rearing activity, an increase in AI in well-hab...

journal_title：Behavioural pharmacology

authors： Müller CP,Thönnessen H,Jocham G,Barros M,Tomaz C,Carey RJ,Huston JP

更新日期：2004-11-01 00:00:00

abstract：:There is a considerable degree of individual vulnerability for alcohol use disorder (AUD) as only a subpopulation of individuals who regularly consume alcohol develop AUD. It is therefore very important to understand the factors and mechanisms that contribute towards the individual risk for AUD. In this respect, socia...

journal_title：Behavioural pharmacology

authors： Lesscher HM,Spoelder M,Rotte MD,Janssen MJ,Hesseling P,Lozeman-van't Klooster JG,Baars AM,Vanderschuren LJ

更新日期：2015-10-01 00:00:00

abstract：:Recent examination of the mixed dopamine agonist apomorphine suggests that dopamine inhibits both passive avoidance and response suppression learning. The present study investigated the effects of selective dopamine agonists on memory consolidation using a passive avoidance task in the day-old chick. The dopamine D1 a...

journal_title：Behavioural pharmacology

authors： Hale MW,Crowe SF

更新日期：2002-07-01 00:00:00

abstract：:Methoxetamine (MXE) is a chemical analogue of ketamine. Originally proposed as a ketamine-like fast-acting antidepressant, owing to similar N-methyl-D-aspartate blocker properties, it is now scheduled for reports of hallucinations and psychosis similar to ketamine and lysergic acid. As little is known about the addict...

journal_title：Behavioural pharmacology

authors： Chiamulera C,Armani F,Mutti A,Fattore L

更新日期：2016-04-01 00:00:00

abstract：:The interactions of -adrenoceptors and acute restraint stress with morphine state-dependent memory of passive avoidance were examined in mice. Memory acquired following pre-training morphine administration (5 mg/kg, i.p.) was dose- and time-dependently retrieved by pre-test morphine; this effect was reversible by yohi...

journal_title：Behavioural pharmacology

authors： Homayoun H,Khavandgar S,Zarrindast MR

更新日期：2003-02-01 00:00:00

abstract：:The cannabinoid receptor agonist Δ(9)-tetrahydrocannabinol (THC) enhances the antinociceptive effects of µ-opioid receptor agonists, raising the possibility of using a combination of THC and opioids for treating pain. This study examined the effects of noncontingent and contingent administration of THC on intravenous ...

journal_title：Behavioural pharmacology

authors： Li JX,Koek W,France CP

更新日期：2012-12-01 00:00:00

abstract：:The effects of topiramate, a potential treatment for drug dependence, were evaluated in two groups of rats trained to discriminate the administration of either 0.4 mg/kg nicotine or 10 mg/kg cocaine from that of saline, under a fixed-ratio 10 schedule of food delivery. Topiramate (1-60 mg/kg, intraperitoneal) did not ...

journal_title：Behavioural pharmacology

authors： Le Foll B,Justinova Z,Wertheim CE,Barnes C,Goldberg SR

更新日期：2008-02-01 00:00:00

abstract：:This study was designed to explore whether differences in the psychomotor, subjective and memory effects of different benzodiazepines (BDZ) relate to differences in their potencies. Two BDZs with similar kinetics but different potencies were compared. Flunitrazepam (0.5 and 1.0mg, nitrazepam (5 and 10mg) or placebo we...

journal_title：Behavioural pharmacology

authors： Pompéia S,Gorenstein C,Curran HV

更新日期：1996-11-01 00:00:00

abstract：:Obesity and cigarette smoking are often cited separately as the top two preventable causes of death in the United States; however, little research has explored the factors associated with being both obese and a smoker. Delay discounting is a behavioral characteristic that may underlie both of these conditions/behavior...

journal_title：Behavioural pharmacology

authors： Fields SA,Sabet M,Peal A,Reynolds B

更新日期：2011-06-01 00:00:00

abstract：:Environmental and situational factors are important determinants of recreational drug use in humans. We aimed to develop a reliable animal model for studying the effects of environmental variables on drug-seeking behavior using the 'social isolation/social restriction' paradigm. Adult Wistar rats housed in short-term ...

journal_title：Behavioural pharmacology

authors： Raz S,Berger BD

更新日期：2010-02-01 00:00:00

abstract：:Nitrous oxide (N2O) effects were evaluated, as a behavioural model of inert gas narcosis, in rats performing a vigilance task in which they were required to respond to a slight luminous increment of the house-light. A dose-related decrease of correct responses was produced by the tested range of concentrations of N2O ...

journal_title：Behavioural pharmacology

authors： Courtière A,Hardouin J

更新日期：1997-10-01 00:00:00

abstract：:Male Syrian hamsters (Mesocricetus auratus) treated with anabolic/androgenic steroids (AAS) during adolescence (P27-P56) display highly escalated and mature forms of offensive aggression correlated with increased γ-aminobutyric acid (GABA) afferent development as well as decreased GABAA receptors in the lateroanterior...

journal_title：Behavioural pharmacology

authors： Morrison TR,Ricci LA,Melloni RH Jr

更新日期：2014-10-01 00:00:00

abstract：:Appetitive behaviours occur in a state of behavioural and physiological activation that allows the optimal performance of these goal-directed behaviours. Here, we tested the hypothesis that histamine neurons under the command of the infralimbic cortex are important to provide behavioural activation. Extracellular hist...

journal_title：Behavioural pharmacology

authors： Riveros ME,Forray MI,Torrealba F

更新日期：2015-06-01 00:00:00

abstract：:The psychomotor/cognitive performance, subject-rated, and observer-rated effects of single oral doses of the benzodiazepine hypnotic triazolam (0.125, 0.25, and 0.5 mg/70 kg) and the imidazopyridine hypnotic zolpidem (5, 10, and 20 mg/70 kg) were compared in 11 volunteers, in a double-blind, placebo-controlled, crosso...

journal_title：Behavioural pharmacology

authors： Mintzer MZ,Frey JM,Yingling JE,Griffiths RR

更新日期：1997-11-01 00:00:00

abstract：:Separate groups of rats were trained to discriminate either 0.1mg/kg (low dose; L) or 2.5mg/kg (high dose; H) of 8-OH-DPAT from saline, in a standard operant task. Both cues were found to be dose, time and route dependent and generalized completely to the 5-HT(1A) agonists ipsapirone and flesinoxan. Buspirone substitu...

journal_title：Behavioural pharmacology

authors： Ybema CE,Slangen JL,Olivier B,Mos J

更新日期：1993-12-01 00:00:00

abstract：:The transient receptor potential (TRP) channel superfamily is comprised of a large group of cation-permeable channels, which display an extraordinary diversity of roles in sensory signaling and are involved in plethora of animal behaviors. These channels are activated through a wide variety of mechanisms and participa...

journal_title：Behavioural pharmacology

authors： Tsagareli MG,Nozadze I

更新日期：2020-08-01 00:00:00

abstract：:Effects of the dopamine D(1) antagonist SCH 39166 were compared with those of the D(2) antagonist eticlopride in squirrel monkeys responding under a second-order fixed-interval schedule of i.v. self-administration of cocaine. Dose-response curves were determined for a range of doses of self-administered cocaine (0.01-...

journal_title：Behavioural pharmacology

authors： Bergman J,Kamien JB,Spealman RD

更新日期：1990-01-01 00:00:00

abstract：:Three experiments examined the effects of chronic pre-exposure to caffeine on the subsequent conditioned and unconditioned locomotor activating effects of nicotine or amphetamine in rats. Rats were given daily intraperitoneal injections of caffeine anhydrous (0, 10 or 30 mg/kg base) for 30 days. Conditioning (environm...

journal_title：Behavioural pharmacology

authors： Palmatier MI,Fung EY,Bevins RA

更新日期：2003-05-01 00:00:00

abstract：:The present study used the microdialysis technique to investigate the effect of treadmill running, without the use of an electric grid, on extracellular serotonin in the ventral hippocampus of male Lister hooded rat. Extracellular hippocampal serotonin was measured during 60min of treadmill running at 20m/min and comp...

journal_title：Behavioural pharmacology

authors： Wilson WM,Marsden CA

更新日期：1996-01-01 00:00:00

abstract：:Previous data indicate that ethanol intoxication (3 g/kg, intragastric) on postnatal day (PD) 7 and 8 increases ethanol acceptance, but on PD 10 and 11 generates an aversion in infant rats. We investigated the participation of the opioid system in these effects. Subcutaneous administration of naloxone (1 or 10 mg/kg) ...

journal_title：Behavioural pharmacology

authors： Gabriela Chotro M,Arias C

更新日期：2007-11-01 00:00:00

abstract：:This study examined interactions between cocaine and drugs that act as direct agonists at subtypes of "D2-like" dopamine receptors. The drugs 7-OH-DPAT, quinpirole and RU24213 were studied alone and in combination with cocaine for their effects on locomotor activity in non-habituated mice. Locomotor activity was measu...

journal_title：Behavioural pharmacology

authors： Tirelli E,Reggers J,Terry P

更新日期：1997-06-01 00:00:00

abstract：:Insufficient research has been carried out on the effects of repeated treatments with psychostimulants on agonistic behaviour. These effects were studied in mice using different schedules of administration and employing a low dose of amphetamine (1.5 mg/kg) which did not produce significant motor disruptions. After tw...

journal_title：Behavioural pharmacology

authors： Moro M,Salvador A,Simón VM

更新日期：1997-08-01 00:00:00

abstract：:The effects of µ agonists fentanyl, methadone and morphine and kappa agonist U50,488 on behavior maintained by negative reinforcement were determined. Rats were trained on concurrent schedules in which pressing one lever postponed shock on a Sidman avoidance schedule and pressing the other lever produced signaled peri...

journal_title：Behavioural pharmacology

authors： Galizio M,Robinson EG,Ordronneau C

更新日期：1994-04-01 00:00:00

abstract：:There is clinical and experimental evidence that treatment with immunosuppressive and antiproliferative drugs such as the calcineurin inhibitor cyclosporine A (CsA) is associated with mental health problems and neuropsychological disturbances in patients. However, it remains unclear whether and to what extent cognitiv...

journal_title：Behavioural pharmacology

authors： Kahl AL,Kirchhof J,Füting A,Hütter BO,Wilde B,Witzke O,Benson S,Hadamitzky M,Schedlowski M

更新日期：2017-06-01 00:00:00

abstract：:Ketamine is the prototype of a new generation of antidepressant drugs, which is reported in clinical studies to be effective in treatment-resistant patients, with an effect that appears within hours and lasts for a few days. Chronic mild stress (CMS) is a well-established and widely used animal model of depression, in...

journal_title：Behavioural pharmacology

authors： Papp M,Gruca P,Lason-Tyburkiewicz M,Willner P

更新日期：2017-02-01 00:00:00

abstract：:The effects on memory of drugs of abuse from several pharmacological classes were examined in four adult male squirrel monkeys responding under a delayed matching-to-sample schedule of food presentation. Subjects were required to emit 20 responses on a sample key transilluminated by either a constant white or a flashi...

journal_title：Behavioural pharmacology

authors： Baron SP,Wenger GR

更新日期：2001-07-01 00:00:00

abstract：:Dendrosomal nanocurcumin (DNC) is fabricated from esterification of oleic acid and polyethylene glycol residues with curcumin. DNC has shown antioxidant, neuroprotective, and neurogenesis-enhancing effects. In addition, it can attenuate morphine tolerance. Morphine self-administration is associated with neurodegenerat...

journal_title：Behavioural pharmacology

authors： Noroozi J,Hassanpour-Ezatti M,Alaei HA

更新日期：2017-12-01 00:00:00