Abstract:
BACKGROUND:The chronic myeloproliferative diseases (CMPDs) include chronic myelogenous leukemia (CML), primary (essential) thrombocythemia (PT), agnogenic myeloid metaplasia (AMM), and polycythemia vera (PV). Certain hematological malignancies have a different prevalence in our country than in countries with Caucasian populations. Data indicate that the prevalence of CML in our country is similar to that found in Caucasians; however, the prevalence of the other CMPDs has not been studied. METHODS:In a total of 8069 individuals studied between June 1983 and March 2001 in the Centro de Hematologia y Medicina Interna de Puebla, we assessed the prevalence of CML, PT, AMM, and PV. Some of the clinical features of these individuals were also assessed. RESULTS AND CONCLUSIONS:Forty-nine patients with CML, 14 with PT, 7 with AMM, and 3 with PV were identified. The clinical presentations of these CMPDs were not different from those described in Caucasians. CONCLUSIONS:We found that CML was more than 3 times more frequent than PT, that both PV and AMM were exceptional, and that PT, AMM, and PV were significantly less frequent in Mexican than in Caucasian populations (P < .01).
journal_name
Int J Hematoljournal_title
International journal of hematologyauthors
Ruiz-Argüelles GJ,López-Martínez B,Lobato-Mendizábal E,Ruiz-Delgado GJdoi
10.1007/BF02982113subject
Has Abstractpub_date
2002-06-01 00:00:00pages
499-502issue
5eissn
0925-5710issn
1865-3774journal_volume
75pub_type
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