Abstract:
:Primary effusion lymphoma (PEL) is a rare type of extranodal lymphoma, typically of a B-cell origin, which presents as lymphomatous effusion with no nodal enlargement or tumor masses. The development PEL is universally associated with human herpes virus-8 (HHV-8) infection. Cases of HHV-8-negative primary lymphomatous effusion have recently been reported and referred to as HHV-8-unrelated PEL-like lymphoma. Some cases of this disease have been reported in iatrogenic immunocompromised patients. The mechanisms responsible for the inhibitory effects of the discontinuation of immunosuppressants other than methotrexate (MTX) against the disease, which have been demonstrated for MTX-associated lymphoproliferative disorders, have not yet been elucidated. We describe a case of PEL-like lymphoma that developed in the course of antisynthetase syndrome and was treated with tacrolimus. A single dose of systemic chemotherapy did not improve lymphomatous effusion, whereas the discontinuation of tacrolimus resulted in the long-term remission of this disease.
journal_name
Int J Hematoljournal_title
International journal of hematologyauthors
Okada K,Asakura S,Yano T,Kishimoto Tdoi
10.1007/s12185-018-2426-2subject
Has Abstractpub_date
2018-09-01 00:00:00pages
329-334issue
3eissn
0925-5710issn
1865-3774pii
10.1007/s12185-018-2426-2journal_volume
108pub_type
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
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journal_title:International journal of hematology
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journal_title:International journal of hematology
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journal_title:International journal of hematology
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pub_type: 杂志文章,多中心研究
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journal_title:International journal of hematology
pub_type: 杂志文章
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-018-2464-9
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journal_title:International journal of hematology
pub_type: 信件
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journal_title:International journal of hematology
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
doi:10.1532/ijh97.04094
更新日期:2004-08-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-008-0144-x
更新日期:2008-10-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-016-1955-9
更新日期:2016-05-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-015-1885-y
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pub_type: 杂志文章
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journal_title:International journal of hematology
pub_type: 杂志文章
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journal_title:International journal of hematology
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-017-2233-1
更新日期:2017-08-01 00:00:00
abstract::The t(14;19)(q32;q13) is a recurring translocation found in some patients with chronic lymphocytic leukemia (CLL), and the t(14;19) juxtaposes the BCL3 gene on chromosome 19 with the immunoglobulin heavy chain gene (IGH) locus on chromosome 14. Genomic DNAs from 49 patients with chronic B-cell leukemia and the related...
journal_title:International journal of hematology
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
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journal_title:International journal of hematology
pub_type: 临床试验,杂志文章
doi:10.1007/s12185-018-2507-2
更新日期:2018-10-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:10.1007/s12185-019-02645-7
更新日期:2019-06-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
doi:10.1007/BF03165086
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journal_title:International journal of hematology
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Graft-versus-host disease (GVHD) and graft-versus leukemia (GVL) effects are closely related to each other after allogeneic stem cell transplantation. This association exists because of the extensive and complicated interaction between cellular donor components and recipient components concomitant with cytokine storms...
journal_title:International journal of hematology
pub_type: 杂志文章,评审
doi:10.1007/BF02983991
更新日期:2005-01-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
doi:10.1007/s12185-015-1761-9
更新日期:2015-04-01 00:00:00