Abstract：
:A good CD8+ response is required for immunity to many intracellular pathogens. Traditional antigen delivery using isolated sub-units or killed pathogens and adjuvant stimulates strong antibody responses but weak T-cell reactivity. Attenuated vaccines are usually more effective. The prime-boost delivery system based on immunisation with a naked DNA antigen-gene construct followed by boosting with an attenuated vaccinia virus expressing the same antigen is proving to be a powerful way to stimulate antigen-specific CD8 responses. Success using single epitopes is possible in malaria and we believe this approach holds much promise for other apicomplexan parasites such as Theileria spp.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Hall R,Adamson R,Boulter Ndoi
10.1007/s00436-001-0572-5subject
Has Abstractpub_date
2002-05-01 00:00:00pages
S45-7issue
13 Suppl 1eissn
0932-0113issn
1432-1955journal_volume
88pub_type
杂志文章,评审abstract：:Trichomonas gallinae are parasitic flagellates of importance in wild and domestic birds. The parasite is worldwide distributed, and Columbine birds are its main host. Current research focuses mostly on epidemiological and phylogenetic studies. However, there is still a lack of knowledge regarding parasite-host interac...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06887-x
更新日期：2020-11-01 00:00:00
abstract：:Nematodes of the family Aspidoderidae (Nematoda: Heterakoidea) Freitas 1956 are widely distributed from Americas. The species of the genus Aspidodera Railliet and Henry 1912 are parasites of mammals of the orders Edentata, Marsupialia, and Rodentia. In the present work, Aspidodera raillieti (L. Travassos, Mem Inst Osw...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0641-5
更新日期：2007-10-01 00:00:00
abstract：:Trichinella spiralis infection results in the transformation of muscle cells into a new, non-muscular cell called the nurse cell, and the nurse cell-muscle larva complex is finally created. To investigate whether T. spiralis infectivity is NBL age-dependent, five groups of synchronous newborn larvae (sNBL) were obtain...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050550
更新日期：1999-04-01 00:00:00
abstract：:Flame atomic absorption spectrometry was performed to determine the alteration of calcium concentration in the soft parts and shells of Biomphalaria alexandrina and Bulinus truncatus due to the infection with Schistosoma mansoni and S. haematobium, respectively. The results showed significant lowering in the calcium c...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0566-z
更新日期：2007-09-01 00:00:00
abstract：:A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1017-1
更新日期：2008-08-01 00:00:00
abstract：:The experimental transmission of a recently identified new Theileria (China 1) species pathogenic for sheep and goats in northern China is described. Haemaphysalis qinghaiensis nymphs and adults developed from larvae and nymph engorged on sheep infected with Theileria sp. (China 1) were able to respectively transmit t...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0509-8
更新日期：2007-08-01 00:00:00
abstract：:The present investigation was undertaken to identify and characterize trophozoite proteases of five axenic strains of Giardia duodenalis isolated in Brazil and the reference strain Portland 1 isolated in the United States. Trophozoite cell lysates of each strain were analysed for the pattern of proteins and for proteo...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-0124-5
更新日期：2006-07-01 00:00:00
abstract：:Balamuthia mandrillaris is a free-living ameba and an opportunistic agent of lethal granulomatous amebic encephalitis (GAE) in humans and other mammals. Its supposed routes of infection have been largely assumed from what is known about Acanthamoeba spp. and Naegleria fowleri, other free-living amebae and opportunisti...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1163-z
更新日期：2004-09-01 00:00:00
abstract：:The round goby Neogobius melanostomus is a bottom-dwelling fish native for the Ponto-Caspian basin, which started to colonize the Baltic Sea since 1991. The parasites of this fish species in the southwestern Baltic region are studied for the first time. The round goby in the SW Baltic Sea was infected with 12 parasite...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2321-8
更新日期：2011-09-01 00:00:00
abstract：:We tested whether biogeographic patterns characteristic of species diversity and composition may also apply to community assembly by investigating geographic variation in the pattern (PSA) (aggregation versus segregation) and strength of species associations (SSA) in flea and mite communities harbored by small mammali...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06255-4
更新日期：2019-04-01 00:00:00
abstract：:Hepatozoon canis is a tick-borne pathogen of canids, which is distributed worldwide. However, very little is known about this protozoan parasite in Pakistan. This study provides the first molecular evidence of H. canis from farm dogs from three agro-ecological zones of Punjab, Pakistan. A conventional PCR targeting th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5790-1
更新日期：2018-04-01 00:00:00
abstract：:The purpose of our study was to assess the effects of experimental dicroceliosis on the antioxidant defense capability of the liver in hamsters. Studies were carried out at 80 and 120 days after infection with an oral dose of 40 metacercariae of Dicrocoelium dendriticum. The parasitic pathology was ascertained by the ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050579
更新日期：1999-06-01 00:00:00
abstract：:Trypanosoma cruzi can modulate a large number of host intracellular responses during its invasion. GTPases such as RhoA, Rac1 and Cdc42 are examples of molecules that could be activated at this moment and trigger changes in the pattern of F-actin cytoskeleton leading to the formation of structures like stress fibers, ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1333-7
更新日期：2005-06-01 00:00:00
abstract：:Infection with helminth parasites or the administration of their antigens can prevent or attenuate autoimmune diseases. To date, the specific molecules that prime the amelioration are only limited. In this study, recombinant Schistosoma japonicum cystatin (rSjcystatin) and fructose-1,6-bisphosphate aldolase (rSjFBPA) ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06511-7
更新日期：2020-01-01 00:00:00
abstract：:Sarcophagids are a large family of Diptera, with a worldwide distribution. They are related to decomposing organic matter and are very interesting for health science and in forensic cases since many species produce myiasis and occur in human corpses. This family is considered difficult to study, particularly with rega...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4631-8
更新日期：2015-11-01 00:00:00
abstract：:The present study reports on the antifilarial activity of a marine sponge Haliclona exigua (phylum Porifera). The crude methanol extract and n-butanol-soluble fraction killed adult Brugia malayi at 31.25-microg/ml concentration (both in motility and 3-(4,5 dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide assay) ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1555-1
更新日期：2009-10-01 00:00:00
abstract：:Filter-feeding molluscan shellfish can concentrate environmentally derived waterborne pathogens of humans, which can be utilized in the sanitary assessment of water quality. In the present study, oocysts of Cryptosporidium were detected in Bent mussels (Ischadium recurvum) at two Chesapeake Bay sites from which C. par...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050590
更新日期：1999-07-01 00:00:00
abstract：:Toxoplasma gondii is an important zoonotic protozoan of the phylum Apicomplexa that can infect nearly all warm-blooded animals. The parasite can exist as the interconvertible tachyzoite or bradyzoite forms, leading to acute or latent infection, respectively. No drug has been reported to penetrate the cyst wall and red...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06722-3
更新日期：2020-07-01 00:00:00
abstract：:In the present article, we report on the identification of Vermamoeba (Hartmannella) vermiformis as the etiological agent of a tissue infection close to the eye of a female patient. Laboratory examination revealed no involvement of any pathogenic bacteria or fungi in the tissue infection. V. vermiformis was identified...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06312-y
更新日期：2019-06-01 00:00:00
abstract：:A new neogregarine pathogen of the great spruce bark beetle, Dendroctonus micans (Coleoptera: Curculionidae, Scolytinae), is described based on light microscopy and ultrastructural characteristics. The pathogen infects the fat body and the hemolymph of the beetle. The infection was nonsynchronous so that different dev...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4497-9
更新日期：2015-08-01 00:00:00
abstract：:The ultrastructure of alpha-bacteroids in relation to the fat-body cells of the lantern bug Pyrops candelaria was described. The fat-body-cell cytoplasm contained numerous mitochondria, rough endoplasmic reticula, vacuoles, and storage granules. Its nucleus had scattered chromatin materials. The alpha-bacteroid was en...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050287
更新日期：1997-01-01 00:00:00
abstract：:The efficacy of emodepside plus toltrazuril (Procox® oral suspension for dogs) against different species of gastrointestinal nematodes (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala) was evaluated in nine randomised,blinded and placebo-controlled laboratory studies in naturally or experimentally infected...
journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00436-011-2397-1
更新日期：2011-08-01 00:00:00
abstract：:Toxoplasma gondii is of public health and veterinary importance causing severe diseases in immunocompromised individuals including HIV/AIDS patients and in congenital cases and animals. There is limited information on the epidemiology of T. gondii infection in humans, particularly HIV patients and food animals and the...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5442-x
更新日期：2017-06-01 00:00:00
abstract：:The present study describes a transmission electron microscopical investigation of trophozoites from Giardia lamblia clone GS/M-83-H7 after exposure to monoclonal antibody (MAb) G10/4. From previous studies it is known that this antibody immunoreacts with the parasite's major surface antigen VSP (variable surface prot...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050096
更新日期：1996-01-01 00:00:00
abstract：:The protozoan parasite Giardia duodenalis is known to infect humans and a wide range of animals globally. However, no studies on G. duodenalis infection in Bactrian camels have been reported. In the present study, in order to examine the prevalence and genetic diversity of G. duodenalis in Bactrian camels, 852 fecal s...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06905-y
更新日期：2020-11-01 00:00:00
abstract：:Sheared flagella from Giardia lamblia were freed from cytoskeleton fragments and other cell contaminants by centrifuging in a density gradient. The purified organelles contain many polypeptides, including a set of low-molecular-weight antigens [apparent molecular weights (MWs) = 31, 32, 34, 35 and 37 kD] in the same s...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00535140
更新日期：1988-01-01 00:00:00
abstract：:Aedes aegypti and Ae. albopictus are key vectors in the spread of arboviruses such as dengue, chikungunya, yellow fever, and Zika. Triatoma rubrofasciata is an "assassin bug" whose populations and association with humans have dramatically increased and may represent a serious health concern. Control of insect vectors ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06212-1
更新日期：2019-03-01 00:00:00
abstract：:Cryptosporidium spp. are common intestinal protozoa causing diarrhea in humans and a variety of animal species. With the recent development of fur industry, a large number of fur animals are farmed worldwide, especially in China. The existence of identical Cryptosporidium species/genotypes in humans and fur animals su...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5686-5
更新日期：2018-01-01 00:00:00
abstract：:A new nematode species, Philometra spicarae sp. n. (Philometridae), is described from a gravid female found in the abdominal cavity of spicarel, Spicara smaris (Linnaeus) (Centracanthidae, Perciformes), from the Ionian Sea off Sicily, Italy. The new species differs from most other Philometra spp. parasitic in the abdo...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1877-z
更新日期：2010-07-01 00:00:00
abstract：:Babesia motasi BQ1 (Lintan) was first isolated from Haemaphysalis qinghaiensis collected in Gannan Tibet Autonomous Region, Gansu province in April 2000. In this study, a total of 3,204 serum samples from small ruminants in 22 provinces located in different districts of China were tested for antibodies against merozoi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3310-x
更新日期：2013-06-01 00:00:00
