Abstract:
OBJECTIVES:To investigate the question of whether there is an association between workplace exposures and sociodemographic factors and mortality from non-malignant respiratory disease excluding influenza and pneumonia (NMRDxIP) among workers in a fibreglass wool manufacturing facility. METHODS:A case-control study with cases and controls derived from deaths recorded from the Kansas City plant in the Owens Corning mortality surveillance system. The cases are defined as decedents with NMRDxIP as the underlying cause of death. Matched, unadjusted odds ratios (ORs) were used to assess any association between NMRDxIP and cumulative exposure history and sociodemographic factors individually. Matched, adjusted ORs were obtained by conditional logistic regression to estimate the effect of any one variable while controlling for the effect of all the others. RESULTS:Results of the unadjusted analysis, considering variables one at a time, yielded no significant associations between NMRDxIP and any of the exposure or sociodemographic variables. The smoking OR was substantially increased (OR 5.09; 95%CI 0.65 to undeterimed). Also, there were no significant variables in a conditional logistic regression analysis in which all variables were simultaneously adjusted. ORs for respirable glass fibres were below unity at all concentrations of exposure in the adjusted analysis. For respirable silica there was no consistent relation across all exposure levels. The ORs increased through the first three exposure concentrations but decreased for the highest exposure. However, ORs although not significant, are greater than unity for all respirable concentrations of silica exposure. CONCLUSIONS:The findings for Kansas City show no association between respirable glass fibres and NMRDxIP. The adjusted ORs for all exposures to respirable fibres were less than unity. On the other hand, the ORs for silica exposures were all above unity although there was no clear dose-response relation and none of the ORs were significant. Exposures for all substances considered were very low. Further, given the number of cases and controls, the statistical power to detect relatively small increases in risk, if any increase truly exited, was relatively low. The ORs for exposures to silica were all above unity although there was no clear dose-response relation and none of the ORs were significant. These raised ORs for silica suggest that continued surveillance would be prudent.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Chiazze L,Watkins DK,Fryar C,Fayerweather W,Kozono J,Biggs Vdoi
10.1136/oem.59.6.369subject
Has Abstractpub_date
2002-06-01 00:00:00pages
369-71issue
6eissn
1351-0711issn
1470-7926journal_volume
59pub_type
杂志文章abstract:OBJECTIVE:This study investigated the association between long-term exposure to black smoke (BS) air pollution and mortality in two related Scottish cohorts with 25 years of follow-up. METHODS:Risk factors were collected during 1970-1976 for 15331 and 6680 participants in the Renfrew/Paisley and Collaborative cohorts ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100600
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:To determine whether employees in the automobile industry in Michigan are at elevated risk of urinary bladder cancer. METHODS:The authors conducted a population-based case-control study including 418 cases and 571 controls. History of employment within the automobile industry was coded according to the US C...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041616
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:To explore the significance of the increase in urinary excretion of the lysosomal enzyme beta-N-acetylglucosaminidase (NAG) at low exposures to cadmium (Cd) that is frequently found in the absence of any other sign of renal dysfunction. METHODS:The activity was measured of the two main isoenzymes of NAG (NA...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.3.177
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVES:A medical surveillance programme was introduced into Ontario for workers exposed to diisocyanates in 1983, but no mandated surveillance programme is in effect in this province for other occupational respiratory sensitisers. This study assesses changes in incidence and severity of compensated claims for occup...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.1.58
更新日期:2002-01-01 00:00:00
abstract::Worldwide, millions of office workers use a computer. Reports of adverse health effects due to computer use have received considerable media attention. This systematic review summarises the evidence for a relationship between the duration of work time spent using the computer and the incidence of hand-arm and neck-sho...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.2006.026468
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:To investigate the occurrence of sick building syndrome in a tropical city, and its relation to indoor air quality and other factors. METHODS:2856 office workers in 56 randomly selected public and private sector buildings were surveyed. The study consisted of a self administered questionnaire assessing symp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.3.188
更新日期:1998-03-01 00:00:00
abstract::As part of an epidemiological study rat urinary aeroallergen (RUA) and total dust concentrations were measured at three research establishments. Personal RUA measurements in nine exposure groups over a workshift showed highest exposure for animal technicians (geometric mean (GM) = 32.4 micrograms/m3) and lowest for wo...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.9.593
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To obtain knowledge on male reproductive toxicity of inorganic lead at current European exposure levels and to establish lowest adverse effect levels, if any. METHODS:A cross sectional survey of the semen of 503 men employed by 10 companies was conducted in the United Kingdom, Italy, and Belgium. The mean b...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.59.4.234
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:To determine the kinetics of elimination of urinary dialkylphosphate metabolites after oral and dermally applied doses of the organophosphate pesticide chlorpyrifos to human volunteers and to determine whether these doses affected plasma and erythrocyte cholinesterase activity. METHOD:Five volunteers ingest...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.1.10
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence and incidence of upper extremity musculoskeletal pain (UEMP) and related disability among office workers in Costa Rica, Nicaragua and Spain. METHODS:Data from the multinational Cultural and Psychosocial Influences on Disability (CUPID) study on 947 (93%) participants at baseline w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-103327
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:Night shift work has been classified as a probable human carcinogen by the International Agency for Research on Cancer, based on experimental studies and limited evidence on human breast cancer risk. Evidence at other cancer sites is scarce. We evaluated the association between night shift work and stomach c...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103597
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:The aim was to test if targeting managers with an educational intervention reduces absence among pregnant employees. METHODS:The study was a non-blinded cluster randomised trial conducted in hospitals and daycare institutions from two administrative Danish Regions and two Danish municipalities. Clusters (wor...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2020-106794
更新日期:2021-01-12 00:00:00
abstract:OBJECTIVES:Male breast cancer is a rare disease of largely unknown aetiology. In addition to genetic and hormone-related risk factors, a large number of environmental chemicals are suspected of playing a role in breast cancer. The identification of occupations or occupational exposures associated with an increased inci...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2009.052175
更新日期:2010-12-01 00:00:00
abstract:AIMS:To investigate the concentration of urinary 8-hydroxydeoxyguanosine (8-OHdG) among electroplating workers in Taiwan. METHODS:Fifty workers were selected from five chromium (Cr) electroplating plants in central Taiwan. The 20 control subjects were office workers with no previous exposure to Cr. Urinary 8-OHdG conc...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.8.590
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:To confirm or refute the hypothesis that organic farmers have higher sperm concentrations than traditional farmers. METHODS:Traditional and organic farmers were selected randomly from central registers, and 171 traditional farmers and 85 organic farmers delivered one semen sample before the start of the spr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.2.139
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVES:Reliable retrospective exposure assessment continues to be a challenge in most population-based studies. Several methodologies exist for estimating exposures retrospectively, of which case-by-case expert assessment and job-exposure matrices (JEMs) are commonly used. This study evaluated the reliability of ex...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100556
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:The study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as surrogates for exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). METHODS:The report included workers exposed to diesel exhausts (low PAH exposure level, n = 39) as well as those exposed t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041418
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Controversy still exists about the breast carcinogenic properties in humans of environmental xenoestrogens (organochlorines), justifying new investigations. AIMS:To compare the blood levels of total dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB) in samples collected at the time of breast ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.5.348
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:To investigate the association between occupational exposure to disinfectants/antiseptics used for hand hygiene and asthma control in nurses. METHODS:In 2014, we invited female nurses with asthma drawn from the Nurses' Health Study II to complete two supplemental questionnaires on their occupation and asthm...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104740
更新日期:2018-05-01 00:00:00
abstract:AIMS:To examine the relation between the psychosocial work environment and the perceived indoor air problems measured by a questionnaire survey; and to discuss the role of a questionnaire as a means to enhance collaboration in the challenging multiprofessional process of solving indoor air problems. METHODS:The resear...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2002.005835
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:Introduced in the UK in 2010, the fit note was designed to address the problem of long-term sickness absence. We explored (1) associations between demographic variables and fit note receipt, 'maybe fit' use and long-term conditions, (2) whether individuals with long-term conditions receive more fit notes and...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-106035
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:To estimate the annual rates of self reported occupational asthma in different occupational groups in Sweden. METHODS:All claims of occupational asthma 1990-2 in the Swedish register of reported occupational diseases were classified according to occupation. The number of people employed in each occupational...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.11.757
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Few studies have investigated cancer risks in carbon black workers and the findings were inconclusive. METHODS:The current study explores the mortality of a cohort of 1535 male German blue-collar workers employed at a carbon black manufacturing plant for at least one year between 1960 and 1998. Vital status...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.026526
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:Most of the evidence on agreement between self- and proxy-reported occupational data comes from interview-based studies. The authors aimed to examine agreement between women's reports of their partner's occupation and their partner's own description using questionnaire-based data collected as a part of the p...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2009.052506
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To investigate the risk of cancer associated with exposure to air pollution among bus drivers and tramway employees. METHODS:A retrospective cohort study of 18,174 bus drivers or tramway employees in Copenhagen in the period 1900-94. Data on employment were obtained from company files. Information on cancer ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.9.594
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:To describe the methods used in the nuclear industry family study for which a comprehensive database has been assembled that links employment in the nuclear industry and dosimetry records to information on employees' reproductive health and the health of their children. To discuss the response rates and chara...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.12.793
更新日期:1999-12-01 00:00:00
abstract:AIMS:To investigate the longitudinal relation between strenuous leisure time physical activity and psychological complaints (depression and emotional exhaustion) in a Dutch working population in order to find evidence for the preventive role of physical activity in the development of psychological complaints. METHODS:...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2004.017541
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:Previous analyses of cataract in radiation-exposed populations have assessed relative risk; radiogenic excess additive risk (EAR), arguably of more public health importance, has not been estimated. Previous analysis of a large prospective cohort of US radiologic technologists (USRT) quantified excess relativ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105902
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Benzene is an established animal and human carcinogen. The mechanism of benzene toxicity, particularly its leukaemogenic effect, is not fully understood. The modified base 8-hydroxy-deoxyguanosine (8-OHdG) is a sensitive marker of the DNA damage due to hydroxyl radical attack at the C8 of guanine. This damag...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.11.739
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVES:To evaluate whether hourly changes in fine particle (PM(2.5), diameter<2.5 microm) exposure or outdoor particle concentrations are associated with rapid ischaemic responses. METHODS:41 non-smoking elderly people with coronary heart disease were followed up with biweekly clinic visits in Helsinki, Finland. T...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2007.037531
更新日期:2008-11-01 00:00:00